Isosorbide Dinitrate combined with Lantus

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hypertensive Crisis Hospitalization 12/30/2005 44 Female 194 lb 3/24/2006 Physician Germany
Primary
Concomitant
Syncope Hospitalization 3/1/2006 80 Male 6/5/2006 Other Health Professional
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 3/1/2006 80 Male 6/8/2006 Other Health Professional
Primary
Secondary
Concomitant
Dizziness 2/14/2006 66 Male 218 lb 4/17/2006 United States
Primary
Concomitant
Rash Pruritic Other Serious 3/1/2005 75 Male 194 lb 8/1/2006 Consumer United States
Primary
Concomitant
Skin Exfoliation 4/1/2006 Female 160 lb 8/8/2006 Consumer United States
Primary
Concomitant
Pruritus Hospitalization 1/1/2005 Male 8/8/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization Female 183 lb 9/6/2006 Consumer United States
Primary
Secondary
Concomitant
Thirst 63 Male 355 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Inadequate Diet Required Intervention 10/5/2005 73 Male 1/3/2007 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 4/16/2007 67 Male 5/22/2007 Physician United States
Primary
Secondary
Concomitant
Walking Aid User Other Serious 12/12/2006 51 Female 140 lb 6/13/2007 Physician United States
Primary
Concomitant
Weight Decreased 2/1/2007 66 Female 294 lb 4/10/2007 Consumer United States
Primary
Concomitant
Paraesthesia 66 Male 224 lb 4/10/2007 Consumer United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 9/13/2006 73 Female 179 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Malaise Other Serious 3/1/2006 45 Male 4/26/2007 Physician United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2006 47 Female 4/26/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 9/1/2005 80 Male 4/26/2007 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 7/18/2007 60 Male 179 lb 7/19/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 7/1/2007 59 Male 8/16/2007 Consumer United Kingdom
Primary
Concomitant
Weight Decreased 1/1/2006 66 Female 294 lb 7/11/2007 Consumer United States
Primary
Concomitant
Syncope Hospitalization 8/28/2007 Male 9/4/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2006 67 Male 230 lb 8/24/2007 Consumer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 1/1/2004 Male 9/6/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 5/10/2007 60 Female 7/26/2007 United States
Primary
Secondary
Concomitant
Paraesthesia Oral Hospitalization 8/8/2007 Female 10/11/2007 Consumer United States
Primary
Concomitant
Nocturnal Dyspnoea 8/22/2007 69 Male 11/14/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 5/10/2007 60 Female 10/22/2007 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 11/23/2006 66 Male 230 lb 11/30/2007 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 9/12/2007 Female 175 lb 12/14/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 12/15/2007 58 Male 203 lb 1/28/2008 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 199 lb 1/21/2008 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 3/14/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 180 lb 4/22/2008 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 4/30/2008 Consumer United Kingdom
Primary
Concomitant
Hunger 1/1/2008 Male 224 lb 3/14/2008 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2008 Male 224 lb 3/14/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/12/2007 82 Male 192 lb 5/22/2008 Physician Germany
Primary
Concomitant
Renal Failure Acute Other Serious 10/1/2006 54 Female 5/20/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 Female 6/4/2008 Lawyer United States
Primary
Secondary
Concomitant
Headache 10/12/2007 74 Male 290 lb 6/19/2008 Consumer United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Female 202 lb 6/23/2008 Consumer United States
Primary
Concomitant
Hyperglycaemia Other Serious 7/20/2007 52 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 10/2/2007 87 Male 4/30/2008 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2004 63 Male 7/14/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 Female 202 lb 7/19/2008 Consumer United States
Primary
Concomitant
Renal Disorder Hospitalization 12/1/2007 73 Female 7/29/2008 Consumer United Kingdom
