Hydrochlorothiazide combined with Levothyroxine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vision Blurred 5/11/2006 81 Male 7/31/2006 Consumer United States
Primary
Concomitant
Urticaria 7/1/2008 Female 170 lb 8/27/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/31/2007 Female 290 lb 8/26/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2006 Female 200 lb 8/29/2008 Physician United States
Primary
Secondary
Concomitant
Syncope 11/1/2007 63 Male 165 lb 7/28/2008 United States
Primary
Concomitant
Drug Ineffective 11/1/2008 Female 12/30/2008 Consumer
Primary
Concomitant
Visual Impairment Life Threatening 65 Male 238 lb 12/20/2008 Physician United States
Primary
Concomitant
Overdose Death 12/1/2008 32 Male 1/7/2009 Other Health Professional United States
Primary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/8/2009 Physician United States
Primary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/9/2009 Physician United States
Primary
Concomitant
Occult Blood Positive Hospitalization 9/9/2008 64 Female 284 lb 1/13/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/21/2009 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious Male 1/20/2009 Physician United States
Primary
Secondary
Concomitant
Angina Unstable Hospitalization 7/5/2001 Male 194 lb 1/21/2009 Physician United States
Primary
Concomitant
Angina Unstable Other Serious 7/9/2001 Male 194 lb 1/24/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 1/27/2009 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 10/1/2003 Male 200 lb 2/3/2009 Consumer United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2003 63 Male 2/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2003 2/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious Male 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 2/12/2008 71 Female 3/5/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 3/13/2009 Consumer United States
Primary
Secondary
Concomitant
Urine Colour Abnormal 2/4/2009 Female 205 lb 3/16/2009 Physician United States
Primary
Concomitant
Thyroid Disorder Other Serious 1/1/2001 Male 3/17/2009 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/31/2008 Female 3/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 9/26/1995 Female 141 lb 3/30/2009 Lawyer United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 5/19/2009 Female 157 lb 5/25/2009 Physician United States
Primary
Concomitant
Restless Legs Syndrome Female 6/1/2009 Physician
Primary
Concomitant
Incorrect Dose Administered 3/3/2009 Female 232 lb 6/11/2009 Consumer United States
Primary
Concomitant
Drug Dose Omission 2/1/2009 Male 285 lb 6/12/2009 Consumer United States
Primary
Concomitant
Stomatitis 5/1/2009 Female 150 lb 6/12/2009 United States
Primary
Concomitant
Lacrimation Increased Hospitalization 11/1/2008 73 Female 233 lb 7/13/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 7/16/2009 Other Health Professional Brazil
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 7/27/2009 Other Health Professional Brazil
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 8/4/2009 Brazil
Primary
Concomitant
Epistaxis Other Serious 7/1/2009 73 Male 126 lb 8/6/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/2/2007 64 Male 272 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 72 Female 7/30/2009 United States
Primary
Concomitant
Nausea Hospitalization 6/11/2009 87 Female 159 lb 8/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/2/2007 64 Male 272 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization Male 8/20/2009 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 72 Female 8/14/2009 United States
Primary
Concomitant
Pruritus Female 8/21/2009 United States
Primary
Concomitant
Flushing 9/7/2008 66 Male 8/21/2009 Consumer United States
Primary
Concomitant
Skin Burning Sensation 8/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 6/10/2009 71 Female 8/24/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 3/5/2003 71 Female 8/18/2009 United States
Primary
Concomitant
Breast Cancer Female Other Serious 12/18/2002 Female 119 lb 8/27/2009 Consumer United States
Primary
Secondary
Concomitant
Swollen Tongue Hospitalization 8/1/2009 Female 8/26/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 8/27/2009 Other Health Professional Brazil
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/5/2009 89 Female 8/27/2009 Pharmacist United States
