Thrombotic Stroke |
Death |
10/27/2005 |
45 |
Female |
|
1/25/2006 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Urine Output Decreased |
Hospitalization |
11/19/2005 |
|
Male |
208 lb |
1/3/2006 |
Pharmacist |
United States |
|
Renal Tubular Necrosis |
Hospitalization |
1/24/2006 |
66 |
Male |
317 lb |
2/9/2006 |
Pharmacist |
United States |
|
Thrombocytopenia |
Death |
3/26/2006 |
73 |
Male |
|
4/24/2006 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Renal Failure Acute |
Hospitalization |
5/16/2006 |
63 |
Male |
164 lb |
5/25/2006 |
Pharmacist |
United States |
|
Myoclonus |
Hospitalization |
4/23/2006 |
|
Male |
|
7/18/2006 |
Pharmacist |
United States |
|
Febrile Neutropenia |
Other Serious |
7/11/2006 |
71 |
Male |
|
8/22/2006 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Torsade De Pointes |
Life Threatening |
|
33 |
Female |
99 lb |
9/5/2006 |
Physician |
Netherlands |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vascular Calcification |
Life Threatening |
10/15/2005 |
67 |
Male |
183 lb |
9/8/2006 |
|
United States |
|
Vascular Calcification |
Life Threatening |
10/15/2005 |
67 |
Male |
183 lb |
9/28/2006 |
|
United States |
|
Linear Iga Disease |
Death |
9/1/2005 |
83 |
Male |
187 lb |
9/21/2006 |
Pharmacist |
United States |
|
Sepsis |
Life Threatening |
2/26/2007 |
89 |
Male |
187 lb |
3/2/2007 |
Other Health Professional |
United States |
|
Ventricular Fibrillation |
Life Threatening |
12/30/2006 |
81 |
Male |
|
4/25/2007 |
Pharmacist |
United States |
|
Small Intestinal Haemorrhage |
Life Threatening |
4/24/2005 |
44 |
Female |
|
5/9/2007 |
Physician |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pancytopenia |
Hospitalization |
2/17/2006 |
81 |
Female |
|
7/23/2007 |
Pharmacist |
United States |
|
Respiratory Failure |
Hospitalization |
6/5/2007 |
58 |
Male |
145 lb |
8/22/2007 |
Pharmacist |
United States |
|
Upper Gastrointestinal Haemorrhage |
Hospitalization |
6/21/2007 |
|
Male |
142 lb |
9/21/2007 |
Other Health Professional |
United States |
|
Sepsis |
Life Threatening |
12/24/2006 |
|
Male |
174 lb |
10/17/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Life Threatening |
12/24/2006 |
|
Male |
174 lb |
10/25/2007 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Hospitalization |
11/25/2007 |
70 |
Male |
|
2/18/2008 |
Physician |
United States |
|
Tinnitus |
Hospitalization |
|
47 |
Female |
|
3/7/2008 |
Pharmacist |
United States |
|
Sepsis |
Hospitalization |
11/25/2007 |
70 |
Male |
|
3/31/2008 |
Physician |
United States |
|
Stenotrophomonas Infection |
Other Serious |
12/14/2006 |
79 |
Female |
|
4/28/2008 |
|
Taiwan, Province Of China |
|
White Blood Cell Count Decreased |
Hospitalization |
6/21/2007 |
81 |
Male |
142 lb |
5/2/2008 |
Other Health Professional |
United States |
|
Pyogenic Granuloma |
Other Serious |
|
|
|
|
5/28/2008 |
Other Health Professional |
Spain |
|
Urinary Tract Infection Staphylococcal |
Hospitalization |
6/21/2007 |
81 |
Male |
142 lb |
5/21/2008 |
Other Health Professional |
United States |
|
Tachycardia |
Hospitalization |
3/5/2008 |
81 |
Female |
|
5/23/2008 |
Pharmacist |
United States |
|
Urinary Tract Infection Bacterial |
Hospitalization |
6/21/2007 |
81 |
Male |
142 lb |
6/26/2008 |
Other Health Professional |
United States |
|
Sepsis |
Other Serious |
|
0 |
Male |
|
7/10/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pyrexia |
Hospitalization |
8/28/2008 |
|
|
|
9/16/2008 |
Pharmacist |
