Irinotecan combined with Oxaliplatin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Hospitalization 12/6/2005 61 Female 98 lb 3/13/2006 Other Health Professional United States
Primary
Secondary
Sepsis Hospitalization 12/6/2005 61 Female 98 lb 3/30/2006 Other Health Professional United States
Primary
Secondary
Sepsis Death 6/7/2005 55 Female 132 lb 5/1/2006 Physician Spain
Primary
Secondary
Concomitant
Sepsis Death 6/7/2005 Female 5/2/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 55 Female 132 lb 5/16/2006 Physician Spain
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/7/2005 Female 5/18/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Rash Other Serious 5/31/2006 50 Male 172 lb 5/31/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/29/2006 64 Male 190 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/30/2005 56 Female 163 lb 6/29/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Lymphangitis Other Serious 6/7/2006 35 Female 11/27/2006 Pharmacist Germany
Primary
Secondary
Concomitant
Pulmonary Fibrosis Disability 5/1/2006 74 161 lb 12/27/2006 Physician Germany
Primary
Secondary
Concomitant
Infusion Related Reaction Hospitalization 10/26/2006 64 Male 1/31/2007 Physician United States
Primary
Concomitant
Dehydration Hospitalization 2/4/2006 Male 2/16/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 1/2/2008 Other Health Professional Italy
Primary
Secondary
Ileus Hospitalization 10/24/2007 58 Male 1/22/2008 Consumer United States
Primary
Secondary
Hepatic Function Abnormal Hospitalization 11/5/2007 60 Male 1/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 12/8/2007 40 Female 1/23/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Myalgia Other Serious 9/1/2007 39 Female 133 lb 1/25/2008 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/1/2007 82 Female 2/1/2008 Physician Taiwan, Province Of China
Primary
Secondary
Sepsis Other Serious 2/11/2008 Canada
Primary
Secondary
Sepsis Other Serious 2/13/2008 Other Health Professional Canada
Primary
Secondary
Stomatitis Other Serious 12/1/2007 Male 2/14/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Death 12/29/2007 Male 2/14/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Swelling Face Life Threatening 1/7/2008 87 Male 163 lb 2/15/2008 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 1/5/2008 Male 2/21/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 8/14/2007 Male 2/22/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 12/1/2007 Male 2/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Ileus Life Threatening 9/18/2007 Female 160 lb 3/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 12/21/2007 40 Female 3/7/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Nephrotic Syndrome Other Serious 3/18/2006 Male 186 lb 3/11/2008 Other Health Professional Canada
Primary
Concomitant
Anaphylactic Shock Other Serious 5/15/2008 Female 7/3/2008 Consumer Japan
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/24/2008 Male 157 lb 7/3/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoaesthesia Disability 11/22/2007 Female 98 lb 7/22/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Death 68 Male 12/30/2008 Other Health Professional Spain
Primary
Concomitant
Haemolysis Life Threatening 12/1/2008 Female 1/16/2009 Physician United Kingdom
Primary
Concomitant
Septic Shock Hospitalization 8/12/2009 Male 298 lb 1/4/2010 Physician Germany
Primary
Concomitant
Thrombosis Other Serious 50 Male 3/18/2010 Physician Japan
Primary
Concomitant
Perineal Infection Death 9/24/2009 53 Male 163 lb 5/25/2010 Physician France
Primary
Secondary
Wound Dehiscence Other Serious 9/1/2007 46 Female 5/28/2010 Consumer United States
Primary
Secondary
Concomitant
Perineal Infection Death 9/24/2009 53 Male 6/1/2010 Physician France
Primary
Secondary
Perineal Infection Death 9/24/2009 53 Male 163 lb 6/4/2010 Physician France
Primary
Secondary
Death Death 5/1/2010 Female 6/11/2010 Physician Belgium
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 5/25/2010 57 Male 159 lb 6/24/2010 Physician Germany
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Hospitalization 5/25/2010 57 Male 159 lb 6/29/2010 Physician Germany
Primary
Secondary
Concomitant
Hypertension Other Serious 65 Female 1/19/2011 Physician Canada
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious Male 152 lb 2/14/2011 Physician Australia
Primary
Secondary
Concomitant
Leukocytosis Other Serious 47 Male 2/16/2011 Other Health Professional France
Primary
Concomitant
Diarrhoea Hospitalization 12/10/2010 Male 170 lb 2/16/2011 Physician United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 10/18/2007 38 Male 2/18/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Male 152 lb 2/21/2011 Physician Australia
