Hydrochlorothiazide combined with Pregabalin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Extremity 11/16/2005 70 Male 3/23/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 12/1/2005 70 Male 225 lb 4/6/2006 Consumer United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/31/2006 55 Male 2/17/2007 Spain
Primary
Secondary
Concomitant
Death Death 5/6/2007 37 Male 309 lb 6/15/2007 Pharmacist Turkey
Primary
Concomitant
Stomatitis Hospitalization 6/14/2007 Female 138 lb 6/15/2007 United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 5/9/2006 67 Female 8/10/2007 United States
Primary
Secondary
Concomitant
Lipomatosis Hospitalization 12/1/2004 64 Female 8/8/2007 Physician Germany
Primary
Secondary
Concomitant
Syncope Other Serious 2/2/2007 70 Female 11/30/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 3/3/2008 United States
Primary
Concomitant
Interacting
Systemic Lupus Erythematosus Other Serious 12/1/2007 Female 302 lb 3/15/2008 Physician United States
Primary
Concomitant
Death Death 3/15/2008 61 Female 3/21/2008 Netherlands
Primary
Secondary
Concomitant
Renal Impairment Other Serious 50 Female 3/21/2008 Physician United States
Primary
Concomitant
Interacting
Death Death 3/15/2008 61 Female 3/25/2008 Netherlands
Primary
Secondary
Concomitant
White Blood Cell Count Increased Required Intervention 50 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 3/15/2008 61 Female 3/26/2008 Physician Netherlands
Primary
Secondary
Concomitant
Death Death 3/15/2008 61 Female 3/28/2008 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 4/23/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 50 Female 5/2/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Renal Injury Other Serious 50 Female 4/25/2008 United States
Primary
Secondary
Death Death 3/15/2008 61 Female 5/19/2008 Physician Netherlands
Primary
Secondary
Concomitant
Pain In Extremity 4/1/2008 Female 226 lb 6/13/2008 United States
Primary
Concomitant
Injection Site Anaesthesia 4/1/2008 Female 228 lb 6/13/2008 United States
Primary
Concomitant
Tooth Extraction Other Serious 2/1/2008 Female 160 lb 6/19/2008 Canada
Primary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 1/1/2008 Female 190 lb 7/24/2008 United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Hypotension Life Threatening 6/17/2008 Female 257 lb 8/7/2008 United States
Primary
Concomitant
Pruritus 8/1/2008 Female 8/29/2008 United States
Primary
Concomitant
Hypotension Life Threatening 6/17/2008 Female 257 lb 9/9/2008 United States
Primary
Concomitant
Drug Ineffective 8/1/2007 Female 240 lb 9/12/2008 United States
Primary
Concomitant
Drug Ineffective 4/1/2008 Female 200 lb 9/12/2008 Consumer United States
Primary
Concomitant
Ear Infection 6/26/2008 Male 239 lb 9/12/2008 United States
Primary
Concomitant
Rash Macular 6/22/2008 Female 181 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 6/1/2008 Female 164 lb 9/12/2008 Consumer United States
Primary
Secondary
Concomitant
Renal Injury Hospitalization 50 Female 9/12/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 10/31/2006 55 Male 10/30/2008 Spain
Primary
Concomitant
Interacting
Pruritus 8/13/2008 Female 180 lb 11/26/2008 United States
Primary
Concomitant
Weight Increased 5/1/2008 Male 180 lb 12/12/2008 Physician United States
Primary
Concomitant
Wound 9/1/2008 Female 200 lb 12/12/2008 United States
Primary
Concomitant
Injection Site Reaction 6/1/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Non-cardiac Chest Pain Other Serious 2/19/2008 Female 216 lb 12/16/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 50 Female 12/11/2008 Physician United States
Primary
Concomitant
Agitation Hospitalization 11/9/2008 Male 171 lb 12/18/2008 United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Swollen Tongue 1/28/2009 Female 2/12/2009 Consumer
Primary
Concomitant
Hypotension Life Threatening 6/17/2008 Female 257 lb 2/18/2009 Other Health Professional United States
Primary
Concomitant
Agitation Hospitalization 11/8/2008 Male 171 lb 2/19/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 8/16/2008 54 Male 3/12/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 54 Male 172 lb 3/12/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Somnolence Life Threatening 1/16/2009 52 Male 3/24/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 10/26/2008 58 Female 143 lb 5/2/2009 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 5/13/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 6/15/2009 Other Health Professional Germany
