Herceptin combined with Tamoxifen Citrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 12/11/2001 52 Female 2/24/2006 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 2/12/2006 46 Female 3/6/2006 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/1/2004 38 Female 3/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 3/1/2004 38 Female 4/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Skin Lesion Other Serious 11/1/2005 49 Female 150 lb 4/20/2006 Other Health Professional Brazil
Primary
Concomitant
Wound Debridement Other Serious 12/11/2001 52 Female 5/6/2006 United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 5/5/2006 46 Female 6/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Speech Disorder Other Serious Female 7/7/2006 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 5/26/2006 56 Female 185 lb 7/27/2006 Physician United Kingdom
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 12/2/2005 44 Female 124 lb 8/9/2006 Physician Australia
Primary
Secondary
Concomitant
Surgery Hospitalization 6/1/2005 Female 128 lb 8/25/2006 Physician France
Primary
Concomitant
Surgery Hospitalization 9/1/2005 Female 117 lb 8/25/2006 Physician France
Primary
Concomitant
Breast Cancer Metastatic Required Intervention 7/1/2005 55 Female 6/6/2006 Physician United States
Primary
Secondary
Pain In Extremity Required Intervention 11/14/2005 48 Female 270 lb 6/6/2006 Other Health Professional United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 41 Female 6/6/2006 Physician United States
Primary
Concomitant
Dilatation Ventricular Other Serious Female 6/6/2006 Consumer United States
Primary
Concomitant
Pleural Effusion Life Threatening 10/23/2005 38 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Myelodysplastic Syndrome Hospitalization 11/22/2005 44 Female 124 lb 9/11/2006 Physician Australia
Primary
Secondary
Concomitant
Sinus Tachycardia Other Serious 8/30/2006 30 Female 132 lb 9/21/2006 Physician Germany
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/22/2005 44 Female 124 lb 11/7/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 11/21/2006 United States
Primary
Secondary
Concomitant
Thyroiditis Other Serious 8/21/2006 49 Female 161 lb 11/20/2006 Physician Switzerland
Primary
Secondary
Speech Disorder Other Serious Female 12/4/2006 Pharmacist United States
Primary
Concomitant
Venoocclusive Liver Disease Hospitalization 11/22/2005 44 Female 124 lb 12/5/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/12/2007 United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 11/29/2006 Female 1/23/2007 Other Health Professional United States
Primary
Concomitant
Sepsis Neonatal Other Serious Male 3 lb 1/19/2007 Physician Austria
Primary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 1/25/2007 United States
Primary
Secondary
Concomitant
Thyroiditis Other Serious 8/21/2006 49 Female 161 lb 1/27/2007 Physician Switzerland
Primary
Secondary
Pancreatitis Hospitalization 11/29/2006 Female 2/6/2007 Other Health Professional United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 1/10/2006 47 Female 130 lb 2/7/2007 France
Primary
Secondary
Vomiting Other Serious 4/18/2003 42 Female 111 lb 2/16/2007 Lawyer United States
Primary
Concomitant
Pregnancy Other Serious 36 Female 2/13/2007 Pharmacist United Kingdom
Primary
Concomitant
Pericarditis Hospitalization 10/18/2006 30 Female 2/20/2007 Physician France
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 3/8/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 3/3/2000 48 Female 208 lb 3/14/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 6 lb 3/9/2007 Physician United Kingdom
Primary
Concomitant
Pregnancy Other Serious 9/7/2006 36 Female 3/9/2007 Pharmacist United Kingdom
Primary
Concomitant
Surgery Other Serious 64 Female 3/30/2007 Other Health Professional Brazil
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/13/2007 79 Female 4/4/2007 Physician Germany
Primary
Secondary
Concomitant
Left Ventricular Failure Other Serious Female 4/4/2007 Physician Germany
Primary
Secondary
Concomitant
Pericarditis Hospitalization 10/18/2006 30 Female 110 lb 4/5/2007 Other Health Professional France
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 Female 4/6/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 6 lb 4/4/2007 Physician United Kingdom
Primary
Concomitant
Pericarditis Hospitalization 10/18/2006 30 Female 110 lb 4/26/2007 Other Health Professional France
Primary
Concomitant
Vomiting Life Threatening 2/14/2007 50 Female 110 lb 4/24/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious Female 5/16/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 4/18/2003 5/30/2007 Lawyer United States
Primary
Concomitant