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 3/11/2010 73 Female 115 lb 2/25/2011 Physician Italy
Primary
Secondary
Concomitant
Thrombosis Mesenteric Vessel Other Serious 47 Male 3/7/2011 Other Health Professional France
Primary
Concomitant
Disease Progression Death 4/16/2009 69 Male 3/8/2011 Consumer Japan
Primary
Secondary
Concomitant
Abnormal Behaviour Hospitalization 2/4/2011 66 Male 3/9/2011 Other Health Professional Italy
Primary
Concomitant
Cerebrovascular Accident Disability 8/29/2010 56 Female 108 lb 3/10/2011 Physician France
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 3/14/2011 Physician Austria
Primary
Secondary
Portal Vein Thrombosis Other Serious 3/29/2011 Physician United States
Primary
Secondary
Malaise Hospitalization 12/10/2010 Male 170 lb 4/4/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Other Serious 4/8/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Fall Hospitalization 3/12/2011 71 Male 159 lb 4/12/2011 Physician Canada
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious Female 4/13/2011 Physician United States
Primary
Secondary
Neutropenia Hospitalization 3/17/2011 71 Male 159 lb 4/14/2011 Physician Canada
Primary
Secondary
Concomitant
Acute Myocardial Infarction Other Serious 4/15/2011 Other Health Professional Italy
Primary
Secondary
Dyspnoea Death 3/10/2011 70 Male 134 lb 4/19/2011 Physician Italy
Primary
Concomitant
Constipation Death 12/9/2010 77 Female 126 lb 4/26/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Stomatitis Death 12/10/2010 78 Female 126 lb 12/18/2012 Physician Country Not Specified
Primary
Secondary
Concomitant
Multi-organ Failure Hospitalization 8/11/2011 68 Male 190 lb 10/16/2012 Consumer De
Primary
Secondary
Concomitant
Syncope Hospitalization 4/11/2012 52 Female 181 lb 9/14/2012 Consumer De
Primary
Secondary
Concomitant
Drug Effect Decreased Death Male 192 lb 12/3/2012 Physician Us
Primary
Secondary
Concomitant
Nausea Death 7/1/2012 63 Male 95 lb 12/19/2012 Physician Us
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 6/25/2012 51 Male 12/4/2012 Physician Ca
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 8/13/2012 9/4/2012 Physician At
Primary
Secondary
Skin Toxicity Other Serious 9/10/2012 Physician Us
Primary
Concomitant
Thrombocytopenia Other Serious 60 Male 8/22/2012 Us
Primary
Secondary
Concomitant
Skin Toxicity Hospitalization 72 Male 9/14/2012 Consumer De
Primary
Secondary
Skin Toxicity Other Serious 9/14/2012 Consumer Us
Primary
Secondary
Diarrhoea Other Serious 9/6/2012 Us
Primary
Secondary
Thrombocytopenia Required Intervention 35 Male 9/13/2012 Fr
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 9/6/2012 Us
Primary
Secondary
Fatigue Other Serious 9/6/2012 Us
Primary
Secondary
Neutropenia Other Serious 9/6/2012 Other Health Professional Us
Primary
Secondary
Diarrhoea Other Serious 9/6/2012 Other Health Professional Us
Primary
Secondary
Neutropenia Other Serious 9/7/2012 Other Health Professional Us
Primary
Secondary
Fatigue Other Serious 9/6/2012 Other Health Professional Us
Primary
Secondary
Febrile Neutropenia Hospitalization 9/6/2012 Other Health Professional Us
Primary
Secondary
Anaemia Other Serious 9/6/2012 Us
Primary
Secondary
Toxicity To Various Agents Other Serious 5/2/2011 64 Female 9/17/2012 Physician Us
Primary
Concomitant
Anaphylactic Reaction Other Serious 7/2/2012 57 Female 117 lb 9/13/2012 Pharmacist De
Primary
Secondary
Concomitant
Disease Progression Death Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Vision Blurred Death Male 9/24/2012 Physician Us
Primary
Secondary
Concomitant
Vomiting Other Serious Female 12/27/2012 Physician Us
Primary
Concomitant
Metastases To Lung Death 6/2005 Female 9/25/2012 Physician Us
Primary
Concomitant
Disease Progression Other Serious Female 12/4/2012 Physician Us
Primary
Secondary
Concomitant
Disease Progression Other Serious Male 9/26/2012 Physician Us
Primary
Secondary
Concomitant
Neutrophil Count Decreased Death Male 9/27/2012 Physician Us
Primary
Secondary
Pulmonary Mass Death 5/2004 Male 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization Female 9/27/2012 Physician Us
Primary
Secondary
Concomitant
Metastases To Liver Hospitalization 9/26/2012 63 Male 224 lb 9/28/2012 Us
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 8/22/2012 66 Female 141 lb 10/26/2012 Consumer Fi
Primary
Secondary
Concomitant
Tachycardia Hospitalization 6/14/2012 62 Female 10/3/2012 Other Health Professional Fr
Primary
Concomitant
Vein Pain Other Serious 2008 48 Male 159 lb 10/10/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Disease Progression Other Serious 6/4/2012 60 Female 183 lb 10/10/2012 Physician Ru
Primary
