Hydroxychloroquine Sulfate combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Blood Pressure Increased Hospitalization 1/3/2006 Female 222 lb 2/14/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 1/1/2005 Female 123 lb 4/13/2006 Other Health Professional France
Primary
Concomitant
Infusion Related Reaction Hospitalization 1/3/2006 Female 222 lb 5/3/2006 Physician United States
Primary
Concomitant
Infusion Related Reaction Hospitalization 1/3/2006 Female 338 lb 6/2/2006 Physician United States
Primary
Concomitant
Vasculitic Rash Other Serious 12/18/2001 Female 118 lb 6/28/2006 Physician United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 76 Female 8/14/2006 United States
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 12/12/2005 36 Male 8/30/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Bronchospasm Hospitalization 12/12/2005 36 Male 9/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Disability 1/1/2006 47 Female 10/27/2006 Other Health Professional France
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Tuberculosis Hospitalization 7/1/2005 Male 11/16/2006 Other Health Professional Finland
Primary
Secondary
Concomitant
Hip Fracture Other Serious 1/17/2006 Female 126 lb 11/21/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prostate Cancer Other Serious 4/15/2006 Female 143 lb 12/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Cell Carcinoma Stage Unspecified Life Threatening 9/15/2006 Female 1/8/2007 Other Health Professional Australia
Primary
Concomitant
Cutaneous Lupus Erythematosus Hospitalization Female 1/19/2007 Other Health Professional France
Primary
Concomitant
Hemiplegia Hospitalization 10/1/2005 Female 3/20/2007 Physician Costa Rica
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 4/19/2007 Physician Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/5/2007 Female 99 lb 4/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Distress Hospitalization 5/1/2007 83 Female 5/23/2007 Physician Venezuela
Primary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 121 lb 5/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Blistering Other Serious Female 6/4/2007 Physician United Kingdom
Primary
Concomitant
Lung Disorder Hospitalization 4/1/2007 Female 6/5/2007 Physician Canada
Primary
Concomitant
Pustular Psoriasis Hospitalization 12/25/2006 Female 6/7/2007 Other Health Professional Australia
Primary
Concomitant
Pustular Psoriasis Hospitalization 5/21/2007 Male 6/15/2007 Physician Finland
Primary
Concomitant
Pustular Psoriasis Hospitalization 5/21/2007 Male 7/3/2007 Physician Finland
Primary
Concomitant
Pustular Psoriasis Hospitalization 12/25/2006 Female 7/16/2007 Consumer Australia
Primary
Concomitant
Anaemia Hospitalization 8/23/2006 Female 93 lb 8/3/2007 United Kingdom
Primary
Concomitant
Neoplasm Skin Other Serious 9/15/2007 Male 9/26/2007 Consumer United States
Primary
Concomitant
Basal Cell Carcinoma Other Serious 4/25/2007 75 Female 132 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Underdose Hospitalization 1/1/1996 50 Female 11/15/2007 Lawyer United States
Primary
Concomitant
Neoplasm Skin Other Serious 8/30/2007 Male 12/11/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/1996 50 Female 12/17/2007 Physician United States
Primary
Concomitant
Lower Limb Fracture Life Threatening 8/29/2007 Female 12/20/2007 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/1996 50 Female 1/9/2008 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/1996 50 Female 1/29/2008 Physician United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Other Serious 1/1/1996 50 Female 2/4/2008 Physician United States
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 11/1/2007 Male 251 lb 2/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/1996 50 Female 126 lb 2/18/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1996 50 Female 126 lb 2/21/2008 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Life Threatening 11/7/2007 Male 251 lb 2/29/2008 United Kingdom
Primary
Concomitant
Loss Of Consciousness Hospitalization 6/1/2007 Male 2/25/2008 Physician Turkey
Primary
Concomitant
Hypoglycaemia Other Serious 64 Male 3/10/2008 Other Health Professional Turkey
Primary
Concomitant
Hypoglycaemia Hospitalization 6/1/2007 64 Male 4/24/2008 Other Health Professional Turkey
Primary
Concomitant
Pneumonia Legionella Death 4/17/2008 Male 5/1/2008 Physician New Zealand
Primary
Secondary
Concomitant
Death Death 7/30/2007 Female 5/20/2008 Canada
Primary
Concomitant
