Hydrochlorothiazide combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Fat Tissue Increased Hospitalization 12/15/2003 53 Female 1/25/2006 Netherlands
Primary
Concomitant
Heart Rate Increased Other Serious 1/1/2003 53 Female 2/7/2006 Consumer Canada
Primary
Concomitant
Skin Discolouration Other Serious 12/12/2005 66 Female 146 lb 2/9/2006 Physician United States
Primary
Concomitant
Pneumonia Death 12/25/2005 57 Male 235 lb 2/14/2006 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Other Serious 11/9/2004 56 Female 187 lb 3/7/2006 Lawyer United States
Primary
Concomitant
Psoriasis 8/1/2005 48 Female 276 lb 1/20/2006 Consumer United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 1/15/2006 Female 154 lb 4/12/2006 Other Health Professional Netherlands
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Cold Sweat Other Serious 3/21/2006 57 Male 324 lb 3/21/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 11/9/2004 56 Female 187 lb 5/3/2006 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 5/1/2004 73 Male 194 lb 6/19/2006 Consumer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/1/2005 78 Male 202 lb 7/21/2006 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Diarrhoea 1/1/2005 77 Female 220 lb 8/1/2006 Consumer United States
Primary
Concomitant
Urinary Tract Infection Death 4/10/2004 64 Male 8/2/2006 Pharmacist
Primary
Concomitant
Rash Other Serious 6/30/2006 66 Male 208 lb 6/30/2006 Pharmacist United States
Primary
Concomitant
Fatigue 3/21/2006 50 Female 260 lb 7/11/2006 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 10/28/2004 49 Male 9/26/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 8/7/2006 77 Male 236 lb 10/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
High Density Lipoprotein Decreased Other Serious 55 Male 159 lb 10/6/2006 Canada
Primary
Concomitant
Renal Tubular Necrosis Other Serious 56 Female 10/10/2006 Physician United States
Primary
Concomitant
Renal Failure Acute Life Threatening 6/10/2006 79 Female 196 lb 11/1/2006 Other Health Professional France
Primary
Secondary
Concomitant
Dizziness Other Serious 3/1/2006 49 Male 11/9/2006 Consumer United States
Primary
Secondary
Concomitant
Breast Cancer In Situ Hospitalization 12/7/2005 Female 12/13/2006 Physician United States
Primary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 3/16/2006 65 Male 198 lb 3/23/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 69 Male 3/19/2007 Physician Norway
Primary
Concomitant
Pupillary Reflex Impaired Hospitalization 49 Female 3/19/2007 Norway
Primary
Concomitant
Respiratory Disorder Hospitalization 69 Female 3/20/2007 Physician Norway
Primary
Concomitant
Vomiting Hospitalization 81 Female 3/20/2007 Norway
Primary
Concomitant
Vomiting Life Threatening 81 Female 4/2/2007 Physician Norway
Primary
Secondary
Concomitant
Urine Albumin/creatinine Ratio Increased Other Serious 3/16/2006 65 Male 198 lb 4/24/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 55 Male 5/9/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 5/23/2006 52 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Hypoglycaemia Other Serious 1/15/2006 61 Male 4/26/2007 United States
Primary
Secondary
Concomitant
Hyperglycaemia Other Serious 64 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Patella Fracture Hospitalization 6/26/2007 48 Female 207 lb 8/27/2007 Physician Canada
Primary
Concomitant
Nail Disorder Female 195 lb 9/12/2007 United States
Primary
Concomitant
Patella Fracture Hospitalization 6/26/2007 48 Female 207 lb 9/20/2007 Physician Canada
Primary
Concomitant
Blood Glucose Increased Other Serious 10/1/2007 Female 138 lb 11/20/2007 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 81 Female 1/2/2008 Physician Norway
Primary
Secondary
Ventricular Fibrillation Hospitalization 10/1/2007 71 Female 161 lb 3/20/2008 Physician Germany
Primary
Concomitant
Urinary Incontinence Other Serious Male 6/11/2008 Consumer Brazil
Primary
Concomitant
Transient Ischaemic Attack Required Intervention 11/30/2002 66 Female 97 lb 6/17/2008 United States
Primary
Concomitant
Incorrect Dose Administered Other Serious 9/1/2006 60 Female 242 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 50 Female 6/27/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 50 Female 7/28/2008 Physician United States
Primary
Concomitant
Dyspnoea 1/1/2008 65 Female 250 lb 7/7/2008 Consumer United States
Primary
Concomitant
Death Death 6/1/2008 64 Male 9/2/2008 Physician Norway
Primary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/18/2008 Physician Norway
Primary
Concomitant
