Isosorbide Dinitrate combined with Norvasc

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Other Serious 9/1/2005 52 Male 1/12/2006 Physician Bulgaria
Primary
Concomitant
Syncope Hospitalization 7/17/2004 78 Male 170 lb 2/16/2006 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 9/4/2004 87 Male 161 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Somnolence Life Threatening 1/1/2006 56 Female 3/3/2006 Physician China
Primary
Concomitant
Fall Death 3/4/2006 78 Female 3/9/2006 Japan
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 12/27/2003 87 Male 161 lb 3/23/2006 Physician United States
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/3/2006 78 Female 3/23/2006 Japan
Primary
Concomitant
Sudden Death Death 3/3/2006 78 Female 4/13/2006 Japan
Primary
Concomitant
Rash Pruritic Hospitalization 3/1/2006 81 Male 6/29/2006 Physician Japan
Primary
Concomitant
Rash Hospitalization 3/1/2006 81 Male 7/7/2006 Physician Japan
Primary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 7/1/2006 Male 200 lb 8/25/2006 United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2004 89 Male 10/17/2006 Consumer Canada
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 2/23/2007 67 Female 5/17/2007 United States
Primary
Concomitant
Muscle Spasms Other Serious 1/1/2007 Male 364 lb 6/18/2007 Consumer United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Sick Sinus Syndrome Hospitalization 3/29/2007 Female 6/29/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 3/29/2007 Female 7/13/2007 Physician Japan
Primary
Secondary
Vomiting Hospitalization 3/29/2007 Female 7/11/2007 Physician Japan
Primary
Secondary
Vascular Stent Insertion Other Serious 1/1/2006 Male 182 lb 7/30/2007 Physician United States
Primary
Concomitant
Rash Pustular Other Serious 7/20/2007 Male 215 lb 8/7/2007 Consumer United States
Primary
Concomitant
Dyspnoea 5/3/2007 Male 9/5/2007 Consumer United States
Primary
Concomitant
Initial Insomnia 3/8/2007 65 Female 140 lb 8/13/2007 Physician United States
Primary
Concomitant
Paraesthesia Oral Hospitalization 8/8/2007 Female 10/11/2007 Consumer United States
Primary
Concomitant
Vision Blurred 8/7/2007 78 Female 170 lb 10/12/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/29/2007 76 Female 10/17/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Disability 1/27/2007 50 Male 274 lb 10/25/2007 Consumer United States
Primary
Concomitant
Stomatitis 7/4/2007 86 Female 10/26/2007 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 10/1/2007 Female 10/31/2007 Physician United States
Primary
Concomitant
Vision Blurred Male 11/12/2007 Consumer United States
Primary
Secondary
Concomitant
Flatulence 9/18/2007 87 Male 11/16/2007 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Other Serious 4/29/2007 76 Female 11/15/2007 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 7/1/2007 Female 11/21/2007 Physician United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Rash Pustular Other Serious 7/20/2007 Male 215 lb 12/7/2007 Consumer United States
Primary
Concomitant
Blood Pressure Decreased 2/9/2007 Female 12/11/2007 Consumer United States
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Death 2/1/2001 56 Male 123 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Required Intervention 12/7/2007 41 Male 168 lb 12/14/2007 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 9/6/2007 82 Female 10/17/2007 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 1/4/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 1/18/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 109 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/7/2008 Male 1/30/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 2/4/2008 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 Female 245 lb 2/5/2008 Consumer United States
Primary
Concomitant
Visual Disturbance 1/1/2008 Female 2/7/2008 Consumer United States
Primary
Concomitant
