Hydrochlorothiazide combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Disorder Hospitalization 9/4/2004 87 Male 161 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Bladder Disorder Hospitalization 2/13/2006 Female 140 lb 2/24/2006 Consumer Canada
Primary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 12/27/2003 87 Male 161 lb 3/23/2006 Physician United States
Primary
Concomitant
Pancytopenia Other Serious 3/7/2003 Female 126 lb 4/3/2006 Other Health Professional Poland
Primary
Secondary
Concomitant
Hypoglycaemia Required Intervention 6/27/2005 77 Male 155 lb 5/24/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/1/2006 64 Female 265 lb 6/28/2006 Physician Germany
Primary
Concomitant
Rhabdomyolysis Life Threatening 3/1/2006 64 Female 265 lb 6/28/2006 Physician Germany
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/24/2006 67 Male 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Gastrooesophageal Reflux Disease 3/1/2006 61 Female 4/17/2006 Other Health Professional United States
Primary
Concomitant
Hypoglycaemic Seizure Hospitalization 12/28/2005 71 Female 5/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Bradycardia Hospitalization 6/5/2006 71 Male Pharmacist United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 8/4/2006 Physician United States
Primary
Concomitant
Wheezing Hospitalization 2/23/2006 67 Male 188 lb 8/17/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 6/21/2006 70 Male 189 lb 7/17/2006 Pharmacist United States
Primary
Concomitant
Throat Tightness Hospitalization 1/1/2006 57 Female 213 lb 8/30/2006 Physician United States
Primary
Concomitant
Heart Rate Increased 6/1/2005 38 Female 406 lb 11/13/2006 Consumer United States
Primary
Concomitant
Skin Cancer Other Serious 72 Male 250 lb 1/8/2007 Consumer United States
Primary
Concomitant
Neurological Symptom Other Serious 72 Male 250 lb 1/9/2007 Consumer United States
Primary
Concomitant
Shock Other Serious 9/15/2006 Male 172 lb 2/6/2007 Physician Germany
Primary
Concomitant
Nightmare Hospitalization 84 Male 200 lb 8/21/2004 Other Health Professional United States
Primary
Secondary
Angioedema Disability 1/1/2007 47 Male 3/28/2007 Pharmacist United States
Primary
Concomitant
Haemorrhoidal Haemorrhage Other Serious 60 Male 170 lb 12/13/2006 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/15/2007 78 Female 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 78 Female 121 lb 6/1/2007 Other Health Professional United States
Primary
Secondary
Tremor Hospitalization 5/26/2007 81 Male 240 lb 6/5/2007 Pharmacist United States
Primary
Concomitant
Cholelithiasis Hospitalization 2/22/2007 78 Female 122 lb 6/12/2007 United States
Primary
Secondary
Cholelithiasis Hospitalization 2/22/2007 78 Female 122 lb 6/18/2007 United States
Primary
Concomitant
Toothache Other Serious 12/30/2006 Female 180 lb 6/22/2007 Consumer United States
Primary
Concomitant
Vision Blurred 11/15/2006 Female 232 lb 6/26/2007 Physician United States
Primary
Concomitant
Tremor Other Serious 3/1/2007 64 Male 263 lb 4/26/2007 United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Intraocular Pressure Increased Other Serious Female 140 lb 6/29/2007 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/13/2007 United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 5/1/2007 8/10/2007 Consumer United States
Primary
Concomitant
Lethargy 9/22/2006 Female 150 lb 5/1/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Required Intervention 4/15/2007 50 Male 220 lb 4/26/2007 Pharmacist United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2006 Female 8/27/2007 Consumer United States
Primary
Concomitant
Bundle Branch Block Right Hospitalization 4/8/2006 Male 9/13/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/11/2007 89 Male 9/26/2007 Consumer Brazil
Primary
Secondary
Concomitant
Muscular Weakness 3/1/2006 76 Female 10/25/2007 Consumer United States
Primary
Concomitant
Nocturnal Dyspnoea 8/22/2007 69 Male 11/14/2007 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 8/29/2007 Female 160 lb 11/16/2007 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain 73 Male 11/16/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 9/17/2007 61 269 lb 11/30/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 9/12/2007 Female 175 lb 12/14/2007 Physician United States
Primary
Concomitant
Uveitis Other Serious 11/16/2007 Female 12/17/2007 Physician United Kingdom
Primary
Concomitant
Lung Disorder Other Serious 9/1/2007 Male 235 lb 12/18/2007 Other Health Professional United States
Primary
Concomitant
