Isosorbide Dinitrate combined with Protonix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pulmonary Embolism Other Serious 1/1/2002 77 Female 110 lb 2/14/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2002 77 Female 110 lb 4/25/2006 Physician United States
Primary
Concomitant
Hypoglycaemic Seizure Hospitalization 12/28/2005 71 Female 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 5/21/2006 65 Male 185 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Thirst 63 Male 355 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 8/1/2006 69 Male 10/30/2006 Consumer United States
Primary
Concomitant
Depression Other Serious 1/1/2007 Female 144 lb 7/3/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 2/10/2006 59 Female 7/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 8/1/2006 Female 7/26/2007 Physician United States
Primary
Concomitant
Lethargy 9/22/2006 Female 150 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/4/2007 Consumer United States
Primary
Concomitant
Urticaria 8/16/2007 81 Female 9/18/2007 Consumer United States
Primary
Concomitant
Vision Blurred 8/7/2007 78 Female 170 lb 10/12/2007 Physician United States
Primary
Concomitant
Treatment Noncompliance Disability 1/27/2007 50 Male 274 lb 10/25/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/29/2007 Female 160 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Stress Other Serious 9/1/2007 Female 175 lb 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Vasoplegia Syndrome Death 7/21/2004 48 Male 217 lb 11/1/2007 Physician United States
Primary
Concomitant
Subdural Haematoma Life Threatening 12/8/2007 73 Female 12/26/2007 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Stomach Discomfort Hospitalization 12/1/2007 Female 2/26/2008 Consumer United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/2006 Female 3/31/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/9/2007 85 Female 150 lb 3/7/2008 United States
Primary
Concomitant
Occult Blood Positive Hospitalization 1/1/2008 Male 4/24/2008 Physician United States
Primary
Concomitant
Insomnia 2/22/2008 49 Female 3/14/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 185 lb 5/13/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 185 lb 6/2/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 5/1/2008 90 Male 161 lb 7/14/2008 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 5/28/2008 63 Male 7/16/2008 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Pain 3/13/2008 65 Female 7/24/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rash 4/5/2008 62 Male 220 lb 8/1/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 10/1/2007 Female 162 lb 12/23/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 Female 162 lb 12/24/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Required Intervention 9/1/2007 Female 9/17/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 65 Female 160 lb 4/19/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 93 Female 7/21/2009 United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 7/23/2003 49 Female 191 lb 7/30/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Unevaluable Event Death 72 Female 8/10/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/13/2009 Lawyer United States
Primary
Concomitant
Vomiting 2/1/2009 Male 8/22/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2009 65 Male 8/26/2009 Physician United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 11/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/29/2009 67 Male 174 lb 1/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Abnormal Hospitalization 10/29/2009 67 Male 174 lb 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 3/11/2010 Female 3/24/2010 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/9/2009 69 Male 293 lb 4/1/2010 Physician United States
Primary
Concomitant
Pruritus Other Serious 1/1/2008 78 Male 137 lb 4/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 9/9/2009 69 Male 293 lb 4/14/2010 Physician United States
Primary
Concomitant
Death Death 3/11/2010 81 Female 5/17/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 3/12/2010 92 Female 123 lb 3/16/2010 Pharmacist United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 8/1/2006 57 Male 192 lb 6/25/2010 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2000 42 Male 265 lb 8/26/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Weight Increased 4/1/2009 61 Female 106 lb 9/17/2010 Physician United States
