Isosorbide Dinitrate combined with Zetia

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cardiac Arrest Other Serious 74 3/24/2006 Physician Switzerland
Primary
Concomitant
Myalgia Hospitalization 1/1/2006 65 Male 5/19/2006 Physician Germany
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/22/2006 Female 5/31/2006 Pharmacist United States
Primary
Concomitant
Myalgia Hospitalization 1/1/2006 65 Male 152 lb 6/14/2006 Physician Germany
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Hypoglycaemic Seizure Hospitalization 12/28/2005 71 Female 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 3/1/2005 75 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Other Serious 9/29/2006 62 Female 265 lb 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Drug Ineffective 2/23/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Rash 12/1/2006 56 Female 5/17/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 12/1/2006 Female 165 lb 6/28/2007 Physician United States
Primary
Concomitant
Sensory Loss Other Serious 12/1/2006 Male 266 lb 6/29/2007 Physician United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 7/1/2006 62 Male 163 lb 6/29/2007 Physician United States
Primary
Concomitant
Drug Ineffective Other Serious 5/5/2007 Male 190 lb 7/6/2007 Consumer United States
Primary
Secondary
Concomitant
Lip Swelling 73 Male 7/16/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 7/18/2007 60 Male 179 lb 7/19/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 5/5/2007 Male 190 lb 8/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Hepatitis Hospitalization 3/1/2005 61 Male 10/24/2007 Physician Netherlands
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 6/17/2007 69 Female 10/24/2007 Consumer United States
Primary
Concomitant
Stress Other Serious 9/1/2007 Female 175 lb 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Subdural Haematoma Life Threatening 12/8/2007 73 Female 12/26/2007 Pharmacist United States
Primary
Concomitant
Anaphylactic Reaction Hospitalization 8/10/2007 71 Female 1/3/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 12/1/2006 Female 1/29/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 9/20/2007 82 Male 3/4/2008 Pharmacist United States
Primary
Concomitant
Sensory Loss Other Serious 1/1/2004 Male 330 lb 3/7/2008 Physician United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 9/8/2007 75 Female 3/7/2008 United Kingdom
Primary
Concomitant
Drug Ineffective Other Serious 2/1/2008 Female 3/31/2008 Consumer United States
Primary
Concomitant
Insomnia 2/22/2008 49 Female 3/14/2008 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2008 85 Female 5/13/2008 Pharmacist United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/24/2007 80 Female 6/5/2008 United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 7/20/2007 52 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/3/2008 Male 12/12/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 9/30/2008 60 Male 12/26/2008 Other Health Professional France
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 1/16/2009 Lawyer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2005 Male 280 lb 1/16/2009 Consumer United States
Primary
Concomitant
Dyspnoea 5/9/2008 82 Male 165 lb 1/20/2009 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious Female 1/17/2009 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 2/19/2009 Lawyer United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 3/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Increased Hospitalization 10/17/2007 74 Female 5/1/2009 Physician Japan
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 5/29/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 6/9/2009 Consumer United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 6/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 6/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Death 81 Female 7/14/2009 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Hyperhidrosis Female 8/22/2009 United States
Primary
Concomitant
Flushing 2/20/2009 Male 8/22/2009 United States
Primary
Concomitant
Pruritus 1/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Paraesthesia Male 8/22/2009 United States
Primary
Concomitant
Flushing 10/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Hot Flush 4/28/2009 Female 8/22/2009 United States
Primary
Concomitant
Blood Glucose Increased 6/1/2009 Female 8/23/2009 United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 74 Male 209 lb 9/3/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 3/17/2010 Pharmacist United States
Primary
Concomitant
Wheelchair User Hospitalization 1/1/2009 61 Male 3/4/2010 Other Health Professional United States
Primary
Concomitant
Torsade De Pointes Hospitalization 3/24/2010 Pharmacist United States
Primary
Concomitant
Depression 1/1/2009 Female 3/16/2010 Pharmacist United States
Primary
Concomitant
Torsade De Pointes Hospitalization 4/5/2010 Physician United States
Primary
Concomitant
Death Death Female 4/16/2010 Physician United States
Primary
Concomitant
Gait Disturbance Hospitalization 10/1/2007 74 Female 6/7/2010 Physician Japan
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2006 82 Female 170 lb 6/9/2010 Consumer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting 1/3/2007 60 Female 280 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 4/1/2008 61 Male 196 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 8/23/2010 Lawyer United States
Primary
Concomitant
Torsade De Pointes Hospitalization 8/23/2010 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/4/2006 64 Male 9/2/2010 Physician Korea, Republic Of
Primary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 12/8/2010 Consumer United States
Primary
Concomitant
Dyspepsia Hospitalization 11/17/2010 60 Female 175 lb 1/5/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Death 11/12/2007 74 Female 1/12/2011 Lawyer United States
