Isosorbide Dinitrate combined with Lansoprazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder Hospitalization 2/23/2005 64 Male 1/31/2006 Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 12/15/2005 63 Female 2/8/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/16/2006 63 Male 164 lb 5/25/2006 Pharmacist United States
Primary
Concomitant
Stomach Discomfort Hospitalization 1/1/2005 87 Male 134 lb 5/31/2006 United States
Primary
Concomitant
Pruritus Other Serious 8/25/2006 69 Male 10/20/2006 Physician Japan
Primary
Secondary
Concomitant
Pruritus Other Serious 8/25/2006 69 Male 10/27/2006 Physician Japan
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
Shock Life Threatening 2/8/2007 3/5/2007 Japan
Primary
Concomitant
Syncope Hospitalization 6/16/2004 82 Male 3/7/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Life Threatening 2/8/2007 73 Female 101 lb 7/3/2007 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/1/2007 70 Male 154 lb 7/13/2007 Physician Japan
Primary
Secondary
Concomitant
Restlessness 4/3/2007 71 Male 8/17/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 6/10/2007 Male 9/11/2007 Physician United States
Primary
Secondary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 10/1/2007 69 Female 11/9/2007 Consumer United Kingdom
Primary
Concomitant
Xanthopsia Other Serious 62 Male 1/28/2008 Physician Japan
Primary
Concomitant
Crohn's Disease 2/1/2008 Female 130 lb 3/15/2008 Consumer United States
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/8/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 4/22/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 5/1/2008 Physician Japan
Primary
Concomitant
Shock Other Serious 2/1/2008 Male 7/3/2008 Physician Japan
Primary
Concomitant
Pseudomembranous Colitis Other Serious 7/28/2008 94 Female 8/14/2008 Pharmacist Japan
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 9/30/2008 60 Male 12/26/2008 Other Health Professional France
Primary
Concomitant
Oedema Hospitalization 12/7/2008 83 Female 117 lb 12/26/2008 Consumer Germany
Primary
Concomitant
Skin Burning Sensation 1/1/2004 Female 192 lb 1/15/2009 Physician United States
Primary
Concomitant
Oropharyngeal Pain Other Serious 81 Female 1/29/2009 Consumer United Kingdom
Primary
Secondary
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 3/9/2009 Other Health Professional France
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/7/2008 83 Female 117 lb 3/13/2009 Other Health Professional Germany
Primary
Concomitant
Hypokalaemia Hospitalization 4/22/2007 71 Female 107 lb 4/3/2009 Japan
Primary
Concomitant
Dysuria 3/23/2009 83 Female 4/20/2009 Japan
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 1/29/2009 76 Male 4/17/2009 Pharmacist United States
Primary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 6/24/2009 Other Health Professional France
Primary
Secondary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization 9/30/2008 60 Male 6/26/2009 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/4/2009 54 Female 7/16/2009 United Kingdom
Primary
Concomitant
Temperature Difference Of Extremities Hospitalization 54 Female 8/5/2009 United States
Primary
Concomitant
Skin Ulcer Life Threatening 72 Male 9/30/2009 United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 7/4/2009 Male 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 8/19/2009 Female 88 lb 12/8/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 1/4/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/29/2009 80 Female 2/15/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/29/2009 80 Female 2/17/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 8/19/2009 81 Female 88 lb 2/18/2010 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 12/29/2009 80 Female 2/22/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 3/3/2010 Other Health Professional Norway
Primary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 3/3/2010 Other Health Professional Norway
Primary
Concomitant
Hypoglycaemia Hospitalization 12/29/2009 80 Female 3/29/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 1/20/2010 83 Female 88 lb 3/31/2010 Physician Japan
Primary
Secondary
Concomitant
Alopecia Other Serious 1/27/2010 70 Female 192 lb 3/31/2010 Physician United Kingdom
Primary
Concomitant
Somnolence Hospitalization 12/29/2009 80 Female 4/5/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/17/2010 79 Female 161 lb 4/12/2010 Other Health Professional United States
Primary
Concomitant
Ileus Other Serious 4/1/2010 68 Male 4/8/2010 Other Health Professional Japan
Primary
Concomitant
Death Death 9/1/2010 39 Male 128 lb 10/8/2010 Consumer Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 9/27/2010 39 Male 128 lb 10/19/2010 Consumer Japan
