Insulin Glargine combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Myocardial Infarction Life Threatening 8/30/2005 Male 139 lb 1/17/2006 United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 2/1/2005 62 Female 90 lb 12/21/2005 Consumer United States
Primary
Concomitant
Respiratory Arrest Hospitalization 4/11/2005 27 Male 243 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 4/20/2006 74 Male 260 lb 5/5/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 3/21/2006 63 Female 220 lb 5/12/2006 United States
Primary
Secondary
Concomitant
Retinitis Pigmentosa Other Serious 55 Female 5/16/2006 Other Health Professional United Kingdom
Primary
Concomitant
Subdural Haematoma Death 4/30/2006 34 Male 5/22/2006 United States
Primary
Concomitant
Vomiting Hospitalization 6/1/2006 64 Female 6/15/2006 Consumer Argentina
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 4/30/2006 34 Male 205 lb 6/29/2006 United States
Primary
Concomitant
Adenocarcinoma Other Serious 4/24/2006 74 Male 7/6/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 4/24/2006 74 Male 7/12/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Transurethral Prostatectomy Other Serious 4/24/2006 74 Male 8/17/2006 Other Health Professional Ireland
Primary
Secondary
Concomitant
Toxic Induced Encephalopathy Hospitalization 12/18/2005 74 Male 206 lb 10/31/2006 United States
Primary
Secondary
Concomitant
Blood Sodium Decreased Other Serious 68 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Acute Myeloid Leukaemia Hospitalization 10/6/2006 66 Male 375 lb 11/30/2006 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 2/19/2007 Pharmacist France
Primary
Concomitant
Vomiting Life Threatening 3/3/2007 72 Female 4/2/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Pharyngeal Oedema Other Serious 8/1/2007 74 Female 9/13/2007 Other Health Professional United Kingdom
Primary
Concomitant
Peritoneal Haemorrhage Hospitalization 7/24/2007 Male 9/21/2007 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/14/2005 52 Female 11/5/2007 Other Health Professional Latvia
Primary
Secondary
Concomitant
Vomiting Life Threatening 3/3/2007 72 Female 12/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/31/2007 76 Male 2/25/2008 Other Health Professional France
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 7/11/2008 Female 7/22/2008 Physician Denmark
Primary
Concomitant
Pain In Extremity Hospitalization 7/1/2008 Female 8/28/2008 Physician Denmark
Primary
Concomitant
Vomiting Life Threatening 2/10/2007 72 Female 12/1/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 10/1/2008 70 Female 132 lb 12/4/2008 Physician Australia
Primary
Concomitant
Pain In Extremity Other Serious Female 143 lb 1/9/2009 Physician France
Primary
Concomitant
Gastroenteritis Hospitalization 10/27/2008 64 Male 2/25/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/27/2009 54 Female 3/5/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/27/2009 55 Female 3/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Osteomyelitis Other Serious 2/16/2009 Male 222 lb 4/1/2009 Consumer United Kingdom
Primary
Concomitant
Thrombosis Disability 3/14/2009 58 Male 238 lb 4/15/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 3/10/2009 Female 250 lb 5/8/2009 Consumer United States
Primary
Concomitant
Nausea Hospitalization 10/1/2008 70 Female 132 lb 5/21/2009 Physician Australia
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 1/27/2009 54 Female 6/22/2009 Physician Switzerland
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 3/10/2009 Female 250 lb 6/30/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/27/2009 54 Female 7/6/2009 Physician Switzerland
Primary
Secondary
Concomitant
Abortion Spontaneous Other Serious 3/10/2009 Female 250 lb 8/28/2009 Consumer United States
Primary
Concomitant
Syncope Hospitalization 4/13/2008 67 Male 278 lb 10/8/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 15 Female 10/12/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 15 Female 10/16/2009 Physician United States
Primary
Concomitant
Blood Glucose Increased Other Serious Male 225 lb 10/27/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Acute Hospitalization 7/20/2009 74 Male 11/6/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Peripheral Ischaemia Other Serious 1/1/2007 68 Female 254 lb 12/29/2009 Lawyer United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 7/1/2009 Female 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 51 Female 182 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Hydrocephalus Hospitalization 1/1/2009 Female 1/24/2010 United States
Primary
Concomitant
Vomiting Hospitalization 1/17/2010 65 Female 200 lb 2/12/2010 Pharmacist Canada
