Hydralazine combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Treatment Noncompliance 9/23/2005 Male 9/26/2005 United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2005 62 Female 205 lb 1/27/2006 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 9/4/2004 87 Male 161 lb 2/16/2006 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 10/14/2005 75 Male 210 lb 1/17/2006 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 11/14/2005 75 Male 215 lb 2/7/2006 Other Health Professional United States
Primary
Concomitant
International Normalised Ratio Increased 11/13/2005 74 Male 12/8/2005 Pharmacist United States
Primary
Concomitant
Retinal Haemorrhage Other Serious 1/9/2004 74 Female 140 lb 12/29/2005 Consumer United States
Primary
Concomitant
Hyperkalaemia Required Intervention 3/6/2006 79 Male 184 lb 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 6/29/2005 49 Male 170 lb 3/17/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 12/27/2003 87 Male 161 lb 3/23/2006 Physician United States
Primary
Concomitant
Scrotal Swelling Hospitalization 3/14/2006 50 Male 225 lb 3/23/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dyskinesia Hospitalization 9/1/2001 71 Male 276 lb 3/28/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 61 Female 3/29/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 7/4/2005 76 Female 190 lb 3/29/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased 10/20/2005 74 Female 190 lb 1/20/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 9/1/2001 71 Male 276 lb 5/4/2006 Physician United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 8/28/2007 50 Male 10/4/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Mitral Valve Incompetence Hospitalization 11/1/2007 77 Male 207 lb 12/24/2007 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 1/1/2004 84 Female 143 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Other Serious 12/1/2008 63 Male 7/9/2009 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization Female 9/16/2009 United States
Primary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/19/2009 Male 9/24/2009 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Death 3/18/2009 Female 9/23/2009 Pharmacist United States
Primary
Concomitant
Somnolence 5/28/2009 74 Female 190 lb 6/15/2009 Pharmacist United States
Primary
Concomitant
Oesophagitis Required Intervention 5/21/2009 63 Male 181 lb 6/24/2009 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 74 Female 9/17/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 3/1/2008 61 Male 123 lb 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 9/1/2007 80 Male 238 lb 10/2/2009 Physician United States
Primary
Concomitant
Prostate Cancer Other Serious 8/13/2009 Male 188 lb 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 9/19/2009 51 Female 223 lb 10/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sickle Cell Anaemia With Crisis Hospitalization 7/19/2009 Male 10/9/2009 Physician United States
Primary
Secondary
Concomitant
Peritonitis Other Serious 3/31/2009 62 Female 11/3/2009 Other Health Professional United States
Primary
Concomitant
Completed Suicide Death 1/1/2008 74 Male 1/8/2010 Physician United States
Primary
Secondary
Weight Fluctuation Other Serious 12/1/2009 86 Male 1/11/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 64 Male 1/8/2010 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 62 Male 1/12/2010 United States
Primary
Concomitant
Small Intestinal Haemorrhage Life Threatening 12/23/2008 78 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 34 Male 161 lb 1/25/2010 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2007 59 Male 273 lb 1/25/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Staphylococcal Infection 6/1/2009 Female 115 lb 1/30/2010 United States
Primary
Concomitant
Hypotension Hospitalization 52 Female 8/13/2010 Other Health Professional United States
Primary
Secondary
Interacting
Bone Marrow Oedema Other Serious 52 Female 8/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 8/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Other Serious 8/1/2005 53 Male 212 lb 8/27/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus 3/1/2008 51 Female 139 lb 8/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Pruritus Male 260 lb 8/27/2010 United States
Primary
Concomitant
Feeling Hot 11/5/2009 66 Female 8/28/2010 United States
Primary
Concomitant
Flushing 12/1/2009 62 230 lb 8/28/2010 United States
Primary
Concomitant
