Isosorbide Dinitrate combined with Lasix

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Fall Death 3/4/2006 78 Female 3/9/2006 Japan
Primary
Concomitant
Cerebrovascular Accident Other Serious 2/9/2004 75 Female 161 lb 3/21/2006 Lawyer United States
Primary
Concomitant
Sudden Cardiac Death Death 3/3/2006 78 Female 3/23/2006 Japan
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/1999 77 Male 231 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Sudden Death Death 3/3/2006 78 Female 4/13/2006 Japan
Primary
Concomitant
Staphylococcal Infection Other Serious 12/1/2004 77 5/11/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Death 3/29/2006 72 Male 4/28/2006 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 2/22/2006 Female 5/31/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 6/1/2006 83 Male 7/21/2006 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 8/4/2006 Physician United States
Primary
Concomitant
Pruritus Hospitalization 1/1/2005 Male 8/8/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Death 6/30/2005 79 Male 8/2/2006 Physician Japan
Primary
Secondary
Concomitant
Skin Exfoliation 4/15/2006 83 Male 7/12/2006 United States
Primary
Concomitant
Therapy Non-responder Hospitalization 1/1/2001 67 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2006 69 Male 150 lb 8/18/2006 United States
Primary
Concomitant
Primary Hypothyroidism Other Serious 54 Female 8/23/2006 Physician Japan
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 8/30/2006 Physician United States
Primary
Concomitant
Primary Hypothyroidism Other Serious 54 Female 9/6/2006 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/20/2006 70 Male 9/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2005 81 Male 247 lb 9/28/2006 Pharmacist United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 4/3/2005 85 Male 150 lb 9/28/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 4/20/2005 38 Female 101 lb 11/30/2006 Physician Japan
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/23/2006 65 Male 247 lb 10/21/2006 Pharmacist United States
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 1/25/2007 Physician Japan
Primary
Concomitant
Tachycardia Death 1/12/2007 72 Male 3/14/2007 Physician Japan
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced 2/9/2007 92 Female 141 lb 5/17/2007 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Vision Blurred 11/15/2006 Female 232 lb 6/26/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 7/1/2006 62 Male 163 lb 6/29/2007 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Death 4/24/2007 71 Female 6/29/2007 Japan
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 12/1/2006 64 Male 7/16/2007 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 2/10/2006 59 Female 7/11/2007 Pharmacist United States
Primary
Secondary
Concomitant
Depression Other Serious 4/25/2002 Female 7/17/2007 Lawyer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Myocardial Infarction Death 4/7/2007 67 Female 170 lb 7/24/2007 United States
Primary
Concomitant
Nausea 9/1/2006 Female 7/26/2007 Consumer United States
Primary
Concomitant
Weight Decreased 8/1/2006 Female 7/26/2007 Physician United States
Primary
Concomitant
Somnolence 3/21/2007 73 Male 7/10/2007 Consumer United States
Primary
Concomitant
Pain 78 Female 8/3/2007 Consumer United States
Primary
Concomitant
Muscle Haemorrhage Hospitalization 12/30/2006 Male 214 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 Female 8/27/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 67 Male 217 lb 9/11/2007 Consumer United States
Primary
Concomitant
Initial Insomnia 3/8/2007 65 Female 140 lb 8/13/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced 2/9/2007 92 Female 141 lb 8/16/2007 Other Health Professional United States
Primary
Concomitant
Yellow Skin Other Serious 4/5/2006 87 Male 1/31/2007 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious Male 9/20/2007
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 9/1/2006 82 Female 10/4/2007 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/29/2007 76 Female 10/17/2007 Consumer United States
Primary
Concomitant
Muscular Weakness 3/1/2006 76 Female 10/25/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2007 77 Male 10/25/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 5/1/2007 70 Male 154 lb 10/24/2007 Physician Japan
Primary
Secondary
Concomitant
Prostatic Specific Antigen Increased Male 11/13/2007 Consumer United States
Primary
Concomitant
Viral Infection 9/14/2006 66 Male 11/13/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/29/2007 Female 160 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Rash Life Threatening 10/16/2007 65 Male 11/20/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 4/29/2007 76 Female 11/15/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 301 lb 11/21/2007 Consumer United States
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 9/1/2006 82 Female 11/21/2007 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 9/1/2006 82 Female 12/3/2007 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 3/21/2007 54 Male 188 lb 12/5/2007 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 8/1/2000 81 Male 185 lb 12/6/2007 Consumer United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/20/2007 7 Male 12/4/2007 Physician Japan
Primary
Secondary
Concomitant
Vasoplegia Syndrome Death 7/21/2004 48 Male 217 lb 11/1/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/1992 36 Female 291 lb 12/17/2007 Consumer United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Breast Pain 2/1/2007 64 Male 12/20/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 9/6/2007 82 Female 10/17/2007 Other Health Professional United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/21/2007 7 Male 12/21/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2003 Female 200 lb 1/18/2008 Physician United States
