Hydrochlorothiazide combined with Metoprolol Succinate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain Required Intervention 62 Male 165 lb 1/11/2006 United States
Primary
Concomitant
Diarrhoea Other Serious 1/13/2006 Male 227 lb 2/22/2006 Physician Germany
Primary
Concomitant
Menorrhagia Hospitalization 10/2/2005 47 Female 2/15/2006 United States
Primary
Concomitant
Sepsis Hospitalization 2/23/2006 67 Male 188 lb 3/3/2006 Other Health Professional United States
Primary
Concomitant
Angioneurotic Oedema Other Serious 10/2/2005 49 Male 215 lb 12/27/2005 Consumer United States
Primary
Secondary
Concomitant
Pyelonephritis Chronic Hospitalization 7/7/2005 Male 3/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Below Therapeutic Hospitalization 6/1/2005 39 Female 12/14/2005 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 80 Male 227 lb 4/5/2006 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 7/7/2005 81 Male 4/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization 2/6/2006 82 207 lb 3/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Monoparesis Hospitalization 85 Male 5/2/2006 Physician Czech Republic
Primary
Concomitant
Vomiting Life Threatening 7/7/2005 81 Male 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 1/6/2006 Female 5/2/2006 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious 1/13/2006 Male 227 lb 5/11/2006 Physician Germany
Primary
Concomitant
Enterococcal Infection Other Serious 1/1/2006 29 Male 5/15/2006 Physician United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 1/6/2006 74 Female 5/4/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2005 74 Female 5/25/2006 Canada
Primary
Concomitant
Rash Other Serious 2/23/2006 55 Female 6/5/2006 Physician Hungary
Primary
Secondary
Concomitant
Renal Failure Death 4/1/2006 80 Male 6/13/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 4/18/2006 73 Male 216 lb 6/28/2006 Physician United States
Primary
Concomitant
Fall Other Serious 3/23/2006 Male 291 lb 9/7/2006 Physician Germany
Primary
Concomitant
Headache 5/18/2006 76 Female 140 lb 8/23/2006 Physician United States
Primary
Concomitant
Fatigue 10/18/2005 35 Female 167 lb 11/29/2006 Consumer United States
Primary
Secondary
Concomitant
Pancreatic Carcinoma Other Serious 3/28/2006 54 Female 11/20/2006 Consumer United States
Primary
Concomitant
Retching Hospitalization 12/1/2005 Female 140 lb 11/30/2006 Physician United States
Primary
Concomitant
Oedema Due To Cardiac Disease Hospitalization 80 Female 11/24/2006 Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 80 Male 203 lb 12/8/2006 United States
Primary
Concomitant
Weight Increased Hospitalization 2/1/2003 37 Male 320 lb 12/6/2006 Consumer United States
Primary
Concomitant
Syncope Hospitalization 12/4/2006 82 Male 168 lb 12/12/2006 Pharmacist United States
Primary
Secondary
Procedural Complication Life Threatening 12/8/2006 Female 118 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Carotid Artery Stenosis Hospitalization 9/21/2006 56 Male 225 lb 12/20/2006 Physician United States
Primary
Concomitant
Drug Ineffective 7/1/2006 83 Male 9/12/2006 United States
Primary
Concomitant
Weight Decreased Male 12/21/2006 Consumer United States
Primary
Concomitant
Cerebral Infarction Other Serious 5/28/2006 Male 154 lb 12/21/2006 Physician United States
Primary
Concomitant
Fluid Retention Other Serious 12/1/2006 76 Male 142 lb 12/13/2006 Other Health Professional United States
Primary
Concomitant
Peritonitis Hospitalization 11/29/2005 64 Male 209 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/7/2006 59 Female 198 lb 12/12/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2006 73 Male 12/22/2006 Other Health Professional Canada
Primary
Concomitant
Vision Blurred Hospitalization 1/1/1998 49 Female 130 lb 12/18/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/14/2006 52 Male 245 lb 11/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 2/7/2006 59 Female 198 lb 12/20/2006 Other Health Professional Germany
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 12/26/2006 78 Male 215 lb 12/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 10/1/2006 79 Female 1/3/2007 United States
Primary
Concomitant
Insomnia 8/16/2006 56 Female 156 lb 10/11/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 80 Male 203 lb 1/8/2007 United States
Primary
Concomitant
Dysgeusia 1/1/2005 48 Female 195 lb 10/11/2006 Consumer United States
Primary
Concomitant
Somnolence 11/28/2006 83 Male 201 lb 1/5/2007 Physician United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/30/2006 71 Male 1/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 60 Male 1/12/2007
