Hydroxychloroquine combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hiatus Hernia Other Serious 8/24/2007 Male 141 lb 1/25/2008 United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 10/1/2007 Female 1/28/2008 Physician Germany
Primary
Concomitant
Pulmonary Tuberculosis Life Threatening 2/29/2008 Female 209 lb 3/27/2008 Physician Brazil
Primary
Concomitant
Hypoglycaemic Unconsciousness Hospitalization 6/1/2007 62 Male 3/31/2008 Other Health Professional Turkey
Primary
Concomitant
Myositis Hospitalization Female 4/1/2008 Consumer United Kingdom
Primary
Concomitant
Peripheral Embolism Life Threatening 11/7/2007 Male 251 lb 4/4/2008 United Kingdom
Primary
Secondary
Concomitant
Neuralgic Amyotrophy Hospitalization 11/1/2006 50 Male 137 lb 4/11/2008 Physician Turkey
Primary
Concomitant
Pneumonia Other Serious 54 Female 146 lb 8/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Pruritic 6/7/2008 Female 152 lb 9/12/2008 United States
Primary
Concomitant
Treatment Noncompliance 1/1/2006 Female 160 lb 9/12/2008
Primary
Secondary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2008 United States
Primary
Concomitant
Skin Reaction 7/2/2008 Female 160 lb 9/12/2008 United States
Primary
Concomitant
Thyroid Neoplasm 5/1/2008 Female 235 lb 9/12/2008 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2008 Female 226 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 7/23/2008 Female 9/12/2008 United States
Primary
Concomitant
Lip Pain 4/1/2008 Female 130 lb 9/12/2008 United States
Primary
Concomitant
Road Traffic Accident 11/28/2007 Female 180 lb 9/13/2008 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 7/10/2008 Male 161 lb 10/6/2008 United Kingdom
Primary
Concomitant
Renal Failure Other Serious 5/7/2008 54 Female 146 lb 10/15/2008 Other Health Professional United Kingdom
Primary
Concomitant
Fistula Hospitalization 8/20/2008 Male 216 lb 10/29/2008 Physician Romania
Primary
Secondary
Concomitant
Renal Failure Other Serious 4/1/2003 Female 10/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 7/1/2007 Female 1/20/2009 Germany
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 128 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rheumatoid Arthritis 11/1/2007 Female 195 lb 3/13/2009 Physician United States
Primary
Concomitant
Pyrexia 11/25/2008 Female 3/14/2009 United States
Primary
Secondary
Concomitant
Pain 7/1/2007 Female 155 lb 3/14/2009 Consumer United States
Primary
Concomitant
Disseminated Tuberculosis Hospitalization Male 215 lb 3/27/2009 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/14/2008 Female 228 lb 9/12/2009 Consumer United States
Primary
Concomitant
Injection Site Pain 6/14/2008 Female 223 lb 9/12/2009 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 7/1/2008 Female 220 lb 9/12/2009 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 4/1/2008 Female 226 lb 9/12/2009 Other Health Professional United States
Primary
Concomitant
Musculoskeletal Pain Female 9/19/2009 United States
Primary
Concomitant
Lacrimation Increased 8/24/2009 Female 158 lb 9/19/2009 United States
Primary
Concomitant
Vomiting Hospitalization 7/13/2008 Male 10/13/2009 United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 11/16/2009 Male 200 lb 11/25/2009 Canada
Primary
Concomitant
Tibia Fracture Required Intervention 48 Female 6/10/2010 Physician United States
Primary
Concomitant
Psoriasis Other Serious 52 Male 6/17/2010 Other Health Professional Italy
Primary
Secondary
Lethargy 3/9/2007 53 Female 215 lb 7/9/2010 Consumer United States
Primary
Concomitant
