Herceptin combined with Xeloda

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Jaundice Other Serious 57 Female 1/11/2006 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 1/18/2006 Physician Japan
Primary
Concomitant
Pulmonary Embolism Required Intervention 2/15/2006 Female 155 lb 2/16/2006 United States
Primary
Secondary
Pulmonary Oedema Death 7/19/2005 75 Female 3/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Metastatic Neoplasm Death 12/22/2005 57 Female 181 lb 3/23/2006 Physician United States
Primary
Concomitant
Metastatic Neoplasm Hospitalization 12/22/2005 57 Female 181 lb 4/20/2006 Physician United States
Primary
Concomitant
Swelling Face Hospitalization 3/30/2006 76 Female 90 lb 5/25/2006 Physician Japan
Primary
Concomitant
Purpura Hospitalization 3/20/2006 48 Female 5/26/2006 Consumer France
Primary
Secondary
Pulmonary Oedema Death Female 5/30/2006 Physician Germany
Primary
Concomitant
Purpura Hospitalization 3/20/2006 Female 6/2/2006 Other Health Professional France
Primary
Secondary
Pulmonary Oedema Death 5/9/2006 43 Female 148 lb 6/13/2006 Physician Germany
Primary
Secondary
Concomitant
Disease Progression Hospitalization 57 Female 6/30/2006 Other Health Professional United States
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 12/1/2005 58 Female 126 lb 6/30/2006 United States
Primary
Concomitant
Haemolytic Anaemia Hospitalization Female 7/25/2006 Physician France
Primary
Secondary
Vomiting Hospitalization 3/20/2006 46 Female 137 lb 7/27/2006 Physician France
Primary
Concomitant
Haemolytic Anaemia Hospitalization Female 7/28/2006 Physician France
Primary
Secondary
Surgery Hospitalization 6/1/2005 Female 128 lb 8/25/2006 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 7/8/2004 50 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2006 62 Female 9/21/2006 Physician Japan
Primary
Concomitant
Pericarditis Other Serious 61 Female 9/21/2006 Physician France
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Other Serious 59 Female 10/16/2006 Other Health Professional United States
Primary
Concomitant
Tooth Abscess Death 5/9/2006 43 Female 148 lb 11/6/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Pericarditis Other Serious 61 Female 132 lb 11/8/2006 Physician France
Primary
Concomitant
Restlessness Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Nerve Injury Other Serious Female 12/7/2006 Consumer Germany
Primary
Secondary
Ventricular Dysfunction Hospitalization 8/1/2006 50 Female 112 lb 11/29/2006 Consumer Spain
Primary
Secondary
Mitral Valve Incompetence Hospitalization 8/1/2006 50 Female 112 lb 12/8/2006 Consumer United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 8/1/2006 50 Female 112 lb 12/8/2006 Consumer United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 8/1/2006 50 Female 112 lb 12/13/2006 Consumer United States
Primary
Secondary
Optic Nerve Injury Other Serious Female 12/15/2006 Germany
Primary
Secondary
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/29/2005 71 Female 154 lb 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Sinus Disorder Hospitalization 1/1/2004 48 Female 1/27/2007 France
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2003 62 Female 1/26/2007 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 7/29/2005 71 Female 154 lb 1/26/2007 Physician Japan
Primary
Secondary
Concomitant
Optic Nerve Injury Other Serious Female 1/27/2007 Germany
Primary
Secondary
Pericarditis Other Serious 61 Female 132 lb 1/27/2007 Physician France
Primary
Concomitant
Dermatomyositis Disability 10/1/2006 Female 2/20/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 2/23/2007 Japan
Primary
Concomitant
Vomiting Life Threatening 2/18/2007 56 Female 3/2/2007 Physician Finland
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 3/8/2007 Japan
Primary
Concomitant
Toothache Other Serious 8/2/2006 55 Female 189 lb 3/14/2007 United States
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2003 63 Female 3/15/2007 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/13/2007 79 Female 4/4/2007 Physician Germany
Primary
Secondary
Concomitant
Dermatomyositis Disability 10/1/2006 Female 4/9/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 79 Female 6/4/2007 Physician Germany
Primary
Secondary
Concomitant
Diarrhoea Hospitalization 6/2/2005 49 Female 188 lb 6/29/2007 Physician United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/6/2007 Japan
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2007 45 Female 7/6/2007 Physician Sweden
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2007 45 Female 7/6/2007 Physician Sweden
Primary
Concomitant
Diarrhoea 4/1/2007 34 Female 7/6/2007 Consumer United States
Primary
Concomitant
Mouth Ulceration 47 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 49 Female 138 lb 7/6/2007 Other Health Professional United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/11/2007 Japan
Primary
Concomitant
Osteonecrosis Other Serious 45 Female 7/16/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 45 Female 7/18/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 45 Female 7/18/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 45 Female 7/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/19/2007 Female 7/25/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/19/2007 Female 198 lb 8/9/2007 Physician United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 5/10/2007 46 Female 119 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 45 Female 8/17/2007 Other Health Professional Sweden
Primary
Concomitant
Osteonecrosis Other Serious 3/1/2007 45 Female 8/17/2007
Primary
Secondary
Concomitant
X-ray Other Serious 12/1/2006 67 Female 119 lb 8/18/2007 Physician Lebanon
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Optic Nerve Disorder Other Serious Female 8/9/2007 Germany
Primary
Secondary
Sequestrectomy Other Serious 5/10/2007 46 Female 119 lb 9/1/2007 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 9/19/2007 Physician United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/13/2007 52 Female 139 lb 9/20/2007 Consumer China
Primary
Concomitant
Pulmonary Embolism Other Serious Female 10/4/2007 Physician United Kingdom
Primary
Secondary
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 10/8/2007 Physician United States
