Herceptin combined with Vinorelbine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pain In Jaw Other Serious 11/1/2005 54 Female 2/3/2006 Physician Spain
Primary
Concomitant
Therapy Non-responder Other Serious 3/1/2006 54 Female 4/18/2006 Physician United States
Primary
Concomitant
Paraesthesia Disability 3/1/2006 56 Female 7/13/2006 Physician Spain
Primary
Concomitant
Tooth Infection Other Serious 6/20/2006 Female 7/18/2006 Physician United States
Primary
Concomitant
Osteosclerosis Other Serious 6/20/2006 55 Female 8/18/2006 Physician United States
Primary
Concomitant
Neck Mass Other Serious 1/1/2005 71 Female 6/6/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 8/18/2006 59 Female 161 lb 10/28/2006 Physician Germany
Primary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious 5/1/2003 56 Female 2/12/2007 Italy
Primary
Concomitant
Ejection Fraction Decreased Other Serious 1/16/2007 70 Female 2/22/2007 Physician Germany
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 4/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Dermatomyositis Disability 10/1/2006 Female 4/9/2007 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious Female 4/9/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 12/1/2006 37 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/14/2007 50 Female 110 lb 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 6/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious Female 6/14/2007 Consumer United Kingdom
Primary
Secondary
Pancreatitis Other Serious Female 11/13/2007 Consumer United Kingdom
Primary
Secondary
Blood Bilirubin Increased Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Gastrointestinal Toxicity Other Serious 1/1/2003 58 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 1/18/2008 Consumer United Kingdom
Primary
Concomitant
Vaginal Haemorrhage Other Serious Female 1/23/2008 Other Health Professional Germany
Primary
Concomitant
Transaminases Increased Other Serious Female 1/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Vaginal Haemorrhage Other Serious Female 2/15/2008 Other Health Professional Germany
Primary
Concomitant
Vocal Cord Paralysis Other Serious Female 2/22/2008 Physician United Kingdom
Primary
Secondary
Ventricular Extrasystoles Other Serious 12/1/2007 58 Female 2/28/2008 Consumer United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 4/9/2008 86 4/24/2008 Consumer United Kingdom
Primary
Concomitant
Renal Impairment Hospitalization 4/9/2008 Female 5/15/2008 Consumer United Kingdom
Primary
Concomitant
Tooth Loss Other Serious 1/1/2006 Female 11/21/2008 Physician Denmark
Primary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Blood Bilirubin Increased Other Serious 12/19/2008 Physician United Kingdom
Primary
Secondary
Renal Impairment Hospitalization 4/9/2008 Female 12/29/2008 Other Health Professional New Zealand
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 1/5/2009 Female 183 lb 1/12/2009 Consumer United States
Primary
Concomitant
Adrenal Insufficiency Hospitalization 1/5/2009 Female 183 lb 1/20/2009 Consumer United States
Primary
Concomitant
Cystitis Haemorrhagic Other Serious 2/8/2009 Female 3/6/2009 Consumer United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 1/1/2008 36 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious Female 5/19/2009 United Kingdom
Primary
Secondary
Metastases To Liver Other Serious 36 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pyrexia Hospitalization 4/26/2009 Female 227 lb 6/10/2009 Physician Belgium
Primary
Secondary
Thrombocytopenia Other Serious 6/9/2009 Physician United Kingdom
Primary
Secondary
Pyrexia Hospitalization 4/26/2009 Female 227 lb 7/6/2009 Physician Belgium
Primary
Secondary
White Blood Cell Count Other Serious Female 7/7/2009 Physician United Kingdom
Primary
Secondary
Sepsis Life Threatening Female 7/10/2009 Consumer New Zealand
Primary
Concomitant
Stomatitis Other Serious Female 10/6/2009 Physician United Kingdom
Primary
Secondary
Tooth Abscess Other Serious 2/26/2008 Female 10/7/2009 Physician Italy
Primary
Concomitant
Tooth Abscess Other Serious 2/26/2008 Female 10/23/2009 Other Health Professional Italy
Primary
Concomitant
Haemolysis Other Serious 10/14/2009 62 Female 10/28/2009 Physician United Kingdom
Primary
Concomitant
Haemolysis Life Threatening 10/13/2009 Female 11/18/2009 Physician United Kingdom
Primary
Secondary
