Insulin combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rheumatoid Arthritis Hospitalization 3/15/2000 56 Male 265 lb 1/19/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2003 76 Female 201 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 1/23/2006 Physician United States
Primary
Concomitant
Urticaria Required Intervention 6/28/2005 Male 168 lb Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 7/5/2004 59 Female 2/8/2006 Physician Japan
Primary
Concomitant
Subcutaneous Haematoma Hospitalization 6/15/2005 66 Male 198 lb 2/9/2006 Poland
Primary
Concomitant
Interacting
Weight Increased Hospitalization 1/1/1997 Male 3/2/2006 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 2/1/2004 42 Female 140 lb 12/27/2005 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Hospitalization 1/1/2003 67 Female 230 lb 12/27/2005 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 11/29/2005 89 Male 3/29/2006 Japan
Primary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/3/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 79 Female 4/12/2006 United States
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/13/2006 Other Health Professional Netherlands
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/20/2006 Physician United States
Primary
Concomitant
Rash Other Serious 2/1/2006 70 Male 4/7/2006 Physician United States
Primary
Concomitant
Hypoglycaemia Hospitalization 3/17/2006 46 Female 4/17/2006 Other Health Professional Netherlands
Primary
Concomitant
Vitamin B12 Deficiency Hospitalization 1/1/2003 76 Female 201 lb 4/27/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Life Threatening 10/20/2004 72 Male 187 lb 5/11/2006 Physician India
Primary
Concomitant
Drug Effect Decreased 10/1/2005 63 Male 240 lb 4/3/2006 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 7/1/2005 57 Female 7/19/2006 Consumer United States
Primary
Concomitant
Neuromuscular Block Prolonged Other Serious 78 Female 152 lb 7/28/2006 Physician Canada
Primary
Secondary
Concomitant
Vomiting Disability 8/26/2006 54 Female 9/20/2006 Physician Philippines
Primary
Concomitant
Vomiting Disability 8/26/2006 54 Female 9/22/2006 Physician Philippines
Primary
Concomitant
Death Death 10/17/2006 71 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Nausea Other Serious 11/14/2006 71 Female 1/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 8/15/2006 Male 243 lb 8/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/9/2002 65 Male 254 lb 3/3/2005 United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 80 Female 2/12/2007 Poland
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 2/17/2007 82 Female 3/6/2007
Primary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 4/24/2007 72 Male 152 lb 5/11/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 3/4/2006 56 Female 120 lb 12/13/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/26/2007 68 Female 150 lb 7/26/2007 India
Primary
Concomitant
Blood Disorder 1/11/2007 Male 170 lb 7/26/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 8/1/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 6/26/2007 68 Female 150 lb 8/23/2007 India
Primary
Concomitant
Weight Increased Other Serious 7/1/2007 Female 115 lb 9/11/2007 United States
Primary
Secondary
Concomitant
Nasopharyngitis Other Serious 1/1/2004 61 Male 10/1/2007 Lawyer Brazil
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 6/26/2007 68 Female 150 lb 10/11/2007 India
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 1/6/2007 60 Male 10/12/2007 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 10/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 10/25/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/21/2006 60 Male 10/29/2007 United States
Primary
Secondary
Concomitant
Sleep Disorder Hospitalization 6/1/2005 62 Male 11/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Other Serious 3/27/2002 44 Female 250 lb 11/26/2007 Physician United States
Primary
Concomitant
Tachycardia Hospitalization Female 12/5/2007 Brazil
Primary
Concomitant
Dyspnoea Hospitalization 4/24/2007 72 Male 152 lb 12/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 6/25/2007 Male 118 lb 1/16/2008 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 2/8/2008 Sweden
Primary
Concomitant
Haemoglobin Decreased Other Serious 10/30/2007 Male 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 9/1/2007 Female 157 lb 2/15/2008 Brazil
Primary
Concomitant
Epistaxis Life Threatening 1/1/2007 76 Male 186 lb 2/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Other Serious 9/1/2007 Female 157 lb 2/25/2008 Brazil
Primary
Concomitant
Weight Decreased 3/1/2007 69 Male 292 lb 1/10/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 3/7/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 3/28/2008 Sweden
Primary
Concomitant
Dyspepsia Other Serious 1/1/2006 77 Female 154 lb 4/8/2008 Consumer Australia
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/18/2008 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 8/30/2005 Male 139 lb 4/22/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 4/30/2008 United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 7/25/2007 Male 287 lb 5/1/2008 Consumer Brazil
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/9/2008 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 5/15/2008 United States
Primary
Concomitant
Hypoglycaemia Hospitalization 6/8/2007 Female 5/28/2008 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/15/2008 Female 140 lb 5/30/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 86 Male 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 86 Male 6/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 8/30/2005 Male 139 lb 6/27/2008 United States
