Hydrochlorothiazide combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Productive Cough Other Serious 1/1/2005 87 Male 1/17/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Overdose Other Serious 1/1/1999 50 Male 236 lb 3/17/2006 Lawyer United States
Primary
Concomitant
Urinary Bladder Haemorrhage Hospitalization 61 Male 3/20/2006 Consumer United States
Primary
Concomitant
Paraesthesia Other Serious 73 Male 210 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 1 Female 4/1/2006 Other Health Professional Canada
Primary
Secondary
Weight Decreased 8/11/2005 66 Female 244 lb 1/20/2006 Consumer United States
Primary
Concomitant
Iris Disorder Disability 3/16/2006 81 Male 4/12/2006 Physician United States
Primary
Concomitant
Cystitis Haemorrhagic Hospitalization 4/27/2005 61 Male 4/18/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 1 Female 4/10/2006 Canada
Primary
Secondary
Weight Decreased Hospitalization 3/28/2006 60 Male 212 lb 4/13/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2004 65 Female 176 lb 5/5/2006 Physician United States
Primary
Concomitant
Periarthritis Hospitalization 8/13/2001 64 Female 170 lb 5/9/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 12/1/2004 84 Female 5/15/2006 Physician Chile
Primary
Secondary
Concomitant
Weight Increased 1/27/1994 55 Female 173 lb 5/22/2006 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious Female 6/9/2006
Primary
Secondary
Vitreous Floaters Other Serious 3/14/2006 81 Male 6/13/2006 Physician United States
Primary
Concomitant
Nausea 1/1/2006 68 Male 4/24/2006 United States
Primary
Concomitant
Renal Failure Hospitalization 1/24/2006 52 Female 6/16/2006 Physician France
Primary
Secondary
Concomitant
Meningeal Disorder Other Serious 54 Female 6/27/2006 Physician United States
Primary
Concomitant
Vitreous Floaters Other Serious 3/14/2006 81 Male 7/6/2006 Physician United States
Primary
Concomitant
Blood Glucose Fluctuation Male 7/21/2006 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 3/11/2005 65 Male 7/24/2006 Physician Russian Federation
Primary
Concomitant
Oedema Peripheral Hospitalization 7/7/2006 59 Female 118 lb 7/21/2006 Physician Canada
Primary
Concomitant
Vomiting 1/1/2006 68 Male 7/12/2006 United States
Primary
Concomitant
Restless Legs Syndrome Other Serious 7/28/2006 82 Female 8/25/2006 Physician United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious Female 9/6/2006 Canada
Primary
Concomitant
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Ventricular Hypertrophy Other Serious 10/13/2000 6 Female 53 lb 9/14/2006 Physician Canada
Primary
Secondary
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Paraesthesia 71 Female 10/30/2006 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 71 Male 10/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 76 Female 11/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 76 Female 11/14/2006 Physician Canada
Primary
Secondary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Lupus-like Syndrome Other Serious 49 Male 1/5/2007 Consumer United States
Primary
Secondary
Renal Impairment Hospitalization 11/8/2006 75 Male 1/8/2007
Primary
Secondary
Concomitant
Pulmonary Hypertension 6/1/2005 34 Female 165 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Lung Neoplasm Hospitalization 1/4/2007 65 Male 1/29/2007 Physician Hungary
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 1/30/2007 Physician United States
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/13/2007 Physician United States
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/23/2007 Physician United States
Primary
Concomitant
Sepsis Death 83 Female 181 lb 3/12/2007 Consumer United States
Primary
Concomitant
Haematemesis Other Serious 5/2/2006 Male 3/27/2007 Germany
Primary
Concomitant
Exercise Tolerance Decreased Life Threatening 9/1/2006 58 Male 176 lb 3/23/2007 Physician Poland
Primary
Concomitant
Haematemesis Other Serious 5/2/2006 Male 157 lb 4/4/2007 Germany
Primary
Concomitant
Loss Of Consciousness Hospitalization 9/1/2006 76 Male 220 lb 1/5/2007 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 4/30/2007 Consumer United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/2/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Death 4/12/2007 0 Female 4/27/2007 Consumer Netherlands
