Iressa combined with Radiotherapy

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pleural Effusion Other Serious 11/21/2005 75 Male 117 lb 1/2/2006 Physician Japan
Primary
Concomitant
Tachycardia Other Serious 12/25/2005 72 Male 159 lb 1/5/2006 Physician Finland
Primary
Secondary
Concomitant
Somnolence Hospitalization 9/8/2005 47 Male 128 lb 1/5/2006 Physician Japan
Primary
Concomitant
Chromaturia Hospitalization 8/13/2005 50 Female 117 lb 1/19/2006 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 10/15/2005 63 Male 1/23/2006 Physician Belgium
Primary
Secondary
Concomitant
Anaemia Hospitalization 8/25/2005 59 Male 115 lb 1/23/2006 Physician Italy
Primary
Secondary
Sepsis Other Serious 9/30/2004 Male 151 lb 1/24/2006 Physician Australia
Primary
Secondary
Concomitant
Malaise Hospitalization 11/16/2005 69 Female 1/26/2006 Physician Japan
Primary
Concomitant
Therapy Non-responder Other Serious 12/25/2005 72 Male 159 lb 1/27/2006 Physician Finland
Primary
Secondary
Concomitant
Sudden Death Death 11/3/2005 Male 1/31/2006 Physician Poland
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 12/23/2005 72 Male 159 lb 2/3/2006 Physician Finland
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/23/2006 71 Male 125 lb 2/6/2006 Physician Japan
Primary
Concomitant
Urinary Tract Disorder Hospitalization 3/11/2005 72 Male 166 lb 2/6/2006 Physician Finland
Primary
Secondary
Pleural Effusion Death 11/21/2005 75 Male 117 lb 2/7/2006 Physician Japan
Primary
Concomitant
Pneumonitis Other Serious 9/30/2004 70 Male 151 lb 2/13/2006 Physician Australia
Primary
Secondary
Concomitant
Urinary Tract Disorder Hospitalization 3/11/2005 72 Male 166 lb 2/13/2006 Physician Finland
Primary
Secondary
Pneumonitis Other Serious 9/30/2004 70 Male 151 lb 2/14/2006 Physician Australia
Primary
Secondary
Concomitant
Blood Creatinine Increased Other Serious 2/4/2006 63 Male 2/17/2006 Physician Germany
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 12/23/2005 72 Male 159 lb 2/20/2006 Physician Finland
Primary
Secondary
Concomitant
Vomiting Other Serious 2/4/2006 63 Male 2/22/2006 Physician Germany
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 10/7/2005 78 Female 115 lb 2/22/2006 Physician Japan
Primary
Concomitant
Insomnia Hospitalization 11/16/2005 69 Female 3/3/2006 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 1/29/2006 76 Male 150 lb 3/10/2006 Physician Japan
Primary
Concomitant
Stomatitis Necrotising Disability 12/7/2004 53 Male 110 lb 3/10/2006 Physician Spain
Primary
Secondary
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 3/16/2006 Physician Spain
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 3/17/2006 Physician Poland
Primary
Secondary
Concomitant
Shock Life Threatening 1/30/2006 48 Female 83 lb 3/17/2006 Physician Japan
Primary
Concomitant
Stupor Life Threatening 1/30/2006 48 Female 83 lb 3/21/2006 Physician Japan
Primary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 3/23/2006 Physician Poland
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 1/29/2006 76 Male 150 lb 3/27/2006 Physician Japan
Primary
Concomitant
Oesophagitis Hospitalization 11/5/2004 76 Female 3/27/2006 Physician Australia
Primary
Secondary
Concomitant
Gastric Ulcer Perforation Other Serious 11/5/2005 68 Male 4/4/2006 Physician Poland
Primary
Secondary
Concomitant
Fatigue Hospitalization 11/3/2005 Male 4/11/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Sudden Death Disability 11/3/2005 Male 4/14/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Impetigo Other Serious 3/20/2006 67 Female 4/17/2006 Physician Japan
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/21/2006 Physician Poland
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 4/28/2006 Physician Poland
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Hospitalization 7/14/2005 73 Male 5/3/2006 Physician Australia
Primary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 5/4/2006 Physician Poland
Primary
Secondary
Concomitant
Hypoxia Hospitalization 5/12/2004 76 Male 5/16/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 5/22/2006 Physician France
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 6/1/2006 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 6/9/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Other Serious 12/23/2005 72 Male 159 lb 6/9/2006 Physician Finland
Primary
Secondary
Concomitant
Pyrexia Life Threatening 5/10/2006 76 Male 126 lb 6/12/2006 Physician Japan
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 10/24/2005 54 Female 6/15/2006 Physician Japan
Primary
Concomitant
Renal Failure Hospitalization 3/28/2006 73 Male 159 lb 6/15/2006 Physician France
Primary
Secondary
Concomitant
Speech Disorder Life Threatening 5/10/2006 76 Male 126 lb 6/20/2006 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Recurrence Disability 11/5/2004 72 Male 6/21/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/11/2006 60 Female 6/23/2006 Physician United States
