Hydrochlorothiazide combined with Leucovorin Calcium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Life Threatening 5/30/2005 Male 235 lb 1/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumatosis Hospitalization 3/10/2005 Male 162 lb 1/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 59 Male 1/26/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Death Death 59 Male 345 lb 2/2/2006 Canada
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/14/2005 68 Male 150 lb 4/26/2006 Physician Australia
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/2/2006 Female 169 lb 5/3/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/2/2006 Female 169 lb 5/9/2006 Physician United States
Primary
Secondary
Concomitant
Perforated Ulcer Hospitalization 5/18/2006 Female 169 lb 5/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 59 Male 346 lb 5/20/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Vomiting Death 10/2/2005 76 Female 165 lb 6/5/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 65 Female 169 lb 6/12/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 4/28/2006 Female 169 lb 7/3/2006 Physician United States
Primary
Secondary
Concomitant
Pulse Absent Death 7/13/2006 Male 165 lb 7/13/2006 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2006 65 Female 7/19/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 5/1/2006 65 Female 7/20/2006 Physician United States
Primary
Secondary
Concomitant
Laryngospasm Other Serious 8/14/2006 76 Female 100 lb 8/30/2006 Pharmacist United States
Primary
Secondary
Concomitant
Abdominal Pain Lower Hospitalization 9/4/2006 70 Male 159 lb 10/11/2006 Physician Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 Male 159 lb 10/18/2006 United States
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/10/2005 Male 162 lb 11/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 5/26/2006 Female 167 lb 11/15/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/18/2006 64 Male 159 lb 11/20/2006 Physician United States
Primary
Secondary
Concomitant
Nerve Injury 7/15/2006 Female 180 lb 12/18/2006 Physician United States
Primary
Concomitant
Hypotension Death 12/31/2006 Male 99 lb 1/17/2007 Physician Venezuela
Primary
Secondary
Concomitant
Sepsis Life Threatening 1/24/2007 Female 112 lb 4/27/2007 Physician United States
Primary
Secondary
Concomitant
Female Genital Tract Fistula Other Serious 8/30/2005 Female 4/30/2007 Physician United States
Primary
Secondary
Concomitant
Prostate Cancer Other Serious Male 217 lb 6/11/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/10/2007 69 Female 187 lb 6/9/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism 1/11/2007 Male 174 lb 6/11/2007 United States
Primary
Secondary
Concomitant
Hypovolaemia 1/29/2007 Male 174 lb 6/13/2007 United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 11/22/2005 Male 6/15/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/1/2007 Female 6/19/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/24/2007 Female 112 lb 6/28/2007 Physician United States
Primary
Secondary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 7/12/2007 Lawyer United States
Primary
Concomitant
Ureteric Obstruction Other Serious 10/1/2004 Female 7/13/2007 Physician United States
Primary
Concomitant
Cerebral Ischaemia Hospitalization 7/1/2007 71 Male 8/16/2007 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 8/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumatosis Intestinalis Hospitalization 3/10/2005 Male 162 lb 9/6/2007 Other Health Professional United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/21/2007 Female 91 lb 9/7/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 8/21/2007 Female 91 lb 9/19/2007 Other Health Professional Brazil
Primary
Secondary
Concomitant
Sudden Death Death 8/25/2007 Male 166 lb 9/25/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Required Intervention Female 5/31/2007 Physician United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 11/15/2007 Male 159 lb 11/26/2007 United States
Primary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 11/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 8/14/2007 Female 165 lb 12/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 11/15/2007 Male 159 lb 12/10/2007 United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 12/17/2007 United States
Primary
Concomitant
Wound Drainage Other Serious 11/23/2001 52 Female 178 lb 1/7/2008 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/15/2008 68 Male 2/15/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 159 lb 2/21/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 3/4/2008 Female 125 lb 3/5/2008 United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 8/25/2007 Male 166 lb 3/21/2008 Consumer United States
Primary
Concomitant