Cervical Dysplasia Other Serious 20 Female 7/12/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Nausea 7/22/2007 67 Female 170 lb 7/14/2010 Consumer United States
Primary
Concomitant
Pain Hospitalization 6/24/2010 67 Male 196 lb 8/3/2010 Physician United Kingdom
Primary
Concomitant
Bladder Cancer Other Serious 10/20/2009 75 Male 191 lb 8/4/2010 Consumer United States
Primary
Concomitant
Strabismus Other Serious 7/1/2010 56 Female 150 lb 8/18/2010 Physician Canada
Primary
Concomitant
Squamous Cell Carcinoma Other Serious Female 9/10/2010 Consumer United States
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 72 Female 128 lb 9/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Oral Candidiasis Other Serious 55 Female 180 lb 11/15/2010 Physician Pakistan
Primary
Concomitant
Lung Disorder Other Serious 9/1/2010 53 Female 11/16/2010 Other Health Professional Canada
Primary
Concomitant
Spinal Column Stenosis Hospitalization 7/15/2010 54 Female 165 lb 11/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2010 70 Female 164 lb 12/13/2010 Physician United States
Primary
Concomitant
Nasopharyngitis 10/31/2009 12/13/2010 Consumer United States
Primary
Concomitant
Pruritus Generalised 1/1/2010 12/15/2010 Physician United States
Primary
Concomitant
Urinary Tract Infection 8/1/2009 12/17/2010 Physician United States
Primary
Concomitant
Injection Site Swelling 3/13/2009 12/19/2010 Consumer United States
Primary
Concomitant
Dysphemia 2/22/2010 12/19/2010 Consumer United States
Primary
Concomitant
Skin Papilloma 9/1/2010 12/19/2010 United States
Primary
Concomitant
Pain In Extremity 2/1/2010 12/19/2010 Physician United States
Primary
Concomitant
Sinusitis 3/27/2009 12/19/2010 Physician United States
Primary
Concomitant
Injection Site Reaction 12/26/2009 12/21/2010 Consumer United States
Primary
Concomitant
Rheumatoid Arthritis 6/26/2010 12/23/2010 Physician United States
Primary
Concomitant
Injection Site Urticaria 2/10/2010 62 Female 143 lb 1/28/2011 United States
Primary
Concomitant
Rash Pustular 10/18/2010 60 Female 135 lb 1/30/2011 Consumer United States
Primary
Concomitant
Feeling Abnormal 12/6/2010 55 Male 1/30/2011 Consumer United States
Primary
Concomitant
Urinary Incontinence Hospitalization 63 Male 2/23/2011 Physician Turkey
Primary
Concomitant
Interacting
Hypoglycaemia Hospitalization 72 Female 2/24/2011 Physician Turkey
Primary
Concomitant
Syncope Hospitalization 72 Female 2/28/2011 Other Health Professional Turkey
Primary
Concomitant
Drug Effect Decreased 1/1/2010 37 Female 3/8/2011 Physician United States
Primary
Concomitant
Neutropenic Sepsis Death 2/6/2011 60 Male 132 lb 3/15/2011 Other Health Professional United Kingdom
Primary
Secondary
Hypoglycaemia Other Serious 3/1/2011 66 Female 102 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2011 61 Female 172 lb 5/12/2011 Other Health Professional Canada
Primary
Concomitant
C-reactive Protein Increased Hospitalization 47 Female 5/12/2011 Other Health Professional Turkey
Primary
Concomitant
Skin Cancer Other Serious 10/20/2010 72 Female 8/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus Disability 7/25/2011 50 Female 198 lb 8/8/2011 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Other Serious 6/1/2011 65 Female 8/9/2011 Physician France
Primary
Secondary
Concomitant
Joint Instability Other Serious 7/25/2011 50 Female 198 lb 8/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Tympanic Membrane Disorder Hospitalization 46 Female 8/22/2011 Other Health Professional Korea, Republic Of
Primary
Concomitant
