Ibuprofen combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Cerebrovascular Accident Death 9/1/2005 Female 176 lb 1/13/2006 Physician United Kingdom
Primary
Concomitant
Pharyngeal Oedema Other Serious 1/10/2006 Female 280 lb 1/26/2006 Canada
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 1/27/2006 United States
Primary
Concomitant
Throat Tightness Other Serious 1/10/2006 Female 280 lb 2/3/2006 Canada
Primary
Concomitant
Pneumonia Hospitalization 12/30/2005 Female 128 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Death 12/13/2005 75 143 lb 3/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 3/22/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 12/30/2005 Female 128 lb 4/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 12/30/2005 Female 128 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 12/1/2004 Female 176 lb 5/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 6/2/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/30/2005 Female 128 lb 6/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 6/23/2006 Physician United States
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 7/11/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 12/25/2005 Female 128 lb 8/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Arterial Occlusive Disease Other Serious 6/29/2006 Male 209 lb 8/4/2006 Consumer Canada
Primary
Concomitant
Diffuse Large B-cell Lymphoma Stage Iii Other Serious 6/27/2005 Female 161 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 8/10/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 10/1/2005 Male 172 lb 9/26/2006 Physician Germany
Primary
Concomitant
Neutropenia Other Serious 3/1/2006 Female 10/12/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Bordetella Infection Hospitalization 50 Male 11/28/2006
Primary
Secondary
Concomitant
Mycosis Fungoides Other Serious 4/19/2006 Male 203 lb 12/22/2006 Physician United States
Primary
Concomitant
Sepsis Life Threatening 10/15/2005 Male 172 lb 2/5/2007 Physician Germany
Primary
Concomitant
Oesophageal Neoplasm Other Serious 9/6/2006 71 Male 154 lb 2/12/2007 Physician Belgium
Primary
Concomitant
Psoriasis Other Serious 9/30/2006 40 Female 2/13/2007
Primary
Concomitant
Psoriasis Other Serious 9/30/2006 40 Female 2/27/2007
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/29/2006 Male 209 lb 3/30/2007 Physician Canada
Primary
Concomitant
Rheumatoid Arthritis Other Serious 6/29/2006 Male 209 lb 4/20/2007 Physician Canada
Primary
Concomitant
Pancreatic Carcinoma Other Serious Female 137 lb 4/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Chronic Lymphocytic Leukaemia Other Serious 7/21/2005 Female 174 lb 5/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 8/5/2005 Female 174 lb 6/12/2007 Other Health Professional United Kingdom
Primary
Concomitant
Visual Disturbance Disability 7/1/2005 39 Female 6/26/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Disability 7/19/2005 Female 130 lb 6/26/2007 Physician United States
Primary
Concomitant
Lymphoma Required Intervention 5/25/2006 62 Female 167 lb 6/13/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 6/10/2007 Female 335 lb 10/19/2007 United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 121 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urosepsis Life Threatening 6/10/2007 Female 335 lb 12/7/2007 United Kingdom
Primary
Concomitant
Accidental Exposure 9/8/2007 Female 175 lb 12/14/2007 Consumer United States
Primary
Concomitant
Hypothermia Other Serious 10/16/2007 Male 121 lb 2/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Pain 10/1/2007 Male 206 lb 3/15/2008 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 3/11/2008 Female 153 lb 3/18/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/11/2008 Female 153 lb 3/27/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/11/2008 66 Female 153 lb 4/22/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/11/2008 Female 153 lb 5/22/2008 United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 7/6/2007 Male 115 lb 7/18/2008 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 3/11/2008 66 Female 153 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Psoriatic Arthropathy 8/1/2006 Male 154 lb 9/12/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased 3/1/2008 Female 156 lb 9/12/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2008 Female 9/12/2008 United States
Primary
Concomitant
Accidental Exposure 8/13/2008 Male 299 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/26/2008 Physician United States
Primary
Secondary
Bronchial Carcinoma Death 8/10/2008 Male 150 lb 9/30/2008 United Kingdom
