Humira combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toe Amputation Hospitalization 9/1/2005 Female 220 lb 1/13/2006 United States
Primary
Concomitant
Sepsis Death Female 132 lb 2/8/2006 United Kingdom
Primary
Concomitant
Faecaloma Other Serious 1/1/2005 Female 145 lb 2/10/2006 United States
Primary
Concomitant
Joint Arthroplasty Hospitalization 5/10/2004 Female 165 lb 2/28/2006 Physician Germany
Primary
Concomitant
Faecaloma Other Serious 8/1/2005 Female 145 lb 3/24/2006 Physician United States
Primary
Concomitant
Osteomyelitis Other Serious 5/24/2005 35 Female 4/7/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Spinal Column Stenosis Life Threatening 1/1/2005 Female 125 lb 7/24/2006 Physician United States
Primary
Concomitant
Labyrinthitis Hospitalization 7/13/2006 Female 160 lb 8/4/2006 Consumer Canada
Primary
Secondary
Concomitant
Sepsis Death Female 132 lb 8/24/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 8/1/2006 Female 8/28/2006 Physician United States
Primary
Concomitant
Mouth Ulceration Other Serious 7/1/2006 Female 106 lb 9/6/2006 Other Health Professional United States
Primary
Concomitant
Staphylococcal Infection Death 7/21/2006 Female 10/13/2006 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/1/2005 Female 251 lb 10/26/2006 Consumer United States
Primary
Concomitant
Staphylococcal Infection Death 7/21/2006 Female 172 lb 10/30/2006 Physician United Kingdom
Primary
Concomitant
Rash Pustular Hospitalization 11/6/2006 54 Male 11/21/2006 Physician Sweden
Primary
Concomitant
Myocardial Infarction Death 3/26/2006 Female 267 lb 12/28/2006 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 6/12/2006 Female 120 lb 1/16/2007 Consumer Canada
Primary
Concomitant
Pain Hospitalization 8/1/2006 Female 1/16/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 1/1/2006 Male 195 lb 2/2/2007 Consumer Canada
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 6/12/2006 Female 120 lb 4/12/2007 Consumer Canada
Primary
Concomitant
Tachycardia Other Serious 12/13/2006 Female 90 lb 5/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Other Serious 12/13/2006 Female 90 lb 5/4/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 5/22/2007 Consumer Canada
Primary
Concomitant
Surgery Other Serious 1/1/2007 Male 168 lb 5/30/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/30/2007 Female 263 lb 6/9/2007 Physician Canada
Primary
Concomitant
Renal Impairment Hospitalization Female 6/26/2007 Consumer Canada
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 6/1/2006 79 Male 195 lb 6/13/2007 Physician United States
Primary
Concomitant
Procedural Pain Other Serious 7/18/2006 Female 165 lb 8/1/2007 Physician United States
Primary
Concomitant
Rash Pustular Hospitalization 11/6/2006 Male 8/17/2007 Physician Sweden
Primary
Concomitant
Vision Blurred Hospitalization Female 9/17/2007 Physician United States
Primary
Concomitant
Renal Failure Life Threatening 8/16/2007 Male 9/27/2007 Australia
Primary
Concomitant
Upper Extremity Mass Hospitalization 6/19/2007 Male 246 lb 10/9/2007 Canada
Primary
Concomitant
Renal Failure Hospitalization 7/9/2007 Male 11/30/2007 Australia
Primary
Concomitant
Femoral Hernia Hospitalization 12/16/2003 Female 170 lb 12/10/2007 United Kingdom
Primary
Concomitant
Injection Site Pruritus 8/14/2007 Male 180 lb 12/14/2007 United States
Primary
Concomitant
Injection Site Pruritus 9/17/2007 Male 208 lb 12/14/2007 United States
Primary
Concomitant
Chest Pain 9/19/2007 Female 190 lb 12/14/2007 United States
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 12/20/2007 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 7/5/2007 Male 12/20/2007 Australia
Primary
Concomitant
Sepsis Other Serious 4/1/2007 Female 12/21/2007 Other Health Professional France
Primary
Secondary
Visual Acuity Reduced Other Serious Female 12/27/2007 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 1/30/2008 Physician United Kingdom
Primary
Concomitant
Thoracic Vertebral Fracture Hospitalization 6/1/1998 53 Female 143 lb 2/4/2008 Physician United States
Primary
Concomitant
Rash 12/17/2007 Female 303 lb 3/14/2008 United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 11/1/2007 Female 3/15/2008 Consumer United States
Primary
Concomitant
Skin Ulcer 2/6/2008 Male 150 lb 3/15/2008 United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2007 Female 3/19/2008 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2007 Female 3/28/2008 United Kingdom
Primary
Concomitant
