Herceptin combined with Tykerb

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Diarrhoea Other Serious 4/9/2007 45 Female 4/24/2007 Consumer United States
Primary
Concomitant
Tachypnoea Other Serious 4/9/2007 45 Female 5/10/2007 Consumer United States
Primary
Concomitant
Death Death 1/1/2007 Female 5/22/2007 Other Health Professional United States
Primary
Secondary
Rash Hospitalization 3/1/2007 66 Female 167 lb 6/6/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 5/15/2007 81 Female 6/11/2007 Consumer United States
Primary
Concomitant
Pruritus 52 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 4/1/2007 34 Female 7/6/2007 Consumer United States
Primary
Concomitant
Mouth Ulceration 47 Female 7/6/2007 Consumer United States
Primary
Concomitant
Lip Oedema 5/5/2007 52 Female 7/6/2007 Consumer United States
Primary
Concomitant
Fatigue 4/11/2007 55 Female 7/6/2007 Consumer United States
Primary
Concomitant
Sluggishness 4/26/2007 42 Female 7/6/2007 Consumer United States
Primary
Concomitant
Infrequent Bowel Movements 4/26/2007 63 Female 7/6/2007 Consumer United States
Primary
Concomitant
Weight Decreased 5/7/2007 34 Female 7/6/2007 Consumer United States
Primary
Concomitant
Paraesthesia 5/24/2007 47 Female 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 5/29/2007 66 Female 174 lb 7/6/2007 Consumer United States
Primary
Concomitant
Diarrhoea 49 Female 138 lb 7/6/2007 Other Health Professional United States
Primary
Concomitant
Vomiting 5/1/2007 47 Female 7/6/2007 Consumer United States
Primary
Secondary
Abdominal Pain Upper 5/14/2007 70 Female 7/6/2007 Consumer United States
Primary
Concomitant
Death Death 1/1/2007 35 Female 190 lb 7/20/2007 Other Health Professional United States
Primary
Secondary
Abdominal Pain Upper 5/14/2007 70 Female 10/11/2007 Consumer United States
Primary
Concomitant
Diarrhoea 6/24/2007 53 Female 10/11/2007 Consumer United States
Primary
Concomitant
Nausea 64 Female 10/11/2007 Consumer United States
Primary
Secondary
Vomiting 7/6/2007 49 Male 10/11/2007 Consumer United States
Primary
Concomitant
Rash 59 Female 10/11/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection 9/28/2007 54 Female 1/11/2008 Other Health Professional United States
Primary
Concomitant
Diarrhoea 11/2/2007 50 Female 1/11/2008 Consumer United States
Primary
Concomitant
Palpitations 59 Female 1/11/2008 Consumer United States
Primary
Concomitant
Stomach Discomfort 12/2/2007 45 Female 1/11/2008 Consumer United States
Primary
Concomitant
Pneumothorax Other Serious Female 1/30/2008 Consumer United States
Primary
Secondary
Vomiting Hospitalization 2/20/2008 Female 197 lb 2/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 11/2/2007 62 Female 4/2/2008 Consumer United States
Primary
Secondary
Concomitant
Stomach Discomfort 12/2/2007 45 Female 4/10/2008 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/11/2008 49 Female 266 lb 5/10/2008 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 63 Female 6/23/2008 Physician Egypt
Primary
Concomitant
White Blood Cell Count Decreased 4/1/2008 33 Female 7/3/2008 Physician United States
Primary
Concomitant
Skin Exfoliation 33 Female 7/3/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection 5/8/2008 43 Female 291 lb 7/3/2008 Consumer United States
Primary
Concomitant
Metastases To Lung Death 63 Female 7/30/2008 Physician Egypt
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 5/1/2008 56 Female 7/31/2008 Physician United States
Primary
Concomitant
Haemoglobin Decreased Other Serious 71 Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 9/26/2008 Female 183 lb 9/26/2008 Physician United States
Primary
Secondary
Concomitant
Retching 12/2/2007 45 Female 10/10/2008 Consumer United States
Primary
Concomitant
Rash 6/24/2008 66 Female 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 7/23/2008 46 Female 10/10/2008 Consumer United States
Primary
Secondary
Concomitant
Gastrointestinal Pain 8/1/2008 62 Female 10/10/2008 Consumer United States
Primary
Concomitant
Rash 8/15/2008 58 Female 162 lb 10/10/2008 Consumer United States
Primary
Concomitant
Rash Female 10/10/2008 Consumer United States
Primary
Concomitant
No Therapeutic Response Hospitalization 9/26/2008 Female 183 lb 10/9/2008 Physician United States
Primary
Secondary
Concomitant
Diarrhoea 9/10/2008 46 Female 1/6/2009 Consumer United States
Primary
Concomitant
