Hydrochlorothiazide combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Radiation Oesophagitis Hospitalization 5/1/2005 Male 4/5/2006 Physician Germany
Primary
Concomitant
Staphylococcal Infection Hospitalization 2/1/2003 Female 178 lb 7/26/2006 Consumer United States
Primary
Concomitant
Radiation Oesophagitis Hospitalization 5/1/2005 Male 8/17/2006 Physician Germany
Primary
Concomitant
Ventricular Arrhythmia Life Threatening 2/22/2006 Female 9/21/2006 Physician Germany
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2005 Female 251 lb 10/26/2006 Consumer United States
Primary
Concomitant
Bordetella Infection Hospitalization 50 Male 11/28/2006
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/3/2006 Female 350 lb 1/17/2007 Consumer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/17/2005 Female 145 lb 2/7/2007 Physician Canada
Primary
Concomitant
Breast Mass Other Serious Female 148 lb 2/9/2007 Consumer Canada
Primary
Concomitant
Single Functional Kidney Other Serious 12/8/2005 Male 4/19/2007 Other Health Professional United States
Primary
Concomitant
Ulcer Other Serious 8/15/2006 Female 151 lb 5/3/2007 Consumer Canada
Primary
Concomitant
Ulcer Other Serious 4/1/2006 Female 151 lb 6/12/2007 Consumer Canada
Primary
Concomitant
Paraesthesia Hospitalization 6/21/2007 Female 141 lb 6/29/2007 Consumer Brazil
Primary
Concomitant
Tuberculosis Skin Test Positive Hospitalization 5/1/2006 Female 166 lb 9/14/2007 Physician United States
Primary
Concomitant
Transaminases Increased Hospitalization 7/1/2007 72 Female 10/9/2007 Spain
Primary
Concomitant
Contusion Other Serious 9/26/2007 Female 151 lb 11/7/2007 Canada
Primary
Concomitant
Contusion Other Serious 2/1/2007 Female 151 lb 11/19/2007 Canada
Primary
Concomitant
General Physical Health Deterioration Other Serious 4/1/2007 Female 161 lb 11/21/2007 Germany
Primary
Concomitant
General Physical Health Deterioration Other Serious 4/1/2007 Female 161 lb 11/26/2007 Germany
Primary
Concomitant
Injection Site Pain 1/1/2007 Female 168 lb 3/14/2008 Consumer United States
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 12/1/2007 Female 302 lb 3/15/2008 Physician United States
Primary
Concomitant
Paranasal Sinus Hypersecretion 2/2/2008 Female 140 lb 3/15/2008 United States
Primary
Concomitant
Increased Tendency To Bruise Other Serious 6/28/2006 Female 3/19/2008 Physician Finland
Primary
Concomitant
Psoriatic Arthropathy 8/1/2006 32 Male 154 lb 6/13/2008 Physician United States
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 6/30/2008 Germany
Primary
Secondary
Concomitant
Meniscus Lesion Other Serious 5/1/2008 Female 150 lb 7/8/2008 Consumer United States
Primary
Concomitant
Hyperplasia Hospitalization 8/21/2007 58 Female 7/11/2008 Germany
Primary
Secondary
Concomitant
Pain 10/1/2007 69 Female 7/7/2008 Consumer United States
Primary
Concomitant
Gastritis Hospitalization 6/21/2008 Female 159 lb 9/4/2008 Germany
Primary
Secondary
Concomitant
Psoriatic Arthropathy 8/1/2006 Male 154 lb 9/12/2008 Physician United States
Primary
Concomitant
Sneezing 3/19/2008 Female 123 lb 9/12/2008 United States
Primary
Concomitant
Pericarditis Other Serious 10/1/2007 Female 144 lb 9/12/2008 United States
Primary
Concomitant
Rash Papular 5/1/2008 Female 158 lb 9/12/2008 Pharmacist United States
Primary
Concomitant
Interacting
Sarcoidosis Other Serious 1/1/2006 Female 10/22/2008 Physician United States
Primary
Concomitant
Malignant Melanoma Other Serious 12/1/2007 Female 117 lb 11/25/2008 Physician United States
Primary
Concomitant
Wound Infection Bacterial 8/16/2006 Female 144 lb 12/9/2008 Physician United States
Primary
Concomitant
