Hydralazine Hcl combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tremor Hospitalization 12/7/2005 74 Male 213 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 10/11/2005 78 Male 6/29/2006 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Renal Failure Acute Hospitalization 5/24/2006 70 Male Pharmacist United States
Primary
Secondary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Other Serious 75 Female 133 lb 10/10/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/11/2006 75 Female 133 lb 10/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Discolouration 57 Male 11/13/2006 Consumer United States
Primary
Secondary
Concomitant
Neutropenia Hospitalization 12/4/2006 Female 176 lb 12/5/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 8/25/2006 Male 200 lb 9/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dizziness 71 Male 12/28/2006 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 9/1/2006 80 Male 12/28/2006 Consumer United States
Primary
Concomitant
Gynaecomastia Other Serious 9/26/2006 64 Male 242 lb 9/26/2006 Pharmacist United States
Primary
Concomitant
Thermal Burn Other Serious 1/1/2006 Male 219 lb 5/22/2007 Consumer United States
Primary
Concomitant
Pain In Extremity 1/1/2007 55 Male 228 lb 6/7/2007 Consumer United States
Primary
Concomitant
Blood Pressure Increased Other Serious 10/1/2006 82 Female 130 lb 7/9/2007 United States
Primary
Concomitant
Death Hospitalization 57 Female 8/20/2007 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 57 Female 263 lb 8/30/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 67 Male 217 lb 9/11/2007 Consumer United States
Primary
Concomitant
Drug Ineffective 5/16/2007 80 Female 10/3/2007 Consumer United States
Primary
Concomitant
Weight Decreased 57 Female 263 lb 10/5/2007 Other Health Professional United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 12/3/2007 Consumer United States
Primary
Concomitant
Nasopharyngitis 11/23/2007 Male 2/12/2008 Consumer United States
Primary
Concomitant
Swelling 11/1/2007 69 Male 234 lb 3/11/2008 Consumer United States
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Swollen Tongue Other Serious 5/12/2008 57 Male 197 lb 5/28/2008 United States
Primary
Concomitant
Vomiting Death 3/17/2008 70 Male 5/28/2008 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 11/6/2007 Female 204 lb 5/12/2008 Pharmacist United States
Primary
Concomitant
Wheezing Other Serious 1/1/2005 Male 7/1/2008 Physician United States
Primary
Concomitant
Cardiac Failure Other Serious 61 Male 8/27/2008 United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 9/8/2008 Male 10/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Required Intervention 5/3/2008 57 Male 197 lb 7/17/2008 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 11/10/2008 Pharmacist United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 61 Male 11/21/2008 Italy
Primary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 11/26/2008 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2008 80 Female 215 lb 11/19/2008 Pharmacist United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization Female 179 lb 1/9/2009 Consumer United States
Primary
Concomitant
Thyroid Function Test Abnormal Hospitalization 12/24/2008 Female 179 lb 1/21/2009 Physician United States
Primary
Concomitant
Respiratory Failure Other Serious 11/1/2007 63 Male 179 lb 2/2/2009 Pharmacist United States
Primary
Concomitant
Visual Impairment Other Serious 4/26/2008 45 Female 198 lb 2/5/2009 United States
Primary
Concomitant
Vomiting Other Serious 5/1/2007 68 Male 2/20/2009 Lawyer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 2/23/2009 Other Health Professional Italy
Primary
Concomitant
Ventricular Dysfunction Other Serious 61 Male 2/24/2009 Physician United States
Primary
Concomitant
Chest Discomfort Hospitalization 11/12/2008 Female 3/27/2009 Physician United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 11/26/2008 64 Male 256 lb 4/29/2009 Physician United Kingdom
Primary
Concomitant
Renal Injury Other Serious 3/21/2009 Female 168 lb 6/18/2009 United States
Primary
Concomitant
Mental Status Changes Required Intervention 5/18/2009 73 Female 126 lb 5/18/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 3/21/2009 Female 168 lb 6/29/2009 United States
Primary
Concomitant
Renal Function Test Abnormal Disability 1/1/2006 Male 7/6/2009 Consumer United States