United States |
|
Scrotal Gangrene |
Hospitalization |
10/10/2008 |
|
Male |
166 lb |
10/24/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Tremor |
Other Serious |
8/13/2008 |
52 |
Male |
243 lb |
10/24/2008 |
Other Health Professional |
United States |
|
Neuralgic Amyotrophy |
Disability |
|
22 |
Male |
|
11/13/2008 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Tremor |
Other Serious |
8/13/2008 |
52 |
Male |
243 lb |
11/14/2008 |
Other Health Professional |
United States |
|
Proctalgia |
Hospitalization |
10/10/2008 |
|
Male |
166 lb |
11/17/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Proctalgia |
Hospitalization |
10/10/2008 |
|
Male |
166 lb |
12/3/2008 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Respiratory Failure |
Other Serious |
11/23/2008 |
|
|
|
1/5/2009 |
Physician |
Chile |
Primary |
|
Secondary |
|
Concomitant |
|
|
Shock |
Other Serious |
11/23/2008 |
76 |
Male |
185 lb |
1/9/2009 |
Other Health Professional |
Canada |
|
Sepsis |
Death |
10/12/2008 |
63 |
Female |
257 lb |
1/21/2009 |
Pharmacist |
United States |
|
Vomiting |
Life Threatening |
1/18/2009 |
80 |
Male |
132 lb |
1/27/2009 |
|
United States |
|
Vomiting |
Life Threatening |
1/18/2009 |
80 |
Male |
132 lb |
1/27/2009 |
|
United States |
|
Pneumonia Cryptococcal |
Hospitalization |
11/22/2008 |
|
Male |
220 lb |
2/9/2009 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Urinary Incontinence |
Other Serious |
12/15/2008 |
|
Female |
|
3/6/2009 |
|
Canada |
|
Ventricular Tachycardia |
Other Serious |
7/1/2008 |
|
Male |
207 lb |
3/9/2009 |
Pharmacist |
|
|
Respiratory Failure |
Other Serious |
11/23/2008 |
|
|
|
3/24/2009 |
Physician |
Chile |
Primary |
|
Secondary |
|
Concomitant |
|
|
Respiratory Depression |
Other Serious |
|
81 |
Male |
|
6/26/2009 |
|
Canada |
Primary |
|
Concomitant |
|
Interacting |
|
|
Upper Gastrointestinal Haemorrhage |
Other Serious |
|
81 |
Male |
|
6/29/2009 |
Physician |
Canada |
Primary |
|
Secondary |
|
Concomitant |
|
|
Unresponsive To Stimuli |
Hospitalization |
|
81 |
Male |
|
7/2/2009 |
Physician |
Canada |
Primary |
|
Secondary |
|
Concomitant |
|
|
Respiratory Failure |
Hospitalization |
|
81 |
Male |
|
7/9/2009 |
Other Health Professional |
Canada |
Primary |
|
Secondary |
|
Concomitant |
|
|
Tachycardia |
Hospitalization |
|
81 |
Male |
|
7/9/2009 |
|
|
Primary |
|
Secondary |
|
Concomitant |
|
|
Respiratory Depression |
Other Serious |
|
81 |
Male |
|
7/13/2009 |
Physician |
Canada |
Primary |
|
Concomitant |
|
Interacting |
|
|
Ureteric Cancer |
Death |
|
71 |
Male |
|
7/22/2009 |
|
United States |
|
Troponin Increased |
Hospitalization |
|
|
Female |
|
8/6/2009 |
|
United States |
|
Neoplasm Progression |
Life Threatening |
1/18/2009 |
|
Male |
132 lb |
8/10/2009 |
|
United States |
|
Ureteric Cancer |
Death |
|
71 |
Male |
|
8/4/2009 |
|
United States |
|
Wheezing |
Other Serious |
3/6/2009 |
|
Male |
144 lb |
8/18/2009 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Ureteric Cancer |
Hospitalization |
|
66 |
Male |
|
9/8/2009 |
|
United States |
|
Wheezing |
Hospitalization |
|
66 |
Male |
|
10/17/2009 |
|
United States |
|
Multi-organ Failure |
Other Serious |
|
67 |
|
|
10/26/2009 |
Physician |
Japan |
|
Pancreatic Necrosis |
Hospitalization |
12/1/2008 |
63 |
Female |
|
11/18/2009 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Septic Shock |
Other Serious |
11/23/2008 |
68 |
Female |
165 lb |
11/26/2009 |
Physician |
Chile |
Primary |
|
Secondary |