Primary
Concomitant
Rectal Cancer Recurrent Other Serious 10/27/2010 67 Male 123 lb 11/3/2010 Physician Japan
Primary
Concomitant
Rectal Cancer Other Serious 10/27/2010 Male 123 lb 12/7/2010 Physician Japan
Primary
Concomitant
Tongue Coated Hospitalization 75 Female 123 lb 12/15/2010 Other Health Professional Japan
Primary
Concomitant
Cardio-respiratory Arrest Death 9/27/2010 39 Male 128 lb 12/16/2010 Consumer Japan
Primary
Concomitant
Pseudomembranous Colitis Death 7/4/2003 84 Female 162 lb 1/24/2011 Physician United States
Primary
Secondary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 11/21/2010 62 Female 1/25/2011 Other Health Professional United States
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 11/21/2010 62 Female 2/3/2011 Other Health Professional United States
Primary
Concomitant
Escherichia Urinary Tract Infection Hospitalization 11/21/2010 62 Female 2/28/2011 Physician United States
Primary
Concomitant
Gastrooesophageal Reflux Disease 1/26/2011 64 Female 3/10/2011 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 11/21/2010 62 Female 3/15/2011 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 1/2/2011 71 Male 132 lb 3/30/2011 Physician United States
Primary
Concomitant
Interacting
Post Procedural Haemorrhage Hospitalization 1/2/2011 71 Male 132 lb 3/29/2011 Physician United States
Primary
Concomitant
Interacting
Erythema Disability 5/11/2006 69 Male 202 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 1/2/2011 71 Male 132 lb 4/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Anal Fistula Hospitalization 1/2/2011 71 Male 132 lb 4/28/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Unevaluable Event 11/27/2010 73 Male 163 lb 2/7/2011 Consumer United States
Primary
Concomitant
Pancytopenia Other Serious 11/16/2010 69 Female 112 lb 5/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/16/2010 69 Female 112 lb 5/27/2011 Physician Japan
Primary
Secondary
Concomitant
Abdominal Mass Hospitalization 1/2/2011 78 Female 6/2/2011 Pharmacist Canada
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 6/2/2011 Pharmacist Japan
Primary
Concomitant
Pancytopenia Other Serious 11/16/2010 69 Female 112 lb 6/2/2011 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Death 5/29/2010 57 Male 6/3/2011 Physician Japan
Primary
Concomitant
Pancytopenia Other Serious 11/16/2010 69 Female 112 lb 6/6/2011 Physician Japan
Primary
Secondary
Concomitant
Dyspnoea Other Serious 12/16/2004 57 Male 6/4/2011 Physician Japan
Primary
Concomitant
Death Death 6/1/2008 72 Female 84 lb 6/4/2011 Other Health Professional Japan
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 6/9/2011 Pharmacist Japan
Primary
Concomitant
General Physical Health Deterioration Life Threatening 11/8/2010 84 Male 119 lb 6/16/2011 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 5/16/2011 67 Male 134 lb 6/8/2011 Physician Japan
Primary
Concomitant
Visual Impairment Other Serious Female 6/22/2011 Pharmacist Japan
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 141 lb 6/27/2011 Pharmacist Japan
Primary
Concomitant
Blood Pressure Diastolic Decreased Death 4/12/2011 69 Male 104 lb 6/30/2011 Physician Japan
Primary
Concomitant
Hypoglycaemia Other Serious 5/12/2011 87 Male 7/1/2011 Pharmacist Japan
Primary
Concomitant
Oesophageal Candidiasis Other Serious 5/23/2011 68 Female 141 lb 7/6/2011 Physician Japan
Primary
Concomitant
Blood Pressure Diastolic Decreased Death 4/12/2011 69 Male 104 lb 7/13/2011 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2011 Male 7/15/2011 Physician Japan
Primary
Secondary
Concomitant
Vision Blurred 6/10/2011 82 Female 7/19/2011 Pharmacist Japan
Primary
Concomitant
Fear Death Male 7/27/2011 Lawyer United States
Primary
Concomitant
Condition Aggravated Death 79 Female 7/29/2011 Physician Japan
Primary
Concomitant
Terminal Insomnia Male 240 lb 8/5/2011 Consumer United States
Primary
Concomitant
Acute Myocardial Infarction Life Threatening 3/17/2011 61 Male 8/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Other Serious 5/16/2011 67 Male 134 lb 8/4/2011 Physician Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2011 76 Male 8/16/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 8/2/2011 72 Female 8/23/2011 Other Health Professional Japan
Primary
Concomitant
Agranulocytosis Hospitalization 7/7/2011 76 Male 8/23/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 7/1/2011 76 Female 8/24/2011 Physician Japan
Primary
Concomitant
Blood Uric Acid Increased Other Serious 7/29/2010 77 Female 110 lb 8/30/2011 Physician Japan
Primary
Concomitant
Pulmonary Mass Hospitalization 3/3/2011 68 Male 8/31/2011 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 2/28/2011 80 Male 121 lb 9/2/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 9/12/2011 Physician Japan
