Herceptin combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Chest Pain Hospitalization 1/2/2005 58 Female 154 lb 1/9/2006 Physician Netherlands
Primary
Secondary
Chest Pain Hospitalization 1/2/2005 58 Female 154 lb 1/13/2006 Physician Netherlands
Primary
Secondary
Somnolence Other Serious 1/1/2005 46 Female 176 lb 1/18/2006 Physician Denmark
Primary
Secondary
Polymyositis Other Serious 54 Female 156 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 12/25/2005 45 Female 148 lb 1/23/2006 Other Health Professional Netherlands
Primary
Secondary
Polymyositis Other Serious 7/7/2005 54 Female 156 lb 1/30/2006 Physician United States
Primary
Secondary
Concomitant
Erythema Other Serious 1/28/2005 24 Female 269 lb 2/6/2006 Consumer United States
Primary
Concomitant
Neuropathy Peripheral 53 Female 2/6/2006 Consumer United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2005 46 Female 176 lb 2/28/2006 Physician Denmark
Primary
Secondary
Infusion Related Reaction Other Serious 10/1/2005 72 Female 3/10/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/2/2005 57 Female 112 lb 3/31/2006 Physician Japan
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/2/2005 57 Female 112 lb 5/3/2006 Physician Japan
Primary
Concomitant
Febrile Neutropenia Hospitalization 11/17/2005 52 Female 272 lb 5/11/2006 Physician Spain
Primary
Secondary
Concomitant
Polymyositis Other Serious 7/7/2005 54 Female 156 lb 5/16/2006 Physician United States
Primary
Secondary
Concomitant
Troponin Increased Hospitalization 10/15/2005 49 Female 190 lb 6/14/2006 Physician United States
Primary
Concomitant
Sepsis Other Serious 7/24/2006 Pharmacist United Kingdom
Primary
Secondary
Palpitations Hospitalization 6/20/2006 52 Female 291 lb 7/31/2006 Physician United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Hospitalization 5/5/2006 55 Female 166 lb 6/6/2006 Pharmacist United States
Primary
Concomitant
Urticaria Other Serious 10/1/2005 71 Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Cardiotoxicity Other Serious Female 6/6/2006 Pharmacist United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious Female 6/6/2006 Consumer United States
Primary
Concomitant
Lung Infiltration Hospitalization 9/18/2005 66 Female 6/6/2006 Physician United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious Female 6/6/2006 Physician United States
Primary
Concomitant
Hypersensitivity Other Serious 10/19/2005 77 Female 6/6/2006 Other Health Professional United States
Primary
Concomitant
Heart Rate Increased Hospitalization 8/21/2006 38 Female 9/7/2006 Physician China
Primary
Concomitant
Rash Other Serious 6/7/2006 48 Female 132 lb 9/7/2006 Netherlands
Primary
Concomitant
Loss Of Proprioception Other Serious 5/30/2006 51 Female 132 lb 9/7/2006 Pharmacist Netherlands
Primary
Concomitant
Sepsis Hospitalization 7/5/2006 54 Female 198 lb 9/14/2006 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Anaphylactoid Reaction Hospitalization 7/6/2006 62 Female 139 lb 9/14/2006 Physician France
Primary
Concomitant
Tooth Extraction Other Serious 5/1/2006 62 Female 9/21/2006 Physician Japan
Primary
Concomitant
Heart Rate Increased Hospitalization 8/21/2006 38 Female 9/21/2006 Physician China
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Heart Rate Increased Hospitalization 8/21/2006 38 Female 10/11/2006 Physician China
Primary
Concomitant
Lymphoedema Other Serious 65 Female 10/24/2006 Pharmacist United Kingdom
Primary
Concomitant
Lymphoedema Other Serious 6/1/2006 65 Female 11/2/2006 Pharmacist United Kingdom
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 11/17/2006 54 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Confusional State Other Serious 10/15/2006 60 Female 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 59 Female 12/6/2006 Pharmacist United Kingdom
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/29/2005 71 Female 12/27/2006 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 11/17/2006 54 Female 1/8/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/29/2005 71 Female 154 lb 1/17/2007 Physician Japan
Primary
