Hydrochlorothiazide combined with Warfarin

Reports:


Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Life Threatening Female 122 lb 1/17/2006 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 9/10/2005 Female 9/12/2005 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/2/2005 71 Male 1/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Haematemesis Hospitalization 10/31/2005 75 Female 11/28/2005 Pharmacist United States
Primary
Secondary
Concomitant
Localised Infection Hospitalization 12/31/2005 71 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 Male 234 lb 2/14/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/5/2006 59 Female 2/6/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Required Intervention 9/19/2005 69 Male 228 lb 2/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 11/1/2005 76 Male 175 lb 2/14/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 1/1/2000 53 Female 198 lb 2/23/2006 Physician United States
Primary
Concomitant
Paradoxical Drug Reaction 10/11/2005 81 Female 150 lb 1/5/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 Male 234 lb 2/27/2006 Lawyer United States
Primary
Concomitant
Dilatation Atrial Hospitalization 9/1/2005 58 Female 160 lb 3/10/2006 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Life Threatening 4/2/2006 72 Female 157 lb 4/5/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 1/1/2000 78 Female 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Nausea Disability 10/10/2005 40 Male 240 lb 4/6/2006 Pharmacist United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/18/1999 69 Male 234 lb 4/11/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 4/11/2003 69 Female 154 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 3/22/2000 78 Male 205 lb 4/26/2006 Physician United States
Primary
Concomitant
Neoplasm Malignant Hospitalization 4/11/2003 69 Female 154 lb 5/1/2006 Physician United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/1/2000 40 Female 181 lb 5/2/2006 Lawyer United States
Primary
Concomitant
Respiratory Distress Hospitalization 1/1/2000 78 Female 150 lb 5/3/2006 Physician United States
Primary
Concomitant
Sleep Apnoea Syndrome Hospitalization 11/18/1999 69 Male 234 lb 5/18/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/24/2006 82 Female 128 lb 3/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cells Urine Positive Hospitalization 3/9/2007 Male 161 lb 4/26/2007 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Male 271 lb 4/26/2007 Consumer United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 3/1/2007 78 Female 5/3/2007 Consumer United States
Primary
Secondary
Concomitant
Neutrophil Count Decreased Other Serious 5/2/2007 Male 5/2/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 5/14/2007
Primary
Secondary
Concomitant
Dyspnoea 72 Female 132 lb 6/22/2007 Consumer United States
Primary
Concomitant
Dysgeusia 2/4/2007 78 Male 210 lb 7/10/2007 Consumer United States
Primary
Concomitant
Mammogram Abnormal Other Serious 1/1/2006 60 Female 184 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Application Site Pruritus 1/26/2007 82 Female 8/27/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 7/24/2007 81 Male 196 lb 9/3/2007 Physician United States
Primary
Secondary
Concomitant
Erythema 1/22/2007 81 Male 181 lb 9/20/2007 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/1996 52 Female 143 lb 12/13/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 49 Female 8/29/2008 Pharmacist United States
Primary
Concomitant
Renal Impairment Other Serious 74 Male 10/30/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Blood Pressure Increased Male 1/12/2009 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 12/24/2008 Female 170 lb 2/5/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/6/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/26/2008 60 Female 135 lb 2/12/2009 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 2/20/2009 Physician United States
Primary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2008 Female 200 lb 3/26/2009 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 4/2/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/21/2008 Male 4/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Fall Required Intervention 11/28/2008 73 Female 135 lb 12/2/2008 Pharmacist United States
Primary
Concomitant
Myositis Hospitalization 2/1/2009 66 Male 4/29/2009 Pharmacist Canada
Primary
Secondary
Concomitant
Swelling Face 1/1/2007 5/4/2009 United States
Primary
Concomitant
Tongue Haemorrhage Other Serious 1/8/2009 64 5/11/2009 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonia Hospitalization Female 6/3/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Life Threatening 1/13/2009 40 Female 192 lb 6/25/2009 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Life Threatening 1/13/2009 40 Female 192 lb 7/9/2009 Other Health Professional United States
Primary
Concomitant
Acute Left Ventricular Failure Life Threatening 4/2/2009 84 Female 7/28/2009 United Kingdom
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/7/2009 Female 8/11/2009 Pharmacist United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 8/11/2009 United States
Primary
Concomitant
Flushing 8/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Pruritus Male 8/22/2009 United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 1/1/2006 Female 200 lb 8/25/2009 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal 5/12/2009 Male 220 lb 8/29/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 61 Female 9/2/2009 Lawyer United States
Primary
Concomitant
Injury Death 64 Female 9/10/2009 Lawyer United States
Primary
Concomitant
Vomiting 8/18/2009 56 Male 9/18/2009 Other Health Professional United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 69 Female 9/14/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 60 Male 215 lb 9/16/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 6/5/2009 67 Female 93 lb 6/8/2009 Pharmacist United States
Primary
Concomitant
Sciatica Other Serious 9/1/2009 Female 10/9/2009 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2009 Female 173 lb 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/1/2009 65 Male 190 lb 11/20/2009 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2009 Female 173 lb 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/8/2006 64 Female 12/10/2009 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 70 Female 12/11/2009 United States