Adverse Reaction 58 Female 1/6/2009 Consumer United States
Primary
Concomitant
Rash Female 1/6/2009 Consumer United States
Primary
Concomitant
Fatigue 9/25/2008 78 Female 1/6/2009 Consumer United States
Primary
Concomitant
Skin Chapped 9/22/2008 57 Female 1/6/2009 Consumer United States
Primary
Concomitant
Swollen Tongue 10/14/2008 64 Female 1/6/2009 Consumer United States
Primary
Concomitant
Therapeutic Response Unexpected 54 Female 1/6/2009 Consumer United States
Primary
Concomitant
Diarrhoea Other Serious Female 1/6/2009 Consumer United States
Primary
Concomitant
Rash 6/1/2008 66 Female 1/6/2009 Consumer United States
Primary
Concomitant
Diarrhoea 62 Female 1/6/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 12/1/2008 46 Female 2/23/2009 Consumer United States
Primary
Secondary
Concomitant
Rash 12/28/2008 61 Female 175 lb 4/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia 1/4/2009 61 Female 4/2/2009 Consumer United States
Primary
Concomitant
Vasodilatation 51 Female 4/2/2009 Consumer United States
Primary
Secondary
Concomitant
Fatigue 1/1/2009 57 Female 4/2/2009 Consumer United States
Primary
Concomitant
Diarrhoea 2/23/2009 49 Female 4/2/2009 Consumer United States
Primary
Concomitant
Scar 53 Female 4/2/2009 Consumer United States
Primary
Secondary
Concomitant
Wound 47 Female 4/2/2009 Consumer United States
Primary
Concomitant
Ocular Neoplasm Other Serious 34 Female 5/8/2009 Other Health Professional Greece
Primary
Secondary
Concomitant
Rash Other Serious 3/21/2009 49 Female 5/12/2009 Consumer United States
Primary
Concomitant
Diarrhoea 5/14/2009 Other Health Professional United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious Female 6/5/2009 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization Female 6/5/2009 Physician United States
Primary
Concomitant
Neoplasm Progression Other Serious Female 6/15/2009 Consumer United States
Primary
Secondary
Concomitant
Pyrexia 1/25/2009 61 Female 7/10/2009 Consumer United States
Primary
Concomitant
Rash 3/13/2009 49 Female 7/10/2009 Consumer United States
Primary
Concomitant
Urticaria 3/17/2009 62 Female 7/10/2009 Consumer United States
Primary
Concomitant
Pain In Extremity 2/23/2009 58 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting 5/2/2009 44 Female 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Haemorrhoids 5/21/2009 62 Female 7/10/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 59 Female 123 lb 7/17/2009 Physician India
Primary
Concomitant
Drug Ineffective Other Serious Female 7/23/2009 Consumer United States
Primary
Secondary
Concomitant
Lung Neoplasm Malignant Other Serious Female 7/29/2009 Consumer United States
Primary
Secondary
Concomitant
Nausea Hospitalization 7/7/2009 Female 8/12/2009 Physician Japan
Primary
Secondary
Concomitant
Rash Other Serious Female 8/18/2009 Consumer United States
Primary
Secondary
Breast Cancer Metastatic Life Threatening 7/28/2009 Female 168 lb 8/19/2009 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/6/2009 45 Female 8/26/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 8/6/2009 45 Female 130 lb 9/28/2009 Consumer United States
Primary
Concomitant
Skin Laceration 5/30/2009 46 Female 183 lb 9/24/2009 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased 5/30/2009 46 Female 9/24/2009 Consumer United States
Primary
Concomitant
Skin Exfoliation 3/1/2009 66 Female 9/24/2009 Consumer United States
Primary
Concomitant
Abdominal Pain Upper 6/28/2009 84 Female 9/24/2009 Consumer United States
Primary
Concomitant
Faecal Incontinence 6/26/2009 69 Female 9/24/2009 Consumer United States
Primary
Concomitant
Diarrhoea 7/7/2009 56 Female 9/24/2009 Consumer United States
Primary
Concomitant
Oedema Peripheral 7/1/2009 60 Female 9/24/2009 Consumer United States
Primary
Concomitant
Diarrhoea 8/20/2009 28 Female 9/24/2009 Consumer United States
Primary
Concomitant
Somnolence 8/28/2009 48 Female 9/24/2009 Consumer United States
Primary
Concomitant
Nausea 9/6/2009 66 Female 9/24/2009 Consumer United States
Primary
Concomitant
Rash Other Serious 6/1/2009 65 Female 10/21/2009 Physician Brazil
Primary
Secondary
Concomitant
Muscular Weakness Required Intervention 10/6/2009 Female 124 lb 10/19/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/24/2009 63 Female 10/30/2009 Consumer United States
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 49 Female 10/30/2009 Physician Australia
