Herceptin combined with Tamoxifen

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 5/31/2006 United States
Primary
Secondary
Concomitant
Mitral Valve Incompetence Hospitalization Female 4/16/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 79 Female 6/4/2007 Physician Germany
Primary
Secondary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 6/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 9/19/2007 Physician United States
Primary
Concomitant
Stomach Discomfort 12/2/2007 45 Female 1/11/2008 Consumer United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 1/16/2008 Physician United States
Primary
Concomitant
Vasculitis Other Serious 10/1/2007 Female 150 lb 1/23/2008 Physician United Kingdom
Primary
Secondary
Ventricular Extrasystoles Other Serious 11/24/2007 60 Female 1/30/2008 Physician United Kingdom
Primary
Concomitant
Toothache Other Serious 4/1/2000 66 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Toothache Other Serious 4/1/2000 66 Female 167 lb 4/22/2008 United States
Primary
Secondary
Concomitant
Premature Rupture Of Membranes Other Serious 1/1/2007 28 Female 11/3/2008 Consumer New Zealand
Primary
Concomitant
Vision Blurred Other Serious 1/1/2001 Female 152 lb 11/28/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 12/19/2008 United States
Primary
Secondary
Concomitant
Respiratory Arrest Death Male 4 lb 8/4/2009 Other Health Professional New Zealand
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Congenital Anomaly Female 8/4/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious Male 4 lb 8/6/2009 Other Health Professional New Zealand
Primary
Concomitant
Respiratory Failure Other Serious Male 11/9/2009 Physician Germany
Primary
Concomitant
Tumour Invasion Other Serious 11/30/2005 48 Female 6/15/2010 United States
Primary
Concomitant
Spinal Osteoarthritis Other Serious 2/13/2001 62 Female 134 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Iridocyclitis Other Serious Female 137 lb 6/18/2010 Physician Germany
Primary
Concomitant
Hepatic Failure Death 12/15/2009 41 Female 243 lb 6/22/2010 Physician Egypt
Primary
Concomitant
Vomiting Other Serious 2/13/2001 62 Female 134 lb 6/24/2010 United States
Primary
Secondary
Concomitant
Swelling Disability 11/25/2009 48 Female 164 lb 6/30/2010 Consumer United Kingdom
Primary
Concomitant
Hepatic Failure Death 12/15/2009 41 Female 243 lb 6/30/2010 Physician Egypt
Primary
Concomitant
Wound Dehiscence Other Serious 10/9/2001 44 Female 201 lb 6/30/2010 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 2/1/2010 47 Female 7/14/2010 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 2/13/2001 62 Female 134 lb 7/14/2010 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 3/1/2002 50 Male 7/15/2010 United States
Primary
Concomitant
Vomiting Other Serious 4/15/2003 55 Female 7/16/2010 United States
Primary
Concomitant
Wheezing Other Serious 61 Female 150 lb 7/20/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/22/2010 United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 7/23/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/25/2005 55 Female 7/23/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious Female 188 lb 8/5/2010 Physician United States
Primary
Secondary
Concomitant
Wound Infection Staphylococcal Other Serious 1/1/2003 42 Female 170 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious Female 11/10/2010 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2002 50 Female 188 lb 11/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiomyopathy Other Serious 4/15/2003 55 Female 1/19/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Other Serious 5/1/2002 58 Female 1/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hot Flush Other Serious 8/1/2010 47 Female 119 lb 2/17/2011 Consumer Netherlands
Primary
Concomitant
Bruxism Other Serious 3/3/2000 41 Female 208 lb 3/17/2011 Physician United States
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 3/17/2011 Lawyer United States
Primary
Concomitant
Cataract Other Serious 6/29/2006 82 Female 4/20/2011 Physician United States
Primary
Concomitant
Aspiration Hospitalization 11/29/2004 53 Female 4/27/2011 Physician United States
Primary
Concomitant
Rash Papular 12/16/2010 25 Female 5/2/2011 Consumer United States
Primary
Concomitant
Occult Blood Positive Other Serious 3/3/2002 43 Female 208 lb 5/12/2011 Physician United States
Primary
Secondary
Concomitant
Vomiting 10/3/2011 42 Female 160 lb 10/9/2011 Consumer United States
Primary
Concomitant