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/26/2006 Physician Australia
Primary
Secondary
Concomitant
Skin Reaction Other Serious 6/8/2006 65 Male 143 lb 6/26/2006 Physician France
Primary
Secondary
Concomitant
Pharyngeal Fistula Hospitalization 6/12/2006 48 Male 143 lb 6/30/2006 Physician Australia
Primary
Secondary
Concomitant
Protein Total Decreased Hospitalization 5/4/2006 64 Female 7/5/2006 Physician Belgium
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 4/11/2006 60 Female 7/7/2006 Physician United States
Primary
Secondary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 5/8/2006 69 Female 7/12/2006 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Life Threatening 6/26/2006 62 Female 7/13/2006 Physician Germany
Primary
Secondary
Concomitant
Skin Reaction Other Serious 6/8/2006 65 Male 143 lb 7/24/2006 Physician France
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 2/23/2006 71 Male 123 lb 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Venous Thrombosis Other Serious 10/7/2005 56 Female 187 lb 8/2/2006 Physician Italy
Primary
Secondary
Concomitant
Peritonitis Life Threatening 6/26/2006 62 Female 8/2/2006 Physician Germany
Primary
Secondary
Concomitant
Radiation Skin Injury Other Serious 6/8/2006 65 Male 143 lb 8/3/2006 Physician France
Primary
Secondary
Concomitant
Bronchopneumonia Death 2/23/2006 72 Male 123 lb 8/3/2006 Physician Japan
Primary
Secondary
Concomitant
Tachycardia Other Serious 12/23/2005 72 Male 159 lb 8/3/2006 Physician Finland
Primary
Secondary
Concomitant
Helicobacter Pylori Identification Test Positive Hospitalization 7/17/2006 47 Male 8/4/2006 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/3/2005 49 Male 8/21/2006 Physician India
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/1/2006 Physician Japan
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/5/2006 Physician Japan
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Death 5/9/2006 47 Male 172 lb 9/15/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/4/2006 63 Male 9/18/2006 Physician Australia
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 9/4/2006 63 Male 9/21/2006 Physician Australia
Primary
Secondary
Concomitant
Hepatic Function Abnormal Life Threatening 3/22/2006 66 Female 9/29/2006 Physician Poland
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 11/8/2004 51 Male 142 lb 10/24/2006 Physician Spain
Primary
Secondary
Concomitant
Disseminated Intravascular Coagulation Disability 10/12/2006 75 Male 10/24/2006 Physician Japan
Primary
Concomitant
Pyrexia Death 9/1/2006 76 Male 141 lb 10/31/2006 Physician Japan
Primary
Concomitant
Skin Erosion Other Serious 9/1/2006 70 Female 11/3/2006 Physician Japan
Primary
Concomitant
Drug Ineffective Death 9/1/2006 76 Male 141 lb 11/3/2006 Physician Japan
Primary
Concomitant
Respiratory Arrest Death 3/4/2006 Female 11/14/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/4/2006 63 Female 11/22/2006 Physician Taiwan, Province Of China
Primary
Concomitant
Respiratory Arrest Death 3/4/2006 Female 11/29/2006 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 11/4/2006 63 Female 11/30/2006 Physician Taiwan, Province Of China
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/1/2006 61 Female 121 lb 12/14/2006 Physician Japan
Primary
Concomitant
Acute Promyelocytic Leukaemia Life Threatening 3/1/2004 51 Female 12/14/2006 Other Health Professional Japan
Primary
Concomitant
Pneumonia Hospitalization 11/19/2006 55 Male 12/21/2006 Pharmacist Japan
Primary
Concomitant
Spinal Disorder Other Serious 9/18/2006 51 Male 150 lb 12/21/2006 Physician Japan
Primary
Concomitant
Skin Ulcer Other Serious 8/1/2006 52 Male 12/21/2006 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/19/2006 55 Male 12/26/2006 Pharmacist Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/20/2006 61 Female 121 lb 1/2/2007 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 11/19/2006 55 Male 1/22/2007 Pharmacist Japan
Primary
Concomitant
Acute Myocardial Infarction Death 1/17/2007 68 Male 89 lb 1/22/2007 Physician Singapore
Primary
Secondary
Concomitant
Rash Death 9/1/2005 77 Female 110 lb 1/26/2007 Physician Japan
Primary
Concomitant
Rash Death 9/1/2005 77 Female 110 lb 2/2/2007 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Hospitalization 11/16/2006 58 Male 123 lb 2/6/2007 Physician France
Primary
Secondary
Hyperthermia Hospitalization 10/3/2006 58 Male 123 lb 2/6/2007 Physician France
Primary
Secondary
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/14/2007 Physician Singapore
Primary
Secondary
Concomitant
Pneumonia Death 1/22/2007 77 Male 99 lb 2/15/2007 Physician Japan
Primary
Concomitant
Intestinal Ischaemia Life Threatening 6/26/2006 62 Female 2/19/2007 Physician Germany
Primary
Secondary
Concomitant
Nasal Congestion Hospitalization 11/14/2006 37 Female 106 lb 2/20/2007 Physician Japan
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/21/2007 Physician Singapore
Primary
Secondary
Concomitant
Myocardial Ischaemia Death 1/17/2007 68 Male 89 lb 2/21/2007 Physician Singapore
