Isosorbide Dinitrate combined with Toprol-XL

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Other Serious 2/9/2004 75 Female 161 lb 3/21/2006 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 11/3/2000 70 Male 187 lb 3/27/2006 Physician United States
Primary
Concomitant
Dizziness 2/14/2006 66 Male 218 lb 4/17/2006 United States
Primary
Concomitant
Vomiting 2/9/2006 81 Female 201 lb 4/17/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 74 Female 8/9/2006 Consumer United States
Primary
Secondary
Concomitant
Skin Exfoliation 4/15/2006 83 Male 7/12/2006 United States
Primary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 2/7/2006 69 Female 181 lb 9/6/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 92 Male 6/12/2007 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 5/30/2007 Female 200 lb 6/13/2007 Consumer United States
Primary
Concomitant
Vision Blurred 11/15/2006 Female 232 lb 6/26/2007 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Depression Other Serious 1/1/2007 Female 144 lb 7/3/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 4/7/2007 67 Female 170 lb 7/24/2007 United States
Primary
Concomitant
Vascular Stent Insertion Other Serious 1/1/2006 Male 182 lb 7/30/2007 Physician United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious 2/3/2007 Female 8/10/2007 Consumer United States
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 12/30/2006 Male 214 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Cerebral Ischaemia Other Serious 8/1/2007 Female 136 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Limb Injury Other Serious 7/23/2007 Male 225 lb 9/24/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Male 9/20/2007
Primary
Concomitant
Contusion 74 Male 194 lb 10/4/2007 Consumer United States
Primary
Concomitant
Vision Blurred Male 11/12/2007 Consumer United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 8/13/2007 Male 160 lb 11/20/2007 Other Health Professional United States
Primary
Concomitant
Limb Injury Other Serious 7/23/2007 Male 225 lb 11/26/2007 Physician United States
Primary
Concomitant
Dyspnoea 67 Female 11/29/2007 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/21/2007 54 Male 188 lb 12/5/2007 Physician United States
Primary
Concomitant
Rash Other Serious 11/10/2006 Female 221 lb 12/6/2007 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 4/4/2007 Male 12/6/2007 Physician United States
Primary
Concomitant
Oedema Peripheral 3/1/2007 75 Female 12/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 3/1/2003 Female 200 lb 1/18/2008 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 6/1/2007 Female 144 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2003 Female 200 lb 1/25/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 199 lb 1/21/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 Female 245 lb 2/5/2008 Consumer United States
Primary
Concomitant
Vomiting 12/1/2007 55 Female 2/16/2008 United States
Primary
Concomitant
Ascites Other Serious 63 Female 180 lb 2/22/2008 United States
Primary
Concomitant
Vomiting 12/1/2007 55 Female 2/27/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/24/2008 78 Female 108 lb 3/3/2008 Consumer United States
Primary
Concomitant
Vomiting 10/1/2007 55 Female 3/4/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 3/14/2008 Consumer United States
Primary
Concomitant
Ascites Other Serious 9/1/2007 63 Female 233 lb 3/20/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 3/16/2008 Female 132 lb 3/31/2008 United States
Primary
Concomitant
Alopecia Female 4/18/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 4/28/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization Male 138 lb 5/2/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 5/8/2008 United States
Primary
Concomitant
Insomnia 2/22/2008 49 Female 3/14/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 5/20/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/1/2008 73 Female 148 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 65 Male 185 lb 7/18/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/15/2001 Female 200 lb 8/8/2008 Consumer United States
Primary
Concomitant
Hypotension Other Serious 5/1/2008 69 Female 180 lb 8/5/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 12/23/2008 Consumer United States
Primary
Concomitant
Lung Disorder Death 9/29/2008 50 Male 1/6/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 114 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
Death Death Male 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 5/1/2008 83 Female 1/26/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 8/4/2006 65 Male 261 lb 2/2/2009 Consumer United States
Primary
Concomitant
Medication Error Other Serious Female 114 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/1/2008 Female 158 lb 2/23/2009 Consumer United States
Primary
Concomitant
Heart Rate Irregular 75 Male 180 lb 4/21/2009 Consumer United States
Primary
Concomitant
Interacting
Heart Rate Irregular 80 Male 4/22/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/17/2007 57 Male 7/28/2009 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Renal Failure Other Serious 7/1/1998 41 Female 233 lb 7/27/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Hyperhidrosis Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 2/1/2008 Female 140 lb 8/22/2009 Physician United States
