Hydrochlorothiazide combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transient Ischaemic Attack Other Serious 77 Female 150 lb 1/5/2006 United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 12/13/2003 82 Male 1/11/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 190 lb 1/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/12/2006 89 1/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 10/1/2003 70 Male 6/30/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 11/21/2005 48 Female 173 lb 1/12/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 220 lb 1/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ankle Fracture Other Serious 8/1/2005 Female 281 lb 1/24/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 11/2/2005 71 Male 1/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased 1/1/2004 75 Female 161 lb 1/30/2006 Consumer United States
Primary
Concomitant
Dizziness 12/4/2005 65 Female 170 lb 1/30/2006 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2003 45 Female 256 lb 1/30/2006 Consumer United States
Primary
Secondary
Concomitant
Shock Other Serious 7/13/2005 60 Female 1/23/2006 Consumer United States
Primary
Concomitant
Localised Infection Hospitalization 12/31/2005 71 Male 2/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 1/16/2006 52 Male 1/27/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/25/2005 61 Male 2/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/11/2005 50 Male 240 lb 2/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/14/2006 Physician South Africa
Primary
Concomitant
Renal Failure Death 12/25/2005 57 Male 235 lb 2/24/2006 Other Health Professional United States
Primary
Concomitant
Subdural Haemorrhage Hospitalization 8/1/2005 58 Male 160 lb 2/24/2006 Physician South Africa
Primary
Concomitant
Pneumonia Life Threatening 1/19/2006 60 Male 260 lb 3/7/2006 Other Health Professional United States
Primary
Concomitant
Urine Ketone Body Present Hospitalization 3/26/2005 67 Female 159 lb 3/8/2006 Physician United States
Primary
Concomitant
Neutropenia Other Serious 2/22/2005 38 Male 245 lb 4/1/2005 Pharmacist United States
Primary
Concomitant
Synovial Cyst Other Serious 1/1/2005 78 Female 174 lb 3/20/2006 United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 1/1/2001 58 Male 203 lb 4/7/2006 United States
Primary
Concomitant
Insomnia 11/15/2005 66 Male 4/3/2006 Consumer United States
Primary
Concomitant
Muscle Spasms 3/9/2006 59 Female 250 lb 4/17/2006 Consumer United States
Primary
Concomitant
Shock Hospitalization 5/3/2006 65 Male 362 lb 6/1/2006 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2006 70 Female 6/9/2006 Consumer United States
Primary
Concomitant
Tumour Necrosis Other Serious 11/1/2005 79 Male 160 lb 6/16/2006 United States
Primary
Concomitant
Tremor Life Threatening 5/3/2006 49 Male 190 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemic Seizure Life Threatening 5/9/2006 49 Male 190 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 5/1/2004 73 Male 194 lb 6/19/2006 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased 77 Female 5/24/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/21/2006 Female 110 lb 8/8/2006 Physician Canada
Primary
Concomitant
Weight Decreased Life Threatening 5/30/2006 65 Male 344 lb 8/4/2006 Physician United States
Primary
Concomitant
Leukopenia Required Intervention 9/27/2005 42 Female 328 lb 2/3/2006 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 8/7/2006 56 Male 222 lb 8/18/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/16/2006 65 Female 196 lb 8/28/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/14/2004 72 Male 170 lb 8/23/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased 5/1/2006 63 Female 287 lb 7/21/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 2/21/2006 47 Female 208 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 12/1/2005 56 Male 186 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 5/10/2006 67 Male 265 lb 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 60 Male 7/19/2006 Other Health Professional United States
Primary
Concomitant
Vomiting 76 Female 7/19/2006 Consumer United States
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 9/4/2006 Male 9/18/2006 Pharmacist Canada
Primary
Concomitant
Stomach Discomfort 6/5/2006 65 Female 280 lb 7/19/2006 Consumer United States
Primary
Concomitant
Snoring Life Threatening 6/26/2006 52 Female 306 lb 8/31/2006 Pharmacist United States
Primary
Concomitant