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 6/16/2008 75 Male 8/6/2008 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2004 63 Male 8/12/2008 Consumer United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 12/1/2007 Male 8/12/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/1/2004 63 Male 11/13/2008 Consumer United States
Primary
Concomitant
Pneumonia Death 8/1/2008 Female 201 lb 12/24/2008 Physician United States
Primary
Concomitant
Red Blood Cell Count Decreased Required Intervention 9/1/2007 Female 9/17/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Other Serious Female 1/17/2009 Physician United States
Primary
Concomitant
Nausea Other Serious 1/1/2007 Male 232 lb 1/29/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 59 Female 7/19/2009 United States
Primary
Concomitant
Oedema Hospitalization 63 Female 7/21/2009 Lawyer United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 7/23/2003 49 Female 191 lb 7/30/2009 United States
Primary
Concomitant
Weight Decreased 1/1/2009 54 Male 144 lb 7/22/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/13/2009 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 9/7/2008 53 Male 243 lb 8/12/2009 United States
Primary
Concomitant
Speech Disorder Hospitalization 50 Male 8/14/2009 United States
Primary
Concomitant
Pruritus Female 8/22/2009 United States
Primary
Concomitant
Hyperhidrosis Female 8/22/2009 United States
Primary
Concomitant
Flushing Female 186 lb 8/22/2009 United States
Primary
Concomitant
Blood Glucose Increased 6/1/2009 Female 8/23/2009 United States
Primary
Concomitant
Flushing 8/1/2008 Male 265 lb 8/24/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 180 lb 8/21/2009 Lawyer United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 8/19/2009 Female 245 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 Male 290 lb 9/24/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2000 Male 290 lb 10/13/2009 Consumer United States
Primary
Secondary
Concomitant
Retinopathy Disability 10/21/2009 Male 203 lb 11/20/2009 Physician Germany
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2007 Male 1/7/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2009 55 Male 196 lb 2/26/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 73 Female 3/25/2010 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization Female 154 lb 4/22/2010 Physician United States
Primary
Concomitant
Myocardial Ischaemia Other Serious Male 222 lb 5/10/2010 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 78 Male 222 lb 5/19/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/19/2007 64 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Macular Degeneration Other Serious 1/1/2006 82 Female 170 lb 6/9/2010 Consumer United States
Primary
Secondary
Concomitant
Diarrhoea 8/6/2009 63 Female 337 lb 6/29/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2009 55 Male 240 lb 7/7/2010 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 84 Male 7/8/2010 Lawyer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 4/1/2008 61 Male 196 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 8/23/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 84 Male 9/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/26/2007 50 Female 265 lb 10/22/2010 Other Health Professional United States
Primary
Concomitant
Oral Mucosal Exfoliation Female 11/2/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 69 Male 11/11/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 2/1/2008 84 Male 165 lb 11/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Thirst Death 12/15/2006 12/6/2010 Physician United States
Primary
Concomitant
Pneumonia Life Threatening Female 1/6/2011 Consumer United States
Primary
Concomitant
Lip Swelling 12/1/2010 81 Male 1/10/2011 Consumer
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 72 Female 1/13/2011 Consumer United States
Primary
Concomitant
Apparent Death Other Serious Female 1/18/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Death 12/1/2007 70 Male 1/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Disorder Other Serious 11/19/2007 64 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Cough 6/1/2010 68 Female 199 lb 1/29/2011 Other Health Professional United States
Primary
Concomitant
Injection Site Haematoma 73 Female 1/30/2011 Consumer United States
Primary
Concomitant
Dizziness 73 Female 1/30/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Hospitalization 1/22/2011 52 Male 2/3/2011 Other Health Professional Philippines
