Isosorbide Dinitrate combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wrong Technique In Drug Usage Process Death 12/11/2005 67 Male 1/18/2006 China
Primary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 12/13/2005 80 Male 171 lb 12/16/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Required Intervention 7/13/2005 56 Male 166 lb 2/3/2006 Other Health Professional United States
Primary
Secondary
Renal Disorder Hospitalization 9/4/2004 87 Male 161 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 12/13/2000 57 Female 179 lb 2/27/2006 Physician Germany
Primary
Concomitant
Myocardial Infarction Hospitalization 4/1/2004 60 Female 220 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 12/27/2003 87 Male 161 lb 3/23/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 10/1/2000 57 Female 179 lb 4/26/2006 Physician Germany
Primary
Concomitant
Renal Failure Acute Hospitalization 5/16/2006 63 Male 164 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemia Required Intervention 6/27/2005 77 Male 155 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Restrictive Pulmonary Disease Other Serious 5/8/2006 84 Male 146 lb 7/7/2006 Pharmacist United States
Primary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 64 Female 9/5/2006 Malaysia
Primary
Secondary
Delirium Hospitalization 66 Male 9/26/2006 Physician Switzerland
Primary
Concomitant
Sepsis Hospitalization 9/15/2006 75 Male 172 lb 10/2/2006 Physician Germany
Primary
Concomitant
Subileus Hospitalization 12/28/2004 85 Female 150 lb 10/4/2006 Other Health Professional Germany
Primary
Concomitant
Blood Creatinine Increased Hospitalization 4/13/2006 53 Male 167 lb 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Other Serious 12/14/2005 65 Female 190 lb 2/12/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/19/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 2/21/2007 Physician Poland
Primary
Concomitant
Somnolence Other Serious 5/1/2005 65 Female 190 lb 5/14/2007 Physician Poland
Primary
Concomitant
Syncope Other Serious 1/1/2005 65 Female 190 lb 5/16/2007 Physician Poland
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 54 Male 252 lb 10/23/2007 Physician Russian Federation
Primary
Concomitant
Nausea 8/23/2007 65 Male 203 lb 10/5/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/21/2007 58 Male 279 lb 11/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Other Serious 9/1/2007 Female 175 lb 12/7/2007 Consumer United States
Primary
Secondary
Concomitant
Underdose 1/1/2004 Male 241 lb 12/15/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/21/2007 Consumer United States
Primary
Concomitant
Syncope Other Serious 8/1/2004 65 Female 190 lb 1/9/2008 Physician Poland
Primary
Concomitant
Drug Ineffective 5/17/2007 75 Male 6/11/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/12/2008
Primary
Secondary
Concomitant
Wound Complication Other Serious 1/1/2000 Female 6/4/2008 Physician United States
Primary
Concomitant
Urine Abnormality Other Serious 4/7/2008 Male 225 lb 6/13/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/24/2007 80 Female 6/5/2008 United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/17/2008
Primary
Secondary
Concomitant
Diarrhoea Other Serious 4/3/2008 65 Female 134 lb 6/18/2008 Consumer United States
Primary
Concomitant
Urine Abnormality Other Serious 4/7/2008 Male 225 lb 6/23/2008 Consumer United States
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Rash Pruritic 5/26/2008 77 Female 6/30/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/24/2008 Male 194 lb 6/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 8/1/2004 65 Female 190 lb 7/7/2008 Physician Poland
Primary
Concomitant
Dilatation Ventricular Life Threatening 9/7/2007 Male 252 lb 7/21/2008 Physician Russian Federation
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/14/2007 59 Male 179 lb 7/29/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 7/27/2007 65 Male 201 lb 7/29/2008 Other Health Professional United States
Primary
Concomitant
Blue Toe Syndrome 2/2/2008 75 Male 7/29/2008 Consumer United States
Primary
Concomitant
Transaminases Increased Life Threatening 6/19/2008 Female 8/5/2008 United States
Primary
Concomitant
Psoriasis 6/1/2008 Male 215 lb 12/12/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 12/23/2008 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 10/1/2007 Female 162 lb 12/23/2008 Consumer United States
Primary
Concomitant
Rash Other Serious 7/6/2008 Male 174 lb 12/24/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2007 Female 162 lb 12/24/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 12/15/2008 55 Male 170 lb 1/13/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 55 Male 226 lb 1/30/2009 Lawyer United States
Primary
Concomitant
Varicose Vein Ruptured Hospitalization 1/1/2007 Female 1/30/2009 Consumer
Primary
Concomitant
Renal Failure Acute Hospitalization 2/19/2009 74 Male 196 lb 2/25/2009 Other Health Professional United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 65 Female 160 lb 4/19/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 64 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Social Problem Hospitalization 1/20/2006 73 Male 163 lb 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/12/2009 Consumer United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 7/1/2007 48 Male 8/12/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/28/2009 Male 198 lb 8/10/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 78 Female 8/14/2009 United States
Primary
Concomitant
Headache 9/7/2008 Male 214 lb 8/21/2009 United States
Primary
Concomitant
Skin Burning Sensation 9/1/2008 Male 8/21/2009 United States
Primary
Concomitant
Feeling Hot 9/10/2008 Male 8/22/2009 United States
Primary
Concomitant
Nausea 11/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Vision Blurred 8/20/2008 Male 8/21/2009 United States
Primary
Concomitant
Pruritus 1/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Paraesthesia Male 8/22/2009 United States
Primary
Concomitant