Primary
Concomitant
Myositis Other Serious 3/7/2009 Female 124 lb 7/13/2009 Physician United Kingdom
Primary
Concomitant
Vomiting Death 86 Female 7/20/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 7/1/1998 41 Female 233 lb 7/27/2009 United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/3/2009 United States
Primary
Concomitant
Wheezing 7/1/2009 Female 8/17/2009 Consumer
Primary
Concomitant
Tonic Clonic Movements Other Serious 7/31/2009 Male 8/12/2009 Physician United States
Primary
Concomitant
Respiratory Failure Hospitalization 80 Female 8/13/2009 Consumer United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 5/4/2006 46 Male 310 lb 8/24/2009 United States
Primary
Concomitant
Weight Increased Other Serious 7/22/2008 69 Male 8/27/2009 Physician United States
Primary
Secondary
Concomitant
Sepsis Other Serious 11/1/2007 63 Male 179 lb 8/28/2009 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 45 Male 8/25/2009 United States
Primary
Concomitant
Unevaluable Event Death 71 Male 8/23/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 9/3/2009 United States
Primary
Concomitant
Wheezing 7/1/2009 Female 9/22/2009 Consumer
Primary
Concomitant
Vomiting Death 86 Female 9/23/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Swelling Other Serious 1/1/2009 Female 10/15/2009 Consumer United States
Primary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 10/9/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/9/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 1/22/2008 57 Male 10/16/2009 United States
Primary
Concomitant
Vomiting Death 1/22/2008 57 Male 10/22/2009 United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Wheezing Hospitalization 9/7/2008 53 Male 243 lb 10/27/2009 United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 1/22/2008 57 Male 11/4/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 57 Male 11/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/22/2008 57 Male 11/20/2009 United States
Primary
Concomitant
Wheezing Other Serious 1/1/2005 Male 12/1/2009 Physician United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 6/10/2009 68 Female 183 lb 11/16/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/1/2007 68 Male 12/22/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Other Serious 1/1/2007 50 Male 1/7/2010 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 12/14/2007 69 Male 3/4/2010 Lawyer United States
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Product Substitution Issue Disability 3/16/2010 63 Male 155 lb 4/6/2010 Pharmacist United States
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 1/1/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/24/2008 69 Male 3/19/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 8/24/2008 69 Male 4/19/2010 Physician United States
Primary
Secondary
Concomitant
Vitamin B12 Decreased Hospitalization 80 Female 5/6/2010 United States
Primary
Concomitant
Vomiting Hospitalization 66 Male 5/11/2010 United States
Primary
Concomitant
Renal Failure Chronic Other Serious 11/19/2007 64 Male 5/24/2010 Lawyer United States
Primary
Concomitant
Skin Discolouration Hospitalization 5/6/2010 73 Male 170 lb 5/25/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Hospitalization 1/22/2008 57 Male 5/21/2010 United States
Primary
Concomitant
Vomiting Other Serious 1/2/2007 69 Male 187 lb 6/7/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 28 Male 6/11/2010 Lawyer United States
Primary
Concomitant
Tremor 12/1/2007 35 Male 249 lb 6/21/2010 Other Health Professional United States
Primary
Concomitant
Hypertension Other Serious Female 6/30/2010 United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 7/5/2010 67 Male 285 lb 7/5/2010 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 9/1/2006 79 Male 152 lb 7/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/22/2008 57 Male 7/19/2010 United States
Primary
Concomitant
Vomiting Hospitalization 66 Male 7/26/2010 United States
Primary
Concomitant
Vomiting Hospitalization 86 Female 7/26/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/1998 41 Female 218 lb 8/6/2010 United States
Primary
Concomitant
Vomiting Other Serious 12/14/2007 69 Male 187 lb 10/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 45 Male 1/18/2011 Pharmacist United States
Primary
Concomitant