Secondary
Concomitant
Sepsis Neonatal Other Serious Male 3 lb 1/19/2007 Physician Austria
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2003 62 Female 1/26/2007 Physician Japan
Primary
Concomitant
Swelling Face Death 12/16/2006 54 Female 1/26/2007 Physician India
Primary
Secondary
Concomitant
Platelet Count Decreased Other Serious 7/29/2005 71 Female 154 lb 1/26/2007 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 11/21/2006 52 Female 1/26/2007 Physician India
Primary
Secondary
White Blood Cell Count Decreased Hospitalization 12/12/2006 38 Female 1/26/2007 Physician India
Primary
Secondary
Metastases To Lung Death 65 Female 2/2/2007 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 2/4/2007 32 Female 99 lb 3/1/2007 Other Health Professional India
Primary
Secondary
Tooth Extraction Other Serious 8/1/2003 63 Female 3/15/2007 Physician Japan
Primary
Concomitant
Pain In Extremity Hospitalization Female 3/14/2007 Consumer Argentina
Primary
Secondary
Dysarthria Other Serious 9/27/2006 61 Female 132 lb 3/15/2007 Physician Japan
Primary
Concomitant
Interstitial Lung Disease Other Serious 2/28/2007 67 Female 3/15/2007 Physician Japan
Primary
Concomitant
Rash Other Serious 3/15/2007 Female 169 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Surgery Other Serious 64 Female 3/30/2007 Other Health Professional Brazil
Primary
Concomitant
Respiratory Failure Life Threatening 67 Female 115 lb 3/27/2007 Physician Japan
Primary
Concomitant
Pancytopenia Life Threatening 12/1/2006 37 Female 4/12/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Required Intervention 3/2/2007 61 Female 4/5/2007 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Life Threatening Female 115 lb 4/20/2007 Physician United Kingdom
Primary
Concomitant
Dysarthria Other Serious 9/27/2006 Female 132 lb 5/10/2007 Physician United Kingdom
Primary
Concomitant
Stomatitis Life Threatening 3/30/2007 Female 5/17/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 4/27/2007 Female 6/26/2007 Consumer United Kingdom
Primary
Concomitant
Nephritis Interstitial Other Serious 76 Female 7/10/2007 Physician United Kingdom
Primary
Concomitant
Gastric Ulcer Other Serious Female 7/24/2007 Physician United Kingdom
Primary
Secondary
Nephritis Interstitial Other Serious 76 Female 7/24/2007 Physician United Kingdom
Primary
Concomitant
Hypoacusis Other Serious 69 Female 8/1/2007 Physician United States
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/14/2007 Japan
Primary
Concomitant
Recall Phenomenon 41 Female 8/24/2007 Physician United States
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 63 Female 8/28/2007 Japan
Primary
Concomitant
Cardiac Disorder Other Serious 66 Female 9/10/2007 Consumer United States
Primary
Concomitant
Hepatic Cirrhosis Death 44 Female 9/11/2007 Consumer United Kingdom
Primary
Secondary
Hyposmia Other Serious 7/3/2007 51 Female 9/11/2007 Consumer United Kingdom
Primary
Secondary
Myocardial Infarction Other Serious 52 Female 9/12/2007 Physician United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious Female 9/24/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 54 Female 198 lb 9/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Death 44 Female 9/27/2007 Consumer United Kingdom
Primary
Secondary
Tooth Extraction Hospitalization 1/31/2006 63 Female 10/2/2007 Japan
Primary
Concomitant
Interstitial Lung Disease Hospitalization 5/11/2007 Female 10/3/2007 Consumer United Kingdom
Primary
Concomitant
Interstitial Lung Disease Other Serious 9/1/2007 69 Female 126 lb 10/5/2007 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 11/17/2006 71 Female 125 lb 12/12/2006 Consumer United States
Primary
Concomitant
Rash Other Serious 1/23/2007 46 Female 177 lb 4/27/2007 Physician United States
Primary
Concomitant
Pain Other Serious 2/28/2007 43 Female 200 lb 4/27/2007 Physician United States
Primary
Concomitant
Eyelid Oedema Other Serious 8/22/2007 45 Female 198 lb 10/10/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Death 7/5/2006 54 Female 198 lb 10/9/2007 United Kingdom
Primary
Secondary
Concomitant