Vomiting Life Threatening 2/20/2007 50 Female 5/29/2007 United Kingdom
Primary
Secondary
Concomitant
Myositis Other Serious Female 6/19/2007 Physician United Kingdom
Primary
Concomitant
Fatigue 4/11/2007 55 Female 7/6/2007 Consumer United States
Primary
Concomitant
Paraesthesia 5/24/2007 47 Female 7/6/2007 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious Female 7/30/2007 Other Health Professional United States
Primary
Concomitant
Pain In Jaw Other Serious 5/10/2007 46 Female 119 lb 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Autoimmune Hepatitis Other Serious Female 8/15/2007 Other Health Professional United States
Primary
Concomitant
Sequestrectomy Other Serious 5/10/2007 46 Female 119 lb 9/1/2007 Physician Japan
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 6/29/2007 0 Male 4 lb 9/4/2007 Consumer New Zealand
Primary
Concomitant
Respiratory Distress Other Serious 6/29/2007 0 Male 4 lb 9/4/2007 Consumer New Zealand
Primary
Concomitant
Hepatic Cirrhosis Death 44 Female 9/4/2007 Other Health Professional Japan
Primary
Concomitant
Alveolitis Disability 6/8/2007 64 Female 141 lb 9/4/2007 Consumer United Kingdom
Primary
Concomitant
Pericardial Disease Other Serious 9/7/2007 Consumer United Kingdom
Primary
Secondary
Hepatic Cirrhosis Death 44 Female 9/11/2007 Consumer United Kingdom
Primary
Secondary
Cerebrovascular Accident Hospitalization 8/2/2007 44 Female 9/13/2007 Other Health Professional Australia
Primary
Concomitant
Hepatic Cirrhosis Death 44 Female 9/20/2007 Other Health Professional Japan
Primary
Concomitant
Pericardial Disease Other Serious 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Pain In Extremity Other Serious 3/1/2007 Female 145 lb 9/26/2007 Consumer United States
Primary
Concomitant
Hepatic Failure Death 44 Female 9/27/2007 Consumer United Kingdom
Primary
Secondary
Periostitis 1/1/2005 Female 193 lb 9/27/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious 3/1/2007 Female 145 lb 10/5/2007 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Other Serious Female 10/8/2007 Consumer United Kingdom
Primary
Concomitant
Visual Disturbance Other Serious 77 Female 10/19/2007 United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 8/2/2007 44 Female 10/17/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Sleep Disorder Other Serious Female 326 lb 10/25/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Hypertension Other Serious 60 Female 11/14/2007 Consumer United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/19/2007 42 Female 169 lb 12/17/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rash Maculo-papular Other Serious 9/1/2007 43 Female 12/17/2007 Pharmacist United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 1/1/2000 54 Female 146 lb 12/17/2007 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/19/2007 42 Female 169 lb 12/21/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/19/2007 42 Female 169 lb 12/19/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Polyneuropathy Hospitalization 51 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Rash Maculo-papular Other Serious 9/1/2007 43 Female 1/4/2008 Pharmacist United Kingdom
Primary
Concomitant
Stomach Discomfort 12/2/2007 45 Female 4/10/2008 Consumer United States
Primary
Concomitant
Hypothyroidism Disability 6/26/2007 47 Female 4/23/2008
Primary
Secondary
Hypothyroidism Other Serious 6/26/2007 Female 5/1/2008 Physician France
Primary
Concomitant
Hypothyroidism Disability 6/26/2007 Female 5/5/2008 Physician United Kingdom
Primary
Secondary
Hypothyroidism Disability 6/26/2007 47 Female 5/7/2008 Consumer France
Primary
Secondary
Acute Coronary Syndrome Other Serious 58 Female 5/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Disability 3/11/2008 44 Female 5/28/2008
Primary
Secondary
Hypothyroidism Disability 3/11/2008 Female 5/30/2008 Other Health Professional France
Primary
Concomitant
Hypothyroidism Disability 3/11/2008 44 Female 5/30/2008 Consumer France
Primary
Secondary
Fibrosis Hospitalization 4/4/2008 Female 116 lb 5/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Hypothyroidism Disability 3/11/2008 44 Female 6/3/2008 Other Health Professional United States
Primary
Secondary
Hypothyroidism Disability 3/11/2008 Female 6/12/2008 Physician France
Primary
Secondary
Troponin Increased Hospitalization 5/4/2008 Female 152 lb 6/19/2008 Physician United Kingdom
Primary
Concomitant
Troponin Increased Hospitalization 5/4/2008 Female 152 lb 7/8/2008 Physician United Kingdom
Primary
Concomitant
Hepatic Failure Other Serious 44 Female 7/14/2008 Other Health Professional Japan
Primary
Concomitant
Tremor Disability 3/14/2008 Female 7/25/2008 Pharmacist United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 5/26/2006 Female 185 lb 7/28/2008 Consumer United Kingdom