Skin Burning Sensation Female 8/22/2009 United States
Primary
Concomitant
Rash 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Hyperhidrosis Male 8/22/2009 United States
Primary
Concomitant
Flushing Male 8/22/2009 United States
Primary
Concomitant
Rash Macular 7/20/2009 Female 160 lb 8/23/2009 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Local Swelling 6/22/2009 Male 254 lb 8/29/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/25/2009 65 Male 180 lb 8/24/2009 Physician United States
Primary
Concomitant
Supraventricular Tachycardia Other Serious 56 Male 9/25/2009
Primary
Secondary
Coronary Artery Disease Hospitalization 9/22/2008 Male 10/7/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/26/2004 74 Male 12/17/2009 China
Primary
Concomitant
Syncope Hospitalization 12/21/2009 94 Male 163 lb 1/4/2010 Pharmacist United States
Primary
Secondary
Thrombocytopenia Other Serious 10/1/2007 Male 1/7/2010 Lawyer United States
Primary
Concomitant
Paraesthesia Other Serious Male 178 lb 1/8/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 10/23/2007 63 Female 141 lb 1/27/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 8/9/2009 Male 190 lb 1/28/2010 Other Health Professional United States
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 1/1/2010 Female 172 lb 3/31/2010 United States
Primary
Concomitant
Pain In Extremity Other Serious 10/1/2009 60 Female 4/26/2010 Consumer France
Primary
Secondary
Chest Pain Hospitalization 11/30/2009 63 Male 112 lb 5/12/2010 Physician Hong Kong
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2010 65 Male 5/24/2010 Physician
Primary
Secondary
Concomitant
Vomiting Other Serious 1/26/2008 53 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Renal Failure Acute Other Serious 11/2/2009 60 Male 5/27/2010 Pharmacist Malaysia
Primary
Concomitant
Rash Other Serious 7/6/2008 65 Male 174 lb 6/24/2010 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 1/19/2010 65 Male 6/30/2010 Physician
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 51 Male 8/25/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Medication Residue 6/1/2009 68 Female 185 lb 9/17/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Alopecia 1/1/2009 61 Female 115 lb 10/26/2010 Consumer United States
Primary
Concomitant
Pruritus Other Serious 6/15/2010 72 Female 190 lb 10/27/2010 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization Female 10/27/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 10/27/2010 Consumer United States
Primary
Concomitant
Drug Effect Decreased 64 Male 10/28/2010 Consumer United States
Primary
Concomitant
Cataract Other Serious 61 Female 10/13/2010 Consumer United States
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 9/13/2010 78 Male 188 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 2/10/2004 60 Female 141 lb 11/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Ischaemia Other Serious 11/17/2007 75 Male 165 lb 11/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 68 Male 303 lb 11/4/2010 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 9/1/2010 11/4/2010 Physician Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/1/2010 74 Male 190 lb 11/8/2010 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 69 Male 11/11/2010 Lawyer United States
Primary
Concomitant
Poor Quality Drug Administered Hospitalization Male 11/11/2010 Physician United States
Primary
Concomitant
Pain In Extremity 60 Female 11/11/2010 Consumer United States
Primary
Secondary
Neuropathy Peripheral Other Serious 43 Female 11/15/2010 Consumer United States
Primary
Concomitant
Dyspepsia 7/1/2010 55 Male 11/16/2010 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 9/1/2010 11/19/2010 Other Health Professional Netherlands
Primary
Concomitant
Neuropathy Peripheral Other Serious 43 Female 11/19/2010 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 8/4/2010 72 Male 192 lb 10/12/2010 Netherlands
Primary
Concomitant
Oedema Peripheral Hospitalization Female 11/30/2010 Consumer United States
Primary
Concomitant
Thirst Death 12/15/2006 12/6/2010 Physician United States
Primary
Concomitant
Pain In Extremity 65 Female 195 lb 12/14/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia 82 Male 12/14/2010 Consumer United States
Primary
Concomitant
Vertebral Artery Occlusion Other Serious 66 Male 12/3/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 7/16/2010 60 Female 160 lb 11/10/2010 Consumer United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Tearfulness Hospitalization 12/16/2010 Female 12/29/2010 Consumer United States
Primary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Pneumonia Life Threatening Female 1/6/2011 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 11/29/2010 83 Male 1/7/2011 Consumer United States
Primary
Concomitant
Atrial Fibrillation Death 11/12/2007 74 Female 1/12/2011 Lawyer United States
Primary
Concomitant
Cholecystitis Other Serious 7/5/2006 36 Female 160 lb 1/14/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 7/5/2006 36 Female 160 lb 1/14/2011 Physician United States
Primary
Secondary
Concomitant
Cough 10/1/2010 71 Male 1/14/2011 Consumer
Primary
Concomitant
Loss Of Consciousness Other Serious 12/1/2010 71 Male 1/18/2011 Consumer United States
Primary
Concomitant
Urinary Tract Infection 12/1/2010 78 Female 1/18/2011 Consumer
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Apparent Death Other Serious Female 1/18/2011 Consumer United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 53 Male 1/26/2011 Physician China
Primary
Concomitant
Interacting
Pruritus Other Serious 1/1/2008 53 Male 293 lb 1/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/31/2010 65 Male 218 lb 1/27/2011 Physician Germany
Primary
Concomitant
Nausea 63 Female 174 lb 1/28/2011 Consumer United States
Primary
Secondary
Concomitant
Crohn's Disease Hospitalization 7/1/2009 51 Male 140 lb 1/28/2011 Consumer United States
Primary
Concomitant
Mouth Ulceration Other Serious 6/1/2009 50 Female 158 lb 1/29/2011 Consumer United States
Primary
Concomitant

Drug Data