Primary
Secondary
Concomitant
Erythema Other Serious 12/26/2007 50 Female 265 lb 2/3/2011 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Pain Other Serious Female 168 lb 2/7/2011 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2010 56 Male 185 lb 2/21/2011 Consumer United States
Primary
Concomitant
Limb Injury Other Serious Female 168 lb 2/18/2011 Consumer United States
Primary
Concomitant
Malaise Life Threatening Female 168 lb 2/25/2011 Physician United States
Primary
Concomitant
General Physical Health Deterioration Death 1/25/2010 Male 157 lb 3/14/2011 Physician Germany
Primary
Concomitant
Nausea Hospitalization 11/30/2010 74 Male 127 lb 3/17/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 10/2/2005 52 Female 220 lb 3/23/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 10/2/2005 52 Female 220 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Blood Glucose Increased 2/20/2011 75 Male 3/25/2011 Consumer United States
Primary
Concomitant
Confusional State 1/24/2011 54 Female 3/25/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 1/25/2010 86 Male 157 lb 3/29/2011 Physician Germany
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2011 59 Male 3/31/2011 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Hospitalization 2/20/2008 48 Female 180 lb 3/17/2011 United States
Primary
Concomitant
Movement Disorder Hospitalization Female 168 lb 4/6/2011 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 11/30/2010 74 Male 127 lb 4/19/2011 Consumer United States
Primary
Concomitant
Productive Cough Hospitalization Female 168 lb 4/18/2011 Consumer United States
Primary
Concomitant
Biopsy Heart Hospitalization 1/1/2007 54 Male 4/29/2011 Other Health Professional United States
Primary
Concomitant
Blood Glucose Increased Male 5/10/2011 Consumer United States
Primary
Concomitant
Bronchitis Hospitalization 72 Female 215 lb 4/27/2011 Consumer United States
Primary
Concomitant
Pruritus Hospitalization 4/20/2011 44 Male 249 lb 5/16/2011 Pharmacist United States
Primary
Concomitant
Generalised Erythema Other Serious 1/1/2008 52 Male 5/18/2011 Consumer United States
Primary
Concomitant
Hyperlipidaemia Other Serious 1/1/2007 54 Male 6/2/2011 Physician United States
Primary
Concomitant
Hypophagia Hospitalization 3/29/2010 76 Male 93 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Death Other Serious 9/8/2006 63 Female 166 lb 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 72 Female 172 lb 7/26/2011 Consumer United States
Primary
Secondary
Concomitant
Flushing Male 215 lb 8/5/2011 Consumer United States
Primary
Concomitant
Flushing 6/1/2010 50 Female 297 lb 8/5/2011 Consumer United States
Primary
Concomitant
Flushing Male 8/6/2011 Consumer United States
Primary
Concomitant
Nervousness Other Serious Female 208 lb 8/10/2011 Other Health Professional United States
Primary
Concomitant
Urticaria Hospitalization 3/4/2009 60 Female 216 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Pain Other Serious Female 208 lb 8/15/2011 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 7/1/2011 72 Female 172 lb 8/23/2011 Consumer United States
Primary
Secondary
Concomitant
Confusional State 8/12/2011 Female 9/6/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 10/2/2005 52 Female 220 lb 9/15/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Disability 1/1/2006 62 Female 204 lb 8/2/2011 Physician United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 8/12/2011 83 Female 152 lb 9/30/2011 Physician United States
Primary
Concomitant
Hernia Other Serious 7/1/2011 74 Male 174 lb 10/4/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Eye Disorder Hospitalization Male 10/13/2011 Consumer United States
Primary
Concomitant
Death Death 10/12/2011 70 Male 10/19/2011 Other Health Professional United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 6/1/2011 52 Female 312 lb 10/6/2011 Physician United States
Primary
Concomitant
Dehydration Hospitalization 9/30/2011 60 Female 11/1/2011 Consumer United States
Primary
Secondary
Concomitant
Eye Disorder Hospitalization 4/28/2011 81 Male 11/22/2011 Consumer United States
Primary
Concomitant
Faecal Incontinence Hospitalization 4/1/2011 65 Female 217 lb 11/23/2011 Physician United States
Primary
Concomitant
Malaise Other Serious 68 Female 11/28/2011 Consumer United States
Primary
Secondary
Concomitant

Drug Data