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 11/14/2006 37 Female 106 lb 3/13/2007 Physician Japan
Primary
Secondary
Concomitant
Lung Disorder Death 1/19/2007 72 Female 90 lb 3/14/2007 Physician Japan
Primary
Concomitant
Hyperthermia Hospitalization 10/3/2006 58 Male 123 lb 3/22/2007 Physician France
Primary
Secondary
General Physical Health Deterioration Hospitalization 11/16/2006 58 Male 123 lb 3/26/2007 Physician France
Primary
Secondary
Concomitant
Nausea Life Threatening 8/19/2006 64 Female 131 lb 3/27/2007 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2007 77 Female 93 lb 4/18/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 11/25/2006 55 Male 101 lb 4/25/2007 Pharmacist Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 3/29/2007 67 Male 110 lb 4/25/2007 Physician Japan
Primary
Concomitant
Lung Disorder Death 1/19/2007 72 Female 90 lb 4/25/2007 Physician Japan
Primary
Concomitant
Eosinophilic Pneumonia Other Serious 6/28/2006 52 Female 104 lb 4/23/2007 Physician Japan
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 4/27/2007 Physician Poland
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 3/26/2007 77 Female 93 lb 5/1/2007 Physician Japan
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/5/2007 67 Female 117 lb 5/4/2007 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/6/2007 71 Female 5/11/2007 Physician Japan
Primary
Concomitant
Acute Myeloid Leukaemia Death 2/6/2007 71 Female 84 lb 5/14/2007 Physician Japan
Primary
Concomitant
Thrombocytopenia Life Threatening 3/29/2007 67 Male 110 lb 5/16/2007 Physician Japan
Primary
Concomitant
Pseudomembranous Colitis Hospitalization 4/8/2007 67 Female 117 lb 5/17/2007 Physician Japan
Primary
Concomitant
Gastritis Other Serious 6/28/2006 52 Female 104 lb 5/17/2007 Physician Japan
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 5/25/2007 Physician Poland
Primary
Secondary
Concomitant
Gastric Ulcer Hospitalization 7/17/2006 47 Male 6/4/2007 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Haematemesis Other Serious 12/3/2005 49 Male 6/5/2007 Physician India
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 3/22/2006 66 Female 7/3/2007 Physician Poland
Primary
Secondary
Concomitant
Stomatitis Death 1/15/2007 71 Male 7/9/2007 Physician Poland
Primary
Secondary
Concomitant
Sepsis Hospitalization 5/28/2007 69 Male 97 lb 7/9/2007 Physician Singapore
Primary
Secondary
Concomitant
Shock Death 4/18/2007 71 Female 102 lb 7/9/2007 Physician Japan
Primary
Concomitant
Sudden Death Disability 11/3/2005 73 Male 7/11/2007 Physician Poland
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/8/2007 80 Female 7/17/2007 Physician Japan
Primary
Secondary
Concomitant
Acute Prerenal Failure Other Serious 11/21/2005 56 Male 7/24/2007 Physician Poland
Primary
Secondary
Concomitant
Hypokalaemia Other Serious 11/24/2005 51 Female 7/25/2007 Physician India
Primary
Secondary
Respiratory Failure Other Serious 1/28/2003 66 Male 8/3/2007 Consumer Australia
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/8/2007 80 Female 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/22/2007 61 Female 130 lb 9/4/2007 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 3/26/2007 77 Female 93 lb 9/5/2007 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 1/15/2007 71 Male 10/22/2007 Physician Poland
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 12/17/2006 54 Male 108 lb 11/16/2007 Physician Singapore
Primary
Secondary
Concomitant
Intestinal Ischaemia Life Threatening 6/26/2006 62 Female 12/4/2007 Physician Germany
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/22/2007 61 Female 130 lb 12/5/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Life Threatening 9/25/2007 79 Male 88 lb 1/2/2008 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 1/15/2007 71 Male 2/18/2008 Physician Poland
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/15/2007 71 Male 2/26/2008 Physician Poland
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 1/10/2008 73 Female 93 lb 2/27/2008 Physician Japan
Primary
Secondary
Concomitant
Nausea Death 1/5/2008 76 Male 104 lb 4/14/2008 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 4/27/2008 70 Male 5/8/2008 Physician China
Primary
Concomitant
Pneumonia Hospitalization 3/17/2008 79 Female 112 lb 6/10/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/27/2008 70 Male 7/15/2008 Physician China
Primary
Concomitant
Fatigue Death 11/3/2005 73 Male 10/13/2008 Physician Poland
Primary
Secondary
Concomitant
Peritonitis Life Threatening 6/26/2006 62 Female 11/3/2008 Physician Germany
Primary
Secondary
Concomitant
Leukoencephalopathy Hospitalization 11/19/2008 81 Female 12/2/2008 Physician Japan
Primary
Secondary
Concomitant
Leukoencephalopathy Other Serious 1/10/2008 73 Female 93 lb 2/11/2009 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Disability 1/9/2008 75 Female 93 lb 3/2/2009 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data