Ibuprofen combined with Melatonin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Mental Status Changes Life Threatening 11/29/2005 Female 126 lb 2/13/2006 United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 3/12/2006 53 Female 3/24/2006 Physician United States
Primary
Concomitant
Respiratory Failure Death 9/13/2005 48 Male 146 lb 3/31/2006 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 5/28/2006 Female 180 lb 7/20/2006 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Life Threatening 3/13/2006 53 Female 146 lb 8/7/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 9/13/2006 52 Male 159 lb 10/2/2006 United States
Primary
Concomitant
Urinary Incontinence 1/1/2007 55 Female 140 lb 10/5/2007 Consumer United States
Primary
Concomitant
Accidental Exposure 8/31/2007 Female 182 lb 12/14/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/1995 Female 110 lb 1/11/2008 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2006 Male 155 lb 3/5/2008 Consumer United States
Primary
Concomitant
Vomiting Projectile Hospitalization 7/1/2005 1 Female 3/31/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization Female 4/30/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Haemorrhage Hospitalization 7/31/2008 Male 178 lb 9/16/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased 48 Female 169 lb 12/18/2008 Consumer United States
Primary
Concomitant
Paralysis Other Serious 9/1/2008 Female 196 lb 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Rash Other Serious 10/1/2008 Female 196 lb 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Surgery Other Serious 3/19/2009 Female 4/1/2009 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 10/7/2008 30 Female 192 lb 3/26/2009 Physician United States
Primary
Concomitant
Surgery Other Serious 3/19/2009 Female 5/8/2009 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 3/26/2009 Female 163 lb 5/8/2009 Consumer United States
Primary
Concomitant
Flushing Male 5/27/2009 United States
Primary
Concomitant
Toothache Other Serious 1/1/2008 Female 150 lb 9/9/2009 Other Health Professional United States
Primary
Concomitant
Incorrect Dose Administered 8/31/2007 Female 182 lb 9/12/2009 Consumer United States
Primary
Concomitant
Vomiting Projectile Hospitalization 1/6/1996 Female 9/18/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Other Serious 8/25/2003 46 Male 200 lb 9/23/2009 United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/4/2009 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 11/16/2009 Pharmacist United States
Primary
Concomitant
Diverticulitis Other Serious 5/1/2009 Female 141 lb 11/19/2009 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/11/2010 Pharmacist United States
Primary
Concomitant
Skin Ulcer Other Serious 4/1/2007 Female 210 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Throat Irritation Other Serious 1/1/2005 Female 153 lb 1/21/2010 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 1/30/2010 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/3/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 Female 153 lb 2/8/2010 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/12/2010 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Life Threatening 1/15/2010 Male 2/19/2010 United States
Primary
Secondary
Concomitant
Rash 10/21/2008 15 Male 100 lb 11/18/2008 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 12/18/2009 15 Female 108 lb 3/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Other Serious 2/1/2010 Female 250 lb 3/8/2010 Consumer United States
Primary
Concomitant
Tremor Other Serious 12/18/2009 15 Female 108 lb 3/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Impairment Other Serious Female 135 lb 5/4/2010 Consumer United States
Primary
Concomitant
Vision Blurred 2/23/2010 73 Male 5/11/2010 Physician
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2010 47 Female 150 lb 5/26/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 6/11/2010 United States
Primary
Concomitant
Suicidal Ideation Other Serious 1/1/2010 47 Female 155 lb 6/22/2010 Physician United States
Primary
Concomitant
Pulmonary Haemorrhage Life Threatening 12/18/2009 61 Male 185 lb 6/25/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 43 Male 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 7/27/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 43 Male 8/17/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2005 43 Male 8/20/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 8/20/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 4/1/2007 37 Female 210 lb 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 9/19/2010 55 Female 194 lb 9/27/2010 Consumer United States
