Isosorbide Dinitrate combined with Spiriva

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypoglycaemic Seizure Hospitalization 12/28/2005 71 Female 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Procedural Pain Hospitalization 10/24/2006 87 Male 12/27/2006 Pharmacist Japan
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2007 Male 364 lb 6/18/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 4/7/2007 67 Female 170 lb 7/24/2007 United States
Primary
Concomitant
Optic Nerve Disorder Other Serious 3/1/2006 Male 7/27/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 7/26/2007 Male 200 lb 8/9/2007 Consumer United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/4/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 8/28/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
Dyspnoea 5/3/2007 Male 9/5/2007 Consumer United States
Primary
Concomitant
Weight Increased Life Threatening 6/1/2007 70 Male 8/31/2007 Germany
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/18/2007 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 9/1/2006 82 Female 10/4/2007 Consumer United States
Primary
Concomitant
Vision Blurred 8/7/2007 78 Female 170 lb 10/12/2007 Physician United States
Primary
Concomitant
Pleural Effusion 10/9/2007 United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 9/1/2006 82 Female 11/21/2007 Consumer United States
Primary
Concomitant
Dyspnoea 67 Female 11/29/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 9/1/2006 82 Female 12/3/2007 Consumer United States
Primary
Concomitant
Dyspnoea 11/1/2007 77 Male 12/5/2007 Consumer United States
Primary
Concomitant
Breast Pain 2/1/2007 64 Male 12/20/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 1/4/2008 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 9/28/2007 Female 1/14/2008 Consumer United States
Primary
Concomitant
Visual Disturbance 1/1/2008 Female 2/7/2008 Consumer United States
Primary
Concomitant
Confusional State Hospitalization 9/28/2007 Female 2/29/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/24/2008 78 Female 108 lb 3/3/2008 Consumer United States
Primary
Concomitant
Dyspnoea 67 Female 3/6/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 3/14/2008 Consumer United States
Primary
Concomitant
Generalised Erythema 3/3/2008 Female 3/26/2008 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 2/1/2008 58 Female 4/17/2008 United States
Primary
Concomitant
Dyspnoea 11/1/2007 77 Male 5/2/2008 Consumer United States
Primary
Concomitant
Myalgia Other Serious Female 5/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 5/20/2008 Physician United States
Primary
Concomitant
Rash Pruritic 5/26/2008 77 Female 6/30/2008 Consumer United States
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 Female 111 lb 7/22/2008 Physician United States
Primary
Secondary
Concomitant
Renal Cyst Other Serious 4/10/2008 61 Female 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 7/6/2008 Male 163 lb 8/14/2008
Primary
Secondary
Concomitant
Gait Disturbance Disability 74 Female 8/18/2008 Consumer Canada
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 61 Female 1/7/2009 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Required Intervention 9/1/2007 Female 9/17/2008 Consumer United States
Primary
Concomitant
Renal Cyst Other Serious 4/10/2008 Female 111 lb 1/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Product Quality Issue Hospitalization 1/1/2005 Male 280 lb 1/16/2009 Consumer United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 1/20/2009 Consumer
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/22/2009 Consumer Austria
Primary
Concomitant
Varicose Vein Ruptured Hospitalization 1/1/2007 Female 1/30/2009 Consumer
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2008 65 Male 198 lb 1/30/2009 Physician Austria
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 65 Female 160 lb 4/19/2009 United States
Primary
Concomitant
Pneumonia Hospitalization 2/5/2009 Male 121 lb 5/26/2009 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 2/5/2008 Male 121 lb 5/27/2009 Physician Japan
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 7/29/2009 Physician
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 9/7/2008 53 Male 243 lb 8/12/2009 United States
Primary
Concomitant
