Hydromorphone Hcl combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 11/1/2004 61 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 7/22/2004 9/12/2005 Physician United States
Primary
Concomitant
Pneumonitis Hospitalization 9/12/2005 75 Female 150 lb 2/2/2006 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 11/1/2005 79 Female 110 lb 2/8/2006 Physician Germany
Primary
Concomitant
Death Death 3/2/2006 Female 3/15/2006 Physician Canada
Primary
Concomitant
Ventricular Tachycardia Other Serious 31 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 3/28/2006 50 Female 4/28/2006 United States
Primary
Concomitant
International Normalised Ratio Decreased Life Threatening 1/31/2006 29 Female 2/14/2006 United States
Primary
Concomitant
Pseudomonas Infection Hospitalization 4/9/2006 55 Male 203 lb 5/12/2006 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 7/1/2005 40 Male 6/15/2006 Consumer Canada
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/24/2006 50 Female 6/13/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/21/2005 57 Female 251 lb 6/28/2006 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 6/29/2006 Physician Germany
Primary
Secondary
Concomitant
Haemolytic Anaemia Other Serious 71 Female 8/1/2006 Consumer Canada
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/15/2006 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/9/2006 55 Male 203 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 38 Female 8/25/2006 Canada
Primary
Secondary
Drug Toxicity Death 33 Male 8/25/2006 Canada
Primary
Secondary
Pneumonia Death 58 Female 8/25/2006 Canada
Primary
Secondary
Drug Toxicity Death 40 Male 8/25/2006 Canada
Primary
Secondary
Pulmonary Embolism Death 51 Male 8/25/2006 Canada
Primary
Secondary
Injection Site Inflammation Death 28 Female 8/25/2006 Canada
Primary
Secondary
Pulmonary Embolism Other Serious 51 Male 8/21/2006 Other Health Professional Canada
Primary
Secondary
Pulmonary Embolism Death 51 Male 9/7/2006 Canada
Primary
Concomitant
Injection Site Inflammation Death 28 Female 9/7/2006 Canada
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 8/20/2006 8 Female 68 lb 9/19/2006 Consumer United States
Primary
Secondary
Concomitant
Delirium Hospitalization 7/5/2006 62 Male 9/13/2006 Other Health Professional United States
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Stomach Discomfort Death 88 Female 176 lb 12/8/2006 Physician Canada
Primary
Concomitant
Serotonin Syndrome Other Serious 53 Male 12/20/2006 Consumer United States
Primary
Concomitant
Thrombosis Required Intervention 8/18/2006 70 Female 142 lb 9/5/2006 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 53 Male 3/2/2007 United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 12/1/2005 41 Female 3/2/2007 United States
Primary
Concomitant
Rash Generalised Other Serious 2/7/2007 35 Female 101 lb 2/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious Male 260 lb 3/16/2007 Consumer Canada
Primary
Concomitant
Pericardial Effusion Other Serious 11/30/2005 41 Female 190 lb 3/15/2007 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2007 Male 3/26/2007 Physician United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Required Intervention 11/3/2006 Female 93 lb 11/14/2006 Pharmacist United States
Primary
Concomitant
Sleep Walking Other Serious 1/4/2003 Female 4/13/2007 Consumer United States
Primary
Concomitant
Wound Secretion Other Serious Male 260 lb 4/13/2007 Consumer Canada
Primary
Concomitant
Tracheitis Hospitalization 1/31/2007 Male 145 lb 4/16/2007 United States
Primary
Secondary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 3/15/2007 Male 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Polymedication 7/23/2006 58 Female 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Viral Tracheitis Hospitalization 1/31/2007 74 Male 145 lb 4/23/2007 Physician United States
Primary
Secondary
Concomitant
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Skin Disorder Hospitalization 2/21/2007 49 Male 201 lb 4/25/2007 Pharmacist United States
Primary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 Female 214 lb 5/17/2007 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 4/23/2007 Male 260 lb 5/25/2007 Other Health Professional Canada
Primary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/23/2007 Male 260 lb 6/14/2007 Physician Canada
Primary
Concomitant
Hallucination Other Serious 56 Female 6/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Incontinence Hospitalization 1/1/2006 Female 214 lb 7/5/2007 Consumer United States
Primary
Concomitant
Pruritus Death 1 Female 7/9/2007
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/13/2007 Physician United States
Primary
Concomitant
Convulsion Hospitalization 6/29/2007 58 Female 7/13/2007 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 10/16/2006 Male 7/23/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 7/25/2007 Physician United States
Primary
Concomitant
Thrombophlebitis Superficial Life Threatening 10/16/2006 Male 7/31/2007 Physician United States
Primary
Concomitant
Hepatic Steatosis Other Serious 4/1/2007 41 Female 8/2/2007 Physician United States
Primary
Concomitant
Stress Other Serious 10/9/2000 Female 132 lb 8/3/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 8/7/2007 Physician United States
Primary
Concomitant
Neck Pain Hospitalization 6/29/2007 58 Female 8/10/2007 Canada
Primary
Concomitant
Respiratory Failure Hospitalization 10/16/2006 Male 8/20/2007 Physician United States
Primary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 8/28/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 45 Female 9/13/2007
Primary
Secondary
Concomitant
Convulsion Hospitalization 10/1/2007 59 Male 187 lb 10/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Death 1/1/2006 Male 90 lb 11/13/2007 Canada
Primary
Concomitant
Ventricular Tachycardia Life Threatening 8/6/2007 Female 142 lb 11/5/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 10/28/2007 14 Female 126 lb 11/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 3 Female 162 lb 11/10/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 Female 162 lb 11/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 126 lb 11/21/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 47 Female 11/28/2007