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 73 Female 1/15/2007
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 80 Male 203 lb 1/13/2007 United States
Primary
Concomitant
Tinnitus Other Serious 1/1/2005 58 Female 196 lb 1/18/2007 Physician Netherlands
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/14/2007 87 Female 138 lb 1/19/2007 United States
Primary
Concomitant
Myalgia Other Serious 10/3/2006 Male 1/17/2007 Pharmacist United States
Primary
Concomitant
Glomerulonephritis Proliferative Other Serious 11/1/2005 70 Female 200 lb 1/19/2007 Physician United States
Primary
Concomitant
Tremor Hospitalization 10/18/2006 48 Female 1/22/2007 Consumer United States
Primary
Concomitant
Shock Other Serious 9/15/2006 Male 172 lb 2/6/2007 Physician Germany
Primary
Concomitant
Syncope Other Serious 60 Male 2/6/2007 United States
Primary
Secondary
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Hyperhidrosis Other Serious 77 Male 222 lb 8/17/2006 United States
Primary
Concomitant
Sciatica Other Serious 10/1/2004 60 Male 194 lb 6/14/2005 United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2005 65 Male 226 lb 2/8/2007 Consumer United States
Primary
Concomitant
Platelet Count Decreased Life Threatening 12/29/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Paraesthesia Other Serious 74 Male 180 lb 6/2/2006 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 10/9/2006 72 Male 164 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 12/18/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/29/2007 72 Female 375 lb 2/7/2007 Pharmacist United States
Primary
Concomitant
Sinus Bradycardia Other Serious 73 Female 2/12/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2006 64 Female 160 lb 10/16/2006 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 6/17/2004 72 Female 2/23/2007 Germany
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/24/2006 63 Male 3/9/2007 Germany
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 6/17/2004 72 Female 3/8/2007 Germany
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2004 64 Female 165 lb 7/23/2004 United States
Primary
Concomitant
Glomerulonephritis Proliferative Other Serious 11/1/2005 70 Female 200 lb 3/16/2007 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2006 65 Male 3/16/2007 Physician United States
Primary
Secondary
Renal Impairment Hospitalization 65 Male 3/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Other Serious 1/1/2005 Female 3/20/2007 Consumer Canada
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 3/26/2007 Consumer United States
Primary
Concomitant
Nightmare Hospitalization 84 Male 200 lb 8/21/2004 Other Health Professional United States
Primary
Secondary
Haematemesis Other Serious 5/2/2006 Male 3/27/2007 Germany
Primary
Concomitant
Stridor Disability 1/30/2007 75 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Rash Macular Hospitalization 3/1/2007 Female 3/26/2007 Consumer United States
Primary
Concomitant
Iritis Other Serious Female 4/4/2007 Consumer United States
Primary
Concomitant
Haematemesis Other Serious 5/2/2006 Male 157 lb 4/4/2007 Germany
Primary
Concomitant
Urinary Tract Infection Other Serious 2/15/2007 Female 4/4/2007 Physician Canada
Primary
Concomitant
Initial Insomnia 11/28/2006 45 Female 309 lb 1/12/2007 Consumer United States
Primary
Concomitant
Dysgeusia 11/21/2006 90 Female 132 lb 1/12/2007 Consumer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 3/29/2007 Physician Canada
Primary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 4/6/2007 57 Male 400 lb 4/6/2007 Consumer United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/3/2007 59 Female 187 lb 4/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/21/2007 Female 4/13/2007 Consumer United States
Primary
Concomitant
Gout Hospitalization 2/7/2007 Female 250 lb 4/17/2007 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 12/24/2006 82 Female 128 lb 3/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Coronary Artery Bypass Other Serious 9/1/2006 Female 4/18/2007 United States
Primary
Concomitant
Rash Macular Hospitalization 3/1/2007 73 Female 4/9/2007 Consumer United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 4/16/2007 Female 4/20/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Other Serious 12/5/2005 Male 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 2/1/2007 56 Male 148 lb 4/17/2007 Physician Canada
Primary
Concomitant
Visual Disturbance Hospitalization 4/6/2007 71 Female 189 lb 4/18/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 4/30/2007 Consumer United States