Pruritus 7/1/2009 72 Female 158 lb 8/29/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 67 Male 156 lb 8/30/2010 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 8/13/2010 54 Male 168 lb 9/30/2010 Physician United States
Primary
Concomitant
Drug Ineffective 72 Female 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Diverticulitis Other Serious 1/1/2010 78 Female 10/29/2010 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/20/2010 68 Female 11/1/2010 Physician
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 9/13/2010 78 Male 188 lb 11/2/2010 Physician United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Other Serious 12/1/2008 63 Male 146 lb 11/2/2010 United States
Primary
Concomitant
Interacting
Vitamin B12 Deficiency Other Serious 1/1/2008 68 Female 157 lb 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Life Threatening 10/1/2010 71 Female 170 lb 11/5/2010 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 75 Female 11/8/2010 Consumer United States
Primary
Concomitant
Wound Dehiscence Other Serious 10/1/2007 68 Male 159 lb 11/9/2010 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 11/9/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 4/4/2007 46 Female 11/11/2010 Lawyer United States
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2007 69 Male 11/11/2010 Lawyer United States
Primary
Concomitant
Thrombophlebitis Superficial Hospitalization 63 Male 146 lb 11/13/2010 United States
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2009 75 Male 11/23/2010 Consumer United States
Primary
Concomitant
Syncope Other Serious 3/1/2008 54 Male 11/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 8/29/2010 64 Female 175 lb 11/22/2010 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 63 146 lb 11/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Suspiciousness Other Serious 47 Male 12/13/2010 Consumer United States
Primary
Concomitant
Cardiac Arrest Death 7/20/2010 12/15/2010 Physician United States
Primary
Concomitant
Wheezing Other Serious 1/1/2008 36 Male 289 lb 12/15/2010 Other Health Professional United States
Primary
Concomitant
Ocular Hyperaemia 11/1/2010 77 Female 12/16/2010 Consumer
Primary
Concomitant
Rash Hospitalization 2/1/2010 43 Male 256 lb 12/16/2010 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/31/2008 48 Female 159 lb 12/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 12/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Protein Total Decreased Other Serious 12/1/2010 Female 12/27/2010 Pharmacist United States
Primary
Concomitant
Protein Total Decreased Other Serious 12/1/2010 Female 12/30/2010 Pharmacist United States
Primary
Concomitant
Toxicity To Various Agents Death 37 Male 1/4/2011 Physician United States
Primary
Secondary
Syncope Hospitalization 1/1/2008 28 Female 1/13/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Other Serious 1/31/2008 48 Female 159 lb 1/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Diabetic Neuropathy Other Serious 67 Female 1/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 4/4/2007 46 Female 144 lb 1/31/2011 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 9/22/2010 80 Male 170 lb 2/14/2011 Physician United States
Primary
Secondary
Concomitant
Hypovolaemia Other Serious 2/29/2008 39 Female 143 lb 2/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Duodenal Perforation Other Serious 1/1/2009 69 Female 2/25/2011 Physician Canada
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/1/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Rhabdomyolysis Hospitalization 63 Male 146 lb 3/1/2011 Pharmacist United States
Primary
Concomitant
Interacting
Aplasia Pure Red Cell Other Serious 10/1/2010 61 Male 3/1/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Qt Prolonged Hospitalization 63 Male 146 lb 3/1/2011 Other Health Professional United States
Primary
Concomitant
Interacting
Anaemia Death 12/1/2010 3/1/2011 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Death Male 3/1/2011 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious 9/22/2010 80 Male 170 lb 3/3/2011 Consumer United States
Primary
Secondary
Concomitant
Adverse Drug Reaction Death 37 Male 3/4/2011 Other Health Professional United States
Primary
Secondary
Fear Other Serious 4/28/2008 73 Male 161 lb 3/4/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 4/28/2008 73 Male 161 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 10/1/2007 48 Female 159 lb 3/4/2011 Lawyer United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 63 Male 146 lb 3/9/2011 Pharmacist United States
