Hydrochlorothiazide combined with Isosorbide Mononitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Muscle Disorder Hospitalization 12/25/2005 71 Male 1/11/2006 Consumer United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Hospitalization 11/11/1999 80 Female 150 lb 1/17/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Male 1/17/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/25/2001 88 Female 157 lb 1/26/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 51 Male 1/31/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 Male 1/30/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2005 51 Male 2/2/2006 United States
Primary
Secondary
Concomitant
Ischaemic Stroke Hospitalization 5/9/2005 77 Male 220 lb 2/21/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 5/9/2005 77 Male 220 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Skin Cancer Life Threatening 5/9/2005 77 Male 220 lb 3/10/2006 Poland
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Myalgia Other Serious 7/22/2005 51 Male 227 lb 4/13/2006 Pharmacist United States
Primary
Concomitant
Oedema Peripheral Other Serious 12/8/2003 66 Female 181 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Overdose Other Serious 11/1/2005 35 Male 4/17/2006 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 11/11/1999 80 Female 150 lb 4/21/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/22/2005 45 Female 150 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2000 65 Male 256 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Hyponatraemia Hospitalization 2/25/2005 78 Female 176 lb 5/25/2006 Physician Finland
Primary
Concomitant
Macular Oedema 10/1/2005 74 Male 5/19/2006 Physician United States
Primary
Concomitant
Pneumonia 3/1/2006 54 Female 5/23/2006 Consumer United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/21/2006 64 Male 224 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 42 Female 174 lb 9/8/2006 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 6/20/2006 Male 9/11/2006 Pharmacist United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 1/1/2000 42 Female 174 lb 9/29/2006 Consumer United States
Primary
Concomitant
Acute Generalised Exanthematous Pustulosis Hospitalization 91 12/6/2006 Physician Israel
Primary
Secondary
Concomitant
Visual Disturbance Hospitalization Female 1/4/2007 Consumer United States
Primary
Concomitant
Presyncope Hospitalization 9/8/2006 Male 209 lb 11/4/2006 Pharmacist United States
Primary
Concomitant
Disturbance In Attention Other Serious 4/1/2007 Female 130 lb 5/9/2007 Consumer United States
Primary
Concomitant
Hallucination Hospitalization 1/2/2007 60 Male 5/9/2007 Pharmacist United States
Primary
Concomitant
Suicidal Ideation 10/27/2006 41 Male 2/28/2007 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 10/1/2006 77 Female 134 lb 4/30/2007 Pharmacist United States
Primary
Concomitant
Drug Administration Error Other Serious 4/1/2007 Female 130 lb 6/11/2007 Physician United States
Primary
Concomitant
Blood Disorder 1/11/2007 Male 170 lb 7/26/2007 Consumer United States
Primary
Concomitant
Muscle Spasticity Other Serious 1/1/2007 Female 177 lb 9/10/2007 United States
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 7/1/2006 66 Female 162 lb 9/12/2007 Physician United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/25/2007 65 Female 167 lb 11/7/2007 Physician Hungary
Primary
Secondary
Concomitant
Vertigo Hospitalization 10/25/2007 65 Female 167 lb 11/29/2007 Physician Hungary
Primary
Secondary
Concomitant
Pain In Extremity 75 Male 11/16/2007 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 12/6/2007 66 Female 151 lb 12/18/2007 Physician Hungary
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 8/1/2002 68 Male 201 lb 2/1/2008 United States
Primary
Concomitant
Mental Status Changes Required Intervention 2/17/2008 80 Female 141 lb 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pharyngolaryngeal Pain 4/18/2008 Female 140 lb 6/13/2008 United States
Primary
Concomitant
Insomnia 5/1/2008 74 Female 5/21/2008 Other Health Professional United States
Primary
Concomitant
Headache 7/7/2008 Female 8/27/2008 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 5/7/2008 Female 9/11/2008 Other Health Professional Portugal
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 5/7/2008 Female 9/24/2008 Other Health Professional Portugal
Primary
Secondary
Concomitant