Speech Disorder Hospitalization 50 Male 8/14/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/1/2007 76 Female 8/25/2009 Consumer
Primary
Concomitant
Dyspnoea 6/7/2009 76 Female 8/25/2009 Consumer
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Death Death Female 138 lb 3/23/2010 Consumer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization Female 189 lb 4/1/2010 Physician United States
Primary
Concomitant
Middle Insomnia 3/11/2010 69 Male 4/7/2010 Consumer
Primary
Concomitant
Hepatic Cirrhosis Other Serious 2/22/2010 68 Male 4/9/2010 Consumer
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2009 79 Male 141 lb 6/2/2010 United States
Primary
Secondary
Concomitant
Death Death 3/16/2010 64 Female 138 lb 7/8/2010 Consumer United States
Primary
Concomitant
Vomiting 1/1/2006 58 Female 145 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Vascular Dementia Hospitalization 6/28/2010 72 Male 200 lb 10/15/2010 United States
Primary
Secondary
Concomitant
Renal Cyst Other Serious 61 Female 10/22/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Cyst Life Threatening 61 Female 10/22/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/1/2010 Female 11/15/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2010 78 Female 107 lb 11/24/2010 Consumer United States
Primary
Concomitant
Migraine 1/1/2008 63 Female 11/29/2010 Consumer
Primary
Concomitant
Gait Disturbance 87 Male 139 lb 12/8/2010 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2009 81 Female 12/9/2010 Consumer
Primary
Concomitant
Lip Swelling 12/1/2010 81 Male 1/10/2011 Consumer
Primary
Concomitant
Cough 10/1/2010 71 Male 1/14/2011 Consumer
Primary
Concomitant
Wheezing Other Serious 74 Female 1/18/2011 Consumer United States
Primary
Secondary
Concomitant
Rash Papular 6/1/2010 64 Female 1/29/2011 Consumer United States
Primary
Concomitant
Cough 6/1/2010 68 Female 199 lb 1/29/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Death 3/1/2010 2/8/2011 Physician United States
Primary
Concomitant
Collapse Of Lung Hospitalization 75 Male 2/11/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Life Threatening 1/1/2008 79 Male 2/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Small Cell Lung Cancer Stage Unspecified Other Serious 3/1/2010 3/9/2011 Pharmacist United States
Primary
Concomitant
Cough 10/1/2010 71 Male 3/10/2011 Consumer United States
Primary
Concomitant
Transplant Failure Other Serious 11/12/2009 67 Female 273 lb 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Atrial Flutter Hospitalization 11/12/2009 67 Female 273 lb 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Oropharyngeal Candidiasis Other Serious 74 Female 3/17/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/22/2011 76 Male 205 lb 3/11/2011 Pharmacist United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 1/1/2007 79 Male 174 lb 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Lip Swelling 3/1/2011 84 Male 4/26/2011 Consumer United States
Primary
Concomitant
Bronchospasm 10/1/2010 71 Male 5/3/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 82 Female 115 lb 5/3/2011 United States
Primary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious 3/17/2009 66 Female 273 lb 5/16/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Enzymes Increased Hospitalization 5/4/2011 59 Female 177 lb 5/4/2011 Physician United States
Primary
Concomitant
Mental Status Changes Other Serious 11/12/2009 67 Female 273 lb 5/25/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lung Infection Hospitalization 3/1/2011 60 Female 5/27/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Hospitalization 1/1/2011 68 Male 237 lb 6/20/2011 Pharmacist United States
Primary
Concomitant
Lung Infection Hospitalization 3/1/2011 60 Female 7/19/2011 Consumer United States
Primary
Concomitant
Embolism Death 6/24/2011 73 Female 7/18/2011 Pharmacist United States
Primary
Concomitant
Pulseless Electrical Activity Death 73 Female 7/25/2011 Physician United States
Primary
Concomitant
Blood Glucose Increased 7/1/2010 82 Female 168 lb 8/5/2011 Consumer United States
Primary
Concomitant
Adrenomegaly Hospitalization 8/14/2007 81 Male 172 lb 8/11/2011 Consumer United States
Primary
Concomitant
Inflammatory Bowel Disease Hospitalization 2/1/2011 62 Female 163 lb 8/24/2011 Physician United States