Primary
Concomitant
Hodgkin's Disease Other Serious 10 Female 9/30/2008 Physician United Kingdom
Primary
Secondary
Hodgkin's Disease Other Serious 10 Female 10/2/2008 Other Health Professional United States
Primary
Secondary
Bronchial Carcinoma Death 8/10/2008 Male 150 lb 10/2/2008 United Kingdom
Primary
Concomitant
Musculoskeletal Pain 11/1/2008 Male 140 lb 12/12/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 2/14/2008 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Rheumatoid Arthritis 7/1/2008 Male 3/14/2009 United States
Primary
Secondary
Concomitant
Hodgkin's Disease Other Serious 2 Female 5/8/2009 Other Health Professional United States
Primary
Secondary
Intestinal Stoma Other Serious 6/15/2008 Male 168 lb 6/10/2009 United Kingdom
Primary
Concomitant
Intracranial Aneurysm Hospitalization 5/8/2009 52 Male 137 lb 6/15/2009 Other Health Professional Colombia
Primary
Concomitant
Myocardial Infarction Life Threatening 6/12/2008 73 7/28/2009 Physician Peru
Primary
Secondary
Concomitant
Vision Blurred Disability 7/15/2009 73 Male 176 lb 8/25/2009
Primary
Concomitant
Incorrect Dose Administered 5/22/2007 Female 170 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 9/8/2007 Female 175 lb 9/12/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 3/31/2008 Male 240 lb 9/12/2009 United States
Primary
Concomitant
White Blood Cell Count Increased 3/1/2008 Female 156 lb 9/12/2009 Physician United States
Primary
Concomitant
Injection Site Extravasation 8/13/2008 Male 299 lb 9/12/2009 Other Health Professional United States
Primary
Concomitant
Temperature Intolerance Death 6/30/2009 Female 10/15/2009 Germany
Primary
Concomitant
Skin Infection Other Serious 8/7/2008 50 Female 10/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 12/9/2007 Female 11/16/2009 Germany
Primary
Concomitant
Subarachnoid Haemorrhage Death 10/23/2008 Female 132 lb 2/1/2010 Physician China
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 6/12/2008 73 Female 163 lb 3/3/2010 Physician Peru
Primary
Secondary
Concomitant
Intestinal Stoma Other Serious 6/15/2008 Male 168 lb 3/17/2010 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 8/24/2010 67 Female 9/28/2010 Consumer United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 6/9/2010 55 Male 220 lb 10/1/2010 Physician Germany
Primary
Concomitant
Lobar Pneumonia Death 9/25/2009 70 Male 148 lb 11/24/2010 Physician United Kingdom
Primary
Concomitant
Rash 12/13/2010 Consumer United States
Primary
Concomitant
Rhinorrhoea 12/1/2009 12/16/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 3/6/2010 12/21/2010 Consumer United States
Primary
Concomitant
Injection Site Warmth 3/3/2010 12/21/2010 Consumer United States
Primary
Concomitant
Pain In Extremity 5/10/2010 12/21/2010 Physician United States
Primary
Concomitant
Urticaria 2/21/2010 12/22/2010 Consumer United States
Primary
Concomitant
Bronchitis 6/17/2010 12/22/2010 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 12/1/2010 12/26/2010 Consumer Colombia
Primary
Concomitant
Gastrointestinal Inflammation Other Serious 12/1/2010 Female 1/28/2011 Consumer Argentina
Primary
Secondary
Concomitant
Insomnia 3/30/2010 56 Female 181 lb 1/28/2011 United States
Primary
Concomitant
Subarachnoid Haemorrhage Death 10/23/2008 70 Female 132 lb 2/7/2011 Physician China
Primary
Secondary
Concomitant
Subcutaneous Abscess Hospitalization 1/1/2010 64 Female 2/11/2011 Other Health Professional Germany
Primary
Concomitant
Pruritus Other Serious Male 2/21/2011 Other Health Professional New Zealand
Primary
Concomitant
Bladder Cancer Hospitalization 71 Male 3/1/2011 Physician United Kingdom
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 10 Female 3/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/28/2011 6 Female 44 lb 6/30/2011 Physician Germany
Primary
Secondary
Concomitant
Histiocytosis Haematophagic Hospitalization 3/28/2011 6 Female 44 lb 8/2/2011 Physician Germany
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased 5/1/2011 64 Female 10/13/2011 Other Health Professional United Kingdom
Primary
Concomitant
Arthritis Other Serious 7/1/2011 49 Male 204 lb 11/23/2011 Physician United States
Primary
Concomitant
Foetal Exposure During Pregnancy Congenital Anomaly 12/28/2011 Physician United States
Primary
Concomitant
Drug Ineffective Hospitalization Male 143 lb 12/30/2011 Finland
Primary
Secondary
Concomitant
Diverticular Perforation Hospitalization 11/23/2010 Male 1/24/2012 Physician Germany
Primary
Secondary
Concomitant
Arthralgia 3/1/2011 46 Male 1/28/2012 Consumer United States
Primary
Concomitant