Flatulence 9/18/2007 87 Male 163 lb 2/13/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 109 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Vomiting 12/1/2007 55 Female 2/16/2008 United States
Primary
Concomitant
Rash Other Serious 9/6/2007 82 Female 1/4/2008 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 2/27/2008 Other Health Professional United States
Primary
Concomitant
Vomiting 12/1/2007 55 Female 2/27/2008 Consumer United States
Primary
Concomitant
Vomiting 10/1/2007 55 Female 3/4/2008 Other Health Professional United States
Primary
Concomitant
Rash 8/22/2007 84 Male 180 lb 2/15/2008 Physician United States
Primary
Concomitant
Very Low Density Lipoprotein Increased Other Serious 2/19/2008 Male 220 lb 3/10/2008 Consumer United States
Primary
Concomitant
Rash Pruritic 8/9/2007 100 Female 97 lb 8/9/2007 Consumer United States
Primary
Concomitant
Feeling Cold Disability 70 Male 3/13/2008 Physician Japan
Primary
Secondary
Generalised Oedema Hospitalization 12/19/2007 81 Female 112 lb 3/11/2008 Other Health Professional Japan
Primary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Feeling Cold Disability 73 Male 3/31/2008 Physician Japan
Primary
Secondary
Vomiting Other Serious 10/1/2007 59 Female 249 lb 4/11/2008 United States
Primary
Concomitant
Trismus Hospitalization 8/15/2007 69 Female 4/18/2008 Physician Japan
Primary
Concomitant
Visual Disturbance 3/31/2008 Female 5/1/2008 Consumer United States
Primary
Concomitant
Gait Disturbance Other Serious Male 165 lb 5/9/2008 Consumer United States
Primary
Concomitant
Visual Disturbance 3/31/2008 Female 128 lb 6/11/2008 Physician United States
Primary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 7/14/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2007 47 Female 300 lb 7/22/2008 Consumer United States
Primary
Concomitant
Visual Impairment 3/31/2008 Female 128 lb 8/1/2008 Physician United States
Primary
Concomitant
Pseudomembranous Colitis Other Serious 7/28/2008 94 Female 8/14/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 4/25/2007 77 Female 11/24/2008 Physician Japan
Primary
Concomitant
Urine Abnormality Hospitalization 5/1/2008 68 Female 215 lb 12/8/2008 Consumer United States
Primary
Concomitant
Pneumonia Death 8/1/2008 Female 201 lb 12/24/2008 Physician United States
Primary
Concomitant
Death Death Male 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 77 Female 4/13/2009 Canada
Primary
Concomitant
Hypertension Other Serious 4/1/2009 4/27/2009 Consumer Germany
Primary
Interacting
Hypertension Other Serious 4/1/2009 6/12/2009 Consumer Germany
Primary
Interacting
Wound Dehiscence Other Serious 7/10/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Injury Death 72 Female 7/14/2009 United States
Primary
Concomitant
Vomiting Death 81 Female 7/14/2009 United States
Primary
Concomitant
Diabetic Foot Other Serious 1/1/2004 45 Male 200 lb 7/29/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 1/6/2009 Male 7/30/2009 Consumer United States
Primary
Secondary
Concomitant
Temperature Difference Of Extremities Hospitalization 54 Female 8/5/2009 United States
Primary
Concomitant
Unevaluable Event Death 72 Female 8/10/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Pain 11/1/2008 Female 8/22/2009 United States
Primary
Concomitant
Blood Glucose Increased 6/1/2009 Female 8/23/2009 United States
Primary
Concomitant
Spinal Column Stenosis Other Serious 12/2/2003 68 Male 8/31/2009 Physician United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 11/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/29/2007 57 Male 104 lb 11/17/2009 Physician Japan
Primary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Ulcer Hospitalization 10/29/2009 67 Male 175 lb 12/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 12/31/2009 Physician United States
Primary
Concomitant
Toothache Hospitalization 1/1/2009 Female 12/17/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/22/2009 77 Male 154 lb 1/5/2010 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 Male 1/7/2010 Lawyer United States
Primary
Concomitant
