Hydromorphone combined with Oxycodone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sedation Hospitalization 56 Male 12/18/2008 Physician United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 23 Male 6/4/2009 Consumer United States
Primary
Secondary
Weight Decreased Female 6/10/2009 Consumer United Kingdom
Primary
Concomitant
Ventricular Extrasystoles Death 6/23/2009 Female 189 lb 6/24/2009 Other Health Professional United States
Primary
Concomitant
Hepatotoxicity Other Serious 53 Male 143 lb 8/13/2009 Pharmacist United States
Primary
Concomitant
Skin Tightness Other Serious 52 Male 168 lb 9/21/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Diverticulitis Hospitalization 4/18/2008 59 Male 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 52 Female 10/12/2009 United States
Primary
Concomitant
Weight Bearing Difficulty Hospitalization 7/1/2008 46 Male 12/2/2009 United States
Primary
Concomitant
Syncope Hospitalization 7/1/2008 46 Male 12/4/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 61 Male 12/24/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Serotonin Syndrome Other Serious 61 Male 12/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Tremor Other Serious 61 Male 12/28/2009 Other Health Professional United States
Primary
Concomitant
Interacting
Skin Tightness Other Serious 1/1/2005 49 Male 168 lb 1/4/2010 Physician United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Death 11/10/2008 23 Male 1/11/2010 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious 7/20/2005 Male 1/12/2010 United States
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 61 Male 1/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2005 49 Male 168 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Phantom Pain Other Serious 21 Male 101 lb 1/27/2010
Primary
Secondary
Concomitant
Skin Tightness Other Serious 1/1/2005 49 Male 168 lb 4/21/2010 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Required Intervention 61 Male 5/28/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2004 6/17/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 3/14/2006 50 Female 6/18/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2005 61 Male 245 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 7/23/2010 United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 5/30/2010 62 Female 129 lb 7/26/2010 Physician United States
Primary
Secondary
Concomitant
Toothache Other Serious 10/4/2004 57 Male 212 lb 7/30/2010 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 5/30/2010 62 Female 129 lb 8/3/2010 Physician United States
Primary
Secondary
Concomitant
Neurotoxicity Other Serious 63 Male 8/5/2010 Physician United States
Primary
Secondary
Wound Dehiscence Other Serious 1/1/2000 34 Male 8/5/2010 United States
Primary
Secondary
Concomitant
Blood Creatine Increased 4/11/2009 32 Male 165 lb 8/6/2010 Pharmacist United States
Primary
Concomitant
Toothache Other Serious 10/4/2004 57 Male 212 lb 8/16/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/20/2005 66 Male 8/20/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Tension Headache Other Serious 8/13/2010 63 Female 132 lb 8/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 35 Male 8/27/2010 United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 8/30/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/20/2005 66 Male 8/28/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 42 Female 9/2/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 35 Male 9/2/2010 United States
Primary
Concomitant
Suicide Attempt Other Serious 5/1/2008 46 Female 9/8/2010 Lawyer United States
Primary
Concomitant
Musculoskeletal Pain Other Serious 4/1/2008 54 Male 9/21/2010 Lawyer United States
Primary
Concomitant
Thrombophlebitis Superficial Other Serious 3/1/2008 16 Female 130 lb 12/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 1/1/2009 35 Female 1/7/2011 Physician United States
Primary
Secondary
Tremor Hospitalization 3/14/2006 50 Female 1/7/2011 Physician United States
Primary
Concomitant
Completed Suicide Death 38 Female 1/12/2011 Physician United States
Primary
Secondary
Product Quality Issue 12/1/2010 36 Female 175 lb 1/14/2011 Consumer United States
Primary
Concomitant
Withdrawal Syndrome 12/1/2010 36 Female 175 lb 1/17/2011 Consumer United States
Primary
Concomitant
Completed Suicide Death 70 Female 1/19/2011 Physician United States
Primary
Secondary
Vertigo Other Serious 12/18/2006 67 Male 1/26/2011 Physician United States
Primary
Secondary
Concomitant