|
Concomitant |
|
|
Multi-organ Failure |
Other Serious |
12/10/2006 |
67 |
Male |
155 lb |
12/7/2009 |
Physician |
Japan |
|
Multi-organ Failure |
Other Serious |
12/10/2006 |
67 |
Male |
155 lb |
12/7/2009 |
Physician |
Japan |
|
Multi-organ Failure |
Other Serious |
12/10/2006 |
66 |
Male |
155 lb |
2/1/2010 |
Physician |
Japan |
|
Vascular Insufficiency |
Other Serious |
10/1/2007 |
77 |
Female |
|
3/4/2010 |
Lawyer |
United States |
|
Lung Neoplasm Malignant |
Other Serious |
1/1/2008 |
73 |
Male |
|
6/10/2010 |
Lawyer |
United States |
|
Prothrombin Time Prolonged |
|
1/26/2007 |
76 |
Female |
204 lb |
6/24/2010 |
Other Health Professional |
United States |
|
Vasoconstriction |
Required Intervention |
1/21/2008 |
77 |
Female |
|
6/30/2010 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Unresponsive To Stimuli |
Other Serious |
12/1/2007 |
50 |
Male |
309 lb |
7/19/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Haemorrhage |
Hospitalization |
|
82 |
Male |
175 lb |
7/22/2010 |
Pharmacist |
United States |
|
Sinus Tachycardia |
Other Serious |
10/1/2007 |
71 |
Male |
165 lb |
8/5/2010 |
Other Health Professional |
United States |
|
Lung Neoplasm Malignant |
Other Serious |
1/1/2008 |
72 |
Male |
|
8/5/2010 |
Other Health Professional |
United States |
|
Ventricular Fibrillation |
Other Serious |
5/17/2010 |
55 |
Male |
147 lb |
9/2/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
Other Serious |
2/6/2008 |
51 |
Male |
163 lb |
9/21/2010 |
Other Health Professional |
United States |
|
Vomiting |
Other Serious |
10/2/2007 |
78 |
Male |
|
9/27/2010 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Other Serious |
4/17/2008 |
71 |
Male |
|
9/30/2010 |
Lawyer |
United States |
|
Vomiting |
Other Serious |
1/1/2008 |
32 |
Male |
295 lb |
10/6/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Toxic Skin Eruption |
Hospitalization |
8/26/2010 |
97 |
Female |
121 lb |
10/8/2010 |
Physician |
Portugal |
|
Vomiting |
Other Serious |
12/14/2007 |
69 |
Male |
187 lb |
10/11/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Unresponsive To Stimuli |
Other Serious |
12/1/2007 |
50 |
Male |
309 lb |
10/14/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
Other Serious |
10/2/2007 |
78 |
Male |
|
11/18/2010 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Unresponsive To Stimuli |
Other Serious |
12/1/2007 |
50 |
Male |
309 lb |
12/1/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
Other Serious |
1/1/2008 |
32 |
Male |
295 lb |
12/2/2010 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Other Serious |
4/17/2008 |
71 |
Male |
|
12/6/2010 |
Physician |
United States |
|
Urinary Tract Infection |
Other Serious |
1/15/2008 |
60 |
Male |
|
12/15/2010 |
Other Health Professional |
United States |
|
Hyperkalaemia |
Other Serious |
2/9/2010 |
66 |
Male |
|
12/22/2010 |
|
Belgium |
Primary |
|
Secondary |
|
Concomitant |
|
|
Cardiac Disorder |
Other Serious |
4/17/2008 |
71 |
Male |
139 lb |
1/20/2011 |
Other Health Professional |
United States |
|
Urinary Retention |
Other Serious |
1/1/2008 |
32 |
Male |
295 lb |
1/27/2011 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Vomiting |
Hospitalization |
12/14/2007 |
69 |
Male |
187 lb |
1/31/2011 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Aspiration |
Other Serious |
1/1/2006 |
49 |
Female |
128 lb |
2/7/2011 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pneumatosis Intestinalis |
Other Serious |
10/25/2010 |