Primary
Concomitant
Haemoglobin Decreased Other Serious 71 Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Toothache Other Serious 2/5/1998 Female 167 lb 8/13/2008 United States
Primary
Secondary
Concomitant
Vasospasm Other Serious 10/16/1995 Female 167 lb 9/10/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Disorder Other Serious 10/16/1995 Female 167 lb 9/23/2008 United States
Primary
Secondary
Concomitant
Retching 12/2/2007 45 Female 10/10/2008 Consumer United States
Primary
Concomitant
Renal Disorder Other Serious 1/1/2008 Male 4 lb 10/15/2008 Consumer New Zealand
Primary
Concomitant
Disease Progression Death 35 Female 108 lb 10/27/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 10/1/2008 54 Female 10/27/2008 Physician United Kingdom
Primary
Concomitant
Renal Disorder Other Serious 1/1/2008 Male 4 lb 10/30/2008 Consumer New Zealand
Primary
Concomitant
Carpal Tunnel Syndrome Disability 12/9/2008 Female 1/20/2009 Consumer United Kingdom
Primary
Concomitant
Weight Increased Other Serious 3/3/2000 Female 208 lb 2/26/2009 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 3/3/2000 Female 208 lb 2/25/2009 Physician United States
Primary
Secondary
Concomitant
Eczema Disability 56 Female 4/13/2009 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 8/1/2008 Female 4/17/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Tricuspid Valve Incompetence Other Serious 2/5/2009 Female 4/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 5/5/2009 Other Health Professional United Kingdom
Primary
Secondary
Tremor Other Serious 2/28/2008 39 Female 5/8/2009 Pharmacist United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 1/1/2008 36 Female 5/18/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Disease Progression Other Serious 5/18/2009 Physician United Kingdom
Primary
Concomitant
Metastases To Liver Other Serious 36 Female 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 6 lb 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sudden Death Death 3/23/2009 Female 5/21/2009 Consumer Portugal
Primary
Secondary
Concomitant
Caesarean Section Other Serious 9/7/2006 36 Female 5/22/2009 Consumer United Kingdom
Primary
Secondary
Pulmonary Hypoplasia Death Female 6 lb 5/22/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Death Female 6 lb 5/28/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Caesarean Section Other Serious 9/7/2006 36 Female 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Hypoplasia Death Female 6 lb 6/3/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Hypoplasia Other Serious Female 6/12/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Wheezing Other Serious 3/25/1997 Female 126 lb 6/26/2009 Physician United States
Primary
Secondary
Concomitant
Hair Growth Abnormal Other Serious 3/15/2009 47 Female 7/8/2009 Consumer United Kingdom
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Pulmonary Hypoplasia Other Serious Female 7/22/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 1/1/2006 Female 7/23/2009 Other Health Professional United States
Primary
Concomitant
Tumour Invasion Other Serious 1/1/2006 Female 7/24/2009 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious Male 4 lb 7/28/2009 Other Health Professional New Zealand
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious Male 4 lb 7/28/2009 Other Health Professional New Zealand
Primary
Concomitant
Decubitus Ulcer Other Serious 59 Female 9/7/2009 Consumer United States
Primary
Concomitant
Sudden Death Death 3/1/2009 Female 9/15/2009 Consumer Portugal
Primary
Secondary
Concomitant
Skin Laceration 5/30/2009 46 Female 183 lb 9/24/2009 Consumer United States
Primary
Concomitant
Diarrhoea 8/20/2009 28 Female 9/24/2009 Consumer United States
Primary
Concomitant
Tumour Invasion Other Serious 1/1/2006 Female 10/12/2009 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 2/1/1998 Female 126 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/1/2008 Female 195 lb 10/26/2009 Physician United States
Primary
Secondary
Concomitant
Mastectomy Hospitalization 12/1/2008 36 Female 11/2/2009 Consumer United Kingdom
Primary
Secondary
Vomiting Other Serious 8/1/2003 Female 11/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tumour Invasion Other Serious 1/1/2006 Female 11/10/2009 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Other Serious Female 11/12/2009 Physician Slovakia (Slovak Republic)
Primary
Concomitant
Breast Mass Hospitalization Female 11/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 11/5/2009 83 Female 160 lb 11/12/2009 Other Health Professional United States
Primary
Concomitant
Anosmia Disability 2/1/2009 Female 132 lb 12/8/2009 Physician Australia
Primary
Concomitant

Drug Data