Isosorbide Dinitrate combined with Nitroglycerin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Enzyme Increased 1/31/2001 47 Male 1/5/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 11/3/2005 60 Male 188 lb 11/4/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/27/2006 78 Male 152 lb 1/27/2006 Pharmacist United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/9/2004 75 Female 161 lb 3/21/2006 Lawyer United States
Primary
Concomitant
Cough Other Serious 2/21/2006 54 Male 181 lb 2/24/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/23/2006 Other Health Professional Italy
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2005 76 Female 3/30/2006 Other Health Professional Italy
Primary
Concomitant
Oral Intake Reduced Hospitalization 1/7/2006 86 Male 211 lb 1/19/2006 Pharmacist United States
Primary
Secondary
Prostate Examination Abnormal Hospitalization 1/1/2003 84 Male 201 lb 5/3/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 83 Male 201 lb 5/16/2006 Physician United States
Primary
Concomitant
Sudden Death Other Serious 5/8/2006 89 Male 150 lb 5/26/2006 Physician Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 5/16/2006 63 Male 164 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Dry Mouth Other Serious 4/3/2006 62 Male 207 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Required Intervention 6/27/2005 77 Male 155 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 7/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 6/2/2006 60 Male Pharmacist United States
Primary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 74 Female 8/9/2006 Consumer United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 1/1/2001 67 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/1996 80 Male 119 lb 8/15/2006 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/8/2006 78 Male 176 lb 8/15/2006 Bulgaria
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/21/2006 70 Male 189 lb 7/17/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 8/29/2006 81 Male 117 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Rash Other Serious 7/18/2006 74 Male 341 lb 7/18/2006 Pharmacist United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 10/20/2004 Female 12/28/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Cancer Other Serious 72 Male 250 lb 1/8/2007 Consumer United States
Primary
Concomitant
Neurological Symptom Other Serious 72 Male 250 lb 1/9/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 8/30/2006 70 Female 150 lb 1/18/2007 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 1/24/2005 Male 2/9/2007 Pharmacist United States
Primary
Secondary
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Sudden Death Death 11/8/2006 84 Male 157 lb 2/28/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 92 Male 6/12/2007 Consumer United States
Primary
Concomitant
Haemoglobin Decreased 1/16/2007 Male 6/26/2007 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 5/8/2006 78 Male 176 lb 6/25/2007 Bulgaria
Primary
Secondary
Concomitant
Nausea 9/1/2006 Female 7/26/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 Female 7/26/2007 Physician United States
Primary
Concomitant
Stent Placement Hospitalization Male 8/24/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 Female 8/27/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 8/28/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Required Intervention 12/2/2006 50 Female 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2007 Female 220 lb 9/11/2007 Physician United States
Primary
Concomitant
Haematochezia Other Serious 4/1/2007 Female 9/11/2007 Consumer United States
Primary
Concomitant
Nausea Other Serious 9/1/2007 54 Female 120 lb 9/20/2007 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2007 Female 220 lb 9/21/2007 Physician United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2007 Female 229 lb 10/4/2007 Consumer United States
Primary
Concomitant
Treatment Noncompliance Disability 1/27/2007 50 Male 274 lb 10/25/2007 Consumer United States
Primary
Concomitant
Haemorrhage Other Serious 10/15/2007 Male 10/26/2007 Pharmacist United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 10/1/2007 Female 10/31/2007 Physician United States
Primary
Concomitant
Prostatic Specific Antigen Increased Male 11/13/2007 Consumer United States
Primary
Concomitant
Fall 77 Male 11/14/2007 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 7/1/2007 Female 11/21/2007 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 11/21/2007 58 Male 279 lb 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 3/1/2007 Female 229 lb 12/11/2007 Consumer United States
Primary
Concomitant
Malaise Hospitalization 9/8/2007 75 Female 12/17/2007 United Kingdom
Primary
Concomitant
Rash Other Serious 9/6/2007 82 Female 10/17/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/11/2003 47 Female 261 lb 1/18/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 109 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 40 Female 1/15/2008 Japan
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 40 Female 1/15/2008 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 109 lb 2/15/2008 Other Health Professional United States
Primary
Concomitant
Rhinorrhoea Male 2/17/2008 United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Rash Other Serious 9/6/2007 82 Female 1/4/2008 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Rhinorrhoea Male 2/27/2008 Other Health Professional United States
Primary
Concomitant
Contrast Media Reaction 11/21/2007 65 Female 134 lb 3/4/2008 Other Health Professional United States
Primary
Concomitant