72 |
Male |
159 lb |
2/22/2011 |
Other Health Professional |
France |
|
Pneumatosis Intestinalis |
Other Serious |
10/25/2010 |
72 |
Male |
159 lb |
3/2/2011 |
Other Health Professional |
France |
|
Respiratory Failure |
Death |
12/1/2007 |
50 |
Male |
309 lb |
3/4/2011 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Life Threatening |
10/22/2010 |
72 |
Male |
159 lb |
3/11/2011 |
Other Health Professional |
France |
|
Urinary Retention |
Other Serious |
6/1/2006 |
78 |
Male |
200 lb |
3/16/2011 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Coronary Artery Stenosis |
Hospitalization |
|
74 |
Female |
|
3/3/2011 |
Lawyer |
United States |
|
Unevaluable Event |
Other Serious |
2/14/2007 |
59 |
Male |
180 lb |
3/24/2011 |
Lawyer |
United States |
|
Renal Failure |
Other Serious |
2/14/2007 |
59 |
Male |
180 lb |
3/24/2011 |
Lawyer |
United States |
|
Abdominal Pain Upper |
Death |
6/1/2006 |
78 |
Male |
200 lb |
3/28/2011 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Peritonitis |
Hospitalization |
10/22/2010 |
72 |
Male |
154 lb |
3/30/2011 |
Other Health Professional |
France |
|
Paraesthesia |
Death |
6/1/2006 |
78 |
Male |
200 lb |
4/1/2011 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Medication Error |
Other Serious |
10/22/2010 |
72 |
Male |
154 lb |
4/4/2011 |
Other Health Professional |
France |
|
Multi-organ Failure |
Other Serious |
|
32 |
Male |
297 lb |
3/23/2011 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Urinary Retention |
Other Serious |
6/1/2006 |
78 |
Male |
200 lb |
4/8/2011 |
Lawyer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Condition Aggravated |
Hospitalization |
12/1/2010 |
33 |
Male |
|
4/22/2011 |
Other Health Professional |
France |
Primary |
|
Secondary |
|
Concomitant |
|
|
Neoplasm Malignant |
Other Serious |
6/1/2006 |
78 |
Male |
200 lb |
5/13/2011 |
Physician |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Death |
Death |
|
|
Male |
|
5/13/2011 |
Physician |
United States |
|
Dystonia |
Other Serious |
7/1/2009 |
58 |
Female |
175 lb |
5/23/2011 |
Lawyer |
United States |
|
Drug Administration Error |
Life Threatening |
6/1/2011 |
83 |
Female |
198 lb |
6/14/2011 |
Pharmacist |
Portugal |
|
Heparin-induced Thrombocytopenia |
Other Serious |
1/1/1996 |
53 |
Female |
212 lb |
6/15/2011 |
Consumer |
United States |
|
Thrombocytopenia |
Other Serious |
12/25/2009 |
63 |
Female |
|
6/22/2011 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Drug Dose Omission |
Hospitalization |
4/5/2010 |
24 |
Female |
|
7/18/2011 |
Consumer |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Gastrooesophageal Reflux Disease |
Hospitalization |
4/5/2010 |
24 |
Female |
|
7/19/2011 |
|
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Traumatic Haemorrhage |
Death |
5/2/2011 |
68 |
Male |
170 lb |
8/5/2011 |
Pharmacist |
United States |
|
Lobar Pneumonia |
Disability |
11/8/2009 |
72 |
Male |
124 lb |
9/12/2011 |
Physician |
United States |
|
Anaemia |
Life Threatening |
|
69 |
Male |
187 lb |
10/31/2011 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pneumonia Primary Atypical |
Hospitalization |
9/26/2011 |
67 |
Female |
104 lb |
11/14/2011 |
Other Health Professional |
United States |
|
Pneumonia |
Other Serious |
9/2/2011 |
74 |
Male |
177 lb |
11/15/2011 |
Physician |
United States |
|
Acute Respiratory Distress Syndrome |
Death |
9/26/2011 |
67 |
Female |
104 lb |
11/22/2011 |
Consumer |
United States |
|
Chronic Obstructive Pulmonary Disease |