Primary
Concomitant
Erythema Other Serious 12/26/2007 50 Female 265 lb 2/3/2011 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 2/10/2011 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 2/1/2010 70 Female 227 lb 3/2/2011 Consumer United States
Primary
Concomitant
Oesophageal Pain 12/3/2010 67 Female 3/8/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Other Serious 11/12/2007 74 Female 3/9/2011 Lawyer United States
Primary
Concomitant
Injury Hospitalization 10/2/2005 52 Female 220 lb 3/23/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 10/2/2005 52 Female 220 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Decreased Appetite 1/28/2011 87 Male 3/25/2011 Consumer United States
Primary
Concomitant
Haemoglobin Decreased Hospitalization 2/12/2011 86 Female 150 lb 3/2/2011 Pharmacist United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/22/2011 76 Male 205 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Dizziness 3/1/2011 77 Female 3/31/2011 Consumer United States
Primary
Concomitant
Pain In Extremity 12/1/2010 89 Female 4/15/2011 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Odynophagia 1/1/2011 89 Female 4/25/2011 Consumer United States
Primary
Concomitant
Unevaluable Event 11/27/2010 73 Male 163 lb 2/7/2011 Consumer United States
Primary
Concomitant
Fall 3/1/2011 77 Female 5/9/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 64 Male 216 lb 5/24/2011 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 1/1/2005 57 Male 7/13/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain Other Serious 7/7/2006 73 Male 200 lb 7/13/2011 Other Health Professional United States
Primary
Concomitant
Death Other Serious 9/8/2006 63 Female 166 lb 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 5/1/2004 68 Female 7/22/2011 Consumer United States
Primary
Concomitant
Flushing 11/1/2010 67 Male 160 lb 8/5/2011 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 3/4/2009 60 Female 216 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 3/10/2007 65 Male 164 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 10/2/2005 52 Female 220 lb 9/15/2011 Other Health Professional United States
Primary
Concomitant
Coordination Abnormal Other Serious 4/30/1999 75 Male 245 lb 9/23/2011 Consumer United States
Primary
Concomitant
Appendicectomy Disability 5/1/2006 61 Male 220 lb 9/23/2011 Lawyer United States
Primary
Concomitant
Death Death 9/26/2011 87 Male 121 lb 10/6/2011 Physician United States
Primary
Concomitant
Accident Other Serious 65 Male 10/10/2011 United States
Primary
Concomitant
Accident Other Serious 65 Male 10/17/2011 United States
Primary
Concomitant
Upper Limb Fracture Life Threatening 65 Male 10/19/2011 United States
Primary
Concomitant
Asthenia Female 10/25/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspnoea Female 11/8/2011 Consumer United States
Primary
Secondary
Concomitant
Calculus Ureteric Life Threatening 6/11/2011 81 Male 11/14/2011 Japan
Primary
Concomitant
Renal Failure Death 12/11/2007 65 Male 11/29/2011 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 5/1/2004 68 Female 12/28/2011 Consumer United States
Primary
Concomitant
Bone Pain Hospitalization 5/1/2004 68 Female 1/18/2012 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 1/18/2012 65 Female 2/1/2012 Other Health Professional United States
Primary
Concomitant
Flatulence 1/3/2012 Male 2/1/2012 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 5/1/2004 68 Female 2/7/2012 Physician United States
Primary
Concomitant
Road Traffic Accident Death 1/18/2012 65 Female 2/14/2012 Other Health Professional United States
Primary
Concomitant
Back Pain Hospitalization Male 220 lb 2/16/2012 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2008 51 Male 194 lb 2/17/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 11/3/2011 65 Female 144 lb 2/24/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 11/3/2011 65 Female 144 lb 3/20/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 11/3/2011 65 Female 144 lb 3/29/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 1/18/2012 65 Female 4/6/2012 Consumer United States
Primary
Concomitant
Disease Progression Hospitalization 11/2/2011 65 Female 144 lb 4/13/2012 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 4/13/2012 86 Male 4/18/2012 Pharmacist Japan
Primary
Concomitant
Subclavian Artery Stenosis Hospitalization 82 Female 150 lb 4/6/2012 Lawyer United States
Primary
Concomitant
Cardiac Failure Acute Hospitalization 4/13/2012 86 Male 137 lb 4/27/2012 Pharmacist Japan
Primary
Concomitant
Blood Potassium Decreased Hospitalization 6/1/2011 4/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Pacemaker Insertion Other Serious Female 125 lb 5/2/2012 Consumer United States
Primary
Concomitant
Disease Progression Hospitalization 11/2/2011 65 Female 144 lb 5/4/2012 Physician United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 1/1/2011 72 Male 198 lb 5/7/2012 Consumer United States
Primary
Concomitant
Skin Discolouration Death 1/1/2007 69 Male 218 lb 5/8/2012 Physician United States
Primary
Secondary
Concomitant
Memory Impairment Other Serious 1/1/2011 72 Male 198 lb 5/9/2012 Consumer United States
Primary
Concomitant
Pleural Fibrosis Hospitalization 5/1/2004 68 Female 5/9/2012 Physician United States
Primary
Concomitant
Hypotension Other Serious Female 158 lb 5/10/2012 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 11/2/2011 65 Female 148 lb 5/16/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 65 Male 5/21/2012 Consumer United States
Primary
Concomitant
Road Traffic Accident Other Serious 1/18/2012 65 Female 5/23/2012 Other Health Professional United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening Male 165 lb 5/23/2012 Consumer United States
Primary
Concomitant
Emphysema Other Serious 1/1/2011 72 Male 198 lb 5/24/2012 Consumer United States
Primary
Concomitant

Drug Data