Sudden Death Death 6/1/2008 64 Male 9/25/2008 Physician Norway
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 50 Female 10/7/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/10/2008 Male 182 lb 10/10/2008 Physician United States
Primary
Concomitant
Hyponatraemia Other Serious 1/1/2008 61 Male 10/20/2008 Pharmacist Australia
Primary
Concomitant
Pancreatitis Other Serious 8/1/2008 Male 244 lb 10/17/2008 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2008 Female 187 lb 10/17/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 46 Female 390 lb 10/20/2008 United States
Primary
Secondary
Concomitant
Underdose Hospitalization 10/13/2008 81 Male 10/17/2008 Other Health Professional United States
Primary
Concomitant
Myoclonus Hospitalization 46 Female 390 lb 10/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis 5/16/2008 Male 12/12/2008 Other Health Professional United States
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 8/28/2008 Female 266 lb 12/17/2008 Physician United States
Primary
Concomitant
Osteoarthritis Hospitalization 9/25/2008 12/24/2008 Physician Brazil
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2008 Male 140 lb 12/29/2008 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 9/25/2008 12/31/2008 Physician Brazil
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 50 Female 12/30/2008 Physician United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 72 Male 1/21/2009 Other Health Professional Netherlands
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 1/1/2008 Male 140 lb 2/3/2009 Consumer United States
Primary
Concomitant
Blood Pressure Increased 11/15/2008 62 Female 291 lb 2/16/2009 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 3/10/2008 4/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Renal Failure Other Serious 3/10/2008 Female 287 lb 4/20/2009 Other Health Professional Netherlands
Primary
Concomitant
Wrong Technique In Drug Usage Process 9/1/2008 72 Female 5/15/2009 United States
Primary
Concomitant
Hemiparesis Hospitalization 2/28/2009 47 Male 238 lb 5/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2008 64 Male 4/24/2009 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/5/2006 61 Male 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 9/1/2006 73 Female 160 lb 6/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Paralysis Hospitalization 1/1/2002 42 Male 150 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Transaminases Increased Hospitalization 3/7/2009 64 Female 141 lb 5/29/2009 United States
Primary
Secondary
Concomitant
Pain Hospitalization 1/30/2006 50 Male 211 lb 6/5/2009 Lawyer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/15/2004 66 Female 250 lb 6/5/2009 Physician United States
Primary
Concomitant
Coronary Artery Bypass Hospitalization 5/26/2009 Male 6/5/2009 Canada
Primary
Concomitant
Dysphonia Hospitalization 1/1/2006 71 Male 228 lb 6/8/2009 Other Health Professional United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Hospitalization 5/1/2009 Female 5/27/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 46 Male 250 lb 6/10/2009 United States
Primary
Concomitant
Pain Female 304 lb 6/12/2009 United States
Primary
Concomitant
Drug Dose Omission 5/5/2009 Female 125 lb 6/12/2009 Consumer United States
Primary
Concomitant
Shock Hospitalization 11/1/2006 58 Female 6/15/2009 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/2/2004 51 Female 250 lb 6/15/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1993 54 Female 7/10/2009 United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 8/2/2009 66 Male 247 lb 8/6/2009 Consumer United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 7/17/2009 Male 8/12/2009 Other Health Professional Portugal
Primary
Concomitant
Vision Blurred Other Serious 7/17/2009 Male 8/13/2009 Other Health Professional India
Primary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 8/21/2009 Other Health Professional United States
Primary
Secondary
Erythema Male 8/22/2009 United States
Primary
Concomitant
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 8/26/2009 Other Health Professional United States
Primary
Secondary
Sudden Death Death 7/17/2009 76 Female 8/27/2009 United States
Primary
Secondary
Myocardial Infarction Death 7/17/2009 76 Female 8/31/2009 United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 201 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2009 76 Female 9/4/2009 United States
Primary
Secondary
Myocardial Infarction Death 7/17/2009 76 Female 201 lb 9/8/2009 Other Health Professional United States