Urinary Tract Infection Disability 7/25/2011 50 Female 198 lb 8/25/2011 Other Health Professional United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 1/1/2009 63 Female 164 lb 8/31/2011 Consumer United States
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2009 63 Female 164 lb 12/2/2011 Physician United States
Primary
Concomitant
Amnesia Other Serious 11/1/2011 55 Female 12/9/2011 Physician Australia
Primary
Concomitant
Dysarthria Life Threatening 1/17/2012 54 Female 5/8/2012 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Death 5/20/2011 85 Male 5/8/2012 United Kingdom
Primary
Concomitant
Shoulder Operation Other Serious 4/27/2012 64 Male 141 lb 5/11/2012 Other Health Professional Canada
Primary
Concomitant
Rheumatoid Vasculitis Disability 12/2009 72 Male 10/2/2013 Other Health Professional Tr
Primary
Concomitant
Stress Hospitalization 3/2011 Male 188 lb 3/29/2013 Consumer Country Not Specified
Primary
Concomitant
Neutropenic Sepsis Death 2/6/2011 60 Male 8/10/2012 Other Health Professional Gb
Primary
Secondary
Treatment Noncompliance 1/5/2011 63 Female 10/23/2012 Consumer Us
Primary
Concomitant
Wrong Technique In Drug Usage Process 5/17/2011 54 Male 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Dysarthria Life Threatening 1/17/2012 54 Female 6/27/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Swelling Face Other Serious 76 Female 139 lb 11/2/2012 Consumer Ca
Primary
Secondary
Concomitant
Exposure During Pregnancy Other Serious Female 10/12/2012 Physician Fi
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 7/3/2012 88 Female 183 lb 9/12/2012 Physician Us
Primary
Concomitant
Synovitis 2011 75 Female 215 lb 9/4/2012 Consumer Us
Primary
Concomitant
Skin Reaction Other Serious 1/2012 Female 287 lb 10/9/2012 Other Health Professional Gb
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Other Serious 62 Female 9/21/2012 Physician Country Not Specified
Primary
Secondary
Sepsis Death 12/25/2010 61 Female 290 lb 10/4/2012 Physician Us
Primary
Concomitant
Synovitis Other Serious 2011 75 Female 215 lb 10/5/2012 Consumer Us
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/2011 Male 179 lb 10/22/2012 Physician Country Not Specified
Primary
Concomitant
Metrorrhagia 2011 44 Female 145 lb 10/11/2012 Consumer Us
Primary
Concomitant
Pneumonia Death Female 163 lb 10/19/2012 Other Health Professional Country Not Specified
Primary
Concomitant
Pneumonia Death Female 163 lb 8/15/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Staphylococcal Infection Hospitalization 2010 78 Female 142 lb 10/24/2012 Physician Us
Primary
Concomitant
Chest X-ray Abnormal 12/15/2011 57 Female 170 lb 10/25/2012 Physician Us
Primary
Concomitant
Rheumatoid Arthritis Other Serious Female 11/5/2012 Consumer Gb
Primary
Concomitant
Urticaria Female 11/8/2012 Physician Us
Primary
Concomitant
Tooth Infection 6/18/2012 62 Female 365 lb 11/8/2012 Consumer Us
Primary
Concomitant
Swelling 3/17/2012 46 Female 232 lb 11/8/2012 Other Health Professional Us
Primary
Concomitant
Renal Cell Carcinoma Other Serious 11/1/2012 50 Female 169 lb 12/3/2012 Physician Gb
Primary
Concomitant
Spinal Cord Disorder Hospitalization 2012 50 Female 12/14/2012 Other Health Professional Gb
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 9 Male 12/19/2012 Other Health Professional In
Primary
Secondary
Concomitant
Hirsutism Other Serious 3 Male 12/19/2012 Other Health Professional In
Primary
Secondary
Concomitant
Lower Respiratory Tract Infection Other Serious Female 12/19/2012 Other Health Professional In
Primary
Secondary
Concomitant
Spondylitis Hospitalization 6/15/2012 61 Female 1/10/2013 Physician De