Primary
Concomitant
Gait Disturbance Other Serious Male 200 lb 7/10/2009 Consumer United States
Primary
Concomitant
Irritability 9/2/2008 Female 255 lb 8/21/2009 Consumer United States
Primary
Concomitant
Hyperhidrosis 10/15/2008 Female 8/22/2009 United States
Primary
Concomitant
Gait Disturbance Other Serious Male 200 lb 8/31/2009 Physician United States
Primary
Concomitant
Injection Site Extravasation 8/1/2007 Female 240 lb 9/12/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 66 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Gait Disturbance Other Serious Male 200 lb 10/22/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 66 Female 238 lb 12/1/2009 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 12/7/2009 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 10/3/2009 69 Male 2/18/2010 Pharmacist United States
Primary
Secondary
Concomitant
Uterine Cancer Hospitalization 29 Female 276 lb 2/24/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 3/5/2010 42 Female 3/16/2010 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Other Serious 11/27/2007 62 Female 3/25/2010 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/26/2007 75 Male 4/7/2010 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/16/2008 54 Male 172 lb 5/4/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Non-cardiac Chest Pain Other Serious 2/19/2008 57 Female 216 lb 5/24/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing Other Serious 29 Female 125 lb 6/14/2010 United States
Primary
Concomitant
Pneumothorax Hospitalization 7/19/2010 59 Male 7/26/2010 Germany
Primary
Concomitant
Syncope Other Serious 77 Female 8/2/2010 Consumer Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 77 Female 8/18/2010 Consumer Germany
Primary
Secondary
Concomitant
Syncope Hospitalization 77 Female 8/18/2010 Consumer Germany
Primary
Secondary
Concomitant
Pneumothorax Hospitalization 7/19/2010 59 Male 8/16/2010 Germany
Primary
Concomitant
Non-dipping Hospitalization 77 Female 9/30/2010 Germany
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/1/2007 66 Female 238 lb 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 11/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 11/26/2010 Pharmacist Germany
Primary
Concomitant
Interacting
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 12/3/2010 Pharmacist Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Dehydration Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
Dehydration Life Threatening 8/16/2008 54 Male 172 lb 12/7/2010 Other Health Professional Germany
Primary
Concomitant
Interacting
International Normalised Ratio Increased Life Threatening 8/16/2008 54 Male 172 lb 12/9/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Wound Infection Other Serious 29 Female 276 lb 11/17/2010 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 8/16/2008 54 Male 12/14/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
Sinusitis 1/1/2009 12/15/2010 Consumer United States
Primary
Concomitant
Abdominal Pain 12/22/2010 Consumer United States
Primary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
Transient Ischaemic Attack Other Serious 11/19/2010 56 Male 234 lb 12/28/2010 Physician Australia
Primary
Secondary
Concomitant
Vomiting Other Serious 29 Female 276 lb 12/15/2010 United States
Primary
Concomitant
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Leg Amputation Other Serious 29 Female 276 lb 1/5/2011 United States
Primary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Injection Site Nodule 8/21/2010 50 Female 1/29/2011 Consumer United States
Primary
Concomitant
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 2/7/2011 Consumer Germany
Primary
Secondary
Concomitant
Pathological Fracture Other Serious 11/1/2010 56 Male 175 lb 2/14/2011 Physician United States
Primary
Concomitant
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 2/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Orthostatic Hypotension Other Serious Female 3/29/2011 Other Health Professional United States
Primary
Secondary
Wound Infection Hospitalization 29 Female 276 lb 4/13/2011 United States
Primary
Concomitant