Injection Site Reaction 6/1/2008 Female 12/12/2008 Consumer United States
Primary
Concomitant
Subdural Haematoma Hospitalization Female 12/17/2008 Germany
Primary
Concomitant
Joint Injection Other Serious 11/21/2008 Female 158 lb 12/23/2008 Canada
Primary
Concomitant
Subdural Haematoma Hospitalization 7/26/2008 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Rash Papular 5/1/2008 Female 158 lb 3/13/2009 Pharmacist United States
Primary
Concomitant
Interacting
Ovarian Cyst Other Serious 12/6/2008 Female 4/9/2009 Brazil
Primary
Concomitant
Vomiting Hospitalization 2/28/2009 64 Male 4/15/2009 Consumer Colombia
Primary
Concomitant
Myocardial Infarction Hospitalization 4/9/2009 Male 4/23/2009 Consumer Brazil
Primary
Concomitant
Vomiting Hospitalization 2/28/2009 64 Male 5/4/2009 Consumer Colombia
Primary
Concomitant
Ventricular Extrasystoles Other Serious 53 Female 7/16/2009 Physician Italy
Primary
Concomitant
Hepatitis Acute Hospitalization 5/27/2009 64 Female 254 lb 8/13/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Exostosis Hospitalization 1/1/2009 46 Female 8/21/2009 Consumer Germany
Primary
Secondary
Concomitant
Incorrect Dose Administered 4/23/2007 Female 98 lb 9/11/2009 Consumer United States
Primary
Concomitant
Incorrect Dose Administered 8/15/2007 Female 127 lb 9/12/2009 Consumer United States
Primary
Concomitant
Tongue Ulceration Other Serious 6/5/2009 69 Female 132 lb 9/18/2009 Consumer United States
Primary
Concomitant
Oral Lichen Planus Other Serious 4/14/2008 Female 110 lb 10/5/2009 Physician Canada
Primary
Concomitant
Hepatitis Acute Hospitalization 5/27/2009 64 Female 254 lb 10/6/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 Female 220 lb 10/26/2009 Brazil
Primary
Concomitant
Hepatitis Acute Hospitalization 5/27/2009 64 Female 254 lb 10/27/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Urosepsis Hospitalization 8/25/2007 Female 10/27/2009 Germany
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2009 Female 198 lb 11/17/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting 10/2/2008 Female 11/23/2009 Consumer
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 9/28/2009 Female 198 lb 11/25/2009 Physician Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/28/2009 64 Male 12/1/2009 Consumer Colombia
Primary
Concomitant
Brain Neoplasm Malignant Other Serious 7/7/2009 Female 198 lb 12/18/2009 Brazil
Primary
Concomitant
Ovarian Cyst Other Serious 12/6/2008 Female 159 lb 12/23/2009 Brazil
Primary
Concomitant
Renal Disorder Hospitalization 1/15/2008 46 Male 331 lb 1/25/2010 Germany
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 12/18/2009 Female 154 lb 1/28/2010 Brazil
Primary
Concomitant
Anorectal Infection 10/1/2009 Male 285 lb 1/30/2010 United States
Primary
Concomitant
White Blood Cell Count Decreased 9/1/2009 Female 147 lb 1/30/2010 Consumer United States
Primary
Secondary
Concomitant
Acute Respiratory Failure Hospitalization 65 Male 223 lb 3/11/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 Female 225 lb 3/12/2010 Brazil
Primary
Concomitant
Hypoglycaemia Other Serious 12/18/2009 53 Female 154 lb 5/24/2010 Brazil
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 6/7/2010 Consumer Canada
Primary
Concomitant
Procedural Site Reaction Other Serious Female 143 lb 7/8/2010 Consumer Brazil
Primary
Concomitant
Pulmonary Mass Hospitalization 6/3/2010 55 Female 8/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/29/2010 55 Female 8/17/2010 Physician Thailand
Primary
Secondary
Concomitant
Paraesthesia 6/1/2010 56 Female 126 lb 7/26/2010 Consumer United States
Primary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 48 Female 225 lb 9/16/2010 Consumer Brazil
