Humira combined with Metformin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Toe Amputation Hospitalization 9/1/2005 Female 220 lb 1/13/2006 United States
Primary
Concomitant
Lethargy Hospitalization 5/21/2005 Female 137 lb 3/10/2006 Other Health Professional United Kingdom
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 1/21/2006 Female 110 lb 4/6/2006 Consumer Canada
Primary
Concomitant
Optic Neuritis Retrobulbar Hospitalization 55 Male 4/7/2006 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/28/2005 76 Male 200 lb 2/2/2006 Physician United States
Primary
Concomitant
Mass Required Intervention 1/18/2006 61 Female 200 lb 6/16/2006 Physician United States
Primary
Secondary
Concomitant
Pulmonary Fibrosis Death 4/19/2006 Female 325 lb 7/7/2006 Physician Canada
Primary
Concomitant
Lethargy Other Serious 5/17/2005 Female 137 lb 8/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 5/1/2006 Female 176 lb 8/11/2006 Consumer Brazil
Primary
Concomitant
Urinary Tract Infection Other Serious 6/2/2005 Female 185 lb 8/23/2006 Consumer United States
Primary
Concomitant
Arthropathy Other Serious Female 149 lb 10/9/2006 Consumer Canada
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/1/2006 Female 160 lb 11/16/2006 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 5/1/2006 Female 195 lb 11/22/2006 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 10/31/2006 Female 11/22/2006 Consumer United States
Primary
Concomitant
Heart Rate Decreased Hospitalization 9/1/2006 Female 217 lb 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Pain Other Serious 11/2/2006 46 Female 12/29/2006 United States
Primary
Concomitant
Wound Secretion Other Serious 12/1/2006 Female 173 lb 3/22/2007 Physician United States
Primary
Concomitant
Urinary Tract Infection Other Serious Female 182 lb 3/29/2007 Pharmacist United Kingdom
Primary
Concomitant
Haemorrhage Hospitalization 3/27/2006 Female 130 lb 4/11/2007 Consumer United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization 9/1/2006 58 Male 7/3/2007 Physician Sweden
Primary
Secondary
Concomitant
Fungal Infection Other Serious 11/27/2006 Female 200 lb 9/7/2007 Consumer Canada
Primary
Concomitant
Sudden Cardiac Death Death 6/1/2006 Male 271 lb 9/26/2007 Germany
Primary
Concomitant
Thalassaemia Other Serious Male 9/27/2007 Belgium
Primary
Concomitant
Ischaemic Cerebral Infarction Other Serious 5/16/2006 66 Female 9/28/2007 Physician Germany
Primary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 10/26/2007 Brazil
Primary
Secondary
Concomitant
Rhinitis Other Serious 10/3/2007 50 Female 143 lb 11/2/2007 Brazil
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 9/1/2007 Male 11/12/2007 Consumer Germany
Primary
Concomitant
Joint Swelling Other Serious 6/15/2007 Female 20 lb 1/21/2008 United Kingdom
Primary
Concomitant
Localised Infection Other Serious 10/3/2006 Male 157 lb 1/21/2008 United Kingdom
Primary
Concomitant
Malaise Hospitalization 7/2/2007 Male 1/21/2008 United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 11/1/2007 Female 325 lb 3/14/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 2/1/2006 Male 178 lb 3/14/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 9/22/2006 Female 180 lb 3/14/2008 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective 11/1/2007 Female 180 lb 3/14/2008 Consumer United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 9/1/2007 Female 335 lb 3/14/2008 United States
Primary
Concomitant