White Blood Cells Urine Positive Hospitalization 6/1/2007 Female 3/24/2008 Physician United States
Primary
Concomitant
Septic Shock Other Serious 3/14/2007 78 Female 2/28/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2006 Male 4/29/2008 Physician United Kingdom
Primary
Secondary
Dehydration Hospitalization 6/14/2008 Female 73 lb 7/9/2008 South Africa
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/14/2008 Female 73 lb 8/1/2008 South Africa
Primary
Secondary
Concomitant
Sinus Tachycardia Death 10/2/2005 Female 165 lb 8/20/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 7/4/2008 Female 178 lb 8/22/2008 Physician United States
Primary
Concomitant
Oesophagitis Other Serious 5/27/2008 Female 124 lb 8/26/2008 Other Health Professional United States
Primary
Concomitant
Hypoventilation 6/20/2008 Female 106 lb 9/12/2008 Consumer United States
Primary
Concomitant
Tympanic Membrane Perforation Other Serious 63 Male 9/18/2008 Physician United States
Primary
Concomitant
Oesophagitis Other Serious 5/27/2008 Female 124 lb 9/25/2008 Other Health Professional United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 9/1/2008 Male 9/26/2008 Physician Germany
Primary
Secondary
Concomitant
Oesophagitis Other Serious 5/27/2008 Female 124 lb 10/9/2008 Other Health Professional United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/9/2009 Physician United States
Primary
Concomitant
Wound Drainage Other Serious 11/23/2001 Female 178 lb 2/13/2009 Lawyer United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 1/1/2008 Male 185 lb 2/20/2009 Physician United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 Male 159 lb 3/9/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection 10/25/2008 Female 3/14/2009 United States
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 9/1/2008 Male 243 lb 3/23/2009 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 9/1/2008 Male 243 lb 4/15/2009 Physician Germany
Primary
Secondary
Concomitant
Venous Thrombosis Hospitalization 9/1/2008 Male 243 lb 4/17/2009 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Death 8/23/2007 Female 91 lb 4/22/2009 Other Health Professional Brazil
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 3/1/2009 Female 128 lb 5/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Temperature Intolerance Other Serious 3/1/2009 Female 128 lb 5/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/16/2009 Male 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Hospitalization 4/1/2005 Female 5/22/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 18 Female 7/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 18 Female 7/24/2009 United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 2/12/2008 Female 8/13/2009 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 67 Female 150 lb 8/14/2009 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 8/10/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/13/2009 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 8/23/2009 Lawyer United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious Female 9/10/2009 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 68 Female 9/17/2009 United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 10/14/2007 Female 10/7/2009 Other Health Professional United States
Primary
Concomitant
Tremor Required Intervention 53 Male 11/3/2009 Physician Canada
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 11/7/2009 Male 114 lb 12/8/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Death 10/21/2009 69 Male 197 lb 1/6/2010 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/11/2010 71 Male 170 lb 2/22/2010 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2009 72 Male 5/14/2010 Consumer United States
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Death 6/26/2010 42 Female 7/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 5/12/2009 72 Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 9/10/2008 82 Male 150 lb 7/21/2010 Physician Spain
Primary
Secondary
Concomitant
Urethral Stenosis Other Serious 10/1/2004 61 Female 8/31/2010 Physician United States
Primary
Concomitant
Lymphopenia Other Serious 4/22/2010 68 Female 222 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Ureteric Operation Other Serious 10/1/2004 61 Female 170 lb 9/17/2010 Physician United States
Primary
Concomitant
Stomatitis Other Serious 2/1/2010 59 Male 157 lb 9/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/8/2010 70 Female 210 lb 11/23/2010 Physician Canada
Primary
Concomitant
Drug Ineffective 10/1/2010 76 Female 1/30/2011 Consumer United States
Primary
Concomitant
Febrile Neutropenia Death 4/26/2010 60 Male 163 lb 5/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Hospitalization 5/13/2011 67 Male 172 lb 6/1/2011 Physician Spain
Primary
Secondary
Concomitant