Dermatomyositis Disability Female 1/20/2010 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 48 Female 2/25/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 48 Female 3/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 3/12/2002 Female 201 lb 3/31/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 4/17/2001 44 Female 201 lb 4/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 4/17/2001 44 Female 201 lb 5/4/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/5/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/17/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 5/26/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/3/2010 United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 36 Female 6/9/2010 Consumer Canada
Primary
Secondary
Concomitant
Hepatic Failure Death 12/15/2009 41 Female 243 lb 6/22/2010 Physician Egypt
Primary
Concomitant
Metastases To Central Nervous System Other Serious Female 6/28/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Failure Death 12/15/2009 41 Female 243 lb 6/30/2010 Physician Egypt
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/30/2010 United States
Primary
Secondary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 9/3/2010 United States
Primary
Secondary
Concomitant
Monoplegia Hospitalization 9/30/2010 65 Female 112 lb 11/19/2010 Physician Japan
Primary
Secondary
Concomitant
Disease Progression Death Female 11/29/2010 Other Health Professional Australia
Primary
Secondary
Monoplegia Hospitalization 9/10/2010 65 Female 112 lb 12/2/2010 Physician Japan
Primary
Secondary
Concomitant
Wound Complication 1/21/2010 59 Female 115 lb 12/14/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Periodontitis 1/21/2010 59 Female 115 lb 12/15/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypokalaemia Life Threatening 9/6/2009 70 Female 110 lb 12/23/2010 Physician Germany
Primary
Concomitant
Hypokalaemia Life Threatening 9/6/2010 71 Female 110 lb 12/28/2010 Physician Germany
Primary
Concomitant
Pyrexia Hospitalization 12/27/2010 53 Female 1/31/2011 Physician Austria
Primary
Concomitant
Febrile Neutropenia Hospitalization 12/28/2010 52 Female 128 lb 1/31/2011 Physician Hong Kong
Primary
Secondary
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 11/1/2010 64 Female 2/4/2011 Other Health Professional Poland
Primary
Secondary
Concomitant
Cholelithiasis Hospitalization 6/25/2009 52 Female 142 lb 2/12/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Extravasation Other Serious Female 2/24/2011 Other Health Professional France
Primary
Secondary
Osteonecrosis Other Serious 1/21/2010 59 Female 115 lb 7/21/2011 Physician Japan
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 70 Female 10/19/2011 Physician Japan
Primary
Secondary
Concomitant
Intracardiac Thrombus Other Serious 44 Female 10/19/2011 Physician Japan
Primary
Concomitant
Breast Cancer Recurrent Hospitalization 50 Female 10/19/2011 Japan
Primary
Concomitant
Ejection Fraction Decreased Other Serious 47 Female 10/20/2011 Consumer United States
Primary
Secondary
Concomitant
Hypotension Other Serious 47 Female 10/21/2011 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 70 Female 10/24/2011 Physician Japan
Primary
Secondary
Concomitant
Ulcer Other Serious 70 Female 12/12/2011 Japan
Primary
Secondary
Concomitant
Radiation Oesophagitis Other Serious Female 12/27/2011 Lawyer United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/5/2011 62 Female 1/17/2012 Other Health Professional Italy
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/1/2003 44 Female 152 lb 3/16/2012 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization 9/1/2009 49 Female 93 lb 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Death Death Female 187 lb 4/10/2012 United States
Primary
Secondary
Concomitant
Ascites Hospitalization 1/1/2003 44 Female 152 lb 4/13/2012 Physician United States
Primary
Secondary
Concomitant
Bone Loss Hospitalization 1/1/2003 44 Female 152 lb 5/30/2012 Consumer United States
Primary
Secondary
Concomitant
Haemoptysis Other Serious 1/1/2003 44 Female 152 lb 6/1/2012 Physician United States
Primary
Secondary
Concomitant
Dermatomyositis Other Serious Female 6/25/2012 Consumer United States
Primary
Secondary
Alanine Aminotransferase Increased Other Serious 5/21/2012 60 Female 154 lb 7/11/2012 Physician United States
Primary
Concomitant
Pulmonary Toxicity Death Female 7/24/2012 Physician Spain
Primary
Secondary
Respiratory Failure Hospitalization 3/5/2012 44 Female 163 lb 7/31/2012 Physician Spain
Primary
Secondary
Disease Recurrence Other Serious 1/1/2006 45 Female 8/3/2012 Physician Australia
Primary
Secondary
Concomitant
Paronychia Other Serious 1/1/2003 44 Female 152 lb 8/3/2012 Physician United States
Primary
Secondary
Concomitant
