Herceptin combined with Zometa

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 4/1/2005 48 Female 117 lb 1/10/2006 Physician France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 1/13/2006 Physician Belgium
Primary
Concomitant
Neuropathy Peripheral 53 Female 2/6/2006 Consumer United States
Primary
Secondary
Concomitant
Radiation Skin Injury Other Serious 69 Female 132 lb 2/7/2006 Physician Germany
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 11/1/2005 54 Female 2/3/2006 Physician Spain
Primary
Concomitant
Wound Hospitalization 2/10/2006 Physician Germany
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 48 Female 208 lb 2/23/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 12/11/2001 52 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 Female 2/24/2006 Lawyer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 8/1/2003 63 Female 112 lb 2/28/2006 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/28/2002 78 Female 3/2/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Disability 1/1/2005 Female 3/17/2006 Physician Australia
Primary
Concomitant
Neuropathy Other Serious 1/1/2006 47 Female 3/10/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 10/1/2004 72 Female 115 lb 4/10/2006 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 4/18/2003 42 Female 111 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Groin Pain 11/8/2005 78 Female 4/11/2006 Consumer United States
Primary
Concomitant
Wound Debridement Other Serious 8/1/2002 48 Female 208 lb 4/12/2006 United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 1/1/2002 53 Female 4/19/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2003 63 Female 112 lb 5/5/2006 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 4/18/2003 42 Female 111 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Tooth Extraction Hospitalization 4/1/2005 25 Female 132 lb 5/5/2006 France
Primary
Secondary
Concomitant
Wound Debridement Other Serious 12/11/2001 52 Female 5/6/2006 United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Disability 12/1/2005 58 Female 5/3/2006 Physician Spain
Primary
Concomitant
Paraesthesia Disability 2/1/2006 56 Female 5/4/2006 Physician Spain
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 5/9/2006 Physician Brazil
Primary
Concomitant
Ejection Fraction Decreased Other Serious 10/20/2005 36 Female 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Cardiopulmonary Failure Other Serious 5/19/2005 35 Female 123 lb 5/23/2006 Physician France
Primary
Secondary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 5/22/2006 Physician Spain
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Other Serious 6/26/2001 73 Female 126 lb 6/2/2006 Lawyer United States
Primary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 6/2/2006 Physician Spain
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2005 Female 6/16/2006 Other Health Professional Turkey
Primary
Concomitant
Wound Hospitalization 6/14/2006 Physician Germany
Primary
Concomitant
Visual Acuity Reduced Disability 6/1/2005 57 Female 7/11/2006 Physician Spain
Primary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 7/13/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Increased Other Serious 6/9/2005 59 Female 7/24/2006 United States
Primary
Concomitant
Vomiting Hospitalization 3/20/2006 46 Female 137 lb 7/27/2006 Physician France
Primary
Concomitant
Tooth Infection Other Serious 6/20/2006 Female 7/18/2006 Physician United States
Primary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Ascites Hospitalization 6/21/2006 40 Female 8/8/2006 France
Primary
Secondary
Tooth Fracture Other Serious 2/24/2006 29 Female 8/14/2006 United States
Primary
Concomitant
Tooth Fracture Other Serious 2/24/2006 29 Female 8/14/2006 United States
Primary
Concomitant
Osteosclerosis Other Serious 6/20/2006 55 Female 8/18/2006 Physician United States
Primary
Concomitant
Surgery Hospitalization 6/1/2005 Female 128 lb 8/25/2006 Physician France
Primary
Concomitant
Surgery Hospitalization 9/1/2005 Female 117 lb 8/25/2006 Physician France
Primary
Concomitant
Ulcer Other Serious 1/1/2002 39 Female 8/31/2006 United States
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 10/20/2005 36 Female 6/6/2006 Physician United States
Primary
Secondary
Concomitant
Pleural Effusion Life Threatening 10/23/2005 38 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Pleural Effusion Hospitalization 57 6/6/2006 Other Health Professional United States
Primary
Concomitant
Hypersensitivity Required Intervention 6/10/2005 40 Female 6/6/2006 Other Health Professional United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 7/14/2005 68 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Osteonecrosis Other Serious 9/6/2006 76 Female 132 lb 9/30/2006 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2006 25 Female 9/29/2006 Physician Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/29/2004 54 Female 10/4/2006 United States
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Ulcer Other Serious 1/1/2002 39 Female 10/11/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/1/2006 25 Female 10/14/2006 Physician Japan
Primary
Concomitant
Dysphonia Hospitalization 8/18/2006 62 Female 10/16/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 7/1/2005 65 Female 134 lb 10/27/2006 Physician Brazil
Primary
Concomitant
Respiratory Failure Hospitalization 8/18/2006 59 Female 161 lb 10/28/2006 Physician Germany
Primary
Concomitant
Tooth Abscess Death 5/9/2006 43 Female 148 lb 11/6/2006 Physician Germany
Primary
Secondary
Concomitant
Wound Debridement Other Serious 7/1/2005 65 Female 134 lb 11/7/2006 Physician Brazil
Primary
Concomitant
Pyrexia Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Periodontitis Disability 1/1/2004 50 Female 11/15/2006 Switzerland
Primary
Concomitant
Restlessness Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/13/2006 56 Female 190 lb 11/18/2006 Other Health Professional Brazil
Primary
Concomitant
Wound Debridement Other Serious 11/1/2005 67 Female 134 lb 11/18/2006 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 11/20/2006 Lawyer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 11/21/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 11/20/2006 United States