Clostridium Difficile Colitis Hospitalization 5/10/2011 49 Male 176 lb 6/1/2011 Physician United States
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 5/10/2011 49 Male 176 lb 6/6/2011 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/5/2005 77 Male 6/21/2011 Other Health Professional Austria
Primary
Secondary
Concomitant
Rectal Ulcer Hospitalization 5/10/2011 49 Male 176 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Sedimentation Rate Increased Other Serious 5/16/2011 66 Female 7/5/2011 Consumer United States
Primary
Concomitant
Ligament Injury Hospitalization 11/29/2006 47 Female 7/18/2011 Lawyer United States
Primary
Secondary
Concomitant
Bone Lesion Other Serious 11/29/2006 47 Female 7/29/2011 Physician United States
Primary
Secondary
Concomitant
Night Sweats Other Serious 11/29/2006 47 Female 160 lb 8/8/2011 Physician United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Hospitalization 5/19/2011 62 Female 152 lb 8/26/2011 Physician Czech Republic
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 10/24/2007 72 Male 159 lb 10/3/2011 Other Health Professional United States
Primary
Concomitant
Left Atrial Dilatation Other Serious 11/23/2001 52 Female 178 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Mental Disorder 11/25/2010 53 Female 135 lb 10/28/2011 Consumer United States
Primary
Secondary
Concomitant
Bronchitis 8/26/2011 57 Female 155 lb 11/6/2011 Consumer United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 11/29/2006 47 Female 160 lb 11/17/2011 Physician United States
Primary
Secondary
Concomitant
Angiopathy Other Serious 11/23/2001 52 Female 178 lb 12/8/2011 Lawyer United States
Primary
Secondary
Concomitant
Obesity Hospitalization 5/30/2008 50 Female 184 lb 12/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 11/29/2006 47 Female 160 lb 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Death 12/8/2011 75 Female 12/22/2011 Physician United States
Primary
Concomitant
Grand Mal Convulsion Death 12/8/2011 74 Female 12/27/2011 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Death 12/8/2011 74 Female 1/2/2012 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 11/29/2006 47 Female 160 lb 1/5/2012 Physician United States
Primary
Secondary
Concomitant
Radicular Cyst Death 12/1/2007 68 Male 1/6/2012 Physician United States
Primary
Concomitant
Lymphadenopathy Other Serious 12/1/2007 68 Male 1/9/2012 Physician United States
Primary
Concomitant
Sinus Tachycardia Other Serious Female 160 lb 1/4/2012 Lawyer United States
Primary
Concomitant
Staphylococcal Sepsis Death 12/1/2007 68 Male 1/13/2012 Physician United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/6/2009 64 Male 163 lb 1/11/2012 Physician United States
Primary
Secondary
Concomitant
Decreased Appetite Hospitalization 11/3/2009 64 Male 163 lb 1/18/2012 Physician United States
Primary
Secondary
Concomitant
Gout Hospitalization 12/1/2007 68 Male 1/24/2012 Physician United States
Primary
Concomitant
Enterocutaneous Fistula Hospitalization 11/15/2007 72 Male 159 lb 1/25/2012 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis 12/27/2010 66 Female 1/27/2012 Consumer United States
Primary
Concomitant
Cough 9/25/2011 62 Female 1/28/2012 Consumer United States
Primary
Concomitant
Pyrexia 10/1/2011 77 Female 148 lb 1/29/2012 Consumer United States
Primary
Secondary
Concomitant
Enterocutaneous Fistula Hospitalization 11/15/2007 72 Male 159 lb 1/31/2012 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 12/1/2007 68 Male 2/6/2012 Lawyer United States
Primary
Concomitant
Grand Mal Convulsion Death 12/8/2011 74 Female 209 lb 3/2/2012 Physician United States
Primary
Concomitant
Cellulitis Hospitalization 9/15/2011 68 Female 136 lb 2/27/2012 Physician United States
Primary
Concomitant
Fall Other Serious 12/1/2007 68 Male 3/8/2012 Physician United States
Primary
Concomitant
Balance Disorder Other Serious Female 148 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Prolonged Hospitalization 12/1/2007 68 Male 4/24/2012 Lawyer United States
Primary
Concomitant
Gaze Palsy 4/4/2007 60 Male 223 lb 5/18/2012 United States
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 5/9/2012 72 Female 5/31/2012 Physician Spain
Primary
Secondary
Concomitant
Cataract Other Serious Female 159 lb 6/14/2012 Other Health Professional Canada
Primary
Concomitant
Haematochezia Other Serious 2/1/2012 75 Male 170 lb 6/15/2012 Physician United States
Primary
Concomitant
Depression Life Threatening 7/19/2008 58 Male 6/21/2012 United States
Primary
Secondary
Concomitant
Rash Pruritic 3/1/2011 68 Female 185 lb 6/27/2012 Consumer United States
Primary
Secondary
Anaphylactic Reaction Death 12/8/2011 74 Female 209 lb 7/12/2012 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 7/20/2012 74 Male 7/27/2012 Physician Spain
Primary
Concomitant

Drug Data