Vomiting 6/4/2006 35 Female 180 lb 7/19/2006 Consumer United States
Primary
Concomitant
Nausea Hospitalization 9/25/2006 44 Male 283 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased 8/1/2006 Male 205 lb 10/2/2006 Consumer United States
Primary
Concomitant
Somnolence Other Serious 66 Female 162 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Hospitalization 8/11/2006 63 Female 245 lb 9/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 5/3/2006 65 Male 344 lb 9/29/2006 Physician United States
Primary
Concomitant
Drug Ineffective 5/26/2006 61 Male 7/19/2006 Consumer United States
Primary
Concomitant
Ph Body Fluid Decreased Hospitalization 7/20/2006 64 Female 9/28/2006 Spain
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 9/23/2006 58 Male Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 9/19/2006 73 Male Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 10/15/2006 62 Female 230 lb 10/16/2006 Other Health Professional United States
Primary
Concomitant
Dysgeusia 4/1/2006 75 Male 8/22/2006 United States
Primary
Concomitant
Nausea Hospitalization 10/7/2005 54 Female 10/17/2006 Physician United States
Primary
Concomitant
Blood Glucose Decreased Other Serious 8/31/2005 74 Male 8/21/2006 Pharmacist United States
Primary
Concomitant
Hyponatraemia Hospitalization 9/1/2006 43 Male 253 lb 10/26/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 9/26/2006 86 Male 10/30/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Lethargy Hospitalization 9/26/2006 45 Female 10/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/23/2006 74 Male 190 lb 11/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 56 Female 10/25/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 1/1/2006 69 Male 145 lb 10/12/2006 Physician Canada
Primary
Concomitant
Gastritis Hospitalization 7/25/2005 54 Female 11/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased 5/1/2003 75 Female 11/30/2006 Other Health Professional United States
Primary
Concomitant
Guillain-barre Syndrome Hospitalization 9/4/2006 Male 206 lb 12/5/2006 Pharmacist Canada
Primary
Concomitant
Constipation 2/1/2006 81 Female 9/12/2006 Physician United States
Primary
Concomitant
Non-cardiac Chest Pain Hospitalization 11/14/2006 69 Male 202 lb 12/1/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/27/2006 66 Female 10/27/2006 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 11/13/2006 57 Male 11/21/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 69 Female 12/20/2006 Other Health Professional Norway
Primary
Secondary
Visual Disturbance Life Threatening 69 Male 12/21/2006 Other Health Professional Norway
Primary
Secondary
Hypoglycaemia Hospitalization 9/27/2006 66 Female 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Shock Life Threatening 7/5/2005 77 Male 12/26/2006 Consumer Germany
Primary
Secondary
Concomitant
Sneezing 4/27/2006 57 Female 12/28/2006 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/22/2006 68 Female 205 lb 12/22/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 9/28/2006 Female 185 lb 12/29/2006 Physician United States
Primary
Concomitant
Rash Other Serious 64 Female 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2006 Female 250 lb 1/4/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 3/1/2004 Male 165 lb 1/4/2007 Physician United States
Primary
Concomitant
Middle Insomnia 1/1/2006 54 Female 155 lb 10/11/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 8/1/2006 55 Male 10/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious Female 1/9/2007 Consumer Brazil
Primary
Secondary
Concomitant
Oedema Peripheral 67 Female 265 lb 10/19/2006 United States
Primary
Concomitant
Sensation Of Heaviness Other Serious Female 1/12/2007 Consumer Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 8/1/2005 43 Male 185 lb 10/4/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2005 79 Female 11/28/2006 Physician United States
Primary
Concomitant
Myalgia Other Serious 10/27/2006 Male 1/16/2007 Pharmacist United States
Primary
Concomitant
Myalgia Other Serious 10/3/2006 Male 1/17/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 8/22/2006 68 Female 205 lb 1/12/2007 Other Health Professional United States
Primary
Concomitant
Sensation Of Heaviness Other Serious Female 1/23/2007 Consumer Brazil