Secondary
Concomitant
Disease Progression Other Serious 9/13/2012 69 Male 154 lb 10/10/2012 Physician Ru
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/19/2012 63 Male 223 lb 10/4/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 1/2010 Female 148 lb 10/12/2012 Physician De
Primary
Secondary
Concomitant
Periodontitis Hospitalization 8/23/2012 65 Male 128 lb 10/16/2012 Physician De
Primary
Secondary
Concomitant
Disease Progression Other Serious 65 Female 176 lb 10/18/2012 Physician Br
Primary
Secondary
Concomitant
Neutropenia Hospitalization 9/24/2012 59 Male 11/19/2012 Physician De
Primary
Secondary
Disease Progression Other Serious 60 Female 108 lb 11/8/2012 Physician Br
Primary
Secondary
Concomitant
Disease Progression Other Serious 60 Female 154 lb 10/18/2012 Physician Br
Primary
Concomitant
Disease Progression Other Serious 66 Male 150 lb 10/19/2012 Physician Br
Primary
Secondary
Disease Progression Hospitalization 10/15/2012 53 Female 159 lb 10/19/2012 Physician Ru
Primary
Concomitant
Vomiting Hospitalization 9/21/2012 73 Male 181 lb 10/31/2012 Physician De
Primary
Secondary
Concomitant
Vein Pain Other Serious 2008 48 Male 159 lb 10/12/2012 Other Health Professional Us
Primary
Secondary
Disease Progression Other Serious 45 Female 123 lb 10/25/2012 Physician Br
Primary
Secondary
Concomitant
Tremor Hospitalization 10/12/2012 Male 173 lb 10/17/2012 Physician Us
Primary
Secondary
Neoplasm Malignant Other Serious 10/23/2012 Other Health Professional Us
Primary
Secondary
Disease Progression Other Serious 67 Male 179 lb 10/30/2012 Physician Br
Primary
Concomitant
Rash Pustular Hospitalization 8/18/2012 58 Male 11/23/2012 Consumer It
Primary
Secondary
Concomitant
Disease Progression Other Serious Male 157 lb 10/31/2012 Physician Br
Primary
Secondary
Vomiting Hospitalization 7/3/2012 74 Male 12/10/2012 Consumer De
Primary
Secondary
Vomiting Hospitalization 7/14/2012 74 Male 12/10/2012 Consumer De
Primary
Secondary
Disease Progression Other Serious 66 Female 115 lb 11/1/2012 Physician Br
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Other Serious 73 Male 157 lb 11/1/2012 Physician Br
Primary
Secondary
Tremor Hospitalization 10/12/2012 Male 173 lb 10/29/2012 Other Health Professional Us
Primary
Secondary
Vomiting Hospitalization 9/21/2012 72 Male 181 lb 11/8/2012 Physician De
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 9/29/2012 42 Female 11/9/2012 Physician Ca
Primary
Secondary
Concomitant
Vocal Cord Paralysis Other Serious 4/2010 34 Female 11/21/2012 Other Health Professional Tw
Primary
Secondary
Procedural Site Reaction Hospitalization 12/23/2010 58 Female 177 lb 11/6/2012 Other Health Professional De
Primary
Secondary
Concomitant
Vomiting Life Threatening 51 Female 11/15/2012 Physician Us
Primary
Secondary
Swollen Tongue Hospitalization 10/30/2012 66 Female 11/13/2012 Pharmacist Us
Primary
Secondary
Intestinal Obstruction Other Serious 47 Male 12/11/2012 Physician Country Not Specified
Primary
Concomitant
Liver Injury Other Serious 11/20/2012 Physician Country Not Specified
Primary
Secondary
Pulmonary Embolism Death 11/27/2012 Physician Pl
Primary
Secondary
Lower Respiratory Tract Infection Hospitalization 12/5/2011 73 Male 139 lb 11/27/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Nausea Hospitalization 11/19/2012 66 Female 153 lb 11/28/2012 Physician Us
Primary
Secondary
Disease Progression Death Female 8/25/2012 Physician Us
Primary
Concomitant
Hepatic Failure Life Threatening 9/5/2012 58 Female 185 lb 12/31/2012 Physician Ru
Primary
Secondary
Concomitant
Pulse Absent Death 11/18/2012 60 Male 260 lb 11/19/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 48 Female 12/3/2012 Physician Cz
Primary
Secondary
Concomitant
Vomiting Life Threatening 11/11/2012 62 Female 11/30/2012 Other Health Professional Cn
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 8/22/2012 66 Female 141 lb 12/7/2012 Physician Fi
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 64 Male 12/12/2012 Other Health Professional Tw
Primary
Concomitant
Nausea Hospitalization 12/5/2012 68 Male 138 lb 12/13/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Sinusitis Hospitalization 5/7/2010 66 Male 187 lb 12/24/2012 Physician Fi
Primary
Secondary
Sudden Death Death 11/25/2012 65 Male 251 lb 12/18/2012 Country Not Specified
Primary
Secondary
Vision Blurred Death Male 9/24/2012 Physician Us
Primary
Secondary
Concomitant
Disease Progression Other Serious 11/26/2012 60 Female 170 lb 12/24/2012 Physician Ru
Primary
Secondary
Concomitant
Proctitis Other Serious 12/26/2012 Physician Country Not Specified
Primary
Secondary
Disease Progression Other Serious 57 Male 9/11/2012 Physician Us
Primary
Secondary
Concomitant

Drug Data