Anhedonia Death Female 12/7/2011 Lawyer United States
Primary
Concomitant
Pancreatitis Hospitalization 7/20/2011 38 Female 163 lb 12/7/2011 Germany
Primary
Secondary
Concomitant
Gait Disturbance Other Serious Female 123 lb 12/15/2011 Lawyer United States
Primary
Secondary
Concomitant
Hypertension Other Serious Female 12/21/2011 Physician United States
Primary
Secondary
Concomitant
Wound Other Serious 10/21/2010 66 Female 10/10/2012 Consumer Us
Primary
Concomitant
Gastric Cancer Other Serious 1/2012 Female 134 lb 10/16/2012 Other Health Professional Jp
Primary
Secondary
Thyroiditis Subacute Other Serious 4/2012 44 Female 11/19/2012 Physician Es
Primary
Concomitant
Tremor Other Serious 5/16/2012 64 Female 133 lb 9/25/2012 Pharmacist Br
Primary
Concomitant
Disease Progression Other Serious Female 11/9/2012 Physician Us
Primary
Concomitant
Death Death Female 9/26/2012 Physician Us
Primary
Concomitant
Death Death 3/27/1999 85 Female 9/27/2012 Physician Us
Primary
Concomitant
Death Death 1/10/1999 39 Female 9/28/2012 Physician Us
Primary
Concomitant
Death Death Female 12/11/2012 Consumer Us
Primary
Concomitant
Neoplasm Other Serious Female 10/1/2012 Physician Us
Primary
Concomitant
Plantar Erythema Death Female 10/1/2012 Physician Us
Primary
Concomitant
Pyrexia Other Serious Female 10/1/2012 Physician Us
Primary
Concomitant
Wheezing Death Female 123 lb 10/1/2012 Physician Us
Primary
Concomitant
Paraplegia Other Serious Female 11/27/2012 Physician De
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 50 Female 10/30/2012 Physician Au
Primary
Secondary
Rash Pruritic Other Serious Female 11/5/2012 Physician Au
Primary
Secondary
Concomitant
Ejection Fraction Decreased Other Serious 9/27/2012 49 Female 126 lb 10/26/2012 Pharmacist Us
Primary
Concomitant
Drug Ineffective Other Serious 2/2011 68 Female 119 lb 11/20/2012 Physician Be
Primary
Secondary
Concomitant
Disease Progression Other Serious 1/2013 46 Female 109 lb 1/22/2013 Physician Be
Primary
Secondary
Disease Progression Other Serious Female 206 lb 2/28/2013 Pharmacist Ie
Primary
Concomitant
Treatment Failure Other Serious Female 5/9/2013 Physician Pl
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious Female 1/30/2013 Physician Pl
Primary
Secondary
Concomitant
Death Death Female 2/18/2013 Physician Es
Primary
Concomitant
Metastases To Bone Other Serious 12/22/2009 69 Female 8/21/2013 Physician At
Primary
Secondary
Concomitant
Subclavian Vein Thrombosis Hospitalization 1/28/2012 37 Female 3/22/2013 Consumer Us
Primary
Concomitant
Metastasis Other Serious 6/2009 30 Female 4/18/2013 Physician Au
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 6/21/2013 Physician Dk
Primary
Secondary
Concomitant
Vein Disorder Other Serious 2010 49 Female 145 lb 6/19/2013 Consumer Ca
Primary
Secondary
Concomitant
Skin Cancer Other Serious 4/2012 45 Female 5/23/2013 Consumer Dk
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 5/17/2013 Physician Dk
Primary
Secondary
Concomitant
Skin Cancer Other Serious Female 5/9/2013 Other Health Professional Dk
Primary
Secondary
Rash 6/13/2012 40 Female 5/10/2013 Consumer Us
Primary
Concomitant
Diarrhoea 1/14/2013 54 Female 146 lb 5/10/2013 Consumer Us
Primary
Concomitant
Metastases To Bone Other Serious Female 5/23/2013 Physician Au
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/2012 33 Female 137 lb 6/1/2013 Physician Pl
Primary
Concomitant
Metastatic Neoplasm Other Serious Female 5/20/2013 Physician Dk
Primary
Secondary
Stress Fracture Other Serious 60 Female 5/20/2013 Consumer Us
Primary
Concomitant
Neuropathy Peripheral Other Serious Female 5/21/2013 Other Health Professional Gb
Primary
Secondary
Skin Cancer Other Serious Female 5/21/2013 Other Health Professional Dk
Primary
Secondary
Neutropenia Required Intervention Female 5/17/2013 Other Health Professional Dk
Primary
Secondary
Pleural Effusion Other Serious 44 Female 7/18/2013 Physician Dk
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious 6/2011 69 Female 5/30/2013 Consumer Dk
Primary
Secondary
Pleural Effusion Other Serious Female 7/8/2013 Consumer Dk
Primary
Secondary
Concomitant
Off Label Use Other Serious 69 Female 6/3/2013 Physician Dk
Primary
Secondary
Vision Blurred Death 12/2012 75 Female 115 lb 6/3/2013 Consumer Mx
Primary
Concomitant
Pleural Effusion Other Serious Female 6/18/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious Female 6/3/2013 Other Health Professional Gb
Primary
Secondary
Pleural Effusion Other Serious 44 Female 7/9/2013 Physician Dk