Hepatitis B Other Serious 10/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Interstitial Lung Disease Other Serious 9/1/2007 69 Female 126 lb 10/22/2007 Physician United Kingdom
Primary
Concomitant
Hyposmia Other Serious 7/3/2007 Female 170 lb 10/23/2007 Consumer United Kingdom
Primary
Concomitant
Gait Disturbance Other Serious Female 11/13/2007 Physician United Kingdom
Primary
Concomitant
Blood Bilirubin Increased Other Serious 11/28/2007 Other Health Professional United Kingdom
Primary
Secondary
Death Death 61 Female 12/4/2007 Physician United Kingdom
Primary
Concomitant
Death Death Female 12/5/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 12/11/2007 Physician
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/14/2007 Physician
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/18/2007 Female 12/14/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Road Traffic Accident Hospitalization 12/11/2007 Female 12/18/2007 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Toxicity Other Serious 1/1/2003 58 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/16/2007 59 Female 95 lb 12/29/2007 Physician
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/18/2007 Female 12/31/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Metastases To Central Nervous System Other Serious 36 Female 1/18/2008 Italy
Primary
Concomitant
Pneumonia Other Serious 9/11/2007 59 Female 95 lb 2/6/2008 Physician
Primary
Secondary
Concomitant
Demyelination Other Serious 3/1/2008 45 Female 4/1/2008 Consumer United Kingdom
Primary
Concomitant
Demyelination Other Serious 3/1/2008 45 Female 4/10/2008 Consumer United Kingdom
Primary
Concomitant
Necrosis Other Serious Female 4/24/2008 Physician United Kingdom
Primary
Secondary
Plantar Erythema Other Serious 1/23/2008 50 Female 148 lb 4/25/2008 Physician Netherlands
Primary
Concomitant
Demyelination Other Serious 3/1/2008 45 Female 5/12/2008 Consumer China
Primary
Concomitant
Urticaria Other Serious 10/31/2007 53 Female 275 lb 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Paralysis Other Serious 70 Female 6/24/2008 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2007 71 Female 117 lb 7/10/2008 Other Health Professional Japan
Primary
Secondary
Tooth Extraction Other Serious 1/1/2007 Female 117 lb 7/14/2008 Other Health Professional Japan
Primary
Secondary
Back Pain Other Serious 7/11/2007 59 Female 214 lb 11/6/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 8/29/2008
Primary
Concomitant
Renal Disorder Other Serious 1/1/2008 Male 4 lb 10/15/2008 Consumer New Zealand
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/20/2008 Japan
Primary
Concomitant
Tooth Extraction Hospitalization 1/31/2006 Female 10/28/2008 Japan
Primary
Concomitant
Renal Disorder Other Serious 1/1/2008 Male 4 lb 10/30/2008 Consumer New Zealand
Primary
Concomitant
Premature Rupture Of Membranes Other Serious 1/1/2007 28 Female 11/3/2008 Consumer New Zealand
Primary
Concomitant
Dementia Other Serious Female 11/10/2008 Physician Germany
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 50 Female 128 lb 11/19/2008 Physician China
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/14/2008 Female 172 lb 11/17/2008 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 64 Female 168 lb 11/25/2008 Physician United States
Primary
Secondary
Necrosis Other Serious 11/1/2008 40 Female 12/2/2008 Consumer China
Primary
Concomitant
Tooth Extraction Other Serious 1/31/2006 Female 12/2/2008 Japan
Primary
Concomitant
Ejection Fraction Decreased Other Serious 58 Female 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 10/30/2008 Female 12/15/2008 Consumer United Kingdom
Primary
Secondary
Peripheral Sensory Neuropathy Other Serious 5/17/2008 Female 12/18/2008 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 4/21/2001 52 Female 146 lb 12/18/2008 Consumer France
Primary
Secondary
Tooth Extraction Other Serious 11/18/2003 Female 12/19/2008 Japan
Primary
Concomitant
Blood Bilirubin Increased Other Serious 12/19/2008 Physician United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 10