Fall Other Serious Female 8/7/2012 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 1/1/2003 44 Female 152 lb 8/10/2012 Lawyer United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 43 148 lb 8/14/2012 Physician Australia
Primary
Secondary
Concomitant
Metastases To Breast Other Serious 7/1/2012 30 Female 128 lb 8/17/2012 Consumer China
Primary
Secondary
Concomitant
Drug Ineffective Other Serious Female 9/18/2012 Consumer Ru
Primary
Secondary
Concomitant
Vomiting Other Serious 5/2011 62 Female 117 lb 9/27/2012 Physician Be
Primary
Secondary
Death Death 9/28/2012 Physician Us
Primary
Concomitant
Enterocolitis Hospitalization 9/10/2012 60 Female 134 lb 3/6/2013 Physician Jp
Primary
Secondary
Disease Progression Other Serious Female 10/8/2012 Physician Ca
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 10/8/2012 Physician Au
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 143 lb 3/22/2013 Physician Au
Primary
Secondary
Concomitant
Rhinorrhoea Hospitalization 1/1/2006 48 Female 11/2/2012 Consumer Country Not Specified
Primary
Concomitant
Ejection Fraction Decreased Other Serious 11/8/2012 Other Health Professional Za
Primary
Concomitant
Disease Progression Other Serious Female 11/7/2012 Physician Dk
Primary
Secondary
Concomitant
Tenderness Other Serious Female 2/11/2013 Physician Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious Female 11/15/2012 Physician Dk
Primary
Secondary
Superior Vena Cava Syndrome Other Serious 7/2011 Female 1/24/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 57 Female 11/26/2012 Physician Dk
Primary
Secondary
Tenderness Other Serious 2010 Female 1/29/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious 10/26/2010 57 Female 1/29/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious Female 11/30/2012 Physician Dk
Primary
Secondary
Concomitant
Superior Vena Cava Syndrome Death 2010 64 Female 2/4/2013 Consumer Dk
Primary
Secondary
Concomitant
Tenderness Other Serious 2010 Female 2/17/2013 Physician Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 57 Female 11/26/2012 Physician Dk
Primary
Secondary
Vomiting Other Serious Female 132 lb 12/10/2012 Physician Be
Primary
Secondary
Disease Progression Other Serious 12/2011 38 Female 12/17/2012 Country Not Specified
Primary
Concomitant
Disease Progression Other Serious 59 Female 12/11/2012 Physician Dk
Primary
Secondary
Disease Progression Other Serious Male 12/31/2012 Physician Dk
Primary
Secondary
Metastases To Liver Other Serious 2006 Female 1/3/2013 Physician Dk
Primary
Secondary
Rash Other Serious 3/19/2010 44 Female 3/12/2013 Consumer Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious Male 1/8/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious Female 1/8/2013 Physician Au
Primary
Secondary
Concomitant
Disease Progression Other Serious 49 Female 132 lb 1/11/2013 Physician Be
Primary
Secondary
Metastases To Skin Other Serious 10/2005 Female 1/9/2013 Physician Dk
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 2006 Female 2/4/2013 Other Health Professional Dk
Primary
Secondary
Metastases To Liver Other Serious 2006 Female 1/30/2013 Physician Dk
Primary
Secondary
Rash Other Serious Female 1/29/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious Male 1/18/2013 Physician Dk
Primary
Secondary
Tenderness Other Serious Female 2/1/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Second Primary Malignancy Other Serious 10/2005 64 Female 1/23/2013 Physician Dk
Primary
Secondary
Concomitant
Renal Function Test Abnormal Other Serious 58 Female 1/25/2013 Physician Pl
Primary
Secondary
Concomitant
Rash Other Serious Female 1/25/2013 Physician Dk
Primary
Secondary
Tenderness Other Serious 2010 64 Female 2/14/2013 Physician Dk
Primary
Secondary
Concomitant
Rash Other Serious 2/2008 Female 3/14/2013 Physician Dk
Primary
Secondary
Concomitant
Metastases To Skin Other Serious 10/2005 Female 1/21/2013 Physician Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious 10/26/2010 Female 2/8/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 1/25/2013 Female 2/6/2013 Physician Dk
Primary
Secondary
Rash Other Serious Female 1/22/2013 Physician Dk
Primary
Secondary
Metastases To The Mediastinum Other Serious 7/29/2009 Female 1/31/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 3/2008 44 Female 3/7/2013 Physician At
Primary
Secondary
Concomitant
Metastases To Liver Other Serious 1/4/2012 77 Female 129 lb 1/28/2013 Physician Be
Primary
Secondary
Disease Progression Other Serious 1/25/2013 56 Female 2/15/2013 Physician Dk
Primary
Secondary
Rash Other Serious Female 1/16/2013 Other Health Professional Dk
Primary
Secondary

Drug Data