Primary
Concomitant
No Therapeutic Response Required Intervention 1/17/2009 74 Female 9/28/2009 Pharmacist United States
Primary
Secondary
Concomitant
Heart Rate Irregular 8/17/2009 90 Male 9/10/2009 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 7/4/2009 65 10/30/2009 Other Health Professional Brazil
Primary
Concomitant
Chills Other Serious 7/21/2008 74 Female 173 lb 11/6/2008 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 3/5/2003 71 Female 11/9/2009 Lawyer United States
Primary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 11/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 11/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Breast Cancer Female Other Serious 9/26/1995 Female 141 lb 11/27/2009 Lawyer United States
Primary
Secondary
Concomitant
Paralysis Other Serious 86 Female 12/1/2009 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 12/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 1/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 1/1/2009 Female 2/26/2010 United States
Primary
Concomitant
Tinnitus 11/1/2009 49 Female 1/28/2010 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 10/29/2009 68 Female 11/12/2009 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/13/2009 82 Female 12/8/2009 Pharmacist United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Sternal Fracture Other Serious 1/1/2008 Female 186 lb 3/4/2010 Consumer United States
Primary
Concomitant
Wisdom Teeth Removal Other Serious 2/1/2005 Female 165 lb 3/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wisdom Teeth Removal Other Serious 2/1/2005 Female 165 lb 3/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Male 244 lb 4/9/2010 Physician United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/21/2010 60 Male 267 lb 4/16/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/18/2010 Female 206 lb 4/19/2010 Physician United States
Primary
Concomitant
Sternal Fracture Other Serious 1/1/2008 68 Female 186 lb 4/20/2010 Consumer United States
Primary
Concomitant
Mobility Decreased Other Serious 11/1/2009 85 Male 4/22/2010 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 3/19/2010 61 Female 206 lb 4/23/2010 Physician United States
Primary
Concomitant
Gastric Ulcer Hospitalization 12/1/2009 88 Female 161 lb 5/3/2010 Consumer United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 3/1/2009 64 Female 5/3/2010 United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease Female 190 lb 5/3/2010 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 5/4/2010 Physician Argentina
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/28/2010 56 Female 5/4/2010 United States
Primary
Secondary
Concomitant
Sternal Fracture Other Serious 1/1/2008 68 Female 186 lb 5/28/2010 Physician United States
Primary
Concomitant
Weight Increased Other Serious 11/1/2009 74 Male 368 lb 6/18/2010 Consumer United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 22 Male 450 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Septic Shock Other Serious 7/6/2009 68 Female 154 lb 6/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 11/25/2008 76 Male 192 lb 7/12/2010 Physician Canada
Primary
Concomitant
Terminal Insomnia 1/1/2007 72 Female 160 lb 7/12/2010 Consumer United States
Primary
Concomitant
Diarrhoea 3/23/2007 61 Male 187 lb 7/12/2010 Consumer United States
Primary
Concomitant
Urticaria 3/1/2007 52 Male 247 lb 7/13/2010 Consumer United States
Primary
Concomitant
Renal Tubular Atrophy Other Serious 2/18/2008 56 Female 294 lb 7/12/2010 Lawyer United States
Primary
Concomitant
Dizziness 3/30/2010 75 Female 148 lb 5/20/2010 Consumer United States
Primary
Concomitant
Breast Cancer Female Other Serious 1/1/2001 57 Female 7/21/2010 Lawyer United States
Primary
Concomitant
Suicide Attempt Other Serious 6/1/2007 51 Male 7/23/2010 Lawyer United States
Primary
Concomitant
Skin Injury Other Serious 2/28/2007 44 Male 7/23/2010 Lawyer United States
Primary
Concomitant
Headache Other Serious 5/30/2010 55 Female 175 lb 7/23/2010 Consumer United States
Primary
Concomitant
Vomiting 2/13/2009 62 Female 170 lb 7/29/2010 Consumer United States
Primary
Concomitant
Urinary Tract Disorder Female 146 lb 8/3/2010 Other Health Professional United States
Primary
Concomitant
Vision Blurred 5/1/2008 79 Female 8/3/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2009 57 Female 180 lb 8/3/2010 Physician United States