Primary
Secondary
Concomitant
Platelet Count Decreased Life Threatening 6/5/2011 76 Female 9/12/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Other Serious 6/5/2011 76 Female 9/19/2011 Physician Japan
Primary
Concomitant
Haemorrhage Subcutaneous Other Serious 5/26/2011 83 Male 110 lb 9/19/2011 Physician Japan
Primary
Concomitant
Device Related Infection Hospitalization 8/21/2011 78 Male 104 lb 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Oral Discomfort Hospitalization 8/30/2011 82 Male 137 lb 9/20/2011 Pharmacist Japan
Primary
Concomitant
Diabetes Mellitus Inadequate Control Other Serious 1/1/2000 40 Female 118 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 9/3/2011 70 Male 9/23/2011 Consumer Switzerland
Primary
Concomitant
Neutropenic Infection Other Serious 5/20/2009 49 Male 150 lb 9/26/2011 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/21/2011 78 Male 104 lb 9/30/2011 Physician Japan
Primary
Secondary
Concomitant
Thirst Hospitalization 8/30/2011 82 Male 137 lb 10/4/2011 Pharmacist Japan
Primary
Concomitant
Pleural Effusion Hospitalization 8/21/2011 78 Male 104 lb 10/12/2011 Consumer Japan
Primary
Secondary
Concomitant
Cerebral Disorder Hospitalization 9/1/2004 62 Male 170 lb 10/5/2011 Lawyer United States
Primary
Concomitant
Hypocoagulable State Other Serious 5/23/2011 83 Male 110 lb 10/18/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Disorder Hospitalization 5/23/2009 60 82 lb 10/25/2011 Pharmacist Japan
Primary
Concomitant
Pulmonary Oedema Death 10/21/2010 65 Male 128 lb 10/27/2011 Physician Japan
Primary
Concomitant
Cardiac Failure Death 73 Female 11/1/2011 Consumer Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization Female 10/31/2011 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/3/2011 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 7/13/2010 92 Female 99 lb 11/3/2011 Physician Japan
Primary
Concomitant
Blood Potassium Increased Other Serious 7/13/2010 92 Female 99 lb 11/8/2011 Physician Japan
Primary
Concomitant
Acute Myocardial Infarction Death 11/4/2011 72 Male 11/10/2011 Physician Japan
Primary
Secondary
Concomitant
Acute Respiratory Failure Death 9/10/2011 85 Female 11/13/2011 Other Health Professional France
Primary
Concomitant
Pancytopenia Other Serious 11/16/2010 69 Female 112 lb 11/14/2011 Physician Japan
Primary
Secondary
Concomitant
Hypopharyngeal Cancer Death 4/13/2011 59 Male 120 lb 11/22/2011 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 5/23/2009 60 Female 82 lb 11/23/2011 Physician Japan
Primary
Concomitant
Gout Other Serious 5/11/2006 69 Male 202 lb 11/24/2011 Other Health Professional United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/31/2011 77 Female 110 lb 11/28/2011 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/1/2011 77 Male 225 lb 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Acute Myocardial Infarction Hospitalization 11/26/2011 51 Male 176 lb 12/9/2011 Physician Japan
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 11/1/2011 77 Male 225 lb 12/12/2011 Physician United States
Primary
Secondary
Concomitant
Death Hospitalization 11/10/2011 77 Male 225 lb 12/22/2011 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 8/1/2011 80 Male 12/28/2011 Consumer Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 12/27/2011 65 Male 1/6/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Hospitalization 10/20/2010 83 Male 1/11/2012 Physician Japan
Primary
Secondary
Concomitant
Peripheral Sensory Neuropathy Death 11/10/2011 77 Male 225 lb 1/13/2012 Physician United States
Primary
Secondary
Concomitant
Fall Hospitalization 11/1/2011 91 Male 1/12/2012 Physician United Kingdom
Primary
Concomitant
Hypokalaemia Hospitalization 7/14/2011 78 Male 132 lb 1/20/2012 Pharmacist Japan
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 12/27/2011 65 Male 1/23/2012 Physician Japan
Primary
Secondary
Concomitant
Altered State Of Consciousness Life Threatening 11/21/2011 86 106 lb 2/1/2012 Physician Japan
Primary
Concomitant
Neuropathy Peripheral Death 77 Male 2/2/2012 Consumer United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Death 11/1/2011 91 Male 2/3/2012 Consumer United Kingdom
Primary
Concomitant
Ventricular Fibrillation Other Serious 12/2/2011 77 Male 84 lb 2/7/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Other Serious 12/7/2011 70 Female 121 lb 2/8/2012 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Death 1/1/2011 77 Female 115 lb 2/9/2012 Physician Japan
Primary
Concomitant
Angina Pectoris Death 9/25/2009 59 Male 120 lb 2/15/2012 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 12/25/2011 77 Female 115 lb 2/16/2012 Physician Japan
Primary
Concomitant

Drug Data