Metabolic Syndrome Hospitalization 6/1/2006 47 Female 1/26/2011 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 1/22/2011 56 Female 150 lb 1/31/2011 Consumer United States
Primary
Concomitant
Tongue Ulceration Hospitalization 1/3/2011 16 Male 118 lb 1/31/2011 Physician United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 35 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Toxicity To Various Agents Death 1/1/2009 35 Female 1/27/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 2/22/2011 Physician United States
Primary
Secondary
Death Death 1/1/2009 35 Female 2/7/2011 Physician United States
Primary
Secondary
Death Death 35 Female 2/23/2011 Physician United States
Primary
Secondary
Renal Failure Other Serious 9/28/2010 70 Male 190 lb 2/23/2011 Other Health Professional United States
Primary
Concomitant
Neoplasm Malignant Other Serious 10/4/2004 57 Male 212 lb 2/24/2011 Lawyer United States
Primary
Concomitant
Toxicity To Various Agents Death Female 2/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 3/1/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 46 Female 3/1/2011 Physician United States
Primary
Secondary
Cholecystitis Chronic Hospitalization 7/22/2008 -3 Female 260 lb 3/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Intentional Death 35 Female 3/3/2011 Other Health Professional United States
Primary
Secondary
Drug Prescribing Error Death 1/15/2009 55 Female 175 lb 3/4/2011 Consumer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 38 Female 3/24/2011 Physician United States
Primary
Secondary
Renal Failure Chronic Other Serious 1/1/2000 52 Female 140 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diarrhoea Other Serious 61 Female 5/6/2011 Consumer United States
Primary
Concomitant
Clostridium Difficile Colitis Hospitalization 5/10/2011 49 Male 176 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 5/10/2011 49 Male 176 lb 6/6/2011 Physician United States
Primary
Secondary
Concomitant
Headache Other Serious 4/1/2008 54 Male 6/17/2011 Lawyer United States
Primary
Concomitant
Rectal Ulcer Hospitalization 5/10/2011 49 Male 176 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Abnormal Behaviour Hospitalization 10/1/2009 35 Female 7/24/2012 Lawyer United States
Primary
Concomitant
Hyperreflexia Other Serious 68 Female 185 lb 8/8/2012 Physician United States
Primary
Secondary
Concomitant
Interacting
Toxicity To Various Agents Death 12/16/2007 55 Female 180 lb 10/10/2012 Physician Us
Primary
Secondary
Concomitant
Oesophagitis Other Serious Female 192 lb 10/31/2012 Lawyer Us
Primary
Concomitant
Accidental Death Death 22 Male 8/29/2012 Consumer Us
Primary
Secondary
Intestinal Perforation Death 10/15/2011 69 Male 2/27/2013 Physician Us
Primary
Secondary
Concomitant
Transaminases Increased Hospitalization 10/20/2011 71 Male 204 lb 1/17/2013 Consumer Us
Primary
Secondary
Concomitant
Fistula Hospitalization 8/9/2011 63 Male 196 lb 12/12/2012 Physician Us
Primary
Concomitant
Fatigue Hospitalization 4/1/2012 60 Male 172 lb 10/24/2012 Consumer Us
Primary
Concomitant
Pneumonia Aspiration Other Serious 10/2011 69 Female 185 lb 4/22/2013 Other Health Professional Us
Primary
Concomitant
Thrombosis Other Serious 49 Male 9/24/2012 Consumer Us
Primary
Concomitant
Bradycardia Other Serious 57 Male 161 lb 10/18/2013 Consumer Us
Primary
Secondary
Concomitant
Jugular Vein Thrombosis Hospitalization 3/6/2012 17 Female 123 lb 9/17/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 7/27/2012 40 Male 4/5/2013 Physician Us
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 8/25/2012 68 Male 9/19/2012 Other Health Professional Us
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/2012 Male 229 lb 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 68 Female 185 lb 9/7/2012 Physician Us
Primary
Secondary
Concomitant
Intentional Drug Misuse 52 Female 9/25/2012 Us
Primary
Secondary
Concomitant
Renal Failure Death 9/24/2012 75 Male 207 lb 10/15/2012 Physician Us
Primary
Concomitant
Respiratory Arrest Death 10/1/2012 70 Male 12/26/2012 Consumer Us
Primary
Concomitant
Toxicity To Various Agents Hospitalization 8/2012 Male 10/10/2012 Physician Us
Primary
Secondary
Concomitant
Death Death 26 10/30/2012 Other Health Professional Country Not Specified
Primary
Secondary
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Post Procedural Haemorrhage Hospitalization 9/11/2012 33 Female 234 lb 11/6/2012 Physician Us
Primary
Concomitant
Sudden Death Hospitalization Male 187 lb 11/27/2012 Physician Us
Primary
Secondary