Primary
Secondary
Concomitant
Rash Other Serious 6/1/2009 65 Female 11/9/2009 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/8/2009 63 Female 11/9/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/24/2009 63 Female 11/12/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious Female 11/20/2009 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/28/2008 Female 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 1/1/2009 38 Female 12/2/2009 Consumer United States
Primary
Concomitant
Skin Laceration Hospitalization 11/9/2009 51 Female 12/3/2009 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 9/15/2009 44 Female 164 lb 12/21/2009 Physician United States
Primary
Concomitant
Skin Exfoliation 3/1/2009 66 Female 1/8/2010 Consumer United States
Primary
Concomitant
Skin Chapped 1/1/2008 62 Female 1/8/2010 Consumer United States
Primary
Concomitant
Weight Decreased 11/5/2009 57 Female 1/8/2010 Consumer United States
Primary
Concomitant
Rash 10/1/2009 60 Female 1/8/2010 Other Health Professional United States
Primary
Secondary
Ill-defined Disorder 11/9/2009 61 Female 1/8/2010 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious Female 125 lb 1/21/2010 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Other Serious Female 1/28/2010 Consumer United States
Primary
Concomitant
Wheelchair User Other Serious 1/1/2009 66 Female 125 lb 2/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Monoplegia Other Serious 9/1/2008 36 Female 2/4/2010 Physician Japan
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious Female 125 lb 2/5/2010 Other Health Professional United States
Primary
Secondary
Monoplegia Hospitalization 9/1/2008 36 Female 2/11/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/1/2009 Female 2/11/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/16/2010 60 Female 2/18/2010 Consumer United States
Primary
Concomitant
Neutropenia Other Serious 1/1/2009 68 Female 106 lb 2/18/2010 Other Health Professional United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 57 Female 2/19/2010 Consumer Canada
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 6/25/2005 Female 2/26/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3/1/2009 Female 2/26/2010 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 6/27/2009 Female 89 lb 3/4/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 5/1/2009 Female 3/8/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 38 Female 153 lb 3/9/2010 Consumer United States
Primary
Concomitant
Disease Progression Other Serious 1/1/2008 37 Female 3/11/2010 Consumer Canada
Primary
Secondary
Rash Other Serious Female 3/11/2010 Physician United States
Primary
Secondary
Weight Decreased Other Serious 6/25/2005 Female 3/11/2010 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 11/29/2007 Female 3/12/2010 Other Health Professional United States
Primary
Concomitant
Disease Progression Death 59 Female 3/18/2010 Consumer United States
Primary
Concomitant
Skin Discolouration Hospitalization 38 Female 3/19/2010 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2005 Female 3/25/2010 Physician United States
Primary
Secondary
Concomitant
Disease Progression Other Serious 57 Female 3/30/2010 Other Health Professional France
Primary
Secondary
Concomitant
Treatment Failure Other Serious 1/1/2008 Female 3/30/2010 Physician United States
Primary
Secondary
Concomitant
Haematochezia Other Serious 66 Female 141 lb 3/31/2010 Consumer United States
Primary
Concomitant
Stomatitis 58 Female 4/9/2010 Consumer United States
Primary
Concomitant
Rash 56 Female 4/9/2010 Consumer United States
Primary
Concomitant
Nausea 59 Female 4/9/2010 Consumer United States
Primary
Concomitant
Stomatitis 34 Female 4/9/2010 Consumer United States
Primary
Concomitant
Respiratory Tract Congestion 58 Female 4/9/2010 Consumer United States
Primary
Concomitant
Retching 67 Female 4/9/2010 Consumer United States
Primary
Concomitant
Rash 49 Female 4/9/2010 Consumer United States
Primary
Concomitant
Pollakiuria 54 Female 4/9/2010 Consumer United States
Primary
Concomitant
Sinusitis 49 Female 175 lb 4/9/2010 Consumer United States
Primary
Secondary
Diarrhoea 61 Female 4/9/2010 Consumer United States
Primary
Secondary
Concomitant
Nausea 51 Female 4/9/2010 Consumer United States
Primary
Concomitant
Vomiting 57 Female 4/9/2010 Consumer United States
Primary
Concomitant

Drug Data