Vomiting 11/1/2007 Female 224 lb 3/14/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 10/1/2007 Female 192 lb 3/14/2008 Consumer United States
Primary
Concomitant
Nasopharyngitis 12/12/2007 Female 200 lb 3/14/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 11/1/2007 Male 3/14/2008 Physician United States
Primary
Concomitant
Pain In Extremity 8/19/2007 Female 150 lb 3/14/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 8/1/2007 Female 156 lb 3/14/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 12/1/2007 Female 3/14/2008 United States
Primary
Concomitant
Skin Exfoliation 12/1/2006 Female 163 lb 3/14/2008 Physician United States
Primary
Concomitant
Smear Cervix Abnormal 3/10/2007 Female 178 lb 3/15/2008 Physician United States
Primary
Concomitant
Nasopharyngitis 1/1/2008 Female 158 lb 3/15/2008 Consumer United States
Primary
Concomitant
Road Traffic Accident 1/11/2008 Female 275 lb 3/15/2008 United States
Primary
Concomitant
Pain 1/18/2008 Female 156 lb 3/15/2008 Consumer United States
Primary
Concomitant
Drug Ineffective 10/1/2007 Female 171 lb 3/15/2008 Consumer United States
Primary
Concomitant
Accidental Exposure 1/24/2008 Female 3/15/2008 Consumer United States
Primary
Concomitant
Rectal Haemorrhage 12/1/2007 Female 170 lb 3/15/2008 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection 8/1/2007 Female 172 lb 3/15/2008 United States
Primary
Concomitant
Vision Blurred 5/1/2007 Male 240 lb 3/15/2008 United States
Primary
Concomitant
Accidental Exposure 1/31/2008 Female 195 lb 3/15/2008 Other Health Professional United States
Primary
Concomitant
Injection Site Pain 1/1/2006 Male 220 lb 3/15/2008 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion 1/1/2007 Female 170 lb 3/15/2008 United States
Primary
Concomitant
Stomatitis 2/12/2008 Female 137 lb 3/15/2008 United States
Primary
Concomitant
Pneumonia 12/1/2007 Female 351 lb 3/15/2008 United States
Primary
Concomitant
Mental Impairment 2/16/2008 3/15/2008 United States
Primary
Concomitant
Procedural Complication 2/25/2008 Female 190 lb 3/15/2008 Consumer United States
Primary
Concomitant
Sinusitis 1/26/2008 Male 260 lb 3/15/2008 United States
Primary
Concomitant
Injection Site Pruritus 1/1/2008 Female 150 lb 3/15/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral 1/1/2008 Female 135 lb 3/15/2008 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 3/17/2008 Male 3/28/2008 Belgium
Primary
Concomitant
Weight Decreased Other Serious 3/1/2008 43 Female 258 lb 6/6/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 3/3/2008 Female 231 lb 6/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Sensory Disturbance Other Serious 3/8/2008 Female 262 lb 6/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/22/2008 Male 8/21/2008 Canada
Primary
Concomitant
Throat Cancer Other Serious 1/18/2008 Male 181 lb 8/22/2008 United Kingdom
Primary
Concomitant
Breast Pain Other Serious 8/12/2008 Female 9/8/2008 Belgium
Primary
Concomitant
Foot Deformity Other Serious Female 9/8/2008 Brazil
Primary
Concomitant
Wound Infection Other Serious 10/30/2008 Male 183 lb 12/29/2008 Canada
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/29/2008 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infection Hospitalization 8/19/2007 Male 1/13/2009 United Kingdom
Primary
Concomitant
Localised Infection Other Serious 5/1/2008 Female 162 lb 1/16/2009 Consumer United States
Primary
Secondary
Concomitant
