Interferon Alfa combined with Sunitinib Malate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Decreased Other Serious 11/14/2008 1/8/2009 Physician Japan
Primary
Concomitant
Diabetic Neuropathy Hospitalization 2/4/2008 1/19/2009 Physician Russian Federation
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/14/2008 2/18/2009 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 5/2/2009 62 6/10/2009 Physician Japan
Primary
Concomitant
Cholecystitis Acute Hospitalization 4/30/2009 62 7/6/2009 Physician Japan
Primary
Concomitant
Hypothyroidism Other Serious 6/6/2009 69 Male 141 lb 8/4/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 9/1/2009 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/14/2008 67 9/18/2009 Physician Japan
Primary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 11/23/2009 Physician Japan
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 7/7/2009 78 Male 104 lb 1/20/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/2/2009 52 Male 179 lb 4/29/2010 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 5/24/2010 56 Male 7/21/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 8/13/2010 Physician Japan
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death Male 8/18/2010 Consumer Netherlands
Primary
Secondary
White Blood Cell Count Increased Other Serious 5/24/2010 56 Male 8/24/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2010 64 Male 90 lb 9/3/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/16/2010 74 Male 159 lb 9/23/2010 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 7/8/2010 65 Male 146 lb 9/29/2010 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2010 64 Male 90 lb 10/1/2010 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 6/23/2010 65 Male 146 lb 10/7/2010 Physician Japan
Primary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 10/11/2010 Physician Japan
Primary
Concomitant
Pleurodesis Other Serious Male 10/14/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/16/2010 74 Male 159 lb 10/15/2010 Physician Japan
Primary
Concomitant
Osteomyelitis Other Serious 6/2/2010 45 Male 10/20/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 8/21/2010 78 Male 10/26/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/8/2010 Other Health Professional Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/10/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/21/2010 64 Male 90 lb 11/11/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/5/2010 63 Female 11/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Male 11/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Disorder Hospitalization 6/29/2010 68 Female 115 lb 11/19/2010 Physician Japan
Primary
Concomitant
Pneumonia Other Serious 9/1/2010 78 Female 11/24/2010 Physician Japan
Primary
Concomitant
Pleurodesis Other Serious 6/30/2010 58 Male 172 lb 11/25/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 5/26/2010 62 Male 11/30/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 7/30/2010 54 Male 11/30/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 11/1/2010 70 Male 11/30/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 6/28/2010 59 Male 11/30/2010 Physician Japan
Primary
Concomitant
Blood Amylase Increased Other Serious Male 170 lb 11/30/2010 Other Health Professional Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Hospitalization 11/18/2010 59 Male 132 lb 12/2/2010 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 8/21/2010 78 Male 12/8/2010 Physician Japan
Primary
Concomitant
Renal Impairment Other Serious 7/30/2010 54 Male 12/14/2010 Physician Japan
Primary
Concomitant
Malaise Other Serious 7/17/2010 67 Male 12/14/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 9/16/2010 75 Male 119 lb 12/16/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 8/9/2010 63 Female 12/16/2010 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 12/20/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 10/5/2010 64 Male 119 lb 12/20/2010 Physician Japan
Primary
Concomitant
Malaise Life Threatening 10/14/2010 59 Male 132 lb 12/20/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 7/17/2010 67 Male 12/21/2010 Physician Japan
Primary
Concomitant
Pleural Effusion Other Serious 6/30/2010 58 Male 172 lb 12/22/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/16/2010 74 Male 159 lb 12/23/2010 Physician Japan
Primary
Concomitant
Cerebral Haemorrhage Life Threatening 10/16/2010 67 Male 141 lb 12/23/2010 Physician Japan
Primary
Concomitant
Small Intestinal Haemorrhage Hospitalization 11/21/2010 54 Male 163 lb 12/28/2010 Physician Japan
Primary
Concomitant
Stomatitis Life Threatening 6/23/2010 65 Male 146 lb 12/28/2010 Physician Japan