Concomitant
Septic Shock Hospitalization Male 187 lb 7/3/2013 Physician Us
Primary
Secondary
Concomitant
Product Solubility Abnormal Other Serious 11/30/2012 61 Male 131 lb 12/11/2012 Pharmacist Us
Primary
Concomitant
Vomiting Other Serious 12/7/2012 59 Female 220 lb 1/17/2013 Consumer Us
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Death 70 Male 207 lb 1/28/2013 Physician Ca
Primary
Concomitant
Tardive Dyskinesia Other Serious 12/21/2012 Physician Us
Primary
Concomitant
Pain In Jaw Hospitalization 12/7/2012 60 Female 220 lb 12/27/2012 Other Health Professional Us
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 12/6/2012 28 Female 162 lb 1/2/2013 Physician Us
Primary
Concomitant
Off Label Use 38 Female 160 lb 1/8/2013 Consumer Us
Primary
Concomitant
Drug Tolerance Hospitalization NotSpecified 1/10/2013 Pharmacist Us
Primary
Secondary
Concomitant
Interacting
Toxicity To Various Agents Death 57 Female 1/9/2013 Physician Us
Primary
Secondary
Respiratory Disorder Death NotSpecified 1/9/2013 Physician Us
Primary
Secondary
Intentional Drug Misuse Other Serious NotSpecified 2/5/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death 57 Female 1/17/2013 Physician Us
Primary
Secondary
Completed Suicide Death 57 Female 1/18/2013 Physician Country Not Specified
Primary
Secondary
Drug Abuse Death 24 Male 1/18/2013 Physician Us
Primary
Secondary
Completed Suicide Death 57 Female 1/20/2013 Physician Us
Primary
Secondary
Drug Abuse Death 24 Male 1/24/2013 Physician Us
Primary
Secondary
Completed Suicide Death 57 Female 1/28/2013 Country Not Specified
Primary
Secondary
Drug Level Decreased Hospitalization 51 Male 2/5/2013 Other Health Professional Us
Primary
Concomitant
Interacting
Pneumonia Other Serious 10/21/2012 58 Female 198 lb 7/8/2013 Physician Us
Primary
Secondary
Concomitant
Death Death 57 Female 1/28/2013 Physician Us
Primary
Secondary
Suicide Attempt Life Threatening 1/18/2013 59 Female 121 lb 1/28/2013 Physician Us
Primary
Concomitant
Neutrophil Count Decreased Other Serious 1/17/2013 28 Female 158 lb 3/11/2013 Physician Us
Primary
Concomitant
Hypertrophic Cardiomyopathy Death 7/23/2012 51 Female 237 lb 1/22/2013 Physician Us
Primary
Secondary
Concomitant
Completed Suicide Death 2011 57 Female 2/14/2013 Physician Us
Primary
Secondary
Prothrombin Time Prolonged Hospitalization Female 165 lb 3/15/2013 Physician Us
Primary
Concomitant
Completed Suicide Death 57 Female 2/8/2013 Other Health Professional Us
Primary
Secondary
Vomiting Other Serious 12/7/2012 60 Female 220 lb 2/8/2013 Us
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 57 Female 2/26/2013 Physician Country Not Specified
Primary
Secondary
Poisoning Death 2011 24 Male 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 57 Female 2/4/2013 Physician Us
Primary
Secondary
Respiratory Arrest Death 2011 57 Female 1/31/2013 Physician Us
Primary
Secondary
Nerve Injury 2012 Female 3/8/2013 Consumer Us
Primary
Concomitant
Suicidal Ideation Hospitalization 2007 Male 3/26/2013 Lawyer Ca
Primary
Secondary
Concomitant
Drug Ineffective 2/20/2013 Male 3/22/2013 Pharmacist Us
Primary
Concomitant
Pyrexia Hospitalization 3/29/2013 60 Male 187 lb 4/1/2013 Physician Country Not Specified
Primary
Concomitant
Death Death 3/18/2013 59 Female 4/12/2013 Pharmacist Us
Primary
Concomitant
Renal Injury Life Threatening 4/2/2013 58 Female 109 lb 6/20/2013 Physician Us
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 4/23/2013 45 Female 6/7/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2013 56 Female 5/9/2013 Consumer Us
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/19/2013 56 Male 273 lb 6/24/2013 Physician Us
Primary
Secondary
Concomitant
Lower Limb Fracture Other Serious Male 7/1/2013 Other Health Professional Us
Primary
Secondary
Sensory Disturbance Other Serious 43 Female 7/2/2013 Other Health Professional Country Not Specified
Primary
Secondary
Asthenia Hospitalization 4/25/2011 50 Female 128 lb 7/8/2013 Physician Kr
Primary
Concomitant
Vascular Occlusion Death 9/2003 61 Female 142 lb 8/13/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/2006 48 Female 6/14/2013 Physician Us
Primary
Concomitant
Vision Blurred Hospitalization 2002 54 Female 226 lb 8/12/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 3/17/2004 56 Female 140 lb 8/13/2013 Physician Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2007 51 Female 8/8/2013 Consumer Us
Primary
Concomitant
Urinary Tract Infection Other Serious 2003 Female 10/10/2012 Consumer Us
Primary
Concomitant

Drug Data