Immune System Disorder Hospitalization Female 1/21/2009 Brazil
Primary
Concomitant
Vomiting Other Serious 12/25/2008 Female 220 lb 1/30/2009 United States
Primary
Concomitant
Subdural Haematoma Hospitalization 7/26/2008 Female 2/4/2009 Germany
Primary
Secondary
Concomitant
Localised Infection Other Serious 5/1/2008 Female 162 lb 2/10/2009 Consumer United States
Primary
Secondary
Concomitant
Death Death 2/23/2009 Male 220 lb 2/26/2009 United Kingdom
Primary
Concomitant
Tendon Disorder Other Serious 12/10/2008 Female 165 lb 2/26/2009 Brazil
Primary
Concomitant
Weight Increased Other Serious 9/1/2008 Male 2/27/2009 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion Other Serious Female 155 lb 3/5/2009 Canada
Primary
Concomitant
Wound Infection Other Serious 10/30/2008 Male 183 lb 3/6/2009 Canada
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/8/2008 Female 7/7/2009 Physician United Kingdom
Primary
Concomitant
Speech Disorder Other Serious 1/1/2007 157 lb 7/27/2009 United States
Primary
Secondary
Oral Pain Hospitalization 6/1/2009 Female 160 lb 7/27/2009 Canada
Primary
Concomitant
Weight Increased Other Serious 9/30/2008 54 Male 7/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Alveolitis Allergic Hospitalization 4/18/2009 Female 183 lb 7/29/2009 New Zealand
Primary
Secondary
Concomitant
Psoriasis Other Serious 8/1/2008 Female 7/30/2009 Other Health Professional United States
Primary
Concomitant
Tuberculosis Other Serious 7/1/2008 Male 7/31/2009 Other Health Professional United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 6/28/2009 Male 165 lb 8/3/2009 Other Health Professional South Africa
Primary
Concomitant
Weight Increased Other Serious 54 Male 7/28/2009 United Kingdom
Primary
Secondary
Concomitant
Cerebrovascular Accident Death 4/19/2009 Male 234 lb 8/11/2009 United Kingdom
Primary
Concomitant
Urticaria Hospitalization 1/1/2009 Male 170 lb 8/17/2009 United States
Primary
Concomitant
Urticaria Hospitalization 1/1/2009 Male 170 lb 8/19/2009 United States
Primary
Concomitant
Cholelithiasis Other Serious 5/1/2009 Female 220 lb 8/19/2009 United States
Primary
Concomitant
Alveolitis Allergic Hospitalization 4/18/2009 Female 183 lb 8/20/2009 New Zealand
Primary
Secondary
Concomitant
Gallbladder Disorder Other Serious 3/1/2009 Male 201 lb 8/20/2009 Brazil
Primary
Concomitant
Bronchial Carcinoma Hospitalization 7/3/2009 70 Male 9/25/2009 Germany
Primary
Concomitant
Vision Blurred Other Serious 6/28/2009 Male 165 lb 9/25/2009 Other Health Professional South Africa
Primary
Concomitant
Vomiting Hospitalization 5/7/2009 Female 10/1/2009 United Kingdom
Primary
Concomitant
Rheumatoid Lung Other Serious 9/24/2009 Female 187 lb 10/1/2009 Other Health Professional United States
Primary
Concomitant
Wound Drainage Other Serious 2/1/2009 Male 195 lb 10/2/2009 Consumer United States
Primary
Concomitant
Pustular Psoriasis Other Serious 4/1/2009 Female 198 lb 10/5/2009 Physician United Kingdom
Primary
Concomitant
Visual Acuity Reduced Other Serious Female 220 lb 10/5/2009 Brazil
Primary
Concomitant
Cerebrovascular Accident Death Male 234 lb 10/8/2009 United Kingdom
Primary
Concomitant
Bronchial Carcinoma Hospitalization 7/3/2009 70 Male 10/20/2009 Germany
Primary
Concomitant
Renal Impairment Other Serious 1/1/2009 Female 175 lb 11/6/2009 United States
Primary
Secondary
Concomitant
Bronchial Carcinoma Hospitalization 7/3/2009 Male 11/16/2009 Germany
Primary
Concomitant
