Hydrochlorothiazide combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wheezing Hospitalization 9/8/2005 54 Female 2/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
Skin Burning Sensation Other Serious 5/1/1997 Female 107 lb 2/3/2006 United States
Primary
Secondary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/8/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/10/2006 United States
Primary
Concomitant
Troponin Increased Other Serious 12/27/2005 63 Male 159 lb 2/20/2006 Physician United States
Primary
Concomitant
Vomiting 49 Female 2/27/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/3/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/8/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 3/15/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/27/2003 44 Female 205 lb 4/6/2006 Lawyer United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2005 Female 4/4/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 4/10/2006 Physician United States
Primary
Concomitant
Uterine Disorder Hospitalization 8/1/2000 41 Female 185 lb 4/26/2006 Lawyer United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 5/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 5/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Infection Other Serious 1/1/2005 Female 5/8/2006 United States
Primary
Secondary
Concomitant
Pain In Extremity 11/16/2005 70 Male 3/23/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/13/2006 67 Female 162 lb 6/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 1/1/2004 Female 130 lb 6/1/2006 Consumer United States
Primary
Interacting
Hypokalaemia Hospitalization 5/17/2006 57 Female 5/26/2006 United States
Primary
Concomitant
Rash Disability 2/13/2006 61 Female 4/24/2006 United States
Primary
Concomitant
Stomatitis Hospitalization 5/17/2006 57 Female 6/12/2006 Physician United States
Primary
Concomitant
Stomatitis Hospitalization 5/17/2006 57 Female 6/16/2006 Physician United States
Primary
Concomitant
Tooth Abscess Other Serious 1/1/2005 Female 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Sleep Disorder Other Serious Female 157 lb 7/6/2006 Lawyer United States
Primary
Concomitant
Sleep Disorder Other Serious Female 157 lb 7/10/2006 Lawyer United States
Primary
Concomitant
Rash Other Serious 4/1/2006 56 Female 253 lb 7/11/2006 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious Female 157 lb 7/18/2006 Lawyer United States
Primary
Concomitant
Migraine Hospitalization 5/20/2006 38 Female 7/28/2006 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious Female 157 lb 8/7/2006 Lawyer United States
Primary
Secondary
Concomitant
Rash 5/1/2006 33 Female 165 lb 7/12/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 8/4/2006 Physician United States
Primary
Concomitant
Urticaria Disability 2/13/2006 61 Female 7/12/2006 United States
Primary
Concomitant
Nasopharyngitis Hospitalization 6/1/2006 61 Female 8/18/2006 Consumer United States
Primary
Concomitant
Migraine Hospitalization 5/20/2006 38 Female 8/22/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 12/27/2005 63 Male 159 lb 9/12/2006 Physician United States
Primary
Concomitant
Weight Decreased 3/9/2006 55 Male 256 lb 7/19/2006 Consumer United States
Primary
Concomitant
Stomatitis Hospitalization 5/17/2006 58 Female 10/24/2006 Physician United States
Primary
Concomitant
Dysphonia 1/1/2006 62 Male 10/30/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2005 84 Female 160 lb 8/18/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 170 lb 11/21/2006 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 5/5/2005 74 Female 11/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Temporal Arteritis Other Serious 11/6/2001 60 Female 8/18/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 11/3/1999 44 150 lb 8/18/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 170 lb 12/14/2006 Other Health Professional United States
Primary
Concomitant
Hypotension Other Serious 8/1/2006 58 Male 200 lb 12/21/2006 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 7/1/2005 67 Female 102 lb 11/28/2006 Physician United States
Primary
Concomitant
Somnolence 9/1/2006 57 Female 11/7/2006 Consumer United States
Primary
Concomitant
Urticaria Disability 2/13/2006 61 Female 10/23/2006 United States
Primary
Concomitant
Migraine Hospitalization 5/20/2006 38 Female 1/30/2007 Consumer United States
Primary
Concomitant