Primary
Concomitant
Wrist Fracture Other Serious 93 Female 9/9/2010 United States
Primary
Concomitant
Thrombosis Other Serious 5/25/2010 54 Female 10/18/2010 Consumer United States
Primary
Concomitant
Palpitations Hospitalization Female 10/25/2010 Consumer United States
Primary
Concomitant
Drug Effect Decreased 64 Male 10/28/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Hospitalization 68 Male 303 lb 11/4/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 11/9/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 86 Female 11/11/2010 United States
Primary
Concomitant
Malaise Hospitalization Female 11/24/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 12/3/2010 Physician United States
Primary
Secondary
Concomitant
Thirst Death 12/15/2006 12/6/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 62 Male 11/17/2010 United States
Primary
Concomitant
Temporal Arteritis Other Serious Female 12/3/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 10/18/2000 61 Male 12/24/2010 Physician United States
Primary
Secondary
Concomitant
Lip Swelling 12/1/2010 81 Male 1/10/2011 Consumer
Primary
Concomitant
Renal Failure Acute Death 12/1/2007 70 Male 1/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mouth Ulceration Other Serious 6/1/2009 50 Female 158 lb 1/29/2011 Consumer United States
Primary
Concomitant
Toxicity To Various Agents Hospitalization 1/14/2011 70 Female 2/1/2011 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 2/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Lacrimation Increased 12/1/2010 78 Female 2/16/2011 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 12/6/2010 70 Female 160 lb 12/18/2010 Pharmacist United States
Primary
Concomitant
Oropharyngeal Pain 12/1/2010 78 Female 2/25/2011 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/14/2011 70 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Glucose Increased Hospitalization 2/10/2011 71 Male 278 lb 3/8/2011 Physician United States
Primary
Concomitant
Fluid Retention 12/1/2010 78 Female 3/25/2011 Consumer United States
Primary
Concomitant
Condition Aggravated Hospitalization 2/10/2011 71 Male 278 lb 3/23/2011 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 10/18/2000 61 Male 4/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Creatinine Abnormal Hospitalization 12/1/2009 46 Female 196 lb 4/20/2011 Consumer United States
Primary
Secondary
Concomitant
Back Pain Hospitalization 3/1/2000 39 Male 5/9/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 82 Female 115 lb 5/3/2011 United States
Primary
Concomitant
Congo-crimean Haemorrhagic Fever Other Serious 10/18/2000 61 Male 6/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Other Serious 7/1/2004 72 Male 220 lb 7/14/2011 Other Health Professional United States
Primary
Concomitant
Mobility Decreased Other Serious 12/1/2006 79 Male 187 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Rash Papular Other Serious 1/1/2005 72 Female 172 lb 7/16/2011 Other Health Professional United States
Primary
Concomitant
Atelectasis Hospitalization 10/18/2000 61 Male 7/19/2011 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/1/2006 79 Male 152 lb 7/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Hospitalization 7/1/2006 56 Female 237 lb 7/29/2011 Physician United States
Primary
Concomitant
Connective Tissue Disorder Other Serious 10/18/2000 61 Male 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Dysstasia Other Serious 10/1/2006 58 Male 145 lb 8/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Nasopharyngitis 1/1/2010 78 Male 270 lb 8/6/2011 Consumer United States
Primary
Concomitant
Cardiomyopathy Other Serious 10/18/2000 61 Male 8/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 3/10/2007 65 Male 164 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Anorectal Discomfort 8/15/2011 75 Male 9/22/2011 Consumer United States
Primary
Concomitant
Pericardial Haemorrhage Death 1/14/2011 70 Female 9/23/2011 Consumer United States
Primary
Secondary
Concomitant
Lobar Pneumonia Hospitalization 9/29/2011 61 Female 193 lb 9/30/2011 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/14/2011 70 Female 10/21/2011 Consumer United States
Primary
Secondary
Concomitant