Thrombotic Stroke Hospitalization 11/29/2007 Male 230 lb 12/18/2007 Consumer United States
Primary
Concomitant
Pollakiuria Male 12/20/2007 Consumer United States
Primary
Concomitant
Dysphagia 8/1/2007 84 Male 12/20/2007 Consumer United States
Primary
Concomitant
Back Pain 9/1/2007 83 Male 225 lb 10/5/2007 Consumer United States
Primary
Concomitant
Application Site Rash 1/1/2006 64 Female 146 lb 11/27/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 3/16/2008 Female 132 lb 3/31/2008 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/27/2008 Female 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Unevaluable Event Hospitalization 3/1/2007 Male 170 lb 4/25/2008 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/1/2007 Male 170 lb 5/1/2008 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/1/2007 Male 172 lb 5/7/2008 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1969 Female 5/23/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 Female 185 lb 6/2/2008 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 12/15/2006 60 Male 265 lb 4/30/2008 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 86 Female 6/20/2008 Physician United States
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Hyperglycaemia Other Serious 7/20/2007 52 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 8/21/2008 Physician Germany
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 80 Female 8/19/2008 Canada
Primary
Secondary
Concomitant
Pruritus Generalised 12/6/2007 Male 219 lb 8/27/2008 Consumer United States
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/27/2008 United States
Primary
Concomitant
Back Pain Other Serious 7/5/2008 10/13/2008 Canada
Primary
Concomitant
Nausea Hospitalization 11/7/2008 55 Female 200 lb 12/4/2008 Consumer United States
Primary
Concomitant
Dizziness Hospitalization 5/24/2008 75 Male 1/21/2009 Consumer Germany
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 12/25/2004 75 Female 155 lb 1/23/2009 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 84 Female 1/24/2009 United States
Primary
Concomitant
Vision Blurred Hospitalization 84 Female 2/27/2009 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 12/25/2004 75 Female 155 lb 3/12/2009 Consumer United States
Primary
Concomitant
Alopecia 5/1/2007 Female 198 lb 3/12/2009 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Other Serious 77 Female 4/13/2009 Canada
Primary
Concomitant
Vision Blurred Hospitalization 84 Female 4/22/2009 United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 5/29/2009 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 5/5/2006 59 Male 257 lb 6/2/2009 United States
Primary
Concomitant
Nausea Other Serious 3/26/2009 Female 238 lb 6/9/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Other Serious 5/2/2003 Male 6/25/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatic Necrosis Death 62 Female 7/17/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 1/1/2007 84 Female 7/15/2009 United States
Primary
Concomitant
Vomiting Death 86 Female 7/20/2009 United States
Primary
Concomitant
Flushing 6/1/2008 Male 223 lb 8/21/2009 United States
Primary
Concomitant
Vision Blurred 8/20/2008 Male 8/21/2009 United States
Primary
Concomitant
Platelet Count Decreased Male 173 lb 8/22/2009 Physician United States
Primary
Concomitant
Hypotension Hospitalization 8/10/2009 Male 8/26/2009 Physician Switzerland
Primary
Secondary
Concomitant
Hypotension Hospitalization 8/10/2009 Male 9/2/2009 Physician Switzerland
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 8/1/2009 66 10/2/2009 Consumer Brazil
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 8/1/2009 66 10/13/2009 Consumer Brazil
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 8/1/2009 66 10/16/2009 Consumer Brazil
Primary
Secondary
Concomitant
Poor Quality Drug Administered Other Serious 8/1/2009 66 10/29/2009 Consumer Brazil
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 9/20/2009 Male 300 lb 10/20/2009 Consumer United States
Primary
Concomitant
Hyperkalaemia Hospitalization 11/30/2007 Male 198 lb 11/30/2009 Physician Germany
Primary
Secondary
Concomitant
Tenodesis Hospitalization 64 Female 3/5/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/26/2010 Physician Argentina
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 Female 3/29/2010 Physician Argentina
Primary
Concomitant
Low Density Lipoprotein Increased Other Serious 1/1/2010 Female 172 lb 3/31/2010 United States
Primary
Concomitant
Middle Insomnia 3/11/2010 69 Male 4/7/2010 Consumer
Primary
Concomitant