Pruritus Generalised Other Serious 1/17/2007 56 Female 230 lb 1/30/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2003 47 Female 290 lb 2/22/2007 Consumer United States
Primary
Concomitant
Hypoaesthesia Other Serious 3/1/2007 Female 3/21/2007 Consumer Canada
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 Male 195 lb 3/26/2007 Consumer United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Disability 1/1/2003 46 Female 8/17/2006 Lawyer United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2006 47 Female 3/28/2007 Consumer United States
Primary
Concomitant
Insomnia 10/20/2006 47 Female 200 lb 1/12/2007 Consumer United States
Primary
Concomitant
Insomnia 6/1/2006 52 Female 1/12/2007 Pharmacist United States
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 4/6/2007 57 Male 400 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Colitis Ischaemic Hospitalization 12/1/2005 65 Female 4/18/2007 United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2006 Female 165 lb 5/1/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious Female 267 lb 5/2/2007 Lawyer United States
Primary
Concomitant
Nasopharyngitis Other Serious 53 Female 5/5/2007 United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/1/2007 42 Female 190 lb 5/7/2007 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 26 Male 337 lb 5/15/2007 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 9/29/2006 Female 205 lb 6/4/2007 Physician United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/1/2007 42 Female 190 lb 6/25/2007 Physician United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 4/2/2003 30 Female 6/22/2007 Physician United States
Primary
Concomitant
Rectal Cancer Other Serious 4/1/2007 44 Female 7/6/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Discomfort Other Serious 6/25/2007 Female 146 lb 7/23/2007 Consumer United States
Primary
Concomitant
Surgery Other Serious 3/1/2007 Female 159 lb 7/27/2007 Consumer United States
Primary
Secondary
Concomitant
Trismus 1/1/2004 41 Female 8/1/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 4/25/2007 Female 150 lb 8/1/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 50 Female 8/21/2007 Consumer United States
Primary
Concomitant
Photopsia Other Serious 7/27/2007 Female 182 lb 8/31/2007 Consumer United States
Primary
Concomitant
Cystitis Hospitalization 68 Female 9/5/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious 7/5/2007 68 Female 9/13/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 68 Male 9/26/2007 Physician Germany
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2006 47 Female 10/4/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2007 Female 317 lb 10/19/2007 Physician United States
Primary
Concomitant
Photopsia Other Serious 7/27/2007 Female 182 lb 10/24/2007 Consumer United States
Primary
Concomitant
Musculoskeletal Discomfort Other Serious 6/25/2007 Female 146 lb 10/24/2007 Physician United States
Primary
Secondary
Concomitant
Nausea 3/1/2006 58 Male 10/25/2007 Consumer United States
Primary
Concomitant
Hypertension Other Serious 7/5/2007 68 Female 10/26/2007 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/23/2007 48 Female 10/31/2007 United States
Primary
Concomitant
Drug Ineffective 9/17/2007 50 Male 11/12/2007 Consumer United States
Primary
Concomitant
Knee Operation Hospitalization 3/28/2007 38 Female 264 lb 11/15/2007 Physician United States
Primary
Concomitant
Joint Swelling 6/15/2007 59 Female 11/16/2007 United States
Primary
Concomitant
Drug Ineffective 9/17/2007 50 Male 12/27/2007 Consumer United States
Primary
Concomitant
Myopathy Steroid Other Serious 12/6/2007 Female 12/28/2007 Pharmacist United States
Primary
Concomitant
Stomatitis Other Serious 11/1/2007 Male 235 lb 1/4/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 301 lb 1/16/2008 Consumer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 5/23/2007 48 Female 11/2/2007 United States
Primary
Concomitant
Sepsis Life Threatening 72 Female 119 lb 1/25/2008 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Other Serious 12/1/2007 61 Female 1/25/2008 Other Health Professional United States
Primary
Concomitant
Respiratory Disorder Other Serious 12/1/2007 61 Female 2/20/2008 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 68 Male 2/28/2008 Physician Germany
Primary
Concomitant