Primary
Concomitant
Decreased Appetite 12/1/2006 60 Female 2/16/2007 United States
Primary
Concomitant
Sepsis Death 83 Female 181 lb 5/9/2007 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 44 Male 5/11/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Myalgia Other Serious 4/13/2007 68 Male 181 lb 5/8/2007 Physician Germany
Primary
Secondary
Concomitant
Fatigue 11/4/2006 Male 2/22/2007 United States
Primary
Concomitant
Myocardial Ischaemia Life Threatening 9/1/2006 58 Male 176 lb 5/24/2007 Physician Poland
Primary
Concomitant
Visual Disturbance 2/18/2007 59 Male 5/17/2007 United States
Primary
Concomitant
Weight Decreased 1/20/2007 46 Male 326 lb 4/10/2007 Consumer United States
Primary
Concomitant
Pain In Extremity Other Serious 81 Female 129 lb 7/5/2007 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/2/2007 Female 208 lb 7/13/2007 Physician United States
Primary
Secondary
Concomitant
Restlessness Other Serious 7/1/2007 50 Male 7/17/2007 Consumer Canada
Primary
Concomitant
Urticaria 39 Female 8/1/2007 Consumer United States
Primary
Concomitant
Orthostatic Hypotension Hospitalization 10/17/2006 82 Female 8/8/2007 United Kingdom
Primary
Secondary
Concomitant
Wheezing Hospitalization 57 Female 8/18/2007 Physician Italy
Primary
Concomitant
Tachycardia Hospitalization 78 Female 8/17/2007 Greece
Primary
Secondary
Pharyngolaryngeal Pain 8/7/2007 63 Male 8/29/2007 Consumer United States
Primary
Concomitant
Nausea 4/19/2007 56 Male 7/11/2007 Consumer United States
Primary
Concomitant
Dyspnoea 7/1/2007 81 Male 9/6/2007 Consumer United States
Primary
Concomitant
Nerve Injury Other Serious Female 9/14/2007 Consumer United States
Primary
Secondary
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Dizziness 12/11/2006 77 Female 114 lb 8/16/2007 Physician United States
Primary
Concomitant
Nerve Injury Other Serious Female 9/29/2007 Consumer United States
Primary
Secondary
Somnolence Other Serious 64 Female 10/2/2007 Physician Italy
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/5/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/19/2007 United States
Primary
Concomitant
Pain In Extremity Hospitalization 8/24/2007 70 Male 10/24/2007 Consumer United States
Primary
Concomitant
Dysphonia 66 Female 10/26/2007 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/2/2007 Female 208 lb 10/30/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 10/30/2007 United States
Primary
Concomitant
Hypersensitivity Required Intervention 7/13/2007 83 Female 163 lb 10/22/2007 Physician United States
Primary
Concomitant
Nocturnal Dyspnoea 8/22/2007 69 Male 11/14/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 11/23/2007 United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 7/2/2007 Female 208 lb 11/28/2007 Physician United States
Primary
Secondary
Concomitant
Haemoconcentration Other Serious 8/16/2007 60 Male 11/16/2007 Russian Federation
Primary
Secondary
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 11/29/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 11/30/2007 United States
Primary
Concomitant
Uterine Disorder Other Serious 1/1/2001 53 Female 189 lb 12/3/2007 United States
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 2/19/2007 55 Male 236 lb 12/4/2007 Physician Canada
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 12/10/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/3/2007 Male 176 lb 12/10/2007 United States
Primary
Concomitant
Syncope Other Serious 1/1/2004 Female 103 lb 12/13/2007 United States
Primary
Secondary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Tongue Neoplasm Benign Required Intervention 6 Female 12/11/2007 United States
Primary
Concomitant
Incoherent Other Serious 11/1/2007 Male 250 lb 12/31/2007 United States
Primary
Concomitant
Pyrexia Hospitalization 11/28/2007 26 Female 115 lb 12/22/2007 Germany
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2006 Female 301 lb 1/16/2008 Consumer United States
Primary
Concomitant
Radiotherapy Other Serious 1/1/2001 53 Female 150 lb 11/5/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2007 Female 130 lb 1/24/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 9/28/2006 82 Female 1/29/2008 Physician Italy
Primary
Concomitant
