Isosorbide combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Analysis Abnormal Other Serious 10/30/2005 Female 194 lb 1/4/2006 United States
Primary
Concomitant
Hypotension Hospitalization 7/6/2005 Male 146 lb 10/17/2005 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2004 56 Female 190 lb 2/23/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 2/1/2001 54 Female 238 lb 2/23/2006 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 80 Female 134 lb 2/24/2006 Consumer United States
Primary
Concomitant
Drug Ineffective 80 Female 134 lb 3/7/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/1/2002 65 Male 3/8/2006 Physician United States
Primary
Concomitant
Drug Ineffective 80 Female 134 lb 3/9/2006 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 8/3/1999 56 Male 260 lb 3/14/2006 Lawyer United States
Primary
Concomitant
Myocardial Infarction Death 1/1/2006 Male 3/21/2006 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 1/1/1999 58 Female 170 lb 3/16/2006 United States
Primary
Concomitant
Renal Failure Other Serious 11/25/2000 58 Male 245 lb 3/28/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Disorder Other Serious 1/1/2000 64 Male 271 lb 4/3/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1/1/1999 54 Female 238 lb 4/3/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2004 62 Female 143 lb 4/5/2006 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/27/2002 65 Male 231 lb 4/5/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Death 1/1/2006 Male 4/5/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 6/1/2004 56 Female 190 lb 4/6/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Disorder Other Serious 1/1/2000 64 Male 271 lb 4/7/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 4/11/2006 88 Female 77 lb 4/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 42 Female 201 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Heart Rate Decreased Required Intervention 1/1/2000 83 Male 4/11/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/1/2006 Male 4/21/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2003 84 Female 141 lb 5/1/2006 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 Male 150 lb 4/25/2006 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 5/10/2005 73 Female 162 lb 5/25/2006 Physician United States
Primary
Concomitant
Tremor 3/17/2006 67 Male 5/30/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 5/30/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 6/1/2006 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 6/7/2006 Physician United States
Primary
Concomitant
Nervousness 6/1/2005 69 Female 139 lb 6/8/2006 Consumer United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 6/8/2006 Physician United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 6/9/2006 Physician United States
Primary
Concomitant
Urine Amphetamine Positive 2/9/2006 79 Male 5/5/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/10/2005 73 Female 162 lb 6/21/2006 Physician United States
Primary
Concomitant
Weight Increased Required Intervention 74 Female 6/23/2006 Physician United States
Primary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 7/10/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/6/2006 60 Male 198 lb 6/30/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 6/16/2006 66 Female 190 lb 6/29/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 5/10/2005 73 Female 162 lb 7/14/2006 Physician United States
Primary
Concomitant
Fluid Retention Male 7/21/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 3/1/2006 83 Male 176 lb 8/11/2006 Other Health Professional United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 73 Female 8/24/2006 Other Health Professional United States
Primary
Concomitant
Throat Irritation Other Serious 10/1/2005 73 Female 185 lb 8/30/2006 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Hospitalization 67 Male 7/10/2006 United States
Primary
Concomitant
Thrombosis Life Threatening 6/28/2006 78 Male 230 lb 8/25/2006 Pharmacist United States
Primary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 10/24/2006 Other Health Professional United States
Primary
Concomitant
Visual Disturbance Other Serious Female 301 lb 10/27/2006 Consumer United States
Primary
Secondary
Concomitant
Blood Pressure Increased 10/25/2005 56 Female 10/30/2006 Consumer United States
Primary
Concomitant
Haematuria Hospitalization 10/3/2006 Male 165 lb 10/31/2006 Consumer United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Hospitalization 5/18/2006 81 Male 237 lb 10/30/2006 Physician United States
Primary
Concomitant
Vision Blurred 71 Female 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Tinnitus 11/13/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2005 52 Male 11/13/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious Female 301 lb 11/20/2006 Consumer United States
Primary
Secondary
Concomitant
Thirst Other Serious 6/25/2006 69 Male 1/8/2007 Other Health Professional United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 12/1/2006 64 Male 1/23/2007 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious 1/26/2007 37 Female 302 lb 2/1/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/26/2007 37 Female 302 lb 2/14/2007 Consumer United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/28/2006 55 Male 146 lb 1/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 10/1/2006 82 3/19/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 3/26/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 12/1/2006 64 Male 3/30/2007 Pharmacist United States
Primary
Concomitant
Suicide Attempt Other Serious 8/31/2003 57 Male 4/11/2007 Consumer United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 3/1/2007 64 Female 220 lb 4/24/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/13/2007 48 Female 337 lb 5/3/2007 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 5/4/2007 Consumer United States
Primary
Concomitant