Primary
Concomitant
Thyroid Disorder Other Serious 4/21/2008 66 Female 137 lb 12/9/2009 United States
Primary
Concomitant
Pickwickian Syndrome Life Threatening 11/18/2009 Female 12/24/2009 Physician United States
Primary
Concomitant
Occult Blood Positive Other Serious 12/22/2009 73 Female 1/4/2010 Consumer United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 1/1/2009 Male 190 lb 1/4/2010 Physician United States
Primary
Secondary
Concomitant
No Adverse Event 65 Male 190 lb 1/19/2010 Physician United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 65 Male 1/29/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 64 Female 1/21/2010 Lawyer United States
Primary
Concomitant
Lymphangitis Hospitalization 2/4/2010 69 Female 137 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 65 Male 2/9/2010 Consumer United States
Primary
Concomitant
Pulmonary Oedema Other Serious 1/1/2009 57 Male 127 lb 4/1/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Oedema Other Serious 12/8/2009 68 Female 217 lb 5/6/2010 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 11/6/2009 66 Male 5/12/2010 Pharmacist Canada
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 4/28/2010 68 Male 214 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 2/1/2004 79 Female 150 lb 5/14/2010 Consumer United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 11/6/2009 66 Male 6/2/2010 Pharmacist Canada
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 2/1/2004 79 Female 150 lb 6/8/2010 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2008 45 Female 6/11/2010 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2007 52 Male 174 lb 6/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/3/2010 86 Male 190 lb 6/18/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Incontinence 4/1/2010 83 Female 6/25/2010 Consumer
Primary
Concomitant
Electrocardiogram Qt Prolonged 8/7/2007 78 Female 6/29/2010 Other Health Professional United States
Primary
Concomitant
Dysphonia 6/7/2010 81 Male 207 lb 6/28/2010 Consumer
Primary
Secondary
Concomitant
Rash Pruritic 3/1/2006 85 Female 160 lb 6/28/2010 Consumer United States
Primary
Concomitant
Madarosis 8/1/2007 76 Female 204 lb 6/28/2010 Consumer United States
Primary
Concomitant
Drug Interaction 71 Male 207 lb 6/29/2010 Consumer United States
Primary
Concomitant
Interacting
Ovarian Cancer Hospitalization 6/21/2010 54 Female 157 lb 7/5/2010 Other Health Professional United States
Primary
Concomitant
Suicidal Ideation Life Threatening 1/5/2009 40 Female 192 lb 7/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 2/4/2010 80 Male 187 lb 7/7/2010 Consumer United States
Primary
Secondary
Concomitant
Irritable Bowel Syndrome 10/1/2008 54 150 lb 7/7/2010 Consumer United States
Primary
Concomitant
Dizziness Other Serious Male 7/14/2010 United States
Primary
Concomitant
Suicide Attempt Other Serious 3/25/2008 46 Male 7/23/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2000 51 Male 210 lb 7/26/2010 Lawyer United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/22/2007 80 Male 185 lb 7/27/2010 United States
Primary
Secondary
Concomitant
Dizziness Other Serious 6/28/2010 Male 7/29/2010 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 11/9/2008 84 Female 103 lb 7/29/2010 Physician United States
Primary
Concomitant
Interacting
Rash Pruritic 3/1/1999 57 Male 245 lb 7/31/2010 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 7/1/2008 75 Female 200 lb 7/31/2010 Consumer United States
Primary
Secondary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/19/2010 65 Female 254 lb 8/5/2010 Physician United States
Primary
Concomitant
Flushing 5/20/2010 59 Male 225 lb 8/16/2010 Consumer United States
Primary
Concomitant
Stomatitis 72 Male 8/17/2010 Consumer United States
Primary
Concomitant
Renal Cell Carcinoma Other Serious 9/15/2008 71 Male 8/17/2010 Consumer Canada
Primary
Secondary
Concomitant
Hypotension Other Serious Female 8/24/2010 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 72 Male 8/24/2010 Consumer United States
Primary
Concomitant
Feeling Abnormal 6/1/2010 67 Female 8/24/2010 Consumer
Primary
Concomitant
Rash Other Serious 7/1/2010 76 Male 215 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 8/19/2010 69 Female 123 lb 9/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1/1/1999 59 Female 187 lb 9/8/2010 Physician United States
Primary
Secondary
Concomitant
Somnolence 4/3/2009 60 Female 180 lb 9/9/2010 Other Health Professional United States
Primary
Concomitant
Clostridial Infection Hospitalization 5/24/2010 59 Male 206 lb 9/14/2010 Physician United States
Primary
Concomitant
Off Label Use Other Serious 5/25/2010 73 Female 130 lb 9/20/2010 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 64 Male 169 lb 10/8/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 9/1/2010 74 Female 110 lb 10/10/2010 Consumer Brazil
Primary
Concomitant
Eye Irritation 9/1/2010 78 Male 250 lb 10/11/2010 Pharmacist United States
Primary
Concomitant
Pain In Extremity 1/1/2009 85 Male 165 lb 10/26/2010 Consumer United States
Primary
Concomitant
Vitreous Floaters Other Serious 1/1/1999 59 Female 187 lb 10/29/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/16/2008 82 Female 174 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased 9/1/2010 78 Male 249 lb 11/4/2010 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 9/1/2007 73 Male 214 lb 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vitreous Floaters Other Serious 1/1/1999 59 Female 187 lb 11/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 82 Male 140 lb 11/8/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 79 Male 11/2/2010 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 11/3/2010 83 Male 11/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 5/31/2010 67 Female 190 lb 11/22/2010 Consumer United States
Primary
Concomitant
Vitreous Floaters Other Serious 1/1/1999 59 Female 187 lb 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 7/29/2010 81 Male 185 lb 10/12/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2010 74 Female 110 lb 12/3/2010 Consumer Brazil
Primary
Concomitant
Tremor Other Serious 11/10/2009 73 Female 12/6/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vitreous Floaters Other Serious 1/1/1999 59 Female 187 lb 12/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant