Isosorbide Dinitrate combined with Synthroid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting 2/9/2006 81 Female 201 lb 4/17/2006 Consumer United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 3/1/2006 61 Female 4/17/2006 Other Health Professional United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 5/8/2006 84 Male 146 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 5/8/2006 84 Male 146 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/2/2006 60 Male Pharmacist United States
Primary
Concomitant
Pruritus Hospitalization 1/1/2005 Male 8/8/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious 74 Female 8/9/2006 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2005 81 Male 247 lb 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/16/2004 82 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 12/1/2006 56 Female 5/17/2007 United States
Primary
Concomitant
Pruritus Hospitalization 12/1/2006 Female 165 lb 6/28/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 47 Female 4/26/2007 United States
Primary
Concomitant
Intraocular Pressure Increased Other Serious Female 140 lb 6/29/2007 Consumer United States
Primary
Concomitant
Nausea 9/1/2006 Female 7/26/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 7/18/2007 60 Male 179 lb 7/19/2007 Consumer United States
Primary
Concomitant
Vomiting 5/14/2007 86 Female 8/3/2007 Consumer United States
Primary
Concomitant
Cerebral Ischaemia Other Serious 8/1/2007 Female 136 lb 8/17/2007 United States
Primary
Secondary
Concomitant
Yellow Skin Other Serious 4/5/2006 87 Male 1/31/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Male 9/20/2007
Primary
Concomitant
Muscular Weakness 3/1/2006 76 Female 10/25/2007 Consumer United States
Primary
Concomitant
Pleural Effusion 10/9/2007 United States
Primary
Concomitant
Blood Pressure Increased Life Threatening 10/19/2006 Female 150 lb 11/6/2007 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/13/2007 Male 160 lb 11/20/2007 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased 9/14/2007 68 Male 11/16/2007 United States
Primary
Concomitant
Syncope 9/1/2007 Male 12/11/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/1992 36 Female 291 lb 12/17/2007 Consumer United States
Primary
Secondary
Concomitant
Urine Odour Abnormal Other Serious 11/1/2007 Female 153 lb 12/19/2007 Consumer United States
Primary
Concomitant
Syncope 9/1/2007 Male 1/4/2008 Consumer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/20/2007 Male 206 lb 1/8/2008 Other Health Professional United States
Primary
Concomitant
Blood Pressure Increased Life Threatening 10/19/2006 Female 150 lb 1/14/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 199 lb 1/21/2008 Consumer United States
Primary
Concomitant
Syncope 9/1/2007 Male 2/20/2008 Consumer United States
Primary
Secondary
Concomitant
Syncope 9/1/2007 Male 2/29/2008 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 4/28/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1992 36 Female 291 lb 5/1/2008 Consumer United States
Primary
Secondary
Concomitant
Myalgia Other Serious Female 5/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 5/8/2008 United States
Primary
Concomitant
Syncope 9/1/2007 Male 5/9/2008 Consumer United States
Primary
Secondary
Concomitant
Medication Error Other Serious 1/1/2008 Female 164 lb 5/16/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1969 Female 5/23/2008 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 2/23/2006 85 Male 5/27/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2008 50 Female 5/22/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 6/9/2008 Female 213 lb 7/17/2008 Physician United States
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 Female 111 lb 7/22/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/9/2008 Female 213 lb 7/24/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/25/2008 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Cyst Other Serious 4/10/2008 61 Female 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 7/21/2008 Female 171 lb 9/26/2008 Physician United States
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 61 Female 1/7/2009 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Required Intervention 9/1/2007 Female 9/17/2008 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization Female 179 lb 1/9/2009 Consumer United States
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 Female 111 lb 1/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 1/16/2009 Lawyer United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 12/24/2008 Female 179 lb 1/21/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious Female 1/17/2009 Physician United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2007 75 Male 225 lb 2/19/2009 Lawyer United States
Primary
Concomitant
Urticaria 4/1/2008 71 Female 4/30/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 5/29/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 6/9/2009 Consumer United States
Primary
Concomitant
Renal Failure Chronic Other Serious 5/21/2000 46 Male 260 lb 7/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/14/2009 Female 160 lb 7/24/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Weight Decreased 1/1/2009 54 Male 144 lb 7/22/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/13/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Speech Disorder Hospitalization 50 Male 8/14/2009 United States
Primary
Concomitant
Flushing Female 186 lb 8/22/2009 United States
Primary
Concomitant
Rash Macular 7/20/2009 Female 160 lb 8/23/2009 Consumer United States
Primary
Concomitant
Muscle Spasms 1/1/1990 Male 130 lb 8/25/2009 Consumer United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 8/1/2003 50 Female 218 lb 8/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Hyperhidrosis 5/14/2009 49 Male 8/29/2009 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2007 74 Male 209 lb 9/3/2009 Consumer United States
Primary
Concomitant
