Isoniazid combined with Levofloxacin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Shock Other Serious 6/1/2003 70 Male 2/1/2006 Physician Japan
Primary
Concomitant
Productive Cough Disability 10/26/2005 42 Female 120 lb 1/25/2006 United States
Primary
Secondary
Concomitant
Dermatitis Exfoliative Other Serious 90 Male 4/27/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 2/1/2003 66 Male 4/27/2006 Physician Japan
Primary
Concomitant
Dermatitis Exfoliative Other Serious 90 Male 4/27/2006 Physician Japan
Primary
Secondary
Vomiting Hospitalization 31 Male 99 lb 5/20/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 6/9/2006 Other Health Professional Hungary
Primary
Concomitant
Tuberculosis Life Threatening 1/1/2003 39 Male 8/22/2006 Spain
Primary
Secondary
Concomitant
Urine Abnormality Hospitalization 1/10/2006 27 Male 10/6/2006 Other Health Professional Hungary
Primary
Concomitant
Wheezing Required Intervention 9/5/2006 76 Female 10/6/2006 Physician Spain
Primary
Secondary
Concomitant
Wheezing Required Intervention 9/5/2006 76 Female 10/20/2006 Physician Spain
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 1/10/2006 27 Male 11/20/2006 Other Health Professional Hungary
Primary
Concomitant
Renal Failure Acute Death 6/17/2005 Male 12/13/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Death 6/17/2005 Male 2/15/2007 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/18/2005 58 Male 3/21/2007 Other Health Professional Japan
Primary
Concomitant
Hepatitis Fulminant Other Serious 10/5/2006 56 Female 4/9/2007 Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/18/2005 58 Male 4/26/2007 Other Health Professional Japan
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/23/2007 64 Male 6/8/2007 Consumer Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 4/1/2006 71 Female 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 5/23/2007 64 Male 117 lb 7/3/2007 Consumer Japan
Primary
Concomitant
Nephrotic Syndrome Other Serious 4/1/2006 71 Female 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 7/9/2007 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 4/1/2006 77 Female 7/11/2007 Physician Japan
Primary
Secondary
Concomitant
Atelectasis Other Serious 9/1/2005 76 Male 8/9/2007 Japan
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 8/22/2007 United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 9/1/2005 76 Male 8/21/2007 Japan
Primary
Secondary
Concomitant
Urinary Retention Other Serious 1/1/2005 78 Male 9/4/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 9/18/2007 United States
Primary
Secondary
Concomitant
Autoimmune Hepatitis Death 70 Female 10/22/2007 Other Health Professional Japan
Primary
Secondary
Autoimmune Hepatitis Death 70 Female 10/23/2007 Japan
Primary
Secondary
Pulmonary Tuberculosis Hospitalization 6/9/2007 27 Female 60 lb 11/26/2007 United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Hospitalization 9/20/2007 Female 132 lb 1/17/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 10/31/2007 83 Female 4/29/2008 Other Health Professional Japan
Primary
Concomitant
Quadriplegia Other Serious 2/1/2008 68 Female 5/9/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 5/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Hospitalization 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Oesophagitis Other Serious 81 Female 9/10/2008 Physician Italy
Primary
Secondary
Concomitant
Tuberculosis Other Serious 21 Male 12/16/2008
Primary
Secondary
Concomitant
Tuberculosis Other Serious Male 1/5/2009 Consumer Japan
Primary
Secondary
Concomitant
Renal Failure Death 51 Male 12/30/2008 Physician Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 9/18/2008 Male 187 lb 1/14/2009 Physician Portugal
Primary
Concomitant
Hepatitis Fulminant Death 1/22/2009 70 Male 2/26/2009 Physician Japan
Primary
Concomitant
Urinary Tract Infection Life Threatening 10/29/2002 Female 3/9/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 3/2/2009 Male 120 lb 3/13/2009 Physician India
Primary
Concomitant
Vesicoureteric Reflux Hospitalization 3/2/2004 Female 4/2/2009 Physician Turkey
Primary
Concomitant
Pancytopenia Hospitalization 65 Male 4/7/2009 Greece
Primary
Concomitant
Malaise Hospitalization 7/5/2008 77 Male 5/20/2009 Other Health Professional Japan
Primary
Concomitant
Urticaria Hospitalization 4/22/2008 76 Male 6/3/2009 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/8/2004 Male 176 lb 6/23/2009 Physician Spain
Primary
Secondary
Concomitant
Hypoglycaemia Death 1/22/2009 70 Male 6/22/2009 Physician Japan
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/9/2004 Male 7/2/2009 Physician Spain
Primary
Secondary
Concomitant
Lupus Nephritis Hospitalization 29 Male 7/21/2009 Physician Romania
Primary
Secondary
Concomitant
Lupus Nephritis Hospitalization 29 Male 7/24/2009 Physician Romania
Primary