Syncope Hospitalization 1/1/2008 85 Female 10/7/2008 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 4/4/2005 Male 225 lb 10/17/2008 Lawyer United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/17/2008 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 4/4/2005 Male 225 lb 10/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Lethargy Other Serious 4/18/2005 Male 10/24/2008 Consumer United States
Primary
Concomitant
Medication Residue Female 11/17/2008 Physician Puerto Rico
Primary
Concomitant
Angina Pectoris Hospitalization 10/10/2008 Male 11/20/2008 Canada
Primary
Concomitant
Sneezing 10/1/2008 Male 245 lb 11/26/2008 Pharmacist United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2008 63 Male 12/9/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Death 11/21/2008 86 Male 180 lb 12/15/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 10/27/2008 59 Male 165 lb 12/17/2008 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 1/1/2006 38 Female 140 lb 12/17/2008 Consumer United States
Primary
Concomitant
Stent Placement Hospitalization 4/1/2008 49 Female 255 lb 1/21/2009 Consumer United States
Primary
Concomitant
Hypertension Death 71 Male 1/21/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Hospitalization 3/19/2008 75 Male 1/23/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Death 9/11/2008 67 Male 2/23/2009 Consumer United States
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Life Threatening 3/6/2008 77 Male 176 lb 3/5/2009 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 3/6/2008 77 Male 176 lb 3/6/2009 Pharmacist Germany
Primary
Secondary
Concomitant
Medication Residue Male 3/12/2009 Pharmacist United States
Primary
Concomitant
Anaemia Hospitalization 10/25/2007 Female 167 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Anaemia Hospitalization 12/6/2007 Female 151 lb 3/30/2009 Physician Hungary
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2005 69 Male 12/4/2008 United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 3/27/2009 Male 4/29/2009 Physician United States
Primary
Concomitant
Swelling Face 1/1/2007 5/4/2009 United States
Primary
Concomitant
Swelling Face 1/1/2007 Female 120 lb 5/22/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/22/2000 45 Male 266 lb 7/10/2009 United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/1/2009 Male 173 lb 7/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting 68 Male 8/4/2009 Consumer United States
Primary
Concomitant
Road Traffic Accident Other Serious 5/1/2009 Male 173 lb 8/25/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal 5/12/2009 Male 220 lb 8/29/2009 Consumer United States
Primary
Concomitant
Muscle Rupture Hospitalization 69 Male 10/8/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Muscle Rupture Hospitalization 69 Male 11/16/2009 Other Health Professional Netherlands
Primary
Concomitant
Interacting
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 1/20/2010 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 11/17/2008 69 Male 263 lb 1/20/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 Male 3/4/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 10/14/2008 77 Female 3/3/2010 Consumer United States
Primary
Concomitant
Wheezing Hospitalization 11/27/2006 76 Female 145 lb 3/3/2010 Lawyer United States
Primary
Concomitant
Syncope Hospitalization 11/17/2008 69 Male 263 lb 3/3/2010 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/24/2007 Female 4/22/2010 United States
Primary
Concomitant
Renal Cyst Hospitalization 7/31/2008 70 Male 164 lb 5/5/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 5/13/2010 Physician United States
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/3/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 6/3/2010 Other Health Professional United States
Primary
Concomitant
Paraesthesia Other Serious 1/1/2008 54 Female 179 lb 6/16/2010 Lawyer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 4/5/2010 11 Female 6/18/2010 Pharmacist Netherlands
Primary
Secondary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 6/24/2010 Physician United States
Primary
Secondary
Concomitant
Flatulence 2/1/2007 66 Male 148 lb 7/9/2010 Consumer United States
Primary
Concomitant
Nausea 2/21/2007 65 Female 168 lb 7/12/2010 Other Health Professional United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Skin Discolouration Other Serious 1/1/2008 51 Male 247 lb 7/27/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 11/1/2008 8/3/2010 Other Health Professional Algeria
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/4/2010 Physician United States
Primary
Concomitant