Death Death Female 4/16/2010 Physician United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/19/2007 64 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Diarrhoea 8/6/2009 63 Female 337 lb 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2000 42 Male 265 lb 8/26/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Weight Increased 4/1/2009 61 Female 106 lb 9/17/2010 Physician United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 1/1/1998 Female 9/27/2010 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/10/2010 67 Female 10/19/2010 Consumer United States
Primary
Concomitant
Renal Cyst Other Serious 61 Female 10/22/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Cyst Life Threatening 61 Female 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Urticaria 63 Female 10/13/2010 Consumer United States
Primary
Concomitant
Fatigue 79 Male 11/11/2010 Consumer United States
Primary
Concomitant
Eye Disorder Other Serious 2/5/2010 83 Female 11/10/2010 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 86 Female 11/18/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Product Quality Issue Other Serious 86 Female 12/17/2010 Consumer United States
Primary
Concomitant
Choking Other Serious 86 Female 1/6/2011 Consumer United States
Primary
Concomitant
Choking Other Serious 86 Female 1/12/2011 Consumer United States
Primary
Concomitant
Nail Discolouration Other Serious 86 Female 1/14/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 10/12/2010 60 Female 212 lb 1/20/2011 Physician United States
Primary
Secondary
Concomitant
Blood Disorder Other Serious 11/19/2007 64 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Foreign Body Other Serious 86 Female 1/28/2011 Consumer United States
Primary
Concomitant
Rash Papular 6/1/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 1/14/2011 70 Female 2/1/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nightmare 1/6/2011 56 Female 2/10/2011 Consumer United States
Primary
Concomitant
Lacrimation Increased 12/1/2010 78 Female 2/16/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 86 Female 2/23/2011 Consumer United States
Primary
Concomitant
Haemorrhage Hospitalization 1/19/2011 58 Female 235 lb 1/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Oropharyngeal Pain 12/1/2010 78 Female 2/25/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophageal Pain 12/3/2010 67 Female 3/8/2011 Consumer United States
Primary
Concomitant
Gastric Bypass Other Serious Male 220 lb 3/22/2011 Pharmacist United States
Primary
Concomitant
Haematochezia 1/1/2011 78 Female 3/25/2011 Consumer United States
Primary
Secondary
Concomitant
Fluid Retention 12/1/2010 78 Female 3/25/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 2/22/2011 76 Male 205 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Emotional Distress Death 11/18/2005 80 Female 113 lb 4/6/2011 Lawyer United States
Primary
Concomitant
Dizziness 11/1/2010 87 Female 4/8/2011 Consumer United States
Primary
Concomitant
Sluggishness Hospitalization 1/15/2011 89 Female 4/19/2011 Consumer United States
Primary
Concomitant
Dizziness 4/6/2011 88 Female 4/22/2011 Consumer United States
Primary
Concomitant
Catheterisation Cardiac Other Serious 2/5/2010 83 Female 4/29/2011 Consumer United States
Primary
Concomitant
Nervousness 3/11/2011 81 Female 5/24/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 64 Male 216 lb 5/24/2011 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 3/30/2011 78 Female 5/19/2011 Consumer United States
Primary
Secondary
Concomitant
Aortic Dilatation Hospitalization 88 Female 6/20/2011 United States
Primary
Concomitant
Renal Failure Other Serious 12/3/2003 77 Female 7/15/2011 Other Health Professional United States
Primary
Concomitant
Epistaxis 1/1/2011 79 Female 150 lb 7/25/2011 Consumer United States
Primary
Secondary
Concomitant
Ulcer Haemorrhage Hospitalization 3/30/2011 78 Female 7/25/2011 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 72 Female 172 lb 7/26/2011 Consumer United States
Primary
Secondary
Concomitant
Headache Female 112 lb 8/5/2011 Consumer United States
Primary
Concomitant
Flushing Male 8/6/2011 Consumer United States
Primary
Concomitant
Dyspepsia 7/17/2011 82 Female 8/10/2011 Consumer United States
Primary
Concomitant
Adrenomegaly Hospitalization 8/14/2007 81 Male 172 lb 8/11/2011 Consumer United States
Primary
Concomitant
Heart Rate Increased Other Serious 3/10/2007 65 Male 164 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 7/1/2011 72 Female 172 lb 8/23/2011 Consumer United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/18/2010 73 Female 8/31/2011 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 52 Male 174 lb 9/2/2011 Consumer United States
Primary
Secondary
Concomitant
Pericardial Haemorrhage Death 1/14/2011 70 Female 9/23/2011 Consumer United States
Primary
Secondary
Concomitant
Anhedonia Disability 1/1/2006 62 Female 204 lb 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 5/18/2010 73 Female 10/4/2011 Physician United States
Primary
Concomitant
Death Death 9/26/2011 87 Male 121 lb 10/6/2011 Physician United States
Primary
Concomitant
Accident Other Serious 65 Male 10/10/2011 United States
Primary
Concomitant
Cerebral Disorder Hospitalization 9/1/2004 62 Male 170 lb 10/5/2011 Lawyer United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 8/1/2011 10/13/2011 Consumer United States
Primary
Concomitant
Accident Other Serious 65 Male 10/17/2011 United States
Primary
Concomitant
Upper Limb Fracture Life Threatening 65 Male 10/19/2011 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/14/2011 70 Female 10/21/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Pain Hospitalization 1/1/2010 75 Female 10/17/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/28/2011 86 Male 10/24/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 1/1/2010 75 Female 11/14/2011 Consumer United States
Primary
Concomitant
Eructation 7/17/2011 82 Female 11/18/2011 Consumer United States
Primary
Concomitant

Drug Data