Neuropathy Peripheral Hospitalization 2/9/2011 77 Male 243 lb 5/10/2011 Physician United States
Primary
Concomitant
Nervousness Hospitalization 1/7/2011 84 Male 173 lb 5/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Life Threatening 4/14/2010 63 Female 190 lb 5/17/2011 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/7/2011 84 Male 173 lb 5/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 6/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 4/23/2011 56 Female 7/5/2011 Other Health Professional France
Primary
Secondary
Back Pain Hospitalization 3/6/2008 51 Male 8/8/2011 United States
Primary
Concomitant
Hyponatraemia Other Serious 81 Female 8/24/2011 Other Health Professional France
Primary
Secondary
Dehydration Hospitalization 8/16/2008 54 Male 172 lb 8/26/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hyponatraemia Other Serious 81 Female 8/31/2011 Other Health Professional France
Primary
Secondary
Nail Disorder Other Serious 1/1/2011 61 Female 141 lb 9/2/2011 Consumer United States
Primary
Concomitant
Hyponatraemia Death 81 Female 9/13/2011 Other Health Professional France
Primary
Secondary
Bradycardia Hospitalization 1/7/2011 84 Male 173 lb 9/7/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoaesthesia 9/29/2011 55 Male 162 lb 11/16/2011 Consumer United States
Primary
Concomitant
Sinusitis Hospitalization 10/9/1996 23 Female 276 lb 11/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 11/23/2011 12/5/2011 Physician Germany
Primary
Secondary
Concomitant
Dehydration Hospitalization 1/7/2011 84 Male 173 lb 12/9/2011 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/23/2001 12/22/2011 Physician Netherlands
Primary
Secondary
Concomitant
B-cell Lymphoma Hospitalization 11/21/2011 50 Female 132 lb 12/26/2011 Physician Germany
Primary
Concomitant
Pulseless Electrical Activity Death 10/26/2011 Female 1/20/2012 Physician Germany
Primary
Concomitant
Electrolyte Imbalance Hospitalization 8/16/2008 54 Male 1/24/2012 Pharmacist Germany
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 8/16/2008 54 Male 172 lb 1/25/2012 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Pulseless Electrical Activity Death 10/26/2011 Female 1/26/2012 Other Health Professional Germany
Primary
Concomitant
Non-dipping Hospitalization 77 Female 2/1/2012 Germany
Primary
Secondary
Concomitant
Hypotension Hospitalization 77 Female 2/1/2012 Physician France
Primary
Concomitant
Interacting
Prothrombin Time Prolonged Hospitalization 8/16/2008 54 Male 2/7/2012 Pharmacist Germany
Primary
Secondary
Concomitant
B-cell Lymphoma Hospitalization 11/21/2011 50 Female 132 lb 2/10/2012 Physician Germany
Primary
Concomitant
Heart Rate Irregular Other Serious 6/1/2011 39 Male 225 lb 2/13/2012 Consumer United States
Primary
Secondary
Concomitant
Dysarthria Hospitalization 77 Female 2/23/2012 Physician France
Primary
Concomitant
Interacting
B-cell Lymphoma Hospitalization 11/21/2011 50 Female 132 lb 3/7/2012 Physician Germany
Primary
Concomitant
Fatigue Other Serious 1/1/2011 38 Male 225 lb 3/9/2012 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 1/7/2011 84 Male 173 lb 3/27/2012 United States
Primary
Secondary
Concomitant
Leukopenia Hospitalization Female 187 lb 4/11/2012 Other Health Professional Germany
Primary
Concomitant
B-cell Lymphoma Other Serious 11/21/2011 50 Female 132 lb 5/15/2012 Physician Germany
Primary
Concomitant
Gastroenteritis Viral Hospitalization 2/23/2012 68 Female 154 lb 6/12/2012 Physician Canada
Primary
Concomitant
Hemiparesis Other Serious 10/24/2011 68 Female 156 lb 6/13/2012 Physician Canada
Primary
Concomitant
Hypokalaemia Other Serious 2/23/2012 68 Female 154 lb 6/22/2012 Physician Canada
Primary
Concomitant
Aphasia Other Serious 10/24/2011 68 Female 156 lb 6/22/2012 Physician Canada
Primary
Concomitant
Hyponatraemia Death 81 Female 6/26/2012 Other Health Professional France
Primary
Secondary
Syncope Hospitalization 11/9/2011 70 Female 7/3/2012 Pharmacist United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/10/2012 Female 7/12/2012 Physician Germany
Primary
Secondary
Concomitant
B-cell Lymphoma Other Serious 11/21/2011 50 Female 132 lb 8/6/2012 Physician Germany
Primary
Concomitant
Suicidal Ideation Life Threatening 4/14/2010 62 Female 190 lb 8/10/2012 Other Health Professional United States
Primary
Secondary
Concomitant

Drug Data