Respiratory Alkalosis Hospitalization 10/14/2011 95 Female 10/21/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 10/14/2011 95 Female 11/9/2011 Physician United States
Primary
Secondary
Concomitant
Osteosclerosis Other Serious 10/18/2000 61 Male 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Death 12/11/2007 65 Male 11/29/2011 Consumer United States
Primary
Concomitant
Respiratory Alkalosis Hospitalization 10/14/2011 95 Female 12/16/2011 Physician United States
Primary
Secondary
Concomitant
Brain Natriuretic Peptide Increased Other Serious 78 Female 150 lb 12/8/2011 Lawyer United States
Primary
Concomitant
Arrhythmia Other Serious Male 200 lb 12/30/2011 Lawyer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/10/2011 71 Male 276 lb 1/20/2012 Physician United States
Primary
Concomitant
Epistaxis 8/15/2011 75 Male 1/24/2012 Consumer United States
Primary
Concomitant
Decreased Appetite Hospitalization Male 230 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious Female 197 lb 1/25/2012 Lawyer United States
Primary
Concomitant
Pancytopenia Other Serious 10/18/2000 61 Male 2/3/2012 Physician United States
Primary
Secondary
Concomitant
Back Pain Hospitalization Male 220 lb 2/16/2012 Consumer United States
Primary
Concomitant
Blood Glucose Abnormal Hospitalization Male 180 lb 2/23/2012 Other Health Professional United States
Primary
Concomitant
Blood Pressure Systolic Increased Hospitalization 5/11/2007 57 Male 200 lb 2/27/2012 Lawyer United States
Primary
Concomitant
Sinusitis Hospitalization 7/20/2008 78 Female 3/11/2012 Lawyer United States
Primary
Concomitant
Blood Electrolytes Abnormal Hospitalization 1/20/2011 67 Female 151 lb 3/23/2012 Physician United States
Primary
Concomitant
Wheezing Hospitalization 67 Male 180 lb 3/16/2012 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 112 lb 3/30/2012 Consumer United States
Primary
Concomitant
Central Obesity Other Serious 78 Male 149 lb 3/23/2012 Lawyer United States
Primary
Concomitant
Injury Death 8/10/2007 58 Male 181 lb 4/4/2012 Other Health Professional United States
Primary
Concomitant
Depression Death 3/1/2007 58 Male 181 lb 4/9/2012 Other Health Professional United States
Primary
Concomitant
Subclavian Artery Stenosis Hospitalization 82 Female 150 lb 4/6/2012 Lawyer United States
Primary
Concomitant
Pulse Abnormal Disability 60 Female 114 lb 4/23/2012 Consumer United States
Primary
Concomitant
Umbilical Hernia Hospitalization Male 286 lb 4/25/2012 Consumer United States
Primary
Concomitant
Death Death Male 5/1/2012 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 9/7/2008 53 Male 237 lb 5/2/2012 Consumer United States
Primary
Concomitant
Productive Cough Hospitalization 79 Male 166 lb 5/3/2012 Consumer United States
Primary
Concomitant
Rales Disability 78 Male 180 lb 5/10/2012 Consumer United States
Primary
Concomitant
Moaning Other Serious 1/1/2009 85 Female 255 lb 5/11/2012 Lawyer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 10/18/2000 61 Male 5/17/2012 Physician United States
Primary
Secondary
Concomitant
Carotid Artery Disease Death Female 108 lb 5/17/2012 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening Male 165 lb 5/23/2012 Consumer United States
Primary
Concomitant
Melaena Other Serious 10/5/2011 72 Male 172 lb 5/24/2012 Consumer United States
Primary
Concomitant
Fungal Infection Hospitalization Female 152 lb 5/21/2012 Lawyer United States
Primary
Concomitant
Flank Pain Hospitalization 10/18/2000 61 Male 6/8/2012 Physician United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Death 72 Female 169 lb 6/11/2012 Consumer United States
Primary
Concomitant
Calculus Urinary Hospitalization 73 Male 209 lb 6/12/2012 Consumer United States
Primary
Concomitant
Loss Of Employment Other Serious 52 Female 6/22/2012 Consumer United States
Primary
Secondary
Cerebrovascular Accident Other Serious 52 Female 6/22/2012 Consumer United States
Primary
Secondary
Myocardial Infarction Other Serious 52 Female 7/2/2012 Consumer United States
Primary
Secondary
Loss Of Employment Other Serious 52 Female 8/3/2012 Consumer United States
Primary
Secondary
Renal Failure Hospitalization 11/30/2011 69 Male 185 lb 5/17/2013 Consumer Us
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/15/2010 71 Female 137 lb 5/10/2013 Consumer Us
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/9/2013 77 Male 4/1/2013 Physician Us
Primary
Concomitant

Drug Data