Soft Tissue Disorder Required Intervention 8/2/2006 60 Female 1/17/2008 Physician United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Female 181 lb 2/29/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 1/10/2008 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 6/1/2006 53 Female 239 lb 1/4/2008 Physician United States
Primary
Concomitant
Coronary Artery Disease Other Serious 2/4/2008 Male 300 lb 4/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tracheobronchitis Other Serious 12/1/2007 61 Female 4/17/2008 Other Health Professional United States
Primary
Concomitant
Drug Ineffective Hospitalization 51 Female 5/1/2008 Consumer United States
Primary
Concomitant
Somnolence Other Serious 1/1/2007 Female 181 lb 5/2/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious Female 260 lb 5/15/2008 United States
Primary
Concomitant
Throat Irritation Other Serious 5/16/2008 43 Male 240 lb 5/27/2008 Other Health Professional United States
Primary
Concomitant
Tracheobronchitis Other Serious 12/1/2007 61 Female 5/29/2008 United States
Primary
Concomitant
Pain Hospitalization 1/1/2008 Male 6/9/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 11/1/2006 61 Female 173 lb 4/10/2008 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2007 51 Female 419 lb 4/10/2008 Consumer United States
Primary
Concomitant
Palpitations Other Serious 2/1/2008 Female 140 lb 3/5/2008 United States
Primary
Concomitant
Suicidal Ideation Other Serious Female 260 lb 7/2/2008 United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Female 280 lb 7/22/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/18/2007 60 Female 150 lb 8/6/2008 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 37 Female 9/5/2008 Physician United States
Primary
Concomitant
Oral Pain Other Serious 48 Male 9/22/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 1/1/2008 39 Female 220 lb 9/25/2008 Consumer United States
Primary
Concomitant
Stress 5/16/2008 42 Female 200 lb 10/15/2008 Consumer United States
Primary
Concomitant
Urinary Incontinence Other Serious 1/1/2006 57 Male 240 lb 11/20/2008 United States
Primary
Concomitant
Gastric Haemorrhage Hospitalization 12/1/2007 46 Female 260 lb 9/29/2008 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/1/2008 36 Female 243 lb 12/1/2008 United States
Primary
Secondary
Concomitant
Spinal Fusion Surgery Other Serious 2/1/2008 Female 182 lb 12/16/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased 58 Female 199 lb 12/18/2008 Consumer United States
Primary
Concomitant
Spinal Fusion Surgery Other Serious 2/1/2008 Female 182 lb 1/26/2009 Consumer United States
Primary
Secondary
Concomitant
Flushing Female 2/24/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2006 Female 225 lb 2/27/2009 Consumer United States
Primary
Concomitant
Pruritus 1/28/2009 Female 180 lb 3/14/2009 Physician United States
Primary
Concomitant
Fatigue 5/2/2008 Female 207 lb 3/18/2009 Physician United States
Primary
Concomitant
Sleep Disorder Other Serious 1/1/1998 55 Male 3/19/2009 Consumer United States
Primary
Secondary
Concomitant
Vaginal Odour Hospitalization 1/1/2004 44 Female 170 lb 4/14/2009 United States
Primary
Concomitant
Rash Erythematous Hospitalization 3/20/2009 33 Female 227 lb 4/27/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 3/18/2002 38 Male 265 lb 5/19/2009 United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 9/29/2003 44 Female 221 lb 5/19/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/24/2000 40 Female 185 lb 5/21/2009 United States
Primary
Concomitant
Flushing Female 5/27/2009 United States
Primary
Concomitant
Flushing 4/13/2009 Male 5/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/1/2004 42 Female 6/2/2009 United States
Primary
Concomitant
Urticaria Hospitalization 2/24/2009 51 6/4/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 46 Female 225 lb 6/12/2009 United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse 5/1/2008 35 Female 207 lb 5/11/2009 United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2003 53 Female 6/25/2009 United States
Primary
Secondary
Concomitant
Therapeutic Response Prolonged Other Serious 1/1/1994 55 Male 6/25/2009 Consumer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 2/17/2006 47 Female 185 lb 6/30/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2000 33 Male 215 lb 7/7/2009 United States
Primary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Diabetic Retinopathy Other Serious 6/23/2003 31 Male 248 lb 7/14/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 45 Female 204 lb 7/15/2009 United States
Primary
Concomitant

Drug Data