Primary
Secondary
Concomitant
Metastatic Neoplasm Other Serious Female 6/3/2013 Physician Dk
Primary
Secondary
Metastatic Neoplasm Other Serious 69 Female 6/4/2013 Physician Dk
Primary
Secondary
Pancreatitis Acute Hospitalization 5/24/2013 38 Female 112 lb 7/23/2013 Physician Jp
Primary
Secondary
Concomitant
Pleural Effusion Other Serious Female 7/9/2013 Consumer Dk
Primary
Secondary
Concomitant
Tremor Other Serious Female 6/5/2013 Consumer Br
Primary
Secondary
Pleural Effusion Other Serious Female 7/15/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Neuropathy Peripheral Other Serious 52 Female 6/6/2013 Other Health Professional Gb
Primary
Secondary
Metastases To Liver Other Serious 69 Female 6/3/2013 Other Health Professional Dk
Primary
Secondary
Concomitant
Disease Progression Other Serious Female 6/11/2013 Consumer Br
Primary
Concomitant
Skin Cancer Other Serious 1/2013 45 Female 6/13/2013 Other Health Professional Dk
Primary
Secondary
Weight Increased Hospitalization Female 165 lb 6/18/2013 Consumer Mx
Primary
Secondary
Acute Febrile Neutrophilic Dermatosis Hospitalization Female 201 lb 7/22/2013 Pharmacist Gb
Primary
Secondary
Concomitant
Skin Lesion Other Serious 10/26/2009 36 Female 258 lb 7/18/2013 Physician Be
Primary
Secondary
Concomitant
Vision Blurred Other Serious 6/2012 44 Female 9/2/2013 Consumer Mx
Primary
Concomitant
Disease Progression Other Serious Female 9/11/2013 Physician Dk
Primary
Secondary
Disease Progression 31 Female 9/18/2013 Physician Dk
Primary
Secondary
Malignant Neoplasm Progression Other Serious Female 9/19/2013 Physician Dk
Primary
Secondary
Non-hodgkin's Lymphoma Hospitalization 2004 Female 8/15/2013 Physician Au
Primary
Secondary
Concomitant
Metastases To Lung Other Serious Female 9/18/2013 Other Health Professional Dk
Primary
Secondary
Ulcer Other Serious 2012 Female 8/16/2013 Physician Au
Primary
Secondary
Concomitant
Osteonecrosis Of Jaw Other Serious 36 Female 10/8/2013 Physician Us
Primary
Concomitant
Ovarian Cyst Other Serious 12/20/2012 35 Female 172 lb 8/19/2013 Consumer Cl
Primary
Secondary
Disease Progression Other Serious 31 Female 8/21/2013 Physician Dk
Primary
Secondary
Disease Progression Other Serious 31 Female 8/21/2013 Physician Dk
Primary
Secondary
Pain Hospitalization Female 106 lb 8/26/2013 Physician Au
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Female 134 lb 9/10/2013 Physician Us
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/2009 37 Female 156 lb 8/30/2013 Physician Us
Primary
Concomitant
Neoplasm Progression Other Serious Female 9/6/2013 Physician Ca
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 183 lb 9/18/2013 Physician Us
Primary
Secondary
Concomitant
Vaginal Haemorrhage Other Serious 2/2012 66 Female 190 lb 9/20/2013 Us
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious Female 194 lb 11/15/2013 Physician Us
Primary
Concomitant
Vomiting Other Serious Female 149 lb 10/7/2013 Physician Us
Primary
Concomitant
Weight Decreased Other Serious 3/8/2012 60 Female 10/8/2013 Physician Us
Primary
Secondary
Concomitant
Metastases To Spine Other Serious 47 Female 11/1/2013 Other Health Professional Gb
Primary
Concomitant
Metastases To Spine Other Serious 39 Female 11/1/2013 Other Health Professional Gb
Primary
Secondary
Concomitant
Rash Other Serious 55 Female 11/14/2013 Consumer Gb
Primary
Secondary
Vomiting Hospitalization 2007 58 Female 170 lb 10/18/2013 Consumer Mx
Primary
Secondary
Concomitant
Vocal Cord Thickening Death 2003 58 Female 146 lb 10/10/2013 Consumer Us
Primary
Secondary
Concomitant
Wheezing Hospitalization 2/5/1998 60 Female 167 lb 4/22/2013 Consumer Us
Primary
Secondary
Concomitant
Weight Decreased Death 11/29/2004 53 Female 7/17/2013 Consumer Us
Primary
Concomitant
Wound Other Serious 3/1/2002 50 Male 6/14/2013 Physician Us
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2002 51 Female 188 lb 4/23/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Secretion Other Serious 1/31/2005 81 Female 8/21/2013 Other Health Professional Us
Primary
Concomitant
Vomiting Other Serious 4/15/2003 56 Female Other Health Professional Us
Primary
Concomitant
Weight Decreased Other Serious Female 10/15/2013 Consumer Us
Primary
Secondary
Concomitant
Vascular Calcification Death 11/3/2008 44 Female 7/17/2013 Consumer Us
Primary
Concomitant
Visual Impairment Other Serious Female 8/8/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Disability 3/1/2002 50 Male 11/20/2013 Other Health Professional Us
Primary
Concomitant

Drug Data