Cerebral Haemorrhage Required Intervention 5/6/2007 Female 270 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 2/1/2005 66 Female 2/14/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2008 47 Female 300 lb 7/22/2008 United States
Primary
Concomitant
Pneumonia Hospitalization 8/9/2008 Male 215 lb 8/13/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Heart Rate Decreased Hospitalization 7/5/2008 62 Female 8/22/2008 United States
Primary
Concomitant
Renal Impairment Other Serious 4/1/2006 53 Male 239 lb 8/29/2008 Lawyer United States
Primary
Concomitant
Bronchitis Other Serious Female 8/29/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 8/9/2008 Male 215 lb 8/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Bronchitis Other Serious 8/23/2008 Female 162 lb 9/9/2008 Other Health Professional United States
Primary
Concomitant
Myositis Hospitalization 10/3/2006 70 Male 9/16/2008 Physician United States
Primary
Concomitant
Somnambulism Other Serious 9/1/2008 Male 247 lb 9/24/2008 United States
Primary
Concomitant
Performance Status Decreased Hospitalization 9/6/2008 Male 208 lb 9/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 9/6/2008 Male 10/1/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/3/2008 United States
Primary
Secondary
Concomitant
Drug Hypersensitivity Hospitalization 8/1/2008 88 Male 9/25/2008 Pharmacist United States
Primary
Concomitant
Oropharyngeal Pain 10/29/2007 86 Female 10/7/2008 Consumer United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/7/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 1/1/2003 60 Female 160 lb 10/6/2008 Consumer United States
Primary
Concomitant
Pruritus Generalised Hospitalization 1/1/2002 Female 200 lb 10/15/2008 Physician United States
Primary
Concomitant
Palpitations Other Serious 1/1/2008 Female 130 lb 10/15/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Death 83 Male 10/21/2008 United States
Primary
Concomitant
Fluid Retention Hospitalization 7/28/2008 Female 10/30/2008 Physician United States
Primary
Concomitant
Ulcer Haemorrhage Other Serious 1/1/2008 78 Female 10/31/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 10/31/2008 United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 11/17/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 8/7/2008 Female 286 lb 11/18/2008 United States
Primary
Secondary
Concomitant
Lethargy Required Intervention 9/2/2008 77 Male 165 lb 10/15/2008 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Death 9/6/2008 Male 12/17/2008 Physician United States
Primary
Concomitant
Sinus Congestion 9/18/2008 80 Female 172 lb 12/18/2008 Physician United States
Primary
Concomitant
Dysuria 5/4/2008 83 Male 12/10/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 12/22/2008 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 12/22/2008 Consumer United States
Primary
Concomitant
Encephalopathy Hospitalization 7/7/2008 Female 286 lb 1/5/2009 Physician United States
Primary
Secondary
Concomitant
Fluid Overload Hospitalization 7/23/2008 Male 2/26/2009 Physician United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/6/2009 Consumer
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2007 79 Male 3/13/2009 United States
Primary
Concomitant
Rash 4/7/2008 78 Male 3/25/2009 Consumer United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 3/30/2009 Physician
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Death 27 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Death 27 Male 4/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 54 Male 4/2/2009 United States
Primary
Concomitant
Weight Decreased Life Threatening 2/5/2009 51 NotSpecified 150 lb 4/3/2009 United States
Primary
Concomitant
Weight Decreased Life Threatening 2/5/2009 51 Male 150 lb 4/20/2009 United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 10/1/2008 86 Female 115 lb 5/7/2009 United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2009 59 Male 5/14/2009 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 5/30/2007 Male 5/15/2009 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 10/1/2008 86 Female 115 lb 5/18/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 76 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Purple Glove Syndrome Hospitalization 11/3/2008 78 Female 161 lb 6/4/2009 Pharmacist United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 6/12/2009 Physician
Primary
Secondary
Concomitant
Photosensitivity Reaction 4/1/2009 Male 6/15/2009 Physician United States
Primary
Concomitant
Muscle Spasms 85 Female 6/19/2009 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 77 Male 6/18/2009 United States
Primary
Concomitant
Renal Neoplasm Hospitalization Female 7/1/2009 Consumer
Primary
Concomitant
Hyperuricaemia Hospitalization 4/7/2009 90 Male 7/7/2009 Other Health Professional Japan
Primary
Concomitant
Renal Neoplasm Hospitalization 5/1/2009 Female 180 lb 7/20/2009 Physician
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 296 lb 7/31/2009 Physician United States
Primary
Concomitant
Pain In Extremity Hospitalization 54 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 73 Male 8/5/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/4/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Venous Insufficiency Other Serious 3/13/2006 8/17/2009 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 77 Male 8/25/2009 Lawyer United States
Primary
Concomitant
Troponin Increased Hospitalization 54 Female 8/26/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 50 Male 8/31/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 68 Female 160 lb 8/31/2009 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Flatulence Other Serious 93 Male 150 lb 9/1/2009 Consumer United States
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 9/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 50 Male 9/4/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/4/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 76 Male 9/4/2009 Lawyer United States
Primary
Concomitant

Drug Data