Primary
Secondary
Concomitant
Diarrhoea 6/24/2007 53 Female 10/11/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Life Threatening 71 Female 143 lb 10/12/2007 Other Health Professional United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 1/1/2007 Female 10/18/2007 Consumer United Kingdom
Primary
Secondary
Pulmonary Embolism Life Threatening 8/31/2007 Female 374 lb 10/26/2007 Physician United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 12/1/2003 46 Female 166 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Panniculitis 9/13/2005 Female 232 lb 10/30/2007 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 10/19/2007 Female 171 lb 10/25/2007 United States
Primary
Secondary
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 11/2/2007 Japan
Primary
Concomitant
Pyrexia Hospitalization 10/19/2007 Female 171 lb 11/2/2007 United States
Primary
Secondary
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 11/13/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/5/2007 Female 100 lb 11/13/2007 Physician United States
Primary
Secondary
Concomitant
Wound Treatment Hospitalization 6/1/2005 69 Female 128 lb 11/20/2007 Japan
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2007 60 Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious Female 11/23/2007 Physician Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 7/1/2007 Female 11/27/2007 Consumer Japan
Primary
Secondary
Hepatic Failure Death Female 12/5/2007 Physician Colombia
Primary
Concomitant
Osteonecrosis Other Serious Female 12/8/2007 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 10/1/2007 60 Female 12/8/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 12/11/2007 Physician
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/14/2007 Physician
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/1/2006 57 Female 161 lb 12/20/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 1/1/2007 54 Female 148 lb 12/22/2007 Physician Germany
Primary
Concomitant
Interstitial Lung Disease Hospitalization 7/1/2007 Female 12/27/2007 Consumer Japan
Primary
Secondary
Sepsis Other Serious 6/1/2005 47 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/29/2007 Physician
Primary
Secondary
Concomitant
Myocardial Infarction Death 11/18/2007 Female 1/2/2008 Consumer United Kingdom
Primary
Concomitant
Palpitations 59 Female 1/11/2008 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 1/18/2008 Consumer United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2006 57 Female 161 lb 1/18/2008 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 2/6/2008 Physician
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 61 Female 2/14/2008 Consumer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 2/28/2008 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 Female 197 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Mucosal Inflammation Hospitalization 1/25/2008 79 Female 3/14/2008 Italy
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/1/2007 Female 146 lb 3/20/2008 Consumer United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 11/2/2007 62 Female 4/2/2008 Consumer United States
Primary
Secondary
Concomitant
Pyogenic Granuloma Other Serious 61 Female 4/11/2008 Physician France
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 61 Female 4/17/2008 Physician United Kingdom
Primary
Secondary
Pyogenic Granuloma Other Serious 2/1/2007 Female 115 lb 5/1/2008 Physician France
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 3/1/2008 Female 115 lb 5/8/2008 Physician United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 1/11/2008 49 Female 266 lb 5/10/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/29/2005 Female 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious Female 6/3/2008 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Other Serious Female 6/3/2008 Consumer United Kingdom
Primary
Secondary
Blood Creatinine Increased Other Serious Female 6/3/2008 Consumer United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious Female 6/3/2008 Consumer United Kingdom
Primary
Secondary
Pneumonitis Other Serious 9/19/2007 72 Female 141 lb 3/27/2008 Physician United States
Primary
Concomitant
Muscular Weakness Other Serious 70 Female 6/11/2008 Consumer United Kingdom
Primary
Concomitant
Vasculitis Other Serious 3/27/2008 Female 6/12/2008 Physician France
Primary
Secondary
Vasculitis Other Serious Female 6/17/2008 Other Health Professional France
Primary
Secondary
Concomitant
Paralysis Other Serious 70 Female 6/24/2008 Consumer United Kingdom
Primary
Concomitant
Sepsis Death 3/1/2008 Female 7/1/2008 Physician Germany
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 4/1/2008 58 Female 6/29/2008 Pharmacist United States
Primary
Concomitant
Metastasis Death 6/14/2008 Female 7/10/2008 Consumer Costa Rica
Primary
Secondary
Sepsis Death 3/1/2008 Female 7/11/2008 Physician Germany
Primary
Concomitant
Cardiac Tamponade Other Serious Female 7/15/2008 Physician Japan
Primary
Secondary
Stomatitis Hospitalization 10/11/2004 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Headache Hospitalization 7/2/2008 37 Female 7/18/2008 Consumer United States
Primary
Concomitant
Vasculitis Other Serious 3/27/2008 Female 7/21/2008 Physician France
Primary
Secondary
Metastases To Lung Death 63 Female 7/30/2008 Physician Egypt
Primary
Secondary
Concomitant
Pancytopenia Death 3/21/2008 Female 183 lb 7/30/2008 Consumer United Kingdom
Primary
Concomitant
Vasculitis Other Serious Female 7/30/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vasospasm Other Serious 10/16/1995 Female 167 lb 9/10/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 9/23/2008 United States
Primary
Secondary
Concomitant
Blood Amylase Increased Other Serious Female 10/2/2008 Consumer Japan
Primary
Secondary
Concomitant
Disease Progression Death 35 Female 108 lb 10/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Lacrimation Increased 2/19/2008 70 Female 164 lb 11/11/2008 Pharmacist United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 10/1/2006 Female 12/10/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 12/19/2008 United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 1/1/2008 Female 154 lb 3/30/2009 Consumer Canada
Primary
Secondary
Concomitant

Drug Data