Secondary
Concomitant
Lupus Nephritis Hospitalization 29 Male 8/3/2009 Physician Romania
Primary
Secondary
Concomitant
Thrombotic Microangiopathy Hospitalization 1/8/2004 70 Male 7/29/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Tuberculosis Death 24 Female 8/13/2009 Other Health Professional India
Primary
Secondary
Immune Reconstitution Syndrome Death 54 Male 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 6/1/2006 26 Male 118 lb 9/21/2009 Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 3/17/1994 41 Female 4/21/2010 Physician Japan
Primary
Secondary
Concomitant
Cerebral Infarction Other Serious 8/25/2009 79 Male 5/4/2010 Physician Japan
Primary
Concomitant
Sinus Tachycardia Hospitalization 6/1/2009 87 Female 6/30/2010 Physician Japan
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 6/1/2009 87 Female 7/2/2010 Physician Japan
Primary
Secondary
Concomitant
Tinea Infection Hospitalization 5/13/2010 59 Female 6/25/2010 Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 5/13/2010 59 Female 7/13/2010 Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 5/13/2010 59 Female 7/20/2010 Japan
Primary
Concomitant
Staphylococcus Test Positive Hospitalization 5/13/2010 59 Female 8/6/2010 Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 5/13/2010 59 Female 163 lb 8/27/2010 Japan
Primary
Concomitant
Tinnitus Other Serious 40 Female 10/22/2010 Physician India
Primary
Secondary
Concomitant
Cataract Hospitalization 5/19/2010 56 Female 3/28/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Fungal Infection Other Serious 10/13/2009 36 Male 143 lb 4/27/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 4/30/2008 79 Male 181 lb 4/19/2011 Other Health Professional Japan
Primary
Concomitant
Pneumonia Other Serious 7/23/2009 86 Male 6/2/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/12/2011 62 Female 150 lb 6/14/2011 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Hospitalization 5/12/2011 62 Female 150 lb 6/15/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 3/14/2011 61 Female 95 lb 6/30/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Septic Shock Death 10/12/2005 35 Male 207 lb 6/30/2011 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 7/23/2009 86 Male 7/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Enteritis Infectious Hospitalization 5/12/2011 62 Female 150 lb 7/13/2011 Physician Japan
Primary
Secondary
Concomitant
Blood Potassium Decreased Other Serious 7/23/2007 52 Male 161 lb 7/21/2011 Physician Japan
Primary
Concomitant
Discomfort Death 7/19/2011 60 Male 7/21/2011 Consumer United States
Primary
Concomitant
Interacting
Cytomegalovirus Infection Other Serious 6/18/2010 39 Female 110 lb 7/22/2011 Physician Japan
Primary
Secondary
Concomitant
Delirium Other Serious 6/22/2010 52 Female 7/25/2011 Physician China
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 3/22/2011 61 Female 95 lb 7/26/2011 Physician United States
Primary
Secondary
Concomitant
Headache Death 2/19/2009 23 Female 7/27/2011 Consumer Japan
Primary
Concomitant
Hepatotoxicity Other Serious 3/14/2011 61 Female 95 lb 7/28/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Drug Resistance Other Serious 7/1/2000 19 Female 7/22/2011 Other Health Professional Sweden
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/19/2009 23 Female 8/2/2011 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 5/6/2011 76 Female 8/4/2011 Other Health Professional Japan
Primary
Concomitant
Drug Ineffective For Unapproved Indication Other Serious 1/1/2008 47 Female 98 lb 8/3/2011 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 3/1/2010 70 Female 86 lb 8/10/2011 Pharmacist Japan
Primary
Secondary
Concomitant
Confusional State Other Serious 6/22/2010 52 Female 8/10/2011 Physician China
Primary
Concomitant
Epstein-barr Virus Infection Other Serious 1/1/2008 47 Female 98 lb 8/11/2011 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 8/12/2011 Other Health Professional United States
Primary
Secondary
Gastrointestinal Amyloidosis Hospitalization 7/25/2010 71 Female 84 lb 8/15/2011 Physician Japan
Primary
Secondary
Concomitant
Meningitis Tuberculous Hospitalization 5/6/2011 52 Male 8/16/2011 Physician France
Primary
Secondary
Concomitant
Rash Hospitalization 86 Male 106 lb 9/9/2011 Other Health Professional Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 5/30/2011 40 Male 9/13/2011 Physician France
Primary
Secondary
Concomitant
C-reactive Protein Increased Death 1/18/2006 35 Male 110 lb 9/20/2011 Physician Japan
Primary
Secondary
Concomitant
Infection Other Serious 1/1/2011 67 Male 110 lb 9/21/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatotoxicity Other Serious 3/14/2011 61 Female 95 lb 9/27/2011 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Death Male 10/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 80 Male 10/11/2011 Other Health Professional Japan