Urticaria Other Serious 1/31/2008 Female 3/28/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 51 Female 5/1/2008 Consumer United States
Primary
Concomitant
Adenocarcinoma Pancreas Life Threatening 56 Male 135 lb 5/15/2008 Other Health Professional Canada
Primary
Concomitant
Arthropathy Hospitalization 4/9/2008 Female 5/16/2008 Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2007 Female 5/23/2008 United Kingdom
Primary
Concomitant
Bone Erosion Hospitalization Male 6/2/2008 Canada
Primary
Concomitant
Rash Other Serious 4/6/2008 Male 168 lb 6/4/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2004 Female 260 lb 6/9/2008 Consumer United States
Primary
Concomitant
Vertigo 1/1/2005 Male 136 lb 6/12/2008 Physician United States
Primary
Concomitant
Paraesthesia 3/15/2008 Female 360 lb 6/12/2008 United States
Primary
Concomitant
Drug Effect Decreased 2/10/2008 Male 260 lb 6/12/2008 United States
Primary
Concomitant
Oedema Peripheral 4/4/2008 Male 235 lb 6/12/2008 United States
Primary
Concomitant
Accidental Exposure 5/7/2008 Female 210 lb 6/13/2008 Consumer United States
Primary
Concomitant
Injection Site Warmth 4/27/2008 Female 137 lb 6/13/2008 Consumer United States
Primary
Concomitant
Vomiting 6/1/2006 Female 128 lb 6/13/2008 United States
Primary
Concomitant
Bone Erosion Hospitalization Male 6/17/2008 Canada
Primary
Concomitant
Pharyngolaryngeal Pain Other Serious 4/6/2008 Male 162 lb 6/23/2008 United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 Female 121 lb 7/10/2008 United States
Primary
Secondary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/17/2008 United States
Primary
Concomitant
Pemphigoid Other Serious 4/6/2008 Male 162 lb 7/22/2008 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 5/1/2008 Female 123 lb 7/23/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 5/1/2008 Female 121 lb 7/28/2008 United States
Primary
Secondary
Concomitant
Lung Disorder Death 11/17/2007 Male 86 lb 8/7/2008 United Kingdom
Primary
Concomitant
Wound Other Serious 4/6/2008 Male 162 lb 8/27/2008 United States
Primary
Concomitant
Oral Infection Other Serious 7/1/2008 Female 157 lb 9/10/2008 United States
Primary
Concomitant
Oral Infection Other Serious 7/1/2008 Female 157 lb 9/11/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2005 Female 120 lb 9/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Metrorrhagia 4/11/2008 Female 198 lb 9/12/2008 United States
Primary
Concomitant
Blood Glucose Increased 6/6/2008 Male 180 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Urticaria 6/4/2008 Male 183 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Urinary Retention 3/10/2008 Female 206 lb 9/12/2008 Consumer United States
Primary
Concomitant
Contusion 6/23/2008 Male 175 lb 9/12/2008 Consumer United States
Primary
Concomitant
Injection Site Pain 11/1/2007 Female 154 lb 9/12/2008 Consumer United States
Primary
Concomitant
Urinary Hesitation 1/1/2008 Female 9/12/2008 United States
Primary
Concomitant
Diarrhoea 1/1/2007 Male 250 lb 9/12/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 7/1/2008 Male 190 lb 9/12/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 8/9/2008 Female 210 lb 9/12/2008 United States
Primary
Concomitant
Injection Site Swelling 2/1/2008 Male 152 lb 9/13/2008 Consumer United States
Primary
Concomitant
Urinary Tract Infection 8/1/2007 Female 206 lb 9/13/2008 Consumer United States
Primary
Concomitant
Red Blood Cell Sedimentation Rate Increased Hospitalization 7/1/2008 Female 310 lb 9/22/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 10/1/2004 Female 260 lb 9/25/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious Female 115 lb 10/29/2008 Canada
Primary
Concomitant
Lung Neoplasm Malignant Death 8/1/2008 Male 11/4/2008 United States
Primary
Concomitant
Weight Decreased Other Serious Female 115 lb 11/18/2008 Canada
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/25/2008 Australia
Primary
Concomitant
Procedural Complication 1/1/2008 Female 145 lb 12/12/2008 Consumer United States
Primary
Concomitant
Underdose Female 107 lb 12/12/2008 United States
Primary
Concomitant
Drug Ineffective 1/1/2007 Male 178 lb 12/12/2008 United States
Primary
Concomitant
Fatigue 11/14/2008 Male 12/12/2008 United States
Primary
Concomitant
Glioblastoma Multiforme Other Serious 9/1/2008 Male 265 lb 12/31/2008 Australia
Primary
Concomitant
Glioblastoma Multiforme Other Serious 9/1/2008 Male 265 lb 1/16/2009 Australia
Primary
Concomitant