Primary
Concomitant
Pharyngeal Disorder 74 Female 10/13/2010 Consumer United States
Primary
Concomitant
Tooth Injury 64 Female 10/13/2010 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 141 lb 11/2/2010 Physician United Kingdom
Primary
Concomitant
Sudden Death Death 2/19/2010 67 Female 130 lb 11/19/2010 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 12/1/2010 Physician Canada
Primary
Concomitant
Myocardial Infarction Death 2/19/2010 67 Female 130 lb 12/1/2010 Physician Canada
Primary
Concomitant
Pollakiuria Other Serious 10/2/2010 57 Female 119 lb 12/6/2010 Consumer Brazil
Primary
Secondary
Concomitant
Upper Limb Fracture Other Serious 1/1/2007 48 Female 225 lb 12/15/2010 Consumer Brazil
Primary
Concomitant
Abdominal Pain 12/22/2010 Consumer United States
Primary
Concomitant
Nausea 2/1/2010 12/22/2010 Other Health Professional United States
Primary
Concomitant
Viith Nerve Paralysis Other Serious 5/19/2000 66 Female 10/28/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain 4/6/2010 62 Male 260 lb 1/28/2011 United States
Primary
Concomitant
Injection Site Pain 6/25/2010 46 Male 1/29/2011 Consumer United States
Primary
Concomitant
Fatigue 1/1/2005 46 Female 260 lb 1/30/2011 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 8/9/2010 61 Female 1/30/2011 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 12/1/2009 60 Female 153 lb 1/30/2011 Physician United States
Primary
Concomitant
Influenza Hospitalization 1/1/2007 47 Female 157 lb 3/16/2011 Consumer Brazil
Primary
Concomitant
Pain In Extremity Other Serious 11/1/2010 53 Female 161 lb 4/15/2011 Consumer Brazil
Primary
Concomitant
Arthritis 9/1/2009 Female 180 lb 5/13/2011 Consumer United States
Primary
Concomitant
Alopecia Other Serious 11/1/2010 66 Female 88 lb 5/17/2011 Consumer Mexico
Primary
Concomitant
Foot Fracture Other Serious 10/2/2010 57 Female 119 lb 5/24/2011 Consumer Brazil
Primary
Secondary
Concomitant
Foot Deformity Other Serious 10/2/2010 57 Female 119 lb 5/25/2011 Consumer Brazil
Primary
Secondary
Concomitant
Poor Quality Sleep Hospitalization 11/22/2010 68 Female 176 lb 5/26/2011 Consumer Netherlands
Primary
Concomitant
Foot Deformity Other Serious 10/2/2010 57 Female 119 lb 5/26/2011 Consumer Brazil
Primary
Secondary
Concomitant
Joint Injury Other Serious 7/1/2003 42 Female 200 lb 6/9/2011 Consumer United States
Primary
Concomitant
Influenza Other Serious 3/23/2011 58 Female 186 lb 6/9/2011 Pharmacist Canada
Primary
Concomitant
Paraesthesia Male 220 lb 8/6/2011 Consumer United States
Primary
Concomitant
Osteoarthritis Hospitalization 2/12/2011 58 Female 178 lb 9/21/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 1/1/2002 66 Female 122 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Foot Fracture Other Serious 10/2/2010 57 Female 121 lb 9/27/2011 Consumer Brazil
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 10/1/2010 54 Female 140 lb 10/19/2011 Physician Canada
Primary
Concomitant
Chills 10/29/2010 Female 10/27/2011 United States
Primary
Concomitant
Dental Caries 64 Female 10/24/2011 Lawyer United States
Primary
Concomitant
Septic Shock Death 9/12/2010 62 Female 176 lb 10/28/2011 Consumer Brazil
Primary
Concomitant
Osteoarthritis Other Serious 9/30/2011 59 Female 178 lb 11/3/2011 Consumer Canada
Primary
Concomitant
Osteoarthritis Other Serious 9/30/2011 59 Female 178 lb 11/29/2011 Physician Canada
Primary
Concomitant
Arthralgia Other Serious 11/1/2010 53 Female 161 lb 12/14/2011 Consumer Brazil
Primary
Concomitant
Fall Other Serious 1/1/2007 47 Female 157 lb 12/22/2011 Consumer Brazil
Primary
Concomitant
Arthralgia Hospitalization 1/1/2007 47 Female 157 lb 12/27/2011 Consumer Brazil