Primary
Secondary
Nausea Female 9/28/2009 United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 5/1/2004 46 Female 226 lb 9/30/2009 Pharmacist United States
Primary
Concomitant
Eye Haemorrhage Other Serious 73 Female 168 lb 10/1/2009 Consumer United States
Primary
Concomitant
Haemorrhagic Anaemia Other Serious 8/21/2009 71 Male 10/12/2009 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2009 Female 146 lb 10/13/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 6/30/2009 78 Female 161 lb 8/31/2009 Pharmacist United States
Primary
Concomitant
Ill-defined Disorder Disability Female 236 lb 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Female 263 lb 10/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ill-defined Disorder Disability Male 229 lb 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Male 229 lb 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Male 205 lb 10/15/2009 United States
Primary
Concomitant
Ill-defined Disorder Disability Male 194 lb 10/15/2009 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder Disability 242 lb 10/15/2009 United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/9/2006 54 Male 263 lb 10/15/2009 Other Health Professional United States
Primary
Concomitant
Ill-defined Disorder Disability Male 223 lb 10/16/2009 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2005 Male 10/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tachyarrhythmia Hospitalization 6/27/2009 Female 151 lb 10/19/2009 United States
Primary
Concomitant
Muscle Rupture Hospitalization Male 10/15/2009 Physician Netherlands
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 11/11/2009 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 12/3/2009 Other Health Professional France
Primary
Secondary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 8/1/2008 78 Male 250 lb 12/22/2009 Physician United States
Primary
Concomitant
Microalbuminuria Other Serious 12/1/2009 Male 1/6/2010 Physician Canada
Primary
Concomitant
Psychotic Disorder Other Serious 34 Female 12/23/2009 Other Health Professional United States
Primary
Concomitant
Angioedema Required Intervention 59 Female 12/22/2009 Physician Thailand
Primary
Concomitant
Uterine Haemorrhage Other Serious 12/1/2005 Female 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Uveitis Other Serious 2/5/2008 Male 175 lb 1/11/2010 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 53 Male 1/12/2010 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Other Serious 5/12/2009 48 Male 1/12/2010 Pharmacist Netherlands
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Uterine Haemorrhage Other Serious 7/1/2004 Female 1/14/2010 Physician United States
Primary
Secondary
Concomitant
Swelling Other Serious 1/1/2010 Female 155 lb 1/27/2010 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/2/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/8/2010 Other Health Professional France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 2/16/2010 Other Health Professional France
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 2/18/2010 Physician United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Life Threatening 12/27/2009 61 Male 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Hip Fracture Other Serious 9/1/2009 Female 2/25/2010 Consumer Canada
Primary
Concomitant
Rash Pruritic Hospitalization 12/18/2009 Female 198 lb 3/3/2010 Consumer United States
Primary
Concomitant
Urticaria 2/13/2010 60 Male 3/3/2010 Consumer
Primary
Concomitant
Rectal Haemorrhage Hospitalization 2/28/2010 69 Female 146 lb 3/1/2010 Physician United States
Primary
Secondary
Concomitant
Sinusitis Hospitalization 1/1/2009 74 Female 3/1/2010 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 8/1/2008 78 Male 250 lb 3/9/2010 Physician United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 65 Male 223 lb 3/11/2010 Consumer United States
Primary
Concomitant
Weight Increased 58 Male 3/11/2010 Consumer United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Life Threatening 10/1/2006 Male 250 lb 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/1/2009 65 Female 227 lb 3/11/2010 Other Health Professional France
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 12/29/2009 Female 3/9/2010 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Death 72 Male 3/16/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 57 Female 3/16/2010 Consumer United States
Primary
Secondary
Concomitant
Sudden Death Death 7/17/2009 76 Female 201 lb 3/17/2010 Other Health Professional United States
Primary
Secondary

Drug Data