Nerve Root Lesion Hospitalization 5/2/2008 34 Male 6/5/2008 Physician Finland
Primary
Concomitant
Hypoglycaemia Hospitalization 6/1/2007 62 Male 5/19/2008 United States
Primary
Concomitant
Psoriasis 12/1/2007 Male 330 lb 6/12/2008 United States
Primary
Concomitant
Sinusitis 10/1/2007 Female 150 lb 6/12/2008 United States
Primary
Concomitant
Scratch 3/1/2008 Female 301 lb 6/12/2008 United States
Primary
Concomitant
Rheumatoid Arthritis 11/1/2007 Female 195 lb 6/13/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 4/11/2008 Female 180 lb 6/13/2008 Consumer United States
Primary
Concomitant
Sneezing 5/14/2008 Female 228 lb 6/13/2008 Consumer United States
Primary
Concomitant
Nerve Root Lesion Hospitalization 5/9/2008 34 Male 6/13/2008 Physician Finland
Primary
Concomitant
Nerve Root Lesion Hospitalization 5/9/2008 34 Male 6/26/2008 Physician Finland
Primary
Concomitant
Spinal Rod Insertion Hospitalization 4/23/2007 Female 140 lb 7/8/2008 Physician United States
Primary
Concomitant
Tuberculosis Other Serious 11/1/2001 53 Female 7/18/2008 Other Health Professional United States
Primary
Concomitant
Death Other Serious 54 Female 146 lb 7/28/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Pressure Increased 6/10/2008 Male 175 lb 9/12/2008 United States
Primary
Concomitant
Pleural Effusion Other Serious 12/1/2003 Female 143 lb 11/26/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Nerve Compression Hospitalization 11/4/2004 Female 176 lb 12/2/2008 United Kingdom
Primary
Concomitant
Pleural Effusion Death 1/1/2003 47 Female 12/3/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Nodule 1/1/2005 Female 212 lb 12/8/2008 Physician United States
Primary
Concomitant
Wheezing 3/17/2008 Female 12/8/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 12/1/2007 Female 12/8/2008 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/1996 50 Female 126 lb 12/11/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria 8/28/2008 Female 12/12/2008 United States
Primary
Concomitant
Staphylococcal Skin Infection 7/1/2008 Female 220 lb 12/12/2008 Consumer United States
Primary
Concomitant
Procedural Complication Female 12/12/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 8/29/2008 Female 162 lb 12/12/2008 Consumer United States
Primary
Concomitant
Musculoskeletal Chest Pain 10/16/2008 Female 12/12/2008 United States
Primary
Concomitant
Drug Ineffective 7/1/2008 Female 157 lb 12/12/2008 United States
Primary
Concomitant
Nocardiosis Other Serious 10/1/2008 Male 222 lb 12/16/2008 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 7/1/2007 Female 2/4/2009 Germany
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 135 lb 3/6/2009 Physician United States
Primary
Secondary
Concomitant
Pseudomonas Infection Other Serious 1/27/2008 Female 139 lb 3/6/2009 Physician United States
Primary
Secondary
Concomitant
Serum Sickness Other Serious 1/26/2009 15 Female 277 lb 4/28/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy 6/29/2008 39 Female 121 lb 4/30/2009 Argentina
Primary
Secondary
Morbid Thoughts Other Serious 11/25/2008 Female 144 lb 6/1/2009 Other Health Professional Canada
Primary
Concomitant
Rash Pustular 1/1/2008 Male 6/11/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 7/1/2002 64 Female 7/8/2009
Primary
Secondary
Concomitant
Tenosynovitis Other Serious 54 Female 7/8/2009 Physician United Kingdom
Primary
Concomitant
Unevaluable Event Death 58 Female 8/14/2009 Lawyer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/16/2009 Female 8/26/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1996 50 Female 126 lb 9/8/2009 Physician United States
Primary
Secondary
Concomitant
Incorrect Dose Administered 6/16/2007 Female 210 lb 9/11/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 5/1/2007 Female 180 lb 9/11/2009 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 10/4/2007 Female 118 lb 9/12/2009 Consumer United States
Primary
Concomitant
Psoriasis 12/1/2007 Male 330 lb 9/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 4/11/2008 Female 180 lb 9/12/2009 Consumer United States
Primary
Concomitant
Rash Pustular 1/1/2008 Male 157 lb 9/19/2009 United States
Primary
Concomitant
Product Substitution Issue Disability 8/15/2009 Male 175 lb 10/1/2009 Other Health Professional United States
Primary
Concomitant
Vaginal Infection Other Serious 5/8/2009 46 Female 233 lb 10/20/2009 Other Health Professional United States
Primary
Concomitant
Tongue Eruption Hospitalization 3/1/2009 Female 141 lb 10/26/2009 Brazil
Primary
Concomitant
Stomatitis 1/31/2009 Female 12/1/2009 Consumer United States