Primary
Secondary
Concomitant
Transplant Failure Other Serious 11/12/2009 67 Female 273 lb 3/15/2011 Consumer United States
Primary
Secondary
Concomitant
Cardiac Arrest Other Serious 11/6/2007 50 Male 3/15/2011 Lawyer United States
Primary
Concomitant
Confusional State Other Serious 11/18/2008 63 Female 130 lb 3/18/2011 Physician United States
Primary
Concomitant
Diabetes Mellitus Other Serious Male 3/18/2011 Physician United States
Primary
Concomitant
Thrombotic Microangiopathy Other Serious 1/1/2010 59 Male 194 lb 3/23/2011 Physician United States
Primary
Secondary
Concomitant
Aspergillosis Hospitalization 1/27/2011 71 Female 99 lb 3/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 63 Male 146 lb 3/30/2011 Pharmacist United States
Primary
Secondary
Concomitant
Blood Pressure Inadequately Controlled Hospitalization Female 3/24/2011 United States
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 44 Female 4/14/2011 Physician United States
Primary
Secondary
Concomitant
Muscle Haemorrhage Hospitalization 3/19/2011 94 Female 103 lb 3/23/2011 Pharmacist United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 44 Female 4/18/2011 Physician United States
Primary
Concomitant
Drug Ineffective 4/14/2011 67 Male 236 lb 4/25/2011 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Oliguria Hospitalization 11/12/2009 67 Female 273 lb 4/25/2011 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 4/25/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 12/1/2008 63 Male 146 lb 5/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 63 Male 146 lb 5/31/2011 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 4/2/2011 60 Female 137 lb 6/15/2011 Physician United States
Primary
Concomitant
Bone Marrow Oedema Other Serious 52 Female 7/5/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Other Serious 5/1/1997 33 Female 10/12/2011 Pharmacist United States
Primary
Concomitant
Interacting
Hernia Hospitalization Female 161 lb 11/11/2011 Pharmacist United States
Primary
Concomitant
Nasopharyngitis 2/1/2012 59 Female 145 lb 2/21/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 6/1/2011 77 Male 134 lb 4/3/2012 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2009 69 Male 4/4/2012 Pharmacist United States
Primary
Concomitant
Interacting
Vomiting Hospitalization 11/22/2010 67 Female 145 lb 5/8/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Abdominal Pain Upper 6/1/2011 77 Male 134 lb 5/10/2012 Consumer United States
Primary
Concomitant
Feeling Abnormal Other Serious 5/1/2012 61 Male 240 lb 5/16/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Other Serious 79 Male 5/30/2012 Other Health Professional United States
Primary
Concomitant
Interacting
Insomnia Other Serious 1/1/2012 61 Male 229 lb 6/5/2012 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 45 Female 7/2/2012 Physician United States
Primary
Concomitant
Burning Sensation 6/30/2012 52 Female 164 lb 7/6/2012 Consumer United States
Primary
Secondary
Concomitant
Flushing Other Serious 7/1/2012 80 Female 161 lb 7/13/2012 Consumer United States
Primary
Concomitant
Feeling Hot Other Serious 7/1/2012 80 Female 161 lb 7/16/2012 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Death 3/17/2009 67 Female 273 lb 9/5/2012 Consumer Us
Primary
Secondary
Concomitant
Sepsis Death 11/12/2009 67 Female 273 lb 9/12/2012 Physician Us
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/18/2011 52 Male 260 lb 9/13/2012 Physician Us
Primary
Concomitant
Hypertension Hospitalization 2011 Male 194 lb 10/10/2012 Physician Us
Primary
Concomitant
Peripheral Arterial Occlusive Disease Death 10/2005 Male 295 lb 10/3/2012 Consumer Us
Primary
Concomitant
Restless Legs Syndrome Other Serious 2012 62 Male 229 lb 10/9/2012 Physician Us
Primary
Concomitant
Kidney Transplant Rejection Other Serious 12/30/2011 53 Female 141 lb 12/14/2012 Pharmacist Us
Primary
Concomitant
Tremor 2012 62 Male 247 lb 8/28/2012 Consumer Us
Primary
Concomitant
Thrombotic Microangiopathy Hospitalization 8/30/2012 Physician Us
Primary
Concomitant
Stent Placement Other Serious 2007 58 Male 249 lb 8/29/2012 Consumer Us
Primary
Concomitant
Death Death 8/29/2012 83 Female 78 lb 9/5/2012 Pharmacist Us
Primary
Concomitant
Neuropathy Peripheral Other Serious 8/2012 Female 9/6/2012 Other Health Professional Us
Primary
Concomitant
Myocardial Infarction Other Serious 10/2011 Female 9/5/2012 Physician Us
Primary
Secondary
Concomitant

Drug Data