Paraesthesia Other Serious 7/1/2008 54 Female 179 lb 8/12/2010 Physician United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 8/31/2010 Physician United States
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 3/18/2007 77 Female 214 lb 8/25/2010 Physician United States
Primary
Concomitant
Pancreatic Neoplasm Hospitalization 7/31/2008 70 Male 164 lb 9/2/2010 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 8/13/2010 60 Male 225 lb 9/9/2010 Physician United States
Primary
Secondary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 9/21/2010 Physician United States
Primary
Secondary
Concomitant
Skin Discolouration Other Serious 1/1/2008 51 Male 247 lb 9/22/2010 Other Health Professional United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 9/30/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 10/6/2010 Physician United States
Primary
Concomitant
Anxiety 9/28/2010 65 Male 160 lb 10/7/2010 Consumer United States
Primary
Concomitant
Pharyngeal Oedema Other Serious Female 10/19/2010 United States
Primary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 10/21/2010 Physician United States
Primary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 10/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 11/1/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Thrombosis Other Serious 12/1/2007 54 Male 163 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Vertigo Other Serious 9/28/2010 65 Male 160 lb 11/3/2010 Consumer United States
Primary
Concomitant
Treatment Noncompliance Other Serious 9/1/2010 56 Male 212 lb 11/12/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 3/6/2008 77 Male 176 lb 11/16/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Wound Infection Other Serious 10/1/2010 65 Male 220 lb 11/29/2010 Consumer United States
Primary
Concomitant
Myalgia Female 12/16/2010 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 12/21/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Headache Other Serious 7/1/2008 54 Female 179 lb 2/3/2011 Physician United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Eye Pruritus Other Serious 12/4/2008 67 Male 254 lb 2/17/2011 Other Health Professional United States
Primary
Concomitant
Proteus Infection Hospitalization 7/31/2008 70 Male 164 lb 2/25/2011 Physician United States
Primary
Concomitant
Pruritus Hospitalization 8/13/2010 60 Male 225 lb 3/4/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Disorder Hospitalization 64 Female 193 lb 3/11/2011 Physician United States
Primary
Concomitant
Hot Flush 3/1/2011 61 Female 107 lb 3/31/2011 Consumer United States
Primary
Secondary
Concomitant
Abnormal Dreams 3/1/2011 61 Female 107 lb 4/5/2011 Consumer United States
Primary
Secondary
Concomitant
Fall 2/1/2011 88 Female 4/12/2011 Consumer United States
Primary
Concomitant
Muscle Spasms Hospitalization 1/29/2011 45 Female 175 lb 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Arrhythmia Other Serious 12/1/2007 54 Male 163 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Disorder 3/1/2011 61 Female 107 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Oedema Hospitalization Male 220 lb 4/29/2011 Consumer Brazil
Primary
Secondary
Concomitant
Pollakiuria Hospitalization 10/14/2008 77 Female 4/29/2011 Consumer United States
Primary
Concomitant
Dystonia Other Serious 7/1/2009 58 Female 175 lb 5/23/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 4/21/2004 75 Female 225 lb 6/25/2011 Other Health Professional United States
Primary
Concomitant
Mobility Decreased Other Serious 12/1/2006 79 Male 187 lb 7/14/2011 Lawyer United States
Primary
Concomitant
Angina Pectoris Hospitalization 4/1/2007 64 Female 193 lb 7/19/2011 Lawyer United States
Primary
Concomitant
Diabetic Vascular Disorder Other Serious 6/2/2004 68 Female 287 lb 7/12/2011 Physician United States
Primary
Concomitant
Thrombocytopenia Death 12/1/2007 54 Male 163 lb 7/22/2011 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Output Decreased Other Serious 12/1/2007 54 Male 163 lb 7/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Upper 83 Female 7/25/2011 Consumer United States
Primary
Concomitant
Application Site Pruritus 5/2/2011 83 Female 150 lb 7/25/2011 Consumer United States
Primary
Concomitant
Injection Site Reaction Hospitalization 1/1/2007 71 Male 225 lb 7/29/2011 Physician Hungary
Primary
Secondary
Concomitant
International Normalised Ratio Increased Death 79 Male 8/11/2011 Physician United States
Primary
Concomitant
Acute Myocardial Infarction Other Serious 8/17/2011 Other Health Professional United States
Primary
Concomitant

Drug Data