Primary
Concomitant
Foetal Exposure During Pregnancy Congenital Anomaly 12/28/2011 Physician United States
Primary
Concomitant
Arthralgia Hospitalization 1/17/2012 40 Male 200 lb 1/26/2012 Pharmacist Canada
Primary
Concomitant
Hepatic Cyst 1/1/2011 63 Female 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Haemorrhage 8/6/2011 54 Female 1/28/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection 4/1/2011 58 Female 200 lb 1/28/2012 Consumer United States
Primary
Concomitant
Fall Other Serious 6/1/2011 63 Female 119 lb 1/28/2012 Physician United States
Primary
Concomitant
Injection Site Nodule 2/1/2011 63 Female 138 lb 1/28/2012 Consumer United States
Primary
Concomitant
Drug Effect Decreased 1/1/2011 42 Male 324 lb 1/29/2012 Consumer United States
Primary
Concomitant
Headache 4/1/2008 54 Female 1/29/2012 Consumer United States
Primary
Concomitant
Injection Site Pain 9/30/2011 58 Female 1/28/2012 Consumer United States
Primary
Concomitant
Osteoarthritis Other Serious 9/30/2011 59 Female 178 lb 2/6/2012 Physician Canada
Primary
Concomitant
Headache Hospitalization 2/12/2011 58 Female 178 lb 2/7/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Rash Pruritic Other Serious 2/12/2011 58 Female 178 lb 2/7/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 1/22/2012 80 Male 151 lb 2/9/2012 Other Health Professional Canada
Primary
Concomitant
Asthenia 3/10/2011 56 Female 2/10/2012 Consumer United States
Primary
Concomitant
Wheezing Other Serious 7/1/2011 48 Male 160 lb 2/27/2012 Consumer United States
Primary
Concomitant
Cough Other Serious 7/1/2011 48 Male 160 lb 3/2/2012 Consumer United States
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 3/1/2011 56 Female 174 lb 3/20/2012 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 10/20/2011 54 Female 154 lb 3/22/2012 Physician Germany
Primary
Secondary
Concomitant
Asthenia Other Serious Male 165 lb 3/22/2012 Other Health Professional Canada
Primary
Concomitant
Intervertebral Disc Protrusion Hospitalization 11/10/2011 57 Female 174 lb 4/13/2012 Physician Germany
Primary
Secondary
Concomitant
Spinal Pain Other Serious 1/1/2011 72 Female 5/7/2012 Consumer Colombia
Primary
Concomitant
Pain 7/1/2003 42 Female 200 lb 5/17/2012 Consumer United States
Primary
Concomitant
Impaired Healing Hospitalization 8/23/2010 61 Female 5/23/2012 Physician Germany
Primary
Secondary
Concomitant
Back Pain Other Serious 4/1/2002 55 Female 121 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Inflammation Other Serious 1/1/2011 72 Female 5/25/2012 Consumer Colombia
Primary
Concomitant
Pruritus 12/1/2011 68 Female 5/24/2012 Consumer United States
Primary
Concomitant
Joint Injury 7/1/2003 50 Female 200 lb 5/31/2012 Consumer United States
Primary
Concomitant
Rash 5/1/2012 66 Male 6/5/2012 Other Health Professional United States
Primary
Concomitant
Hypertension Hospitalization 10/27/2011 52 Female 154 lb 6/5/2012 Physician Germany
Primary
Secondary
Concomitant
Retching Other Serious 5/28/2012 60 Female 143 lb 6/27/2012 Consumer Brazil
Primary
Secondary
Concomitant
Pain In Jaw Hospitalization 11/22/2010 68 Female 176 lb 6/29/2012 Consumer Netherlands
Primary
Concomitant
Blood Creatine Phosphokinase Increased Other Serious 6/1/2012 66 Male 403 lb 7/26/2012 Physician Germany
Primary
Concomitant
Rotator Cuff Syndrome Hospitalization 5/8/2011 Female 8/1/2012 Physician Germany
Primary
Secondary
Concomitant
Dizziness Other Serious 2/1/2011 66 Female 7/21/2011 Consumer United States
Primary
Secondary
Concomitant
Rotator Cuff Syndrome Hospitalization 5/8/2011 71 Female 225 lb 8/21/2012 Physician Germany
Primary
Secondary
Concomitant

Drug Data