Weight Decreased Other Serious 11/1/2006 Female 130 lb 2/21/2008 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 4/1/2007 57 Male 2/27/2008 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2007 64 Female 128 lb 3/3/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 48 Male 201 lb 3/11/2008 Physician Germany
Primary
Secondary
Concomitant
Oedema Peripheral 1/1/2007 64 Female 128 lb 3/19/2008 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 4/7/2008 Physician Germany
Primary
Secondary
Concomitant
Muscle Spasms 3/18/2008 63 Female 4/17/2008 Physician United States
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization 40 Female 4/21/2008 Physician France
Primary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 5/7/2008 Physician Germany
Primary
Secondary
Concomitant
Infection Hospitalization 2/19/2007 Male 236 lb 5/14/2008 Physician Canada
Primary
Secondary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 5/13/2008 Germany
Primary
Secondary
Concomitant
Hepatic Encephalopathy Hospitalization 2/19/2007 Male 236 lb 5/23/2008 Physician Canada
Primary
Secondary
Concomitant
Oesophageal Adenocarcinoma Life Threatening 12/28/2007 Male 215 lb 5/21/2008 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Hospitalization 5/7/2008 Female 245 lb 5/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 79 Male 5/30/2008 Consumer United States
Primary
Concomitant
Paraesthesia Hospitalization 5/7/2008 Female 245 lb 6/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/13/2008 Female 6/12/2008 Physician Germany
Primary
Secondary
Weight Increased Hospitalization 11/1/2006 61 Female 173 lb 4/10/2008 Consumer United States
Primary
Concomitant
Fall 11/1/2007 Male 210 lb 6/13/2008 United States
Primary
Concomitant
Shock Other Serious 70 Male 7/2/2008 Physician China
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 2/26/2007 0 Female 6 lb 6/15/2008 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Respiratory Tract Infection Hospitalization 2/26/2007 0 Female 6 lb 6/25/2008 Other Health Professional Korea, Democratic People's Republic Of
Primary
Concomitant
Shock Other Serious 3/1/2008 70 Male 7/9/2008 Physician China
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 1/1/1998 Female 150 lb 7/15/2008 United States
Primary
Secondary
Concomitant
Shock Other Serious 3/1/2008 70 Male 7/22/2008 Physician China
Primary
Secondary
Concomitant
Migraine 1/1/1998 52 Female 150 lb 7/23/2008 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2008 Female 157 lb 8/5/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/14/2006 Male 201 lb 8/5/2008 Physician Germany
Primary
Secondary
Concomitant
Dizziness 4/1/2008 45 Female 7/7/2008 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/15/2008 8/12/2008 Consumer United States
Primary
Secondary
Concomitant
Non-small Cell Lung Cancer Death 9/28/2007 Male 141 lb 8/13/2008 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 8/18/2008 Germany
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 80 Female 8/19/2008 Canada
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2008 Female 157 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious Female 157 lb 8/22/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 2/26/2007 0 Female 8/13/2008 Korea, Democratic People's Republic Of
Primary
Concomitant
Social Avoidant Behaviour Other Serious 7/1/2008 61 235 lb 8/22/2008 United States
Primary
Concomitant
Flushing 7/1/2008 Male 8/27/2008 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 5/1/2007 Male 8/27/2008 Canada
Primary
Concomitant
Palpitations Hospitalization 3/17/2008 76 Female 9/5/2008 Germany
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/12/2008 Other Health Professional Canada
Primary
Concomitant
Fall 11/1/2007 Male 210 lb 9/12/2008 United States
Primary
Concomitant
Therapeutic Response Unexpected Hospitalization 5/1/2008 53 Female 9/18/2008 Consumer United States
Primary
Secondary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 1/19/2008 41 Female 218 lb 9/10/2008 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2007 Male 35 lb 9/24/2008 Other Health Professional Canada
Primary
Concomitant
Therapeutic Response Unexpected Hospitalization 5/1/2008 Female 9/26/2008
Primary
Secondary
Concomitant

Drug Data