Disability |
11/8/2009 |
72 |
Male |
124 lb |
12/1/2011 |
Physician |
United States |
|
Multi-organ Failure |
Hospitalization |
9/26/2011 |
67 |
Female |
104 lb |
12/9/2011 |
Other Health Professional |
United States |
|
Cardiac Failure |
Death |
11/26/2011 |
86 |
Male |
|
12/13/2011 |
Other Health Professional |
United States |
|
Heparin-induced Thrombocytopenia |
Hospitalization |
1/16/2012 |
66 |
Male |
141 lb |
1/20/2012 |
Pharmacist |
United States |
|
Mental Status Changes |
Death |
9/2/2011 |
74 |
Male |
177 lb |
3/2/2012 |
Physician |
United States |
|
Dyspnoea |
Hospitalization |
|
|
Female |
|
3/11/2012 |
Physician |
United States |
|
Haemoptysis |
Death |
|
|
Female |
205 lb |
3/23/2012 |
Lawyer |
United States |
|
Hypotension |
Hospitalization |
2/4/2012 |
88 |
Female |
189 lb |
2/9/2012 |
Pharmacist |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Diverticulum |
Death |
|
66 |
Male |
185 lb |
4/6/2012 |
Lawyer |
United States |
|
Urinary Tract Infection |
Disability |
|
69 |
Female |
165 lb |
4/24/2012 |
Consumer |
United States |
|
Toxic Skin Eruption |
Hospitalization |
4/1/2012 |
39 |
Male |
|
4/24/2012 |
Physician |
France |
|
Vulvovaginal Candidiasis |
Other Serious |
2/6/2006 |
57 |
Female |
233 lb |
4/27/2012 |
Consumer |
United States |
|
Acute Respiratory Distress Syndrome |
Death |
9/26/2011 |
67 |
Female |
104 lb |
5/24/2012 |
Other Health Professional |
United States |
|
Cerebellar Syndrome |
Other Serious |
1/1/2008 |
54 |
Male |
125 lb |
6/19/2012 |
Lawyer |
United States |
|
Renal Failure Acute |
Death |
2/8/2012 |
70 |
Male |
160 lb |
6/29/2012 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Endotracheal Intubation |
Hospitalization |
6/25/2012 |
60 |
Male |
|
7/2/2012 |
Other Health Professional |
United States |
|
Liver Injury |
Hospitalization |
4/1/2012 |
64 |
Female |
|
7/3/2012 |
Physician |
France |
Primary |
|
Secondary |
|
Concomitant |
|
|
Renal Failure Acute |
Other Serious |
12/14/2010 |
89 |
Male |
|
7/10/2012 |
Other Health Professional |
India |
|
Diverticulitis |
Hospitalization |
12/14/2010 |
89 |
Male |
|
7/12/2012 |
Consumer |
India |
|
Pyrexia |
Hospitalization |
4/1/2012 |
64 |
Female |
|
7/12/2012 |
Physician |
France |
Primary |
|
Secondary |
|
Concomitant |
|
|
Anaemia |
Hospitalization |
12/14/2010 |
89 |
Male |
|
7/27/2012 |
Consumer |
India |
|
Intentional Drug Misuse |
Hospitalization |
4/5/2010 |
24 |
Female |
|
7/30/2012 |
Other Health Professional |
United States |
Primary |
|
Secondary |
|
Concomitant |
|
|
Hyperkalaemia |
Other Serious |
2/9/2010 |
|
|
|
7/31/2012 |
Consumer |
Netherlands |
Primary |
|
Secondary |
|
Concomitant |
|
|
Sepsis |
Hospitalization |
4/1/2012 |
64 |
Male |
|
8/16/2012 |
Physician |
United States |
|
Acute Myeloid Leukaemia |
Death |
2/8/2012 |
70 |
Male |
160 lb |
8/17/2012 |
Other Health Professional |
United Kingdom |
Primary |
|
Secondary |
|
Concomitant |
|
|
Pneumonitis |
Hospitalization |
9/26/2011 |
67 |
Female |
104 lb |
11/16/2012 |
Consumer |
Us |
|
Renal Failure |
Other Serious |
4/2/2011 |
|
|
|
10/9/2012 |
Physician |
De |
|
Sepsis |
Hospitalization |
12/17/2012 |
66 |
Male |
185 lb |
12/28/2012 |
Physician |
Us |
|
Rhabdomyolysis |
|
11/25/2012 |
36 |
Female |
200 lb |
1/10/2013 |
Physician |
Us |
|
Hyperpyrexia |
Life Threatening |
11/25/2012 |
36 |
Female |
200 lb |
2/4/2013 |
Physician |
Us |
|
Hyperpyrexia |
|
11/25/2012 |
36 |
Female |
200 lb |
2/5/2013 |
Physician |
Us |
|