Primary
Concomitant
Platelet Count Increased Other Serious 7/5/2010 63 Female 126 lb 12/29/2010 Physician Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/16/2010 74 Male 159 lb 12/29/2010 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/21/2010 78 Male 1/7/2011 Physician Japan
Primary
Concomitant
Malaise Hospitalization 10/14/2010 59 Male 132 lb 1/10/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 2/2/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 9/27/2010 78 Female 2/2/2011 Physician Japan
Primary
Concomitant
Disseminated Intravascular Coagulation Life Threatening 10/14/2010 59 Male 132 lb 2/15/2011 Physician Japan
Primary
Concomitant
Hypokalaemia Other Serious 7/5/2010 63 Female 126 lb 2/15/2011 Physician Japan
Primary
Concomitant
Hyperglycaemia Hospitalization 6/28/2010 59 Male 2/17/2011 Physician Japan
Primary
Concomitant
Blood Amylase Increased Other Serious 10/13/2010 55 Male 170 lb 2/23/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 11/1/2010 70 Male 2/24/2011 Physician Japan
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/21/2010 61 Female 2/28/2011 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 12/8/2010 73 Male 176 lb 3/7/2011 Physician Japan
Primary
Concomitant
Pneumonia Fungal Death 10/14/2010 59 Male 132 lb 3/7/2011 Physician Japan
Primary
Concomitant
Platelet Count Decreased Hospitalization 5/6/2010 68 Male 3/8/2011 Physician Japan
Primary
Concomitant
Delirium Hospitalization 10/14/2010 59 Male 132 lb 3/14/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Death 8/19/2010 70 Male 3/15/2011 Physician Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Other Serious 7/26/2010 61 Male 3/18/2011 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/7/2010 39 Male 154 lb 3/22/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Death 10/14/2010 59 Male 132 lb 3/23/2011 Physician Japan
Primary
Concomitant
Haemoglobin Decreased Other Serious 11/21/2010 54 Male 163 lb 3/28/2011 Physician Japan
Primary
Concomitant
Insomnia Hospitalization 4/23/2010 56 Female 97 lb 3/28/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 9/16/2010 75 Male 119 lb 3/30/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/2/2010 66 Male 146 lb 4/7/2011 Physician Japan
Primary
Concomitant
Blood Alkaline Phosphatase Increased Hospitalization 6/28/2010 59 Male 4/13/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 10/21/2010 61 Female 4/19/2011 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 7/5/2010 63 Female 126 lb 4/20/2011 Physician Japan
Primary
Concomitant
Sleep Disorder Hospitalization 63 Male 4/12/2011 Netherlands
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 1/19/2011 62 Male 4/27/2011 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 9/6/2010 64 Male 132 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 8/16/2010 74 Male 159 lb 4/29/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 3/29/2011 80 Male 5/9/2011 Physician Japan
Primary
Concomitant
Diarrhoea Other Serious 59 Male 5/9/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Haemorrhagic Diathesis Other Serious 11/11/2010 77 Female 108 lb 5/16/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Death 8/19/2010 70 Male 5/23/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/2/2010 66 Male 146 lb 5/24/2011 Physician Japan
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 9/16/2010 75 Male 119 lb 5/24/2011 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 12/8/2010 73 Male 176 lb 5/26/2011 Physician Japan
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 7/5/2010 63 Female 126 lb 5/26/2011 Physician Japan
Primary
Concomitant
Blood Amylase Increased Other Serious 10/13/2010 55 Male 170 lb 6/2/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Hospitalization 8/9/2010 63 Female 5/31/2011 Physician Japan
Primary
Secondary
Concomitant
Decreased Appetite Other Serious 62 Male 6/6/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cerebral Haemorrhage Life Threatening 10/16/2010 67 Male 141 lb 6/6/2011 Physician Japan
Primary
Concomitant
Anaemia Other Serious 10/8/2010 66 Male 143 lb 6/8/2011 Physician Japan
Primary
Concomitant
Sepsis Life Threatening 8/16/2010 51 Male 132 lb 6/4/2011 Other Health Professional Japan
Primary
Concomitant
Pyrexia Hospitalization 10/19/2010 44 Male 183 lb 6/14/2011 Physician Japan
Primary
Concomitant
Blood Urea Increased Other Serious 10/19/2010 57 Male 6/15/2011 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 12/28/2010 72 Male 6/17/2011 Physician Japan
Primary
Concomitant
Acne Other Serious 9/2/2010 66 Male 146 lb 6/20/2011 Physician Japan
Primary
Concomitant
Pneumonia Hospitalization 3/30/2011 58 Male 6/22/2011 Physician Japan