Primary
Concomitant
Hypersensitivity Other Serious 9/1/2010 46 Female 175 lb 9/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 10/1/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2005 43 Male 10/29/2010 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/2005 64 Female 153 lb 12/2/2010 United States
Primary
Concomitant
Skin Ulcer Other Serious 4/1/2007 37 Female 210 lb 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/26/2008 43 Female 204 lb 1/28/2011 Consumer United States
Primary
Concomitant
Glossodynia 13 Female 11/23/2010 Pharmacist United States
Primary
Concomitant
Hypersensitivity Other Serious 9/1/2010 46 Female 175 lb 2/22/2011 Physician United States
Primary
Secondary
Concomitant
Insomnia 1/1/2009 Male 280 lb 3/25/2011 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/8/2008 33 Female 134 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Nausea Female 4/1/2011 United States
Primary
Concomitant
Neutropenia Hospitalization 4/1/2010 55 Female 270 lb 4/7/2011 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2011 65 Female 4/20/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Death 4/4/2011 56 Male 249 lb 5/3/2011 Physician United States
Primary
Concomitant
Nausea Female 5/9/2011 Consumer United States
Primary
Concomitant
Gallbladder Cholesterolosis Other Serious 12/30/2008 20 Female 126 lb 5/31/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 18 Female 139 lb 6/1/2011 Physician United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Life Threatening 5/25/2011 9 Male 86 lb 6/13/2011 Physician United Kingdom
Primary
Concomitant
Fatigue 2/1/2011 58 Female 95 lb 6/15/2011 Consumer United States
Primary
Concomitant
Cardiac Arrest Other Serious 18 Female 140 lb 6/17/2011 Lawyer United States
Primary
Concomitant
Gallbladder Injury Hospitalization 3/1/2008 37 Female 165 lb 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 5/28/2011 79 Female 157 lb 6/29/2011 Consumer United States
Primary
Secondary
Concomitant
Ligament Rupture Other Serious 18 Female 140 lb 7/20/2011 Lawyer United States
Primary
Concomitant
Depression 2/1/2011 65 Female 7/22/2011 Consumer United States
Primary
Concomitant
Arthralgia 2/1/2011 58 Female 95 lb 7/27/2011 United States
Primary
Concomitant
Chest Pain Death 18 Female 140 lb 7/29/2011 Physician United States
Primary
Concomitant
Pain Other Serious 5/28/2010 66 Female 148 lb 8/2/2011 Consumer United States
Primary
Secondary
Concomitant
Ischaemic Hepatitis Hospitalization 4/4/2011 56 Male 249 lb 8/19/2011 Physician United States
Primary
Concomitant
Rash 12/1/2008 70 Female 188 lb 8/29/2011 United States
Primary
Concomitant
Perforated Ulcer Hospitalization 2/1/2011 30 Female 227 lb 8/29/2011 Physician United States
Primary
Concomitant
Incontinence Hospitalization 1/6/1996 Female 9/7/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Fatigue 2/1/2011 58 Female 95 lb 9/9/2011 United States
Primary
Concomitant
Rash Hospitalization 1/6/1996 1 Female 9/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Convulsion Other Serious 8/1/2011 10 Female 10/3/2011 Pharmacist United States
Primary
Concomitant
Anticonvulsant Drug Level Decreased Other Serious 8/1/2011 10 Female 10/21/2011 Pharmacist United States
Primary
Concomitant
Anticonvulsant Drug Level Decreased Other Serious 8/1/2011 10 Female 12/5/2011 Pharmacist United States
Primary
Concomitant
Nausea 325 lb 1/27/2012 Consumer
Primary
Concomitant
Feeling Cold 12/10/2011 49 Female 1/29/2012 Consumer United States
Primary
Concomitant
Fall Hospitalization 11/29/2011 55 Female 200 lb 2/1/2012 United States
Primary
Concomitant
Diarrhoea Male 201 lb 2/17/2012 Consumer United States
Primary
Concomitant
Drug Ineffective For Unapproved Indication 47 Female 246 lb 3/7/2012 United States
Primary
Secondary
Concomitant
Injury Hospitalization 10/28/2009 19 Female 170 lb 3/13/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Other Serious 2/20/2012 61 Female 172 lb 3/15/2012 Consumer United States
Primary
Secondary
Concomitant
Death Death 1/1/2011 55 Male 4/5/2012 Consumer United States
Primary
Concomitant
Death Death 1/1/2011 55 Female 4/9/2012 Consumer United States
Primary
Concomitant
Eyelid Ptosis Other Serious 1/3/2012 80 Male 195 lb 4/13/2012 Physician United States
Primary
Concomitant
Pneumothorax Required Intervention 75 Male 137 lb 4/6/2012 Lawyer United States
Primary
Concomitant
Cholecystitis Hospitalization 1/1/2010 45 Female 205 lb 4/20/2012 Consumer United States
Primary
Secondary
Concomitant