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 7/17/2006 46 Male 258 lb 11/28/2006 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2000 46 Female 197 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Nausea Hospitalization 8/1/2006 Female 191 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 81 Female 1/29/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Weight Decreased 7/1/2006 55 Female 332 lb 10/16/2006 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 69 Male 1/25/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 1/25/2007 Other Health Professional Norway
Primary
Concomitant
Respiratory Failure Hospitalization 69 Female 1/22/2007 Norway
Primary
Secondary
Concomitant
Vomiting Hospitalization 81 Female 1/22/2007 Norway
Primary
Secondary
Concomitant
Renal Failure Hospitalization 49 Female 1/22/2007 Norway
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization 69 Male 1/22/2007 Norway
Primary
Secondary
Concomitant
Thinking Abnormal 4/1/2006 Female 11/10/2006 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 2/1/2007 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/1/2006 54 Female 247 lb 1/25/2007 Consumer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 10/1/2006 75 Female 1/29/2007 Pharmacist Netherlands
Primary
Secondary
Concomitant
Drug Effect Decreased 9/10/2006 61 Female 202 lb 10/16/2006 Consumer United States
Primary
Concomitant
Tension 4/15/2006 84 Male 2/6/2007 Consumer United States
Primary
Secondary
Concomitant
Shock Other Serious 9/15/2006 Male 172 lb 2/6/2007 Physician Germany
Primary
Concomitant
Rectal Haemorrhage Other Serious 81 Female 2/6/2007 Other Health Professional Norway
Primary
Secondary
Concomitant
Vomiting 9/1/2006 68 Female 245 lb 10/16/2006 Consumer United States
Primary
Concomitant
Injection Site Irritation 9/17/2006 67 Female 207 lb 10/16/2006 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 10/1/2006 61 Male 250 lb 2/2/2007 United States
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 69 Female 2/7/2007 Other Health Professional Norway
Primary
Secondary
Renal Failure Life Threatening 69 Male 2/7/2007 Other Health Professional France
Primary
Secondary
Metabolic Encephalopathy Hospitalization 8/14/2006 80 Male 2/2/2007 Other Health Professional United States
Primary
Concomitant
Wound Haemorrhage Hospitalization 1/1/2004 54 Male 2/2/2007 Other Health Professional Canada
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 62 Female 180 lb 6/2/2006 United States
Primary
Concomitant
Hyperhidrosis Other Serious 77 Male 222 lb 8/17/2006 United States
Primary
Concomitant
White Blood Cells Stool Positive Hospitalization 8/8/2006 68 Female 205 lb 2/7/2007 Other Health Professional United States
Primary
Concomitant
Myalgia Other Serious 61 Male 300 lb 6/14/2005 United States
Primary
Concomitant
Aplasia Pure Red Cell Other Serious 1/25/2007 Male 211 lb 2/13/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/1/2007 56 Male 2/9/2007 Physician France
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 8/1/2005 63 Female 11/17/2005 United States
Primary
Concomitant
Weight Decreased 3/1/2006 74 Male 10/16/2006 Consumer United States
Primary
Concomitant
Hyperglycaemia Hospitalization 10/4/2006 58 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 2/20/2007 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 6/1/2006 66 Male 2/13/2007 United States
Primary
Concomitant
Sudden Hearing Loss Other Serious 11/17/2006 Male 203 lb 2/23/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 81 Female 2/27/2007
Primary
Secondary
Renal Failure Acute Other Serious 69 Female 2/27/2007
Primary
Secondary
Renal Failure Other Serious 11/1/2005 Male 308 lb 2/12/2007 Physician United States
Primary
Concomitant
Dyspnoea 4/1/2006 83 Female 139 lb 2/27/2007 Consumer United States
Primary
Concomitant
Sexual Dysfunction 1/1/2006 63 Male 2/27/2007 Consumer United States
Primary
Secondary
Rash 1/6/2006 59 Female 2/28/2007 Consumer United States
Primary
Concomitant
Weight Decreased 5/1/2006 68 Female 200 lb 10/16/2006 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/30/2007 60 Female 141 lb 2/28/2007 Other Health Professional United States
Primary
Concomitant
Erectile Dysfunction Male 11/30/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/17/2007 62 Female 239 lb 3/7/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 2/7/2007 58 Female 3/8/2007 Other Health Professional
Primary
Secondary
Concomitant
Rash Other Serious 64 Female 3/8/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/15/2006 61 Male 250 lb 3/9/2007 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/21/2006 Female 110 lb 3/9/2007 Physician Canada
Primary
Concomitant
Tremor 8/25/2006 59 Female 12/5/2006 United States
Primary
Concomitant

Drug Data