Primary
Secondary
Dyspnoea Other Serious 17 Male 10/12/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Liver Disorder Other Serious 70 Male 10/18/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Infection Death 1/1/2011 67 Male 110 lb 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 80 Male 10/20/2011 Other Health Professional Japan
Primary
Secondary
Renal Disorder Other Serious 90 Male 10/24/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Lung Neoplasm Hospitalization 7/23/2009 86 Male 10/27/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Liver Disorder Death Male 10/31/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 3/14/2011 61 Female 95 lb 11/3/2011 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/13/2009 36 Male 143 lb 11/7/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 10/8/2010 78 Male 11/11/2011 Consumer Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 10/8/2010 78 Male 11/16/2011 Consumer Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/1/2010 70 Female 86 lb 12/8/2011 Japan
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 5 Female 12/9/2011 Physician Greece
Primary
Secondary
Cerebral Aspergillosis Hospitalization 9/1/2011 5 Female 12/6/2011 Other Health Professional Greece
Primary
Concomitant
Aspergillosis Other Serious 12/16/2011 Greece
Primary
Concomitant
Liver Disorder Other Serious 6/14/2010 71 Male 12/23/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Pleural Effusion Death 3/1/2010 70 Female 86 lb 1/2/2012 Physician Japan
Primary
Secondary
Concomitant
Immunosuppression Hospitalization 1/17/2012 Greece
Primary
Concomitant
Liver Disorder Other Serious 70 Male 1/31/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Increased Other Serious 6/18/2010 39 Female 110 lb 2/15/2012 Physician Japan
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Life Threatening 12/28/2011 79 Male 117 lb 2/28/2012 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 2/19/2009 23 Female 3/5/2012 Physician Japan
Primary
Concomitant
Pericardial Effusion Other Serious 2/19/2009 23 Female 3/13/2012 Physician Japan
Primary
Concomitant
Delirium Hospitalization 5/12/2011 51 Male 117 lb 3/16/2012 Physician Korea, Republic Of
Primary
Concomitant
Asthenia Other Serious 5/12/2011 51 Male 117 lb 3/21/2012 Physician Korea, Republic Of
Primary
Concomitant
Renal Vasculitis 40 Male 3/22/2012 Other Health Professional India
Primary
Secondary
Hyperkalaemia Hospitalization 5/12/2011 51 Male 117 lb 4/4/2012 Physician Korea, Republic Of
Primary
Concomitant
Neutropenia Other Serious 5/12/2011 51 Male 117 lb 4/4/2012 Physician Korea, Republic Of
Primary
Concomitant
Lung Adenocarcinoma Other Serious 9/9/2010 Male 4/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphagia Hospitalization 5/19/2011 51 Male 4/10/2012 Korea, Republic Of
Primary
Concomitant
Hilar Lymphadenopathy Other Serious 5 Female 5/11/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Diarrhoea Other Serious 5/12/2011 51 Male 117 lb 5/22/2012 Physician Korea, Republic Of
Primary
Concomitant
C-reactive Protein Increased Hospitalization 4/11/2012 76 Female 135 lb 6/7/2012 Physician Japan
Primary
Concomitant
Pyrexia Life Threatening 12/28/2011 79 Male 117 lb 6/14/2012 Other Health Professional Japan
Primary
Concomitant
Condition Aggravated Hospitalization 3/1/2012 29 Female 115 lb 6/14/2012 Physician Japan
Primary
Secondary
Concomitant
Respiratory Disorder Death 10/18/2011 39 Male 6/15/2012 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 1/1/2012 68 Male 108 lb 6/18/2012 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Vascular Disorder Life Threatening 5/23/2011 57 Male 6/18/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Pressure Decreased Death 10/18/2011 39 Male 6/22/2012 Physician Japan
Primary
Concomitant
Bronchoalveolar Lavage Abnormal Hospitalization 3/1/2012 29 Female 115 lb 6/29/2012 Physician Japan
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Life Threatening 5/23/2011 57 Male 7/2/2012 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 69 Female 7/6/2012 Other Health Professional Spain
Primary
Concomitant
Interacting
Hypoxia Other Serious 5/28/2012 85 Female 101 lb 7/9/2012 Other Health Professional Japan
Primary
Concomitant
Hepatotoxicity Hospitalization 69 Female 7/9/2012 Other Health Professional Spain
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 4/9/2012 76 Female 135 lb 7/13/2012 Physician Japan
Primary
Concomitant
Neutrophil Count Decreased Hospitalization 3/8/2012 72 Male 159 lb 7/16/2012 Physician Japan
Primary
Concomitant
Tuberculosis Other Serious 1/1/2012 68 Male 108 lb 7/23/2012 Physician Japan
Primary
Secondary
Concomitant
Neutrophil Count Decreased Life Threatening 3/8/2012 72 Male 159 lb 7/24/2012 Physician Japan
Primary
Concomitant

Drug Data