Anxiety Hospitalization 1/1/2010 45 Female 205 lb 4/20/2012 Consumer United States
Primary
Secondary
Concomitant
Movement Disorder Other Serious 4/12/2012 58 Female 4/24/2012 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 7/6/2009 74 Male 192 lb 5/1/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2009 19 Female 181 lb 5/25/2012 Lawyer United States
Primary
Concomitant
Morton's Neuroma Hospitalization 2/11/2012 58 Female 185 lb 6/1/2012 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 4/12/2012 58 Female 6/4/2012 Consumer United States
Primary
Secondary
Concomitant
Pelvic Mass Other Serious 1/1/2012 54 Female 6/29/2012 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2009 19 Female 181 lb 7/2/2012 Lawyer United States
Primary
Concomitant
Injection Site Pain 1/1/2007 50 Female 183 lb 7/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 1/1/2009 29 Female 181 lb 7/11/2012 Consumer United States
Primary
Concomitant
Lymphadenopathy Hospitalization 1/1/2012 54 Female 307 lb 7/19/2012 Physician United States
Primary
Concomitant
Anaemia Other Serious 9/12/2011 60 Male 174 lb 7/27/2012 Consumer Germany
Primary
Secondary
Concomitant
Insomnia 53 Female 180 lb 7/27/2012 Consumer United States
Primary
Concomitant
Perforated Ulcer Hospitalization 2/1/2011 30 Female 227 lb 8/1/2012 Physician United States
Primary
Concomitant
Injury Hospitalization 10/28/2009 19 Female 170 lb 8/3/2012 Physician United States
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization 1/6/1996 1 Female 6/20/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Thrombosis Other Serious 5/27/2006 28 Female 9/19/2012 Consumer Us
Primary
Concomitant
Thyroid Disorder 47 Female 246 lb 4/29/2013 Us
Primary
Secondary
Concomitant
Vomiting 12/2011 49 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Visual Impairment Other Serious Female 155 lb 6/6/2012 Consumer Us
Primary
Concomitant
Limb Injury 28 Female 2/26/2013 Consumer Us
Primary
Concomitant
Tachycardia Hospitalization 5/14/2009 37 Female 155 lb 10/26/2012 Consumer Us
Primary
Secondary
Concomitant
Thrombosis Hospitalization 8/16/2011 29 Female 235 lb 2/25/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 9/12/2011 60 Male 174 lb 1/24/2013 Consumer Us
Primary
Secondary
Concomitant
Tooth Infection Female 9/14/2012 Consumer Us
Primary
Concomitant
Weight Decreased Hospitalization 8/6/2012 85 Female 121 lb 9/7/2012 Pharmacist Us
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/28/2012 57 Male 250 lb 11/6/2012 Consumer Us
Primary
Secondary
Concomitant
Pneumonia Other Serious 11/5/2012 63 Female 118 lb 1/23/2013 Consumer Country Not Specified
Primary
Concomitant
Pancytopenia Other Serious 12/3/2012 85 Male 205 lb 4/30/2013 Physician Us
Primary
Concomitant
Pneumonia Death 2012 Female 128 lb 1/14/2013 Country Not Specified
Primary
Concomitant
Rash Pruritic 1/16/2013 61 Female 170 lb 1/22/2013 Consumer Us
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 2008 Female 1/30/2013 Other Health Professional Us
Primary
Concomitant
Pain 4/30/2012 49 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Soft Tissue Injury 8/22/2012 59 NotSpecified 208 lb 1/30/2013 Country Not Specified
Primary
Concomitant
Vomiting Other Serious 2005 Female 122 lb 2/19/2013 Consumer Us
Primary
Concomitant
Interacting
Vomiting Other Serious 2005 47 Female 122 lb 2/22/2013 Consumer Us
Primary
Concomitant
Interacting
Death Death 2/15/2013 60 Female 2/28/2013 Consumer Us
Primary
Concomitant
Fatigue 2/22/2013 26 Male 139 lb 3/13/2013 Consumer Us
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 3/23/2013 16 Male 113 lb 5/3/2013 Physician Us
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/11/2013 9 Male 57 lb 4/4/2013 Pharmacist Us
Primary
Concomitant
Somnolence Hospitalization 2011 Male 4/26/2013 Physician Us
Primary
Concomitant
Haemorrhage 2013 60 Male 4/25/2013 Physician Us
Primary
Secondary
Concomitant
Musculoskeletal Pain 9/16/2011 74 Female 141 lb 4/25/2013 Other Health Professional Us
Primary
Concomitant
Weight Decreased Hospitalization 2010 50 Male 10/29/2012 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2010 50 Male 12/25/2012 Physician Us
Primary
Secondary
Concomitant
Injection Site Mass 5/6/2013 40 Male 170 lb 5/24/2013 Other Health Professional Us
Primary
Concomitant
Uterine Disorder Other Serious 2012 53 Female 165 lb 6/7/2013 Consumer Us
Primary
Interacting
Pulmonary Embolism Hospitalization 1/23/2012 37 Female 320 lb 6/13/2013 Other Health Professional Us
Primary
Concomitant
Dehydration Hospitalization 9/1/2011 Female 192 lb 8/8/2013 Physician Us
Primary
Concomitant

Drug Data