Wound Dehiscence Other Serious 8/1/2008 Male 170 lb 1/20/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/1/2008 Male 170 lb 1/23/2009 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 8/1/2008 Male 170 lb 1/28/2009 Physician United States
Primary
Concomitant
Fistula Other Serious Female 2/5/2009 Germany
Primary
Concomitant
Glioblastoma Multiforme Other Serious 9/26/2008 Male 265 lb 2/6/2009 Australia
Primary
Concomitant
Glioblastoma Multiforme Other Serious 9/26/2008 Male 265 lb 2/20/2009 Australia
Primary
Concomitant
Small Cell Lung Cancer Metastatic Death 11/8/2008 Female 146 lb 2/27/2009 Physician United States
Primary
Concomitant
Nasal Polyps Other Serious 1/1/2008 Female 160 lb 3/4/2009 Canada
Primary
Concomitant
Oral Infection Other Serious 7/1/2008 Female 157 lb 3/12/2009 United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 Female 174 lb 3/13/2009 United States
Primary
Concomitant
Osteomyelitis 10/1/2008 Female 172 lb 3/13/2009 Consumer United States
Primary
Concomitant
Injection Site Haematoma 6/23/2008 Male 185 lb 3/13/2009 United States
Primary
Concomitant
Pain 1/1/2006 Female 220 lb 3/14/2009 Consumer United States
Primary
Concomitant
Pain 12/19/2008 Male 3/14/2009 United States
Primary
Concomitant
Exostosis 2/7/2009 Female 190 lb 3/14/2009 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 2/1/2009 Female 174 lb 3/17/2009 United States
Primary
Concomitant
Metastases To Liver Other Serious Female 145 lb 4/16/2009 Canada
Primary
Concomitant
Withdrawal Syndrome Other Serious 12/19/2008 Female 126 lb 5/28/2009 United States
Primary
Concomitant
Pyrexia Other Serious 5/16/2009 Male 5/28/2009 Other Health Professional Australia
Primary
Secondary
Concomitant
Osteomyelitis 10/1/2008 Female 172 lb 6/11/2009 Physician United States
Primary
Concomitant
Rash Pustular 1/1/2008 Male 6/11/2009 Consumer United States
Primary
Concomitant
Septic Shock Other Serious 10/27/2007 59 Female 8/3/2009 Lawyer United States
Primary
Concomitant
Metastases To Bone Other Serious 9/7/2009 72 Female 9/17/2009 Physician Switzerland
Primary
Concomitant
Pneumonia Hospitalization 6/6/2009 Female 163 lb 9/18/2009 Other Health Professional United States
Primary
Concomitant
Vomiting 6/23/2009 Female 110 lb 9/19/2009 United States
Primary
Concomitant
Stomatitis 7/1/2007 Female 174 lb 9/19/2009 United States
Primary
Concomitant
Rash Pustular 1/1/2008 Male 157 lb 9/19/2009 United States
Primary
Concomitant
Dysentery 7/1/2009 Male 135 lb 9/19/2009 Consumer United States
Primary
Concomitant
Wound Haemorrhage 4/1/2009 Female 9/19/2009 Consumer United States
Primary
Concomitant
Rectal Cancer Metastatic Other Serious 9/7/2009 72 Female 10/1/2009 Physician Switzerland
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 9/1/2007 Female 10/13/2009 United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 10/16/2006 Female 215 lb 10/22/2009 United States
Primary
Concomitant
Ill-defined Disorder Hospitalization Female 11/2/2009 Canada
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 11/2/2009 Australia
Primary
Concomitant
Nausea Other Serious 1/1/2007 Female 75 lb 11/20/2009 Consumer United States
Primary
Secondary
Concomitant
Ill-defined Disorder Hospitalization Female 222 lb 11/25/2009 Canada
Primary
Concomitant
Pulmonary Embolism Other Serious 3/9/2009 Male 154 lb 11/25/2009 United Kingdom
Primary
Concomitant
Surgery Hospitalization Female 222 lb 12/7/2009 Canada
Primary
Concomitant
Wound Haemorrhage 4/1/2009 12/10/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Withdrawal Maintenance Therapy Hospitalization Female 145 lb 12/17/2009
Primary
Concomitant
Neoplasm Malignant Hospitalization Female 222 lb 12/29/2009 Canada
Primary
Concomitant
Uterine Infection Other Serious 10/8/2009 Female 223 lb 1/18/2010 United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2009 Female 185 lb 1/29/2010 Canada
Primary
Secondary
Concomitant
Weight Increased 10/15/2009 Female 254 lb 1/30/2010 United States
Primary
Concomitant
Small Intestine Carcinoma Other Serious 8/1/2009 Female 160 lb 1/30/2010 United States
Primary
Concomitant
Weight Increased 10/15/2009 Female 254 lb 1/30/2010 United States
Primary
Concomitant
Nasopharyngitis 11/20/2009 Female 90 lb 1/30/2010 United States
Primary
Concomitant
Injection Site Pruritus 11/20/2009 Female 135 lb 1/30/2010 United States
Primary
Concomitant
White Blood Cell Count Increased Death 11/6/2009 Female 163 lb 2/12/2010 United Kingdom
Primary
Concomitant
Peritonitis Other Serious 11/27/2009 Female 2/19/2010 Canada
Primary
Concomitant
Renal Failure Life Threatening 7/5/2007 Male 2/23/2010 Australia
Primary
Concomitant

Drug Data