Primary
Concomitant
Transaminases Increased Other Serious 6/3/2008 79 Female 7/7/2008 Consumer Italy
Primary
Concomitant
Vomiting Hospitalization 69 Female 7/16/2008 Other Health Professional Australia
Primary
Secondary
Concomitant
Nausea 2/27/2008 Female 8/27/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased 7/1/2008 Male 8/27/2008 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 8/6/2007 50 Male 9/29/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/4/2005 Male 225 lb 10/17/2008 Lawyer United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 4/4/2005 Male 225 lb 10/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/24/2008 Consumer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 12/2/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 11/2/2008 70 Male 235 lb 11/30/2008 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 12/7/2008 72 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 1/14/2009 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 10/1/2008 Male 152 lb 1/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 1/28/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Congenital Anomaly 12/30/2007 Female 9 lb 1/30/2009 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/21/2009 Male 174 lb 2/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 152 lb 2/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sudden Death Death 12/7/2008 72 Male 2/13/2009 Physician United Kingdom
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 2/16/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Congenital Anomaly 12/30/2007 Female 9 lb 2/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 3/2/2009 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/16/2009 United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 6/1/2003 73 Female 3/20/2009 United States
Primary
Secondary
Concomitant
Respiratory Distress Congenital Anomaly 12/30/2007 Female 9 lb 3/27/2009 Pharmacist United States
Primary
Secondary
Concomitant
Sudden Death Death 12/7/2008 Male 245 lb 3/30/2009 Physician United Kingdom
Primary
Concomitant
Spinal Osteoarthritis Other Serious 1/1/2004 84 Female 157 lb 4/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2005 69 Male 12/4/2008 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 8/3/2003 Male 139 lb 6/23/2009 Physician Sweden
Primary
Secondary
Concomitant
Hyperglycaemic Hyperosmolar Nonketotic Syndrome Other Serious 4/5/2004 60 Female 180 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/1/2001 53 Female 211 lb 9/21/2009 Other Health Professional United States
Primary
Concomitant
Thrombotic Thrombocytopenic Purpura Other Serious 9/8/2009 66 Female 229 lb 10/1/2009 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 10/23/2009 United Kingdom
Primary
Concomitant
Myositis Other Serious 8/11/2009 53 Male 10/30/2009 Physician Spain
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/10/2007 73 Male 11/4/2009 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/2/2009 United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 10/21/2008 72 Female 11/10/2009
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 11/18/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 12/1/2009 Lawyer United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Sudden Death Death 12/7/2008 Male 245 lb 1/26/2010 Physician United Kingdom
Primary
Concomitant
Vascular Graft Other Serious 1/1/1996 Male 206 lb 1/29/2010 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 73 Male 152 lb 2/10/2010 Lawyer United States
Primary
Concomitant
Sopor Hospitalization 12/29/2009 80 Female 2/18/2010 Pharmacist Italy
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Overdose Other Serious 5/28/2006 Male 201 lb 3/8/2010 Physician Italy
Primary
Secondary
Concomitant
Visual Acuity Reduced Death 3/14/2008 80 Female 181 lb 3/3/2010 Consumer United States
Primary
Concomitant
Overdose Hospitalization 5/28/2006 Male 201 lb 3/11/2010 Physician Italy
Primary
Secondary
Concomitant
Sopor Hospitalization 12/29/2009 80 Female 3/30/2010 Pharmacist Italy
Primary
Secondary
Concomitant
Sopor Hospitalization 12/29/2009 80 Female 4/8/2010 Pharmacist Italy
Primary
Secondary
Concomitant
Vascular Graft Other Serious 1/1/1996 69 Male 206 lb 4/13/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 4/20/2010 Other Health Professional Norway
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Middle Insomnia Hospitalization 4/8/2010 75 Male 4/19/2010 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 53 Female 211 lb 7/7/2010 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 12/25/2007 56 Female 181 lb 7/17/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 8/12/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 73 Male 152 lb 9/22/2010 Lawyer United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper-airway Cough Syndrome Female 10/13/2010 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 10/1/2009 70 Female 11/18/2010 Physician United States
Primary
Secondary
Concomitant
Hypomagnesaemia Hospitalization 3/1/2008 57 Male 12/21/2010 Other Health Professional Norway
Primary
Concomitant
Renal Failure Acute Hospitalization 61 Male 12/22/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 12/20/2010 76 Male 12/24/2010 Consumer United States
Primary
Concomitant
Vascular Graft Occlusion Other Serious 2/1/2008 53 Male 203 lb 12/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myositis Other Serious 8/11/2009 52 Male 2/3/2011 Physician Spain
Primary
Concomitant
Duodenal Scarring Other Serious 61 Male 2/8/2011 Other Health Professional Netherlands
Primary
Secondary
Concomitant

Drug Data