Bone Disorder Other Serious Female 1/26/2011 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 75 Female 1/26/2011 Consumer United States
Primary
Concomitant
Abdominal Distension Other Serious 7/11/2010 62 Male 1/27/2011 Consumer Canada
Primary
Concomitant
Blood Disorder Other Serious 11/19/2007 64 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Dizziness Hospitalization 1/27/2007 32 Female 209 lb 1/28/2011 Physician United States
Primary
Secondary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 6/10/2009 68 Female 183 lb 11/17/2010 Consumer United States
Primary
Secondary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 6/10/2009 68 Female 183 lb 11/16/2010 Consumer United States
Primary
Secondary
Concomitant
Blood Potassium Increased Hospitalization 7/14/2010 56 Male 272 lb 3/25/2011 Physician United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 1/31/2004 43 Female 3/31/2011 Physician United States
Primary
Concomitant
Fear Death 12/26/2004 54 Male 205 lb 4/29/2011 Consumer United States
Primary
Concomitant
Anaemia Other Serious 2/25/2011 73 Female 205 lb 5/4/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization Female 217 lb 5/6/2011 Consumer United States
Primary
Concomitant
Nephrolithiasis Other Serious 3/29/2004 Male 5/9/2011 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 2/1/2011 48 Female 5/11/2011 Other Health Professional United States
Primary
Concomitant
Fear Of Death Other Serious Male 5/19/2011 Lawyer United States
Primary
Concomitant
Cardiomyopathy Other Serious 2/1/2011 49 Female 5/22/2011 Other Health Professional United States
Primary
Concomitant
Blood Pressure Decreased Other Serious 3/3/2011 67 Male 5/23/2011 Consumer United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Hospitalization 1/22/2011 61 Male 178 lb 5/26/2011 Physician Switzerland
Primary
Secondary
Concomitant
Emotional Distress Other Serious Male 5/26/2011 Lawyer United States
Primary
Concomitant
Cardiomyopathy Hospitalization 2/1/2011 49 Female 6/2/2011 Physician United States
Primary
Concomitant
Blood Pressure Increased Hospitalization 22 Female 6/8/2011 Other Health Professional Philippines
Primary
Concomitant
Emotional Distress Other Serious 6/24/2006 43 Male 6/16/2011 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 4/4/2011 75 Male 6/17/2011 Physician United States
Primary
Secondary
Concomitant
Fear Other Serious 48 Male 160 lb 7/5/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 6/24/2006 43 Male 7/11/2011 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/27/2007 32 Female 209 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 9/1/2006 79 Male 152 lb 7/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 57 Male 173 lb 7/22/2011 Other Health Professional United States
Primary
Concomitant
Tonsillar Hypertrophy Other Serious 3/29/2004 42 Male 7/29/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 12/26/2004 54 Male 205 lb 8/2/2011 Other Health Professional United States
Primary
Concomitant
Cardiomyopathy Other Serious 2/1/2011 49 Female 9/14/2011 Other Health Professional United States
Primary
Concomitant
Sneezing 5/11/2011 64 Female 9/14/2011 Consumer United States
Primary
Concomitant
Concomitant Disease Progression Life Threatening 7/14/2010 56 Male 272 lb 9/19/2011 Physician United States
Primary
Secondary
Concomitant
Hyperlipidaemia 5/1/2007 49 Male 9/22/2011 Consumer United States
Primary
Concomitant
Multiple Myeloma Death Female 211 lb 9/26/2011 Physician United States
Primary
Secondary
Concomitant
Erection Increased 8/1/2011 45 Male 10/6/2011 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 9/11/2011 82 Female 177 lb 9/27/2011 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 58 Male 406 lb 10/10/2011 Consumer United States
Primary
Concomitant
Chest Pain Other Serious 44 Female 10/13/2011 Physician Brazil
Primary
Secondary
Blood Triglycerides Increased Hospitalization 44 Female 10/13/2011 Brazil
Primary
Secondary
Cardiac Failure Acute Hospitalization 6/2/2011 42 Male 196 lb 10/19/2011 Physician Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 6/2/2011 42 Male 196 lb 10/19/2011 Physician Brazil
Primary
Secondary
Concomitant
Concomitant Disease Progression Hospitalization 7/14/2010 56 Male 272 lb 10/26/2011 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Increased Hospitalization 44 Female 10/27/2011 Physician Brazil
Primary
Concomitant

Drug Data