Vomiting Life Threatening 2/11/2010 81 Female 4/9/2010 Physician Argentina
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/3/2010 55 Female 4/23/2010 Other Health Professional United States
Primary
Concomitant
Syncope Hospitalization 5/26/2008 66 Male 234 lb 4/27/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Syncope Hospitalization 5/26/2008 66 Male 234 lb 5/4/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Syncope Hospitalization 5/26/2008 66 Male 234 lb 5/6/2010 Pharmacist Germany
Primary
Secondary
Concomitant
Interacting
Therapeutic Response Decreased Life Threatening 5/26/2008 66 Male 5/10/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/19/2009 79 Male 141 lb 6/2/2010 United States
Primary
Secondary
Concomitant
Renal Neoplasm Other Serious 2/1/2010 Female 7/8/2010 Consumer Germany
Primary
Concomitant
Vomiting 1/3/2007 60 Female 280 lb 7/9/2010 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 75 Male 7/22/2010 Consumer Germany
Primary
Concomitant
Suicide Attempt Other Serious 3/25/2008 46 Male 7/23/2010 Lawyer United States
Primary
Concomitant
Renal Neoplasm Other Serious 1/1/2010 Female 7/29/2010 Physician Germany
Primary
Concomitant
Intraocular Pressure Increased Other Serious 4/22/2010 76 Female 8/3/2010 Physician Germany
Primary
Concomitant
Intraocular Pressure Increased Other Serious 4/22/2010 76 Female 8/6/2010 Physician Switzerland
Primary
Concomitant
Weight Decreased Other Serious 49 Male 8/10/2010 United States
Primary
Concomitant
Incorrect Drug Administration Duration Male 10/13/2010 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 55 Male 215 lb 10/20/2010 United States
Primary
Concomitant
Oral Mucosal Exfoliation Female 11/2/2010 United States
Primary
Concomitant
Vomiting 3/1/2010 54 Male 229 lb 11/4/2010 Consumer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 12/12/2008 Female 138 lb 11/3/2010 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/13/2010 72 Female 11/8/2010 Physician Germany
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2010 55 Female 295 lb 11/16/2010 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 9/11/2010 55 Female 295 lb 11/22/2010 Physician United States
Primary
Concomitant
Penile Haemorrhage Other Serious 11/1/2010 83 Male 158 lb 11/23/2010 Consumer United States
Primary
Concomitant
Migraine 1/1/2008 63 Female 11/29/2010 Consumer
Primary
Concomitant
Nasopharyngitis 1/1/2008 50 Female 12/29/2010 Consumer United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 12/29/2010 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 9/1/2010 56 Male 212 lb 1/4/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/5/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Lip Swelling 12/1/2010 81 Male 1/10/2011 Consumer
Primary
Concomitant
Cardiac Tamponade Life Threatening 9/7/2010 55 Female 295 lb 1/12/2011 Physician United States
Primary
Concomitant
Peripheral Arterial Occlusive Disease Other Serious 72 Female 1/13/2011 Consumer United States
Primary
Concomitant
Cholecystitis Other Serious 7/5/2006 36 Female 160 lb 1/14/2011 Consumer United States
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 7/5/2006 36 Female 160 lb 1/14/2011 Physician United States
Primary
Secondary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 1/24/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/1/2010 56 Male 212 lb 1/25/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Cerebrovascular Accident Hospitalization 50 Male 211 lb 2/4/2011 Pharmacist United States
Primary
Concomitant
Jaundice Cholestatic Other Serious 9/1/2010 56 Male 212 lb 2/7/2011 Physician Russian Federation
Primary
Secondary
Concomitant
Activities Of Daily Living Impaired Hospitalization Female 3/16/2011 United States
Primary
Concomitant
Injury Hospitalization 10/2/2005 52 Female 220 lb 3/23/2011 Physician United States
Primary
Concomitant
Anhedonia Other Serious 10/2/2005 52 Female 220 lb 3/23/2011 Lawyer United States
Primary
Concomitant
Laryngeal Cancer Stage Iv Hospitalization 8/1/2003 70 Male 3/29/2011 Consumer United States
Primary
Secondary
Concomitant
Dysgeusia 2/2/2011 69 Male 4/14/2011 Pharmacist United States
Primary
Concomitant
Pain Hospitalization 86 Male 4/15/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 6/28/2005 69 Female 198 lb 4/18/2011 Other Health Professional United States
Primary
Concomitant
Sluggishness Hospitalization 1/15/2011 89 Female 4/19/2011 Consumer United States
Primary
Concomitant
Cardiac Disorder Hospitalization 4/1/2006 48 Male 239 lb 4/21/2011 Consumer United States
Primary
Concomitant

Drug Data