Primary
Secondary
Concomitant
Tongue Ulceration Hospitalization 3/1/2009 Female 139 lb 12/21/2009 Brazil
Primary
Concomitant
Sepsis Death 4/17/2008 Male 1/7/2010 Physician New Zealand
Primary
Secondary
Concomitant
Mood Swings 11/30/2009 Female 1/30/2010 United States
Primary
Concomitant
Synovitis Hospitalization 2/24/2009 Female 2/15/2010 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 1/16/2010 43 Female 172 lb 2/18/2010 Consumer India
Primary
Concomitant
Headache 1/1/2009 55 Female 1/28/2010 Consumer United States
Primary
Concomitant
Urticaria Hospitalization 32 Female 4/3/2010 Hong Kong
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2009 25 Female 4/20/2010 Physician Canada
Primary
Concomitant
Impaired Healing Hospitalization 8/1/2009 60 Male 5/6/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 141 lb 5/24/2010 Brazil
Primary
Secondary
Concomitant
Peripheral Vascular Disorder Hospitalization 10/17/2009 59 Male 171 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 10/7/2008 44 Female 146 lb 7/8/2010 Lawyer Italy
Primary
Concomitant
Sinusitis Other Serious 10/7/2008 44 Female 146 lb 7/9/2010 Lawyer Italy
Primary
Concomitant
Urticaria Other Serious 9/1/2008 10/21/2010 Physician United States
Primary
Concomitant
Tooth Disorder Other Serious 3/1/2007 44 Female 146 lb 11/16/2010 Physician Italy
Primary
Concomitant
Oral Candidiasis Other Serious 10/24/2009 55 Female 180 lb 11/24/2010 Physician Pakistan
Primary
Concomitant
Pain Hospitalization 6/22/2010 67 Male 196 lb 11/29/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Injection Site Pain 10/1/2009 12/13/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 12/14/2010 Physician United States
Primary
Concomitant
Urticaria 11/20/2009 12/14/2010 Physician United States
Primary
Concomitant
Pyrexia 11/26/2009 12/14/2010 Physician United States
Primary
Concomitant
Gait Disturbance 11/1/2009 12/14/2010 Physician United States
Primary
Concomitant
Sensation Of Heaviness 8/1/2009 12/14/2010 Consumer United States
Primary
Concomitant
Injection Site Reaction 10/1/2009 12/14/2010 Consumer United States
Primary
Concomitant
Herpes Zoster 12/23/2009 12/15/2010 Consumer United States
Primary
Concomitant
Vulvovaginal Mycotic Infection 1/1/2008 12/15/2010 Physician United States
Primary
Concomitant
Injection Site Pain 11/16/2009 12/16/2010 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2000 12/16/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 1/11/2010 12/16/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 12/28/2009 12/16/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 3/8/2009 12/16/2010 Consumer United States
Primary
Concomitant
Vaginal Infection 12/27/2009 12/16/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 6/1/2009 12/17/2010 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 2/17/2010 12/19/2010 Physician United States
Primary
Concomitant
Nasopharyngitis 2/1/2010 12/19/2010 Consumer United States
Primary
Concomitant
Rash Pruritic 10/1/2004 12/19/2010 Consumer United States
Primary
Concomitant
Injection Site Pruritus 1/1/2010 12/19/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 12/19/2010 Consumer United States
Primary
Concomitant
Skin Laceration 3/20/2010 12/19/2010 Physician United States
Primary
Concomitant
Injection Site Pain 4/2/2010 12/19/2010 Consumer United States
Primary
Concomitant
Nausea 3/11/2010 12/19/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 1/15/2009 12/20/2010 Physician United States
Primary
Concomitant
Injection Site Swelling 3/8/2010 12/20/2010 Physician United States
Primary
Concomitant
Rheumatoid Arthritis 3/1/2010 12/20/2010 Physician United States
Primary
Concomitant
Injection Site Haemorrhage 3/26/2010 12/20/2010 Physician United States
Primary
Concomitant
Injection Site Rash 1/3/2010 12/21/2010 Physician United States
Primary
Concomitant
Injection Site Pain 6/22/2007 12/21/2010 Physician United States
Primary
Concomitant
Injection Site Urticaria 5/24/2010 12/22/2010 Consumer United States
Primary
Concomitant
Sinusitis 2/5/2010 12/22/2010 Consumer United States
Primary
Concomitant
Injection Site Erythema 7/11/2010 12/23/2010 Consumer United States
Primary
Concomitant
Malaise 12/23/2010 Consumer United States
Primary
Concomitant
Myalgia 8/20/2010 12/23/2010 Physician United States
Primary
Concomitant
Pruritus Generalised 7/1/2010 12/23/2010 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 2/25/2009 57 Female 172 lb 12/28/2010 Physician Australia
Primary
Concomitant

Drug Data