Primary
Secondary
Concomitant
Gingival Pain 9/1/2006 25 Female 12/6/2006 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2006 41 Female 137 lb 12/8/2006 United Kingdom
Primary
Concomitant
Wound Debridement Hospitalization 4/1/2006 69 Female 12/16/2006 France
Primary
Secondary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 11/29/2004 54 Female 12/28/2006 United States
Primary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 1/8/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 8/1/2003 63 Female 112 lb 1/15/2007 United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 12/15/2006 Female 1/23/2007 Physician Japan
Primary
Concomitant
Dyspnoea Required Intervention 7/7/2005 48 Female 226 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Sinus Disorder Hospitalization 1/1/2004 48 Female 1/27/2007 France
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 37 Female 1/27/2007 France
Primary
Concomitant
Osteonecrosis Other Serious 9/6/2006 76 Female 132 lb 1/31/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 12/1/2006 65 Female 2/3/2007 Physician France
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/6/2007 Lawyer United States
Primary
Secondary
Concomitant
Impaired Healing Other Serious 1/5/2007 60 Female 2/6/2007 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/7/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 9/6/2006 76 Female 132 lb 2/12/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/14/2007 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2003 42 Female 111 lb 2/16/2007 Lawyer United States
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 2/16/2007 United States
Primary
Secondary
Concomitant
Vertigo 8/28/2005 58 Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Purulent Discharge Other Serious Female 3/7/2007 Physician Belgium
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious Female 3/1/2007 Physician Greece
Primary
Secondary
Concomitant
Toothache Other Serious 8/2/2006 55 Female 189 lb 3/14/2007 United States
Primary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Purulent Discharge Other Serious Female 3/15/2007 Physician Belgium
Primary
Concomitant
Loss Of Consciousness Death 2/8/2007 61 Female 106 lb 3/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 1/1/2002 63 Female 112 lb 3/21/2007 United States
Primary
Secondary
Concomitant
Vertigo Other Serious 7/1/2001 59 Female 11/6/2006 Consumer United States
Primary
Secondary
Concomitant
Surgery Other Serious 64 Female 3/30/2007 Other Health Professional Brazil
Primary
Concomitant
Wheezing Other Serious 3/25/1997 70 Female 126 lb 4/3/2007 Physician United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious Female 4/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 127 lb 4/11/2007 United States
Primary
Concomitant
Tooth Abscess Other Serious 2/1/2007 Female 4/13/2007 Other Health Professional United States
Primary
Concomitant
Tooth Extraction Other Serious 1/11/2007 58 Female 170 lb 4/17/2007 Physician Japan
Primary
Concomitant
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 12/18/2006 70 Female 5/5/2007 Japan
Primary
Secondary
Concomitant
Periodontitis Hospitalization 12/18/2006 70 Female 5/13/2007 Japan
Primary
Secondary
Concomitant
Tooth Extraction Disability 1/1/2005 Female 5/30/2007 Physician Australia
Primary
Concomitant
Vomiting Other Serious 4/18/2003 5/30/2007 Lawyer United States
Primary
Concomitant
Osteonecrosis Other Serious 6/13/2006 55 Female 3/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Hospitalization 3/1/2007 66 Female 167 lb 6/6/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 6/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Swelling Other Serious 11/1/2006 Female 6/15/2007 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 6/1/2006 42 Female 125 lb 6/19/2007 United Kingdom
Primary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 Female 6/19/2007 Physician United States
Primary
Secondary
Wound Debridement Hospitalization 11/1/2004 52 Female 6/29/2007 France
Primary
Concomitant
Deafness Other Serious 6/1/2007 60 Female 7/2/2007 Consumer United Kingdom
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 3/20/2007 Female 7/3/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
X-ray Abnormal Other Serious 2/5/2007 60 Female 7/4/2007 Physician Japan
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2007 45 Female 7/6/2007 Physician Sweden
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2007 45 Female 7/6/2007 Physician Sweden
Primary
Concomitant
Pruritus 52 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 49 Female 138 lb 7/6/2007 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper 5/14/2007 70 Female 7/6/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 45 Female 7/16/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Deafness Other Serious 6/1/2007 60 Female 7/17/2007 Consumer United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 45 Female 7/18/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 45 Female 7/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 45 Female 7/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Poor Personal Hygiene Other Serious 5/8/2007 58 Female 8/8/2007 Physician Japan
Primary
Secondary
Concomitant
Pain In Jaw Other Serious 5/10/2007 46 Female 119 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Toothache Other Serious 4/24/2006 71 Female 115 lb 8/10/2007 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 45 Female 8/17/2007 Other Health Professional Sweden
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 45 Female 8/17/2007
Primary
Secondary
Concomitant
X-ray Other Serious 12/1/2006 67 Female 119 lb 8/18/2007 Physician Lebanon
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/1/2007 59 Female 8/31/2007 Physician Japan
Primary
Concomitant
Sequestrectomy Other Serious 5/10/2007 46 Female 119 lb 9/1/2007 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 12/1/2005 75 Female 9/6/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/15/2007 75 Female 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant

Drug Data