Primary
Concomitant
Weight Increased 1/1/2009 67 Female 215 lb 8/4/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Off Label Use Other Serious 1/1/2010 54 Male 8/4/2010 Consumer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 78 Male 175 lb 8/9/2010 Other Health Professional United States
Primary
Concomitant
Vessel Puncture Site Haematoma Other Serious 3/1/2008 45 Female 8/9/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 8/10/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 66 Male 8/10/2010 Consumer United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/11/2010 Lawyer United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 2/1/2007 65 Female 157 lb 8/11/2010 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 3/17/2008 82 Female 174 lb 8/11/2010 Lawyer United States
Primary
Concomitant
Rash Hospitalization 6/28/2007 57 Female 258 lb 8/12/2010 Physician United States
Primary
Concomitant
Urine Output Decreased Other Serious 1/1/2009 48 Female 8/13/2010 Lawyer United States
Primary
Secondary
Concomitant
Flatulence 7/10/2010 85 Female 8/16/2010 Consumer
Primary
Concomitant
Staphylococcal Sepsis Hospitalization Male 8/16/2010 Other Health Professional United States
Primary
Concomitant
Rash 5/1/2010 69 Female 155 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
Flushing Female 125 lb 8/16/2010 Consumer United States
Primary
Concomitant
Vertigo Other Serious 62 Female 182 lb 8/16/2010 Lawyer United States
Primary
Concomitant
Panic Attack Other Serious 1/1/2008 40 Female 211 lb 8/24/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/1/2009 59 Female 199 lb 8/20/2010 Physician United States
Primary
Concomitant
Pruritus 9/1/2008 76 Female 120 lb 8/27/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation 9/17/2009 67 Female 218 lb 8/27/2010 United States
Primary
Concomitant
Skin Burning Sensation 10/15/2009 51 Female 203 lb 8/28/2010 Consumer United States
Primary
Secondary
Concomitant
Paraesthesia Female 224 lb 8/28/2010 United States
Primary
Concomitant
Muscle Spasms 5/1/2009 75 Female 150 lb 8/28/2010 United States
Primary
Concomitant
Feeling Hot 11/5/2009 66 Female 8/28/2010 United States
Primary
Concomitant
Pruritus 2/6/2010 60 Male 8/28/2010 United States
Primary
Concomitant
Flushing Male 199 lb 8/28/2010 United States
Primary
Concomitant
Flushing Male 206 lb 8/28/2010 United States
Primary
Concomitant
Flushing 1/1/2009 63 Female 200 lb 8/28/2010 Consumer United States
Primary
Concomitant
Flushing 3/16/2010 51 Male 220 lb 8/28/2010 Consumer United States
Primary
Concomitant
Pruritus Female 190 lb 8/28/2010 United States
Primary
Concomitant
Sensory Disturbance 4/29/2010 48 Female 290 lb 8/29/2010 United States
Primary
Concomitant
Flushing Male 213 lb 8/29/2010 Consumer United States
Primary
Concomitant
Skin Burning Sensation Female 142 lb 8/29/2010 Consumer United States
Primary
Concomitant
Pruritus 1/1/2008 67 Female 180 lb 8/29/2010 Consumer United States
Primary
Concomitant
Hypotension Hospitalization 61 Female 8/30/2010 Consumer United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 53 Male 282 lb 8/31/2010 Pharmacist United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Sinusitis Other Serious 3/1/2010 60 Female 160 lb 9/8/2010 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased Required Intervention 6/14/2010 53 Female 250 lb 8/27/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2008 47 Female 190 lb 9/14/2010 Other Health Professional United States
Primary
Concomitant
Dizziness 5/22/2010 52 Female 324 lb 9/14/2010 Consumer United States
Primary
Concomitant
Vomiting 3/1/2009 63 Female 170 lb 9/14/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 3/20/2009 71 Male 217 lb 9/16/2010 Consumer United States
Primary
Concomitant
Product Quality Issue 5/19/2009 74 Female 155 lb 9/17/2010 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2009 73 Female 180 lb 9/18/2010 Consumer United States
Primary
Concomitant
Incorrect Dose Administered Other Serious Female 9/17/2010 Physician United States
Primary
Concomitant
Mood Swings 52 Female 9/20/2010 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 12/19/2008 Female 9/20/2010 United States
Primary
Concomitant
Visual Impairment 52 Female 307 lb 9/20/2010 Consumer United States
Primary
Concomitant

Drug Data