Primary
Secondary
Concomitant
Female Genital Tract Fistula Other Serious 8/30/2005 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/1/2007 Physician Germany
Primary
Concomitant
Loss Of Consciousness Other Serious 3/22/2007 Male 5/2/2007 Physician
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 5/4/2007 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 1/16/2007 83 Male 138 lb 1/17/2007 Pharmacist United States
Primary
Secondary
Loss Of Consciousness Hospitalization 76 Female 5/1/2007
Primary
Concomitant
Wrist Fracture Other Serious Male 5/9/2007 Consumer Canada
Primary
Secondary
Concomitant
Vasospasm Other Serious 1/1/2006 Female 5/11/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Ureterostomy Site Discomfort Life Threatening 9/1/2006 69 Male 198 lb 5/11/2007 Physician Germany
Primary
Concomitant
Pulmonary Oedema Other Serious 3/1/2007 73 Female 5/14/2007 Consumer United States
Primary
Concomitant
Dysuria Other Serious 1/1/2006 Female 161 lb 5/16/2007 Consumer United States
Primary
Concomitant
Septic Shock Life Threatening 9/1/2006 69 Male 198 lb 5/22/2007 Physician Germany
Primary
Concomitant
Mental Status Changes Other Serious 6/9/2006 76 Male 157 lb 12/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 82 Female 166 lb 5/22/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 12/14/2005 78 Female 180 lb 12/13/2006 Consumer United States
Primary
Concomitant
Glomerulonephritis Proliferative Other Serious 11/1/2005 70 Female 200 lb 5/25/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 2/1/2007 84 Female 5/30/2007 Physician United States
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 11/7/2006 41 Male 179 lb 5/30/2007 Physician Netherlands
Primary
Concomitant
Coronary Artery Disease Hospitalization 9/24/2006 63 Male 6/1/2007 Germany
Primary
Secondary
Concomitant
Urticaria Other Serious 10/1/2006 77 Female 134 lb 4/30/2007 Pharmacist United States
Primary
Concomitant
Leukocytosis 5/23/2007 60 Male 169 lb 5/31/2007 Pharmacist United States
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Hospitalization 71 6/8/2007 Germany
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/14/2005 Female 146 lb 6/6/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 3/9/2005 74 Female 126 lb 6/6/2007 Lawyer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 6/1/2002 63 Male 269 lb 6/12/2007 Consumer United States
Primary
Concomitant
Renal Impairment Hospitalization 65 Male 6/12/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/28/2007 Female 154 lb 6/12/2007 Poland
Primary
Concomitant
Swollen Tongue Other Serious 6/7/2007 Male 328 lb 6/8/2007 Pharmacist United States
Primary
Secondary
Concomitant
Increased Upper Airway Secretion 1/1/2006 79 Male 185 lb 6/22/2007 Consumer United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Sciatica 10/1/2004 60 Male 194 lb 6/25/2007 United States
Primary
Concomitant
Feeling Abnormal 10/20/2006 65 Male 195 lb 6/25/2007 Consumer United States
Primary
Concomitant
Postoperative Wound Infection Hospitalization 205 lb 6/25/2007 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 8/3/2006 68 Male 225 lb 11/21/2006 Physician Germany
Primary
Secondary
Concomitant
Nephritis Interstitial Hospitalization 1/12/2007 51 Male 123 lb 6/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 50 Male 6/28/2007 Consumer United States
Primary
Secondary
Concomitant
Open Wound Other Serious 5/1/2004 46 Male 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 6/28/2007 Physician Canada
Primary
Concomitant
Vomiting Other Serious 10/1/2006 58 Female 220 lb 6/13/2007 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2007 84 Female 169 lb 7/14/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 82 Female 166 lb 7/13/2007 Consumer United States
Primary
Concomitant
Renal Impairment Other Serious 5/1/2007 Male 7/17/2007 Physician Canada
Primary
Concomitant
Blood Glucose Decreased Other Serious 69 Male 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/1/2007 Female 223 lb 7/20/2007 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/1/2007 56 Male 148 lb 7/18/2007 Physician Canada
Primary
Concomitant
Renin Decreased Other Serious 50 Female 190 lb 7/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/1/2006 Female 161 lb 7/25/2007 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 2/27/2007 Female 139 lb 7/27/2007 Germany
Primary
Secondary
Concomitant
Renal Failure Other Serious 82 Male 161 lb 7/30/2007 Physician Germany
Primary
Secondary
Concomitant

Drug Data