Urticaria 10/5/2009 Female 12/9/2009 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 11/18/2009 Female 140 lb 12/14/2009 Canada
Primary
Concomitant
Paraesthesia Other Serious 11/18/2009 Female 140 lb 12/29/2009 Canada
Primary
Concomitant
Haematuria Life Threatening 9/1/2008 Female 265 lb 12/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 1/30/2009 Female 225 lb 12/31/2009 United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 1/1/2009 Female 225 lb 1/7/2010 United States
Primary
Concomitant
Benign Prostatic Hyperplasia Hospitalization 11/1/2008 Male 198 lb 1/22/2010 Germany
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/1/2009 Female 220 lb 1/25/2010 Brazil
Primary
Secondary
Concomitant
Ventricular Fibrillation Death 6/3/2009 Female 175 lb 1/28/2010 United Kingdom
Primary
Concomitant
Wisdom Teeth Removal Other Serious 7/1/2009 Female 154 lb 1/28/2010 Brazil
Primary
Concomitant
Headache 9/9/2009 Female 1/29/2010 Consumer Puerto Rico
Primary
Concomitant
Joint Range Of Motion Decreased 6/7/2009 Female 192 lb 1/29/2010 United States
Primary
Concomitant
Pruritus 8/9/2009 Female 168 lb 1/29/2010 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process 1/1/2008 Male 1/29/2010 Consumer United States
Primary
Concomitant
Rash 9/5/2009 Female 220 lb 1/29/2010 United States
Primary
Concomitant
Visual Impairment 6/1/2008 Male 196 lb 1/29/2010 United States
Primary
Concomitant
Injection Site Swelling 9/2/2009 Female 246 lb 1/29/2010 United States
Primary
Concomitant
Pain 8/1/2009 Male 330 lb 1/29/2010 United States
Primary
Concomitant
Drug Dose Omission 7/1/2009 Male 155 lb 1/29/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 9/10/2009 Male 194 lb 1/29/2010 Consumer United States
Primary
Concomitant
Drug Effect Decreased 11/1/2008 Female 144 lb 1/29/2010 Physician United States
Primary
Concomitant
Pain In Jaw 8/19/2009 Male 235 lb 1/29/2010 Consumer United States
Primary
Concomitant
Injection Site Pain 9/18/2009 Female 1/29/2010 Consumer United States
Primary
Concomitant
Injection Site Papule 1/1/2009 Female 171 lb 1/29/2010 Consumer United States
Primary
Concomitant
Musculoskeletal Stiffness 1/29/2010 Pharmacist United States
Primary
Concomitant
Drug Dose Omission 9/24/2009 Female 198 lb 1/29/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased 11/1/2007 Female 200 lb 1/29/2010 United States
Primary
Concomitant
Weight Increased 9/19/2009 Male 350 lb 1/29/2010 United States
Primary
Concomitant
Skin Fissures 7/1/2009 Female 172 lb 1/29/2010 United States
Primary
Concomitant
Pain In Extremity 9/10/2009 Female 225 lb 1/29/2010 United States
Primary
Concomitant
Vitamin D Deficiency 8/1/2009 Female 1/29/2010 Pharmacist United States
Primary
Secondary
Concomitant
Mass 10/5/2009 Female 170 lb 1/29/2010 United States
Primary
Concomitant
Musculoskeletal Pain 8/24/2009 Male 193 lb 1/29/2010 United States
Primary
Concomitant
Procedural Complication 10/6/2009 Female 207 lb 1/29/2010 United States
Primary
Concomitant
Subcutaneous Abscess Other Serious 1/1/2005 Male 140 lb 1/30/2010 United States
Primary
Concomitant
Muscle Spasms Female 175 lb 1/30/2010 Consumer United States
Primary
Concomitant
Oedema Peripheral 9/1/2009 Male 195 lb 1/30/2010 Consumer United States
Primary
Concomitant
Nasopharyngitis 10/1/2009 Female 192 lb 1/30/2010 Consumer United States
Primary
Concomitant
Influenza Female 1/30/2010 United States
Primary
Concomitant
Psoriasis 9/15/2009 Female 1/30/2010 United States
Primary
Concomitant

Drug Data