Primary
Concomitant
Pain In Extremity Other Serious 2/1/2010 Female 248 lb 2/17/2010 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious Male 180 lb 3/10/2010 Consumer United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/20/2010 72 Male 156 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/20/2010 72 Male 156 lb 3/30/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/28/2007 60 Male 4/6/2010 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 12/18/2005 74 Male 205 lb 4/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious 2/23/2010 61 Male 180 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Pyelonephritis Hospitalization 4/30/2010 55 Female 183 lb 6/7/2010 Physician Spain
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process 3/1/2008 68 Male 120 lb 7/21/2010 Consumer United States
Primary
Concomitant
Headache Female 270 lb 7/22/2010 Consumer United States
Primary
Concomitant
Social Avoidant Behaviour Other Serious 4/3/2008 58 Male 8/13/2010 Lawyer United States
Primary
Concomitant
Death Death 7/15/2010 64 Male 218 lb 8/17/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Arrhythmia Death 7/15/2010 64 Male 218 lb 8/27/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/1/2004 39 Female 290 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/24/2010 66 Female 166 lb 9/8/2010 Physician Sweden
Primary
Secondary
Abortion Spontaneous Other Serious 3/10/2009 40 Female 250 lb 9/16/2010 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 2/23/2010 61 Male 180 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Hospitalization 9/13/2010 59 Male 186 lb 9/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 9/30/2010 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/24/2010 65 Female 10/7/2010 Physician Sweden
Primary
Secondary
Rheumatoid Arthritis Other Serious 6/22/2010 63 Male 225 lb 10/12/2010 Physician Australia
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 8/24/2010 65 Female 10/14/2010 Physician Sweden
Primary
Secondary
Wheelchair User Other Serious 1/1/2004 57 Male 174 lb 10/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 20 Male 10/20/2010 Physician Spain
Primary
Concomitant
Vomiting Other Serious 20 Male 10/26/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/15/2010 63 Female 337 lb 10/26/2010 Physician Japan
Primary
Concomitant
Nausea 5/26/2009 70 Female 270 lb 10/26/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 10/27/2010 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Hospitalization 8/24/2010 65 Female 166 lb 11/1/2010 Physician Sweden
Primary
Secondary
Vomiting Hospitalization 9/15/2010 63 Female 337 lb 11/18/2010 Physician Japan
Primary
Concomitant
Metabolic Acidosis Hospitalization 10/6/2010 Female 11/9/2010 Other Health Professional
Primary
Concomitant
Hepatitis Cholestatic Other Serious 10/12/2010 74 Male 11/30/2010 Physician Italy
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/6/2010 61 Male 254 lb 12/8/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 3/10/2009 40 Female 250 lb 8/28/2009 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 2/23/2010 61 Male 180 lb 4/12/2010 Physician United States
Primary
Secondary
Concomitant
Sinusitis 12/16/2010 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 9/1/2010 65 Male 12/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Reaction 1/21/2010 12/17/2010 Consumer United States
Primary
Concomitant
Pruritus 9/16/2009 12/19/2010 Consumer United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/6/2010 61 Male 254 lb 12/21/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Musculoskeletal Stiffness 12/23/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 5/7/2005 58 Male 174 lb 12/24/2010 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization Female 12/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2010 70 Male 12/29/2010 Physician France
Primary
Concomitant
Cellulitis Other Serious 2/1/2008 61 Female 247 lb 1/28/2011 Other Health Professional United States
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/6/2010 61 Male 254 lb 1/26/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Other Serious 1/1/1984 74 Male 2/3/2011 Lawyer United States
Primary
Secondary
Concomitant
Intervertebral Disc Degeneration Hospitalization 5/7/2005 58 Male 174 lb 2/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/18/2011 Consumer United Kingdom
Primary
Concomitant
Diarrhoea Other Serious Female 107 lb 2/22/2011 Physician United States
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Somnambulism Other Serious 10/1/2010 66 Male 159 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Concomitant