Primary
Concomitant
Cough Other Serious 10/8/2010 66 Male 143 lb 6/30/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Other Serious 8/19/2010 70 Male 7/4/2011 Physician Japan
Primary
Concomitant
Pleural Effusion Hospitalization 5/6/2010 68 Male 7/4/2011 Physician Japan
Primary
Concomitant
Metastases To Bone Death 1/19/2011 62 Male 6/27/2011 Physician Japan
Primary
Concomitant
Agitation Hospitalization 10/14/2010 59 Male 132 lb 7/18/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 3/31/2011 76 Female 128 lb 7/25/2011 Physician Japan
Primary
Concomitant
Anal Abscess Other Serious 8/16/2010 51 Male 132 lb 7/26/2011 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Other Serious 10/18/2010 44 Male 183 lb 8/2/2011 Physician Japan
Primary
Concomitant
Dyspnoea Other Serious 8/19/2010 70 Male 8/12/2011 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 11/21/2010 52 Female 115 lb 8/16/2011 Physician Japan
Primary
Concomitant
Neoplasm Progression Other Serious 3/23/2011 59 Male 134 lb 8/16/2011 Physician Japan
Primary
Concomitant
General Physical Health Deterioration Life Threatening 8/16/2010 51 Male 132 lb 8/25/2011 Physician Japan
Primary
Concomitant
Lymphocyte Count Increased Death 5/31/2010 65 Male 128 lb 9/6/2011 Physician Japan
Primary
Secondary
Concomitant
Haemoglobin Decreased Hospitalization 6/23/2010 59 Male 9/26/2011 Physician Japan
Primary
Concomitant
Blood Lactate Dehydrogenase Increased Other Serious 3/30/2011 58 Male 10/4/2011 Physician Japan
Primary
Concomitant
Bone Marrow Failure Hospitalization 6/20/2011 71 Male 10/20/2011 Physician Japan
Primary
Concomitant
Cough Other Serious 9/2/2010 66 Male 146 lb 10/31/2011 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Hospitalization 6/20/2011 71 Male 11/22/2011 Physician Japan
Primary
Concomitant
Skin Disorder Other Serious 11/21/2010 52 Female 115 lb 11/23/2011 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Other Serious 7/9/2010 51 Male 11/29/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 3/23/2011 59 Male 134 lb 12/2/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 7/9/2010 51 Male 12/7/2011 Other Health Professional Japan
Primary
Concomitant
Haemoglobin Decreased Death 1/19/2011 62 Male 12/13/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 10/18/2010 44 Male 183 lb 12/15/2011 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 8/9/2010 63 Female 12/21/2011 Physician Japan
Primary
Secondary
Concomitant
Lymphocyte Count Increased Death 5/31/2010 65 Male 128 lb 12/26/2011 Physician Japan
Primary
Secondary
Concomitant
Accident Death 8/17/2010 72 Male 154 lb 1/18/2012 Physician Japan
Primary
Concomitant
Pneumonia Bacterial Hospitalization 6/20/2011 71 Male 2/6/2012 Physician Japan
Primary
Concomitant
Neoplasm Malignant Other Serious 10/5/2010 64 Male 119 lb 2/6/2012 Physician Japan
Primary
Concomitant
Hyperkalaemia Hospitalization 9/15/2011 69 Male 112 lb 2/29/2012 Physician Japan
Primary
Concomitant
C-reactive Protein Increased Other Serious 3/23/2011 59 Male 134 lb 3/27/2012 Physician Japan
Primary
Concomitant
Liver Disorder Other Serious 6/2/2010 45 Male 4/5/2012 Physician Japan
Primary
Secondary
Concomitant
Hyperkalaemia Other Serious 9/15/2011 69 Male 112 lb 5/30/2012 Physician Japan
Primary
Concomitant
Metastatic Renal Cell Carcinoma Hospitalization 10/8/2010 74 Male 5/30/2012 Japan
Primary
Secondary
Concomitant
Lung Disorder Hospitalization 4/16/2012 75 Female 6/12/2012 Physician Japan
Primary
Secondary
Concomitant
Neoplasm Malignant Death 7/17/2010 67 Male 6/15/2012 Physician Japan
Primary
Concomitant
Lymphadenopathy Hospitalization 11/1/2010 70 Female 7/17/2012 Physician Japan
Primary
Concomitant
Cardiac Failure Hospitalization 12/16/2010 75 Male 8/6/2012 Physician Japan
Primary
Concomitant
Productive Cough Hospitalization 4/10/2012 75 Female 8/14/2012 Physician Japan
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 6/2/2010 45 Male 172 lb 6/13/2013 Physician Jp
Primary
Secondary
Concomitant
Pneumonia Death 9/27/2010 79 Female 3/12/2013 Physician Jp
Primary
Concomitant
Sepsis Other Serious 10/8/2010 74 Male 9/6/2012 Physician Jp
Primary
Secondary
Concomitant
Sepsis Other Serious 10/8/2010 74 Male 12/3/2012 Physician Jp
Primary
Secondary
Concomitant
Stomatitis Death 5/24/2010 54 Male 10/25/2012 Other Health Professional Jp
Primary
Concomitant
Pneumonia Aspiration Hospitalization 8/27/2010 78 Male 112 lb 12/3/2012 Physician Jp
Primary
Concomitant
Renal Failure Acute Death 8/10/2010 72 Male 121 lb 6/27/2013 Physician Jp
Primary
Concomitant
Lymphocyte Count Decreased Other Serious 58 Male 3/7/2013 Physician Jp
Primary
Concomitant

Drug Data