Primary
Concomitant
Vomiting 2/1/2009 Male 8/22/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 51 Female 353 lb 8/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2009 65 Male 8/26/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 52 Female 350 lb 9/1/2009 United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/27/2009 Female 179 lb 2/1/2010 Physician United States
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 3/13/2010 59 Female 4/1/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 4/6/2010 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/15/2008 79 Female 148 lb 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Female 4/16/2010 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 2/26/2010 58 Male 207 lb 5/21/2010 Physician United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 84 Male 7/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting 1/3/2007 60 Female 280 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Hypersomnia 3/1/2007 63 Male 7/12/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/1998 41 Female 218 lb 8/6/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 84 Male 9/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Palpitations Hospitalization Female 10/25/2010 Consumer United States
Primary
Concomitant
Dysphonia 76 Female 10/13/2010 Consumer United States
Primary
Concomitant
Rash 69 Female 10/13/2010 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 11/9/2010 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 9/1/2010 65 Male 11/11/2010 Consumer
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2010 55 Female 295 lb 11/16/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2008 84 Male 165 lb 11/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 9/11/2010 55 Female 295 lb 11/22/2010 Physician United States
Primary
Concomitant
Visual Impairment Other Serious 10/13/2009 Female 11/24/2010 Consumer United States
Primary
Secondary
Concomitant
Heart Rate Irregular Female 11/24/2010 Consumer
Primary
Secondary
Rheumatoid Arthritis Other Serious 1/1/2010 78 Female 107 lb 11/24/2010 Consumer United States
Primary
Concomitant
Malaise Hospitalization Female 11/24/2010 Physician United States
Primary
Concomitant
Spinal Fracture Other Serious Female 11/24/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Temporal Arteritis Other Serious Female 12/3/2010 Physician United States
Primary
Concomitant
Increased Tendency To Bruise 77 Female 169 lb 12/14/2010 United States
Primary
Concomitant
Psoriasis Other Serious 10/1/2009 58 Female 12/22/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 12/24/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 10/1/2009 58 Female 12/27/2010 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia 72 Female 185 lb 1/7/2011 Other Health Professional United States
Primary
Concomitant
Constipation 9/1/2010 65 Male 1/10/2011 Consumer
Primary
Concomitant
Cardiac Tamponade Life Threatening 9/7/2010 55 Female 295 lb 1/12/2011 Physician United States
Primary
Concomitant
Psoriasis Other Serious 10/1/2009 58 Female 1/25/2011 Physician United States
Primary
Secondary
Concomitant
Psoriasis Hospitalization 10/1/2009 58 Female 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Rash Papular 6/1/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Diarrhoea 8/13/2010 63 Female 1/29/2011 Consumer United States
Primary
Concomitant
Cough Other Serious 1/1/2011 61 Male 1/31/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2009 45 Female 2/4/2011 Pharmacist United States
Primary
Secondary
Concomitant
Nightmare 1/6/2011 56 Female 2/10/2011 Consumer United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/1/2001 52 Female 350 lb 3/3/2011 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 10/1/2007 78 Female 148 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Skin Swelling Other Serious 10/1/2007 78 Female 148 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 12/30/2010 89 Male 3/2/2011 Physician United States
Primary
Concomitant
Nausea Hospitalization 11/30/2010 74 Male 127 lb 3/17/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 12/29/2010 89 Male 3/17/2011 Physician United States
Primary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Deformity Other Serious 7/1/2005 74 Male 148 lb 4/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 10/18/2000 61 Male 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 45 Female 4/14/2011 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 10/1/2007 78 Female 148 lb 4/15/2011 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 11/30/2010 74 Male 127 lb 4/19/2011 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 61 Male 3/31/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 8/30/2003 54 Male 310 lb 4/21/2011 Physician United States
Primary
Concomitant
Gastric Haemorrhage Other Serious 4/1/2010 72 Male 230 lb 4/29/2011 Consumer United States
Primary
Concomitant
Pruritus Other Serious 7/1/2005 74 Male 148 lb 5/13/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infection Hospitalization 3/1/2011 60 Female 5/27/2011 Consumer United States
Primary
Concomitant