Toothache Hospitalization 1/1/2009 84 Female 1/8/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/29/2009 67 Male 174 lb 1/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Hospitalization 4/1/2009 84 Female 2/11/2010 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Weight Abnormal Hospitalization 10/29/2009 67 Male 174 lb 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 73 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 4/6/2010 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/15/2008 79 Female 148 lb 4/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Other Serious Male 5/25/2010 United States
Primary
Concomitant
Sinusitis Other Serious Male 137 lb 6/2/2010 United States
Primary
Concomitant
Embolism Other Serious 12/8/2009 75 Female 5/27/2010 Physician Japan
Primary
Concomitant
Sinusitis Other Serious 6/16/2010 81 Male 137 lb 7/2/2010 United States
Primary
Concomitant
Vomiting 1/1/2006 58 Female 145 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Neuroendocrine Carcinoma Of The Skin Other Serious 6/1/2010 66 Male 8/16/2010 Physician Switzerland
Primary
Concomitant
Thrombosis Other Serious 5/25/2010 54 Female 10/18/2010 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 10/21/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 4/1/2010 84 Male 130 lb 11/8/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 69 Male 11/11/2010 Lawyer United States
Primary
Concomitant
Eye Disorder Other Serious 2/5/2010 83 Female 11/10/2010 Consumer United States
Primary
Concomitant
Heart Rate Irregular Female 11/24/2010 Consumer
Primary
Secondary
Spinal Fracture Other Serious Female 11/24/2010 Consumer United States
Primary
Concomitant
Increased Tendency To Bruise 77 Female 169 lb 12/14/2010 United States
Primary
Concomitant
Dysgeusia 72 Female 185 lb 1/7/2011 Other Health Professional United States
Primary
Concomitant
Frequent Bowel Movements 12/1/2010 86 Female 1/19/2011 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 1/14/2011 77 Male 1/21/2011 Consumer United States
Primary
Concomitant
Skin Exfoliation Other Serious 1/1/2004 61 Female 251 lb 1/28/2011 Physician United States
Primary
Concomitant
Drug Ineffective 4/1/2009 64 Female 98 lb 1/28/2011 United States
Primary
Concomitant
Cough Other Serious 1/1/2011 61 Male 1/31/2011 Consumer United States
Primary
Concomitant
Malnutrition Death 3/14/2009 69 Male 90 lb 2/1/2011 Physician Japan
Primary
Concomitant
Septic Shock Other Serious 3/14/2009 69 Male 90 lb 2/2/2011 Physician Japan
Primary
Concomitant
Swollen Tongue Other Serious 76 Female 2/10/2011 Physician United States
Primary
Concomitant
Lacrimation Increased 12/1/2010 78 Female 2/16/2011 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious Female 2/10/2011 Consumer United States
Primary
Concomitant
Septic Shock Other Serious 3/14/2009 69 Male 90 lb 2/22/2011 Other Health Professional Japan
Primary
Concomitant
Oropharyngeal Pain 12/1/2010 78 Female 2/25/2011 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/15/2009 68 Male 168 lb 2/25/2011 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Hospitalization 1/1/2001 52 Female 350 lb 3/3/2011 Consumer United States
Primary
Concomitant
Skin Tightness Other Serious 10/1/2007 78 Female 148 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Skin Swelling Other Serious 10/1/2007 78 Female 148 lb 3/10/2011 Physician United States
Primary
Secondary
Concomitant
Tongue Pigmentation Other Serious 76 Female 3/14/2011 Physician United States
Primary
Concomitant
Impaired Fasting Glucose 6/1/2009 82 Male 3/17/2011 Pharmacist United States
Primary
Concomitant
Gastric Bypass Other Serious Male 220 lb 3/22/2011 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 3/14/2009 69 Male 90 lb 3/23/2011 Physician Japan
Primary
Concomitant
Blood Glucose Increased 2/20/2011 75 Male 3/25/2011 Consumer United States
Primary
Concomitant
Supraventricular Extrasystoles Hospitalization 56 Male 3/9/2011 Consumer United States
Primary
Concomitant

Drug Data