Primary
Secondary
Concomitant
Intestinal Obstruction Death 1/1/2006 Male 90 lb 12/4/2007 Canada
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2007 61 Male 12/14/2007 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 12/14/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 12/5/2007 61 Male 12/27/2007 Physician United States
Primary
Concomitant
Dystonia Hospitalization 5/26/2007 19 Female 105 lb 12/28/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 12/4/2007 72 Female 191 lb 12/24/2007 United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 10/30/2007 31 Female 162 lb 1/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 31 Female 162 lb 1/26/2008 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 6/29/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 2/25/2008 52 Female 220 lb 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Required Intervention 1/16/2008 53 Female 141 lb 3/19/2008 Pharmacist United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 10/30/2007 Female 162 lb 4/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 12/20/2007 Female 4/25/2008 Consumer Canada
Primary
Concomitant
Leukopenia Other Serious 5/12/2006 62 Female 185 lb 4/29/2008 Physician Germany
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 33 Female 5/16/2008
Primary
Secondary
Concomitant
Hyperaesthesia Other Serious 45 Female 6/6/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 58 Male 6/9/2008 Physician Canada
Primary
Secondary
Electrocardiogram Qt Prolonged Disability 7/23/2008 Male 151 lb 7/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 9/30/2005 Female 8/18/2008 Consumer Canada
Primary
Secondary
Concomitant
Treatment Failure Other Serious 24 Female 9/11/2008 Physician United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 7/24/2008 Female 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 56 Male 9/22/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/28/2008 42 Female 167 lb 10/1/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hyperaesthesia Hospitalization 10/3/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Required Intervention 9/29/2008 51 Female 130 lb 10/3/2008 Pharmacist United States
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 10/12/2008 32 Female 253 lb 10/17/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/28/2008 Physician United States
Primary
Secondary
Concomitant
Sedation Life Threatening 6/2/2008 Male 150 lb 6/9/2008 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 8/21/2008 44 Female 150 lb 10/1/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Death Death Female 260 lb 12/16/2008 Consumer United States
Primary
Concomitant
Drug Toxicity Other Serious 58 Male 1/6/2009 Physician Canada
Primary
Secondary
Thrombocytopenia Hospitalization 11/28/2008 Female 119 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Tooth Extraction Other Serious Female 1/14/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/9/2008 Male 1/19/2009 Lawyer United States
Primary
Concomitant
Urticaria Hospitalization 15 Male 101 lb 1/23/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization Female 260 lb 1/29/2009 Physician United States
Primary
Concomitant
Drug Toxicity Death 49 Female 2/6/2009 Physician United States
Primary
Concomitant
Palpitations Hospitalization 11/1/2008 40 Female 2/6/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/9/2008 82 Male 2/19/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 11/1/2007 71 Female 2/20/2009 Lawyer United States
Primary
Concomitant
Tooth Extraction Other Serious Female 3/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/5/2009 52 Male 206 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 56 Male 3/31/2009
Primary
Secondary
Pulmonary Embolism Other Serious 1/1/2003 36 Female 4/6/2009 United States
Primary
Concomitant
Lethargy Hospitalization 2/1/2009 51 Male 4/7/2009 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/17/2009 60 Female 181 lb 4/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Toxicity Death 49 Female 4/9/2009 Consumer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 2/1/2003 Female 4/11/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2005 57 Male 155 lb 4/14/2009 United States
Primary
Concomitant
Hypertensive Crisis Life Threatening 1/19/2009 Male 4/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Blood Creatinine Abnormal Hospitalization 11/1/2008 Female 110 lb 11/4/2008 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Required Intervention 2/15/2009 59 Female 123 lb 2/17/2009 Pharmacist United States
Primary
Secondary
Concomitant
Serotonin Syndrome 3/1/2009 55 Female 156 lb 3/30/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 3/7/2009 81 Male 161 lb 3/10/2009 Pharmacist United States
Primary
Concomitant
Lethargy Required Intervention 2/24/2009 46 Male 192 lb 4/6/2009 Pharmacist United States
Primary
Concomitant
Respiratory Rate Decreased Required Intervention 3/7/2009 32 Male 159 lb 3/23/2009 Pharmacist United States
Primary
Concomitant
Application Site Discolouration 5/6/2009 1 Female 13 lb 5/6/2009 Pharmacist United States
Primary
Concomitant
Ovarian Cancer Other Serious 10/13/2008 Female 107 lb 5/15/2009 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Other Serious 6/29/2005 40 Male 5/27/2009 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2004 Male 210 lb 5/28/2009 Consumer United States
Primary
Secondary
Concomitant
Mydriasis Required Intervention 5/18/2009 58 Male 6/1/2009 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Life Threatening 8/20/2008 71 Female 6/10/2009 Physician Germany
Primary
Secondary
Concomitant
Hallucination Life Threatening 3/7/2009 30 Male 174 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 11/1/2007 82 Male 7/16/2009 Physician United States
Primary
Concomitant
Restlessness Other Serious 50 Female 110 lb 7/17/2009 United States
Primary
Concomitant
Urticaria Female 7/23/2009 Consumer
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 143 lb 7/27/2009 United States
Primary
Concomitant
Pulmonary Hypertension Life Threatening 2/1/2009 Female 7/28/2009 Physician Canada
Primary
Concomitant

Drug Data