Primary
Concomitant
Drug Ineffective 6/18/2011 76 Male 9/1/2011 Consumer United States
Primary
Concomitant
Retching Other Serious 6/1/2011 Female 135 lb 9/1/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/26/2010 68 Female 324 lb 9/7/2011 Physician Japan
Primary
Concomitant
Myocardial Infarction Death 1/1/2007 71 Male 9/14/2011 Physician Mexico
Primary
Concomitant
Fungal Infection 8/1/2011 66 Male 9/29/2011 Consumer United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 8/1/2011 10/13/2011 Consumer United States
Primary
Concomitant
Vasodilatation Hospitalization 3/17/2009 66 Female 273 lb 10/18/2011 Physician United States
Primary
Secondary
Concomitant
Haemodynamic Instability Other Serious 11/12/2009 67 Female 273 lb 10/24/2011 Physician United States
Primary
Secondary
Concomitant
Asthenia Female 10/25/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 12/1/2010 83 Female 10/24/2011 Consumer United States
Primary
Concomitant
Blood Glucose Increased 5/28/2011 86 Male 10/24/2011 Consumer United States
Primary
Concomitant
Dysphonia 8/1/2011 66 Male 237 lb 10/28/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Female 11/8/2011 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2011 57 Female 12/5/2011 Consumer United States
Primary
Secondary
Concomitant
Insomnia Male 12/8/2011 Consumer United States
Primary
Concomitant
Nausea 4/1/2007 55 Female 190 lb 12/12/2011 Consumer United States
Primary
Concomitant
Bundle Branch Block Left Life Threatening 65 Male 208 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Body Mass Index Decreased Hospitalization 8/1/2011 75 Male 1/5/2012 Physician Brazil
Primary
Concomitant
Coronary Artery Disease Hospitalization Female 222 lb 1/6/2012 Physician United States
Primary
Concomitant
Dyspnoea 10/13/2011 72 Female 1/16/2012 Consumer United States
Primary
Concomitant
Accidental Exposure 1/11/2012 84 Female 1/18/2012 Consumer United States
Primary
Concomitant
Cough Hospitalization 11/9/2011 77 Male 1/18/2012 Physician United States
Primary
Concomitant
Dyspnoea 7/1/2011 72 Female 1/18/2012 Consumer United States
Primary
Concomitant
Dyspnoea 7/1/2011 72 Female 1/25/2012 Consumer United States
Primary
Concomitant
Incorrect Route Of Drug Administration 1/23/2012 83 Male 1/30/2012 Consumer United States
Primary
Concomitant
Deafness Bilateral Other Serious 1/1/2009 70 Female 2/1/2012 Consumer United States
Primary
Concomitant
Weight Decreased 4/1/2007 55 Female 190 lb 2/2/2012 Other Health Professional United States
Primary
Concomitant
Intentional Overdose Hospitalization 2/1/2009 62 Male 2/9/2012 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/23/2012 66 Male 2/10/2012 Consumer United States
Primary
Concomitant
Cataract 10/13/2011 72 Female 2/21/2012 Consumer United States
Primary
Concomitant
Blood Glucose Abnormal Hospitalization Male 180 lb 2/23/2012 Other Health Professional United States
Primary
Concomitant
No Adverse Event 10/1/2011 91 Female 115 lb 3/5/2012 Consumer United States
Primary
Concomitant
Depression Other Serious 2/1/2009 62 Male 3/6/2012 Lawyer United States
Primary
Concomitant
Cough Hospitalization 11/9/2011 77 Male 3/28/2012 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 10/6/2010 50 Male 5/18/2011 Physician United States
Primary
Concomitant
Constipation 3/21/2012 Male 4/10/2012 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 1/1/2009 77 Male 4/11/2012 Consumer United States
Primary
Concomitant
Incorrect Route Of Drug Administration 2/1/2012 72 Male 4/16/2012 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 72 Male 4/27/2012 Other Health Professional Netherlands
Primary
Concomitant
Blood Potassium Decreased Hospitalization 6/1/2011 4/30/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death Male 5/1/2012 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 9/7/2008 53 Male 237 lb 5/2/2012 Consumer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 4/13/2012 68 Male 5/4/2012 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening Male 165 lb 5/23/2012 Consumer United States
Primary
Concomitant
Fungal Infection Hospitalization Female 152 lb 5/21/2012 Lawyer United States
Primary
Concomitant
Abdominal Pain Upper 1/1/2012 83 Male 5/25/2012 Consumer United States
Primary
Concomitant

Drug Data