Primary
Concomitant
Splenomegaly Other Serious 6/1/2007 Female 144 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/1/2003 Female 200 lb 1/25/2008 Physician United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Rash Other Serious 9/6/2007 82 Female 1/4/2008 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 6/7/2003 81 Female 2/14/2008 Physician Germany
Primary
Secondary
Scratch Hospitalization 3/6/2007 Male 220 lb 6/27/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 9/30/2002 Female 200 lb 2/29/2008 Other Health Professional United States
Primary
Concomitant
Stomach Discomfort Hospitalization 12/1/2007 Female 2/26/2008 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization Male 3/5/2008 Other Health Professional United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/6/2008 87 Female 3/13/2008 Consumer United States
Primary
Concomitant
Generalised Oedema Hospitalization 12/19/2007 81 Female 112 lb 3/11/2008 Other Health Professional Japan
Primary
Concomitant
Cardiac Failure Hospitalization 11/25/2007 Female 3/19/2008 Japan
Primary
Concomitant
Ascites Other Serious 9/1/2007 63 Female 233 lb 3/20/2008 Physician United States
Primary
Concomitant
Unevaluable Event Hospitalization 6/27/2007 Female 326 lb 3/31/2008 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Hospitalization 11/25/2007 Female 4/2/2008 Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal Other Serious 9/25/2007 80 Female 75 lb 4/10/2008 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 2/1/2008 58 Female 4/17/2008 United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 4/28/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1992 36 Female 291 lb 5/1/2008 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred 12/29/2007 74 Female 175 lb 3/14/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 66 Female 191 lb 5/8/2008 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 74 Male 5/17/2008 Consumer
Primary
Concomitant
Myocardial Infarction Hospitalization 3/20/2008 67 Male 165 lb 5/29/2008 United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/24/2007 80 Female 6/5/2008 United States
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/1/2008 73 Female 148 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 7/20/2007 52 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 5/1/2008 90 Male 161 lb 7/14/2008 Other Health Professional United States
Primary
Concomitant
Presyncope Other Serious 1/1/2000 Female 185 lb 7/15/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2007 47 Female 300 lb 7/22/2008 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/25/2008 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Rash 4/5/2008 62 Male 220 lb 8/1/2008 Consumer United States
Primary
Concomitant
Blue Toe Syndrome 2/2/2008 75 Male 7/29/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 4/15/2001 Female 200 lb 8/8/2008 Consumer United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/19/2007 7 Male 37 lb 9/11/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 11/25/2007 Female 9/22/2008
Primary
Concomitant
Weight Decreased Other Serious 7/17/2008 58 Male 210 lb 11/7/2008 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 10/19/2007 7 Male 37 lb 11/5/2008 Physician Japan
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 5/1/2008 68 Female 215 lb 12/8/2008 Consumer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 Male 241 lb 12/23/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 78 Female 197 lb 12/23/2008 Consumer United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 3/20/2008 80 Female 86 lb 12/24/2008 Physician Japan
Primary
Concomitant
Red Blood Cell Count Decreased Required Intervention 9/1/2007 Female 9/17/2008 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization Female 179 lb 1/9/2009 Consumer United States
Primary
Concomitant
Ventricular Arrhythmia Other Serious 6/20/2004 Male 150 lb 1/14/2009 Other Health Professional United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 1/20/2009 Consumer
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 12/24/2008 Female 179 lb 1/21/2009 Physician United States
Primary
Concomitant
Death Death Male 1/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Coronary Artery Stenosis Life Threatening 3/20/2008 80 Female 86 lb 2/5/2009 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 11/30/2008 77 Male 2/4/2009 Physician Japan
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 8/1/2008 Male 2/24/2009 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/11/2009 76 Female 3/27/2009 Japan
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 65 Female 160 lb 4/19/2009 United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 3/11/2009 76 Female 4/20/2009 Japan
Primary
Secondary
Concomitant
Potentiating Drug Interaction Other Serious 1/1/2009 64 Female 5/22/2009 Consumer United States
Primary
Concomitant
Mouth Haemorrhage Hospitalization 4/15/2009 Female 119 lb 6/17/2009 Physician Japan
Primary
Concomitant
Interacting
Urinary Tract Infection Enterococcal Other Serious 5/2/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Hospitalization 4/15/2009 Female 119 lb 7/6/2009 Physician Japan
Primary
Concomitant
Interacting
Weight Decreased Other Serious 76 Male 7/15/2009 Lawyer United States
Primary
Concomitant
Vomiting Death 81 Female 7/14/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 10/25/2007 73 Female 229 lb 7/17/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 70 Male 7/21/2009 Lawyer United States
Primary
Concomitant
Oedema Hospitalization 63 Female 7/21/2009 Lawyer United States
Primary
Concomitant
Sinus Disorder Life Threatening 2/1/2008 Female 7/29/2009 Physician
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 7/22/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 10/1/2008 89 Male 168 lb 7/22/2009 Consumer United States
Primary
Concomitant

Drug Data