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 11/1/2012 77 Female 154 lb 3/19/2013 Physician Nz
Primary
Concomitant
Septic Shock Death 10/2012 79 Female 1/8/2013 Other Health Professional Tw
Primary
Concomitant
Wound Other Serious 2010 Female 1/8/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Pulmonary Embolism Hospitalization 2012 Female 237 lb 2/27/2013 Physician Country Not Specified
Primary
Concomitant
Dizziness 5/8/2012 65 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Drug Ineffective 2009 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Weight Decreased 59 Female 2/1/2013 Consumer Country Not Specified
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 12/1/2012 57 Female 4/30/2013 Physician Country Not Specified
Primary
Concomitant
Knee Arthroplasty Other Serious 1/15/2013 45 Female 172 lb 2/5/2013 Other Health Professional Tw
Primary
Concomitant
Rash 2/2/2013 50 Female 5/10/2013 Consumer Us
Primary
Concomitant
Metamorphopsia 5/13/2012 61 Male 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Vitamin B Complex Deficiency 1/2012 36 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Wound 12/2011 Female 121 lb 1/29/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Injection Site Pain Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Skin Wound 5/2012 Female 131 lb 1/29/2013 Consumer Country Not Specified
Primary
Secondary
Concomitant
Rash 5/21/2012 78 Female 1/29/2013 Consumer Country Not Specified
Primary
Concomitant
Cystitis 6/30/2012 79 Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Pallor 11/1/2012 57 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Drug-induced Liver Injury Hospitalization 46 Female 3/27/2013 Consumer De
Primary
Secondary
Rash Pruritic 2012 62 Male 3/18/2013 Consumer Ca
Primary
Secondary
Concomitant
Menorrhagia Other Serious 1/30/2013 45 Female 4/7/2013 Physician Ca
Primary
Concomitant
Treatment Failure Other Serious NotSpecified 4/23/2013 Physician Gb
Primary
Concomitant
Coccidioidomycosis Other Serious 3/22/2013 58 Female 160 lb 4/24/2013 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization Male 7/3/2013 Physician Gb
Primary
Concomitant
Pulmonary Tuberculosis Other Serious 63 Female 5/17/2013 Other Health Professional Country Not Specified
Primary
Secondary
Mycobacterial Infection Other Serious 52 Female 5/17/2013 Other Health Professional Country Not Specified
Primary
Secondary
Insomnia Other Serious 6/12/2013 65 Female 6/21/2013 Physician Country Not Specified
Primary
Secondary
Concomitant
Aortic Dilatation Other Serious 5/21/2013 56 Male 6/27/2013 Consumer Co
Primary
Concomitant
Pruritus Generalised Other Serious 11/9/2011 40 Female 141 lb 12/11/2013 Physician Br
Primary
Secondary
Concomitant
Vomiting Projectile Hospitalization Female 176 lb 7/10/2013 Consumer Us
Primary
Secondary
Concomitant
Ischaemic Cerebral Infarction Other Serious 7/14/2013 74 Male 128 lb 7/29/2013 Consumer Br
Primary
Concomitant
Weight Decreased 2013 57 Female 8/7/2013 Physician Us
Primary
Secondary
Renal Disorder Death 7/5/2013 60 Female 182 lb 10/4/2013 Consumer Us
Primary
Concomitant
Stomatitis Other Serious 3/22/2013 65 Female 151 lb 8/14/2013 Consumer Us
Primary
Secondary
Concomitant
Peritonitis Other Serious 7/13/2013 52 Male 9/24/2013 Physician Gb
Primary
Concomitant
Sepsis Hospitalization 70 Female 9/5/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious NotSpecified 9/16/2013 Other Health Professional My
Primary
Secondary
Lumbar Vertebral Fracture Other Serious 7/8/2013 72 Female 139 lb 9/19/2013 Consumer Country Not Specified
Primary
Concomitant

Drug Data