Poor Peripheral Circulation Hospitalization 1/1/2010 65 Male 143 lb 2/23/2011 Consumer Mexico
Primary
Concomitant
Pancreatic Carcinoma Other Serious 7/26/2010 61 Male 254 lb 2/28/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Gastroenteritis Hospitalization 10/27/2008 64 Male 3/10/2011 Physician Ireland
Primary
Secondary
Concomitant
Depression Other Serious 3/20/2009 53 Female 3/10/2011 Lawyer United States
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 1/1/2010 61 Male 3/23/2011 Physician Spain
Primary
Concomitant
Blood Amylase Increased Hospitalization 9/8/2010 58 Female 3/25/2011 Other Health Professional France
Primary
Secondary
Concomitant
Hypoglycaemia Life Threatening 3/21/2011 82 Female 198 lb 4/4/2011 Physician United Kingdom
Primary
Concomitant
Herpes Simplex Serology Positive Other Serious 5/7/2005 58 Male 174 lb 4/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 3/31/2011 31 Female 4/13/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 3/31/2011 31 Female 4/27/2011 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hyperglycaemia Hospitalization 4/16/2011 63 Male 5/4/2011 Pharmacist Canada
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 3/31/2011 31 Female 4/29/2011 Pharmacist Denmark
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/1/2011 52 Male 8/24/2011 Physician France
Primary
Concomitant
Pancreatic Carcinoma Other Serious 2/1/2011 52 Male 194 lb 8/26/2011 Physician France
Primary
Concomitant
Retinal Detachment Other Serious 1/1/2008 67 Female 9/1/2011 Consumer Mexico
Primary
Concomitant
Pemphigoid Other Serious 71 Male 154 lb 9/22/2011 Physician Brazil
Primary
Concomitant
Cholecystitis Acute Hospitalization 11/3/2010 80 Male 159 lb 9/29/2011 Physician France
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2011 64 Male 328 lb 10/10/2011 Physician United Kingdom
Primary
Concomitant
Cholelithiasis Hospitalization 8/28/2011 82 Female 11/21/2011 Other Health Professional France
Primary
Secondary
Concomitant
Uveitis Other Serious 66 Female 136 lb 11/23/2011 Physician Brazil
Primary
Concomitant
Injection Site Abscess Other Serious 12/27/2011 Physician United States
Primary
Concomitant
Acute Pulmonary Oedema Life Threatening 12/10/2011 65 Female 238 lb 12/30/2011 Physician France
Primary
Concomitant
Spinal Disorder Hospitalization 10/17/2011 72 Male 161 lb 1/18/2012 Physician France
Primary
Concomitant
Drug Ineffective Hospitalization 10/17/2011 72 Male 161 lb 1/23/2012 Physician France
Primary
Concomitant
Cardiac Failure Death 12/10/2011 65 Female 238 lb 2/20/2012 Physician France
Primary
Concomitant
Viral Pericarditis Hospitalization 2/20/2011 62 Male 245 lb 2/21/2012 Physician France
Primary
Secondary
Concomitant
Dyspnoea Other Serious 2/27/2012 42 Female 183 lb 2/28/2012 Consumer United States
Primary
Concomitant
Respiratory Rate Decreased Other Serious 2/27/2012 42 Female 183 lb 3/30/2012 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 8/1/2011 64 Male 324 lb 4/13/2012 Physician United Kingdom
Primary
Concomitant
Fatigue Hospitalization 1/1/2012 65 Male 198 lb 4/23/2012 Physician Singapore
Primary
Concomitant
Pharyngeal Oedema Hospitalization 1/1/2012 65 Male 198 lb 4/25/2012 Physician Singapore
Primary
Concomitant
Sudden Death Death 5/6/2012 83 Female 169 lb 5/16/2012 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 5/6/2012 83 Female 169 lb 5/23/2012 Other Health Professional United States
Primary
Concomitant
Acute Pulmonary Oedema Hospitalization 12/10/2011 65 Male 238 lb 5/29/2012 Physician France
Primary
Concomitant
Abnormal Dreams 1/1/2011 56 Male 298 lb 6/5/2012 Consumer United States
Primary
Concomitant
Abnormal Dreams Male 298 lb 6/5/2012 Consumer United States
Primary
Concomitant
Sudden Death Death 5/6/2012 83 Female 169 lb 6/7/2012 Physician United States
Primary
Concomitant
Viral Pericarditis Hospitalization 2/20/2011 62 Male 234 lb 6/7/2012 Physician France
Primary
Secondary
Concomitant
Cholecystitis Acute Hospitalization 11/3/2010 80 Male 159 lb 6/19/2012 Physician France
Primary
Concomitant
Asthenia Hospitalization 1/1/2008 61 Female 143 lb 7/2/2012 Consumer Brazil
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2011 56 Male 306 lb 8/13/2012 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 73 Female 11/2/2012 Other Health Professional Es
Primary
Concomitant
Weight Gain Poor Other Serious 12/2011 Female 107 lb 10/5/2012 Physician Us
Primary
Concomitant
Nausea Hospitalization 82 Male 9/19/2012 Physician Us
Primary
Secondary
Concomitant
Peritonitis Hospitalization 2/7/2011 61 Female 198 lb 9/11/2012 Physician Ro
Primary
Concomitant
Generalised Anxiety Disorder Hospitalization 8/20/2012 57 Female 95 lb 9/26/2012 Physician Us
Primary
Secondary
Concomitant

Drug Data