Vulvovaginal Pruritus 3/1/2011 50 Female 128 lb 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia 1/1/2011 45 Male 1/28/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 4/28/2011 60 Male 1/28/2012 Consumer United States
Primary
Concomitant
Arthralgia 3/10/2011 46 Male 225 lb 1/28/2012 Consumer United States
Primary
Concomitant
Rash 10/14/2011 50 Female 1/28/2012 Consumer United States
Primary
Concomitant
Increased Upper Airway Secretion 6/11/2011 65 Male 1/28/2012 Consumer United States
Primary
Concomitant
Eye Swelling 8/1/2011 50 Female 152 lb 1/31/2012 Physician United Kingdom
Primary
Concomitant
Lung Infiltration Other Serious 3/14/2011 56 Male 172 lb 2/3/2012 Physician Germany
Primary
Concomitant
Paranasal Sinus Hypersecretion 1/1/2011 58 Female 139 lb 2/10/2012 Consumer United States
Primary
Secondary
Concomitant
Pustular Psoriasis Disability 9/7/2011 51 Female 153 lb 2/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Psoriasis Disability 9/7/2011 51 Female 153 lb 2/10/2012 Other Health Professional United Kingdom
Primary
Concomitant
Abscess Hospitalization 1/3/2012 Female 196 lb 3/8/2012 Physician Germany
Primary
Concomitant
Abscess Hospitalization 1/3/2012 Female 196 lb 4/4/2012 Physician Germany
Primary
Concomitant
Arthritis Other Serious 1/1/2010 26 Female 150 lb 4/13/2012 Consumer Brazil
Primary
Secondary
Concomitant
Arthritis Other Serious 1/1/2010 26 Female 150 lb 4/24/2012 Physician Brazil
Primary
Secondary
Concomitant
Paraesthesia Other Serious 1/1/2011 48 Male 204 lb 5/1/2012 Physician United States
Primary
Concomitant
Headache 67 Female 123 lb 5/2/2012 Consumer United States
Primary
Concomitant
Rash Generalised Hospitalization 4/3/2012 55 Female 119 lb 5/8/2012 Physician Spain
Primary
Concomitant
Femur Fracture Other Serious 6/1/2011 67 Female 5/14/2012 Consumer Canada
Primary
Concomitant
Rash Generalised Other Serious 4/3/2012 55 Female 119 lb 6/22/2012 Physician Spain
Primary
Concomitant
Cholecystitis Infective Hospitalization 6/5/2012 55 Female 180 lb 7/3/2012 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2007 50 Female 183 lb 7/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2011 55 Female 7/12/2012 Consumer Germany
Primary
Concomitant
Nausea Other Serious 1/1/2012 47 Female 181 lb 7/23/2012 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 1/1/2012 65 Female 189 lb 8/9/2012 Other Health Professional United Kingdom
Primary
Concomitant
Vacterl Syndrome Congenital Anomaly NotSpecified 9/13/2013 Physician Us
Primary
Concomitant
Stress 3/10/2011 46 Male 225 lb 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Muscle Abscess Hospitalization 1/3/2012 Female 196 lb 4/29/2013 Physician De
Primary
Concomitant
Pulmonary Embolism Hospitalization 4/23/2012 Female 170 lb 8/6/2013 Physician De
Primary
Concomitant
Nasopharyngitis 4/15/2009 46 Female 10/25/2012 Other Health Professional Us
Primary
Concomitant
White Blood Cell Count Decreased 11/14/2011 48 Male 210 lb 10/24/2012 Physician Us
Primary
Concomitant
Urticaria Female 11/8/2012 Physician Us
Primary
Concomitant
Malaise 5/10/2012 61 Female 11/8/2012 Physician Us
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 11/1/2012 77 Female 154 lb 3/19/2013 Physician Nz
Primary
Concomitant
Injection Site Pain 7/7/2012 63 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Rash 2012 Female 173 lb 1/31/2013 Country Not Specified
Primary
Concomitant
Breast Cancer Female Hospitalization 8/15/2012 52 Female 1/30/2013 Physician De
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2007 Female 110 lb 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Swelling Face Other Serious 11/30/2012 66 Female 172 lb 2/28/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Swelling Other Serious 65 Female 165 lb 4/19/2013 Consumer Us
Primary
Concomitant
Bladder Cancer Hospitalization 71 Male 4/8/2013 Physician De
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/15/2012 Female 4/22/2013 Physician De
Primary
Secondary
Concomitant
Single Functional Kidney Congenital Anomaly NotSpecified 6/20/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Hospitalization 6/2013 79 Female 134 lb 6/27/2013 Physician Gb
Primary
Concomitant
Pneumonia Hospitalization 11/1/2012 61 Female 251 lb 6/28/2013 Physician Gb
Primary
Concomitant
Vomiting Projectile Hospitalization Female 176 lb 7/10/2013 Consumer Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Hospitalization 6/2013 79 Female 134 lb 7/13/2013 Other Health Professional Gb
Primary
Concomitant
Rhinorrhoea 6/2013 53 Female 8/1/2013 Other Health Professional Us
Primary
Concomitant
Renal Abscess Hospitalization 4/18/2012 38 Female 126 lb 8/17/2013 Physician Mx
Primary
Secondary
Concomitant

Drug Data