Back Pain 9/1/2007 83 Male 225 lb 10/5/2007 Consumer United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2006 Male 245 lb 3/11/2008 Other Health Professional United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 9/8/2007 75 Female 3/7/2008 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 10/1/2007 Female 3/21/2008 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 2/1/2008 58 Female 4/17/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 180 lb 4/22/2008 Consumer United States
Primary
Concomitant
Occult Blood Positive Hospitalization 1/1/2008 Male 4/24/2008 Physician United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/13/2008 Other Health Professional Japan
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2006 Male 245 lb 5/16/2008 Other Health Professional United States
Primary
Concomitant
Contrast Media Reaction 11/21/2007 65 Female 134 lb 5/19/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Other Serious 77 Male 112 lb 5/21/2008 Other Health Professional Japan
Primary
Concomitant
Hypotension Hospitalization 2/23/2006 85 Male 5/27/2008 Pharmacist United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/12/2008
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 6/25/2006 77 Male 6/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 4/3/2008 65 Female 134 lb 6/18/2008 Consumer United States
Primary
Concomitant
Contrast Media Reaction 11/21/2007 65 Female 134 lb 6/26/2008 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2008 Male 6/30/2008 Consumer United States
Primary
Concomitant
Diarrhoea 4/1/2007 Female 7/2/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Presyncope Other Serious 1/1/2000 Female 185 lb 7/15/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 7/18/2008 67 Male 187 lb 7/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/25/2007 47 Female 300 lb 7/22/2008 Consumer United States
Primary
Concomitant
Blue Toe Syndrome 2/2/2008 75 Male 7/29/2008 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 6/4/2008 Female 8/13/2008 Other Health Professional United States
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/27/2008 United States
Primary
Concomitant
Metabolic Disorder Hospitalization 80 Female 8/21/2008 Consumer Canada
Primary
Secondary
Concomitant
Visual Impairment Other Serious Male 140 lb 11/22/2008 Consumer United States
Primary
Concomitant
Fall Other Serious 9/1/2006 80 Female 12/1/2008
Primary
Secondary
Nausea Hospitalization 11/7/2008 55 Female 200 lb 12/4/2008 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/1999 Male 12/18/2008 Pharmacist Japan
Primary
Concomitant
Lung Disorder Death 9/29/2008 50 Male 1/6/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2005 Male 280 lb 1/16/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious Female 114 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 57 Male 256 lb 1/26/2009 Consumer United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 81 Female 1/29/2009 Consumer United Kingdom
Primary
Secondary
Myocardial Infarction Hospitalization 55 Male 226 lb 1/30/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 84 Female 1/24/2009 United States
Primary
Concomitant
Nausea Other Serious 1/1/2007 Male 232 lb 1/29/2009 Consumer United States
Primary
Concomitant
Medication Error Other Serious Female 114 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 55 Male 226 lb 2/9/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Hospitalization 84 Female 2/27/2009 Consumer United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 80 Female 3/4/2009 Canada
Primary
Concomitant
Hyponatraemia Other Serious 77 Female 4/13/2009 Canada
Primary
Concomitant
Sensory Disturbance Other Serious 4/21/2009 Other Health Professional Canada
Primary
Concomitant
Heart Rate Irregular 75 Male 180 lb 4/21/2009 Consumer United States
Primary
Concomitant
Interacting
Vision Blurred Hospitalization 84 Female 4/22/2009 United States
Primary
Concomitant
Nausea Other Serious 4/3/2009 Male 185 lb 4/28/2009 United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 5/29/2009 Consumer United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 6/9/2009 Consumer United States
Primary
Concomitant
Post Procedural Infection Other Serious 1/1/2009 69 Female 6/18/2009 Canada
Primary
Concomitant
Renal Failure Chronic Other Serious 5/21/2000 46 Male 260 lb 7/10/2009 United States
Primary
Concomitant
Renal Disorder Death 67 Male 7/14/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased 4/1/2009 Male 7/24/2009 Other Health Professional United States
Primary
Concomitant
Wrist Fracture Other Serious 93 Female 7/21/2009 United States
Primary
Concomitant
Fall Male 7/27/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Renal Failure Other Serious 7/1/1998 41 Female 233 lb 7/27/2009 United States
Primary
Concomitant
Stent Occlusion Other Serious 1/1/2009 Male 7/29/2009 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 64 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/10/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 9/7/2008 53 Male 243 lb 8/12/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Wrist Fracture Hospitalization 1/31/2007 93 Female 8/13/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Poor Peripheral Circulation Other Serious 5/31/2006 53 Female 198 lb 8/24/2009 United States
Primary
Concomitant
Paraesthesia Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation 7/16/2009 Male 225 lb 8/23/2009 United States
Primary
Concomitant
Flatulence Other Serious 93 Male 8/18/2009 Consumer United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 8/1/2003 50 Female 218 lb 8/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/25/2009 65 Male 180 lb 8/24/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/6/2000 51 Male 175 lb 10/5/2009 United States
Primary
Concomitant
Vomiting Other Serious 2/21/2008 69 Female 150 lb 10/29/2009 Lawyer United States
Primary
Concomitant
Muscle Spasms Other Serious 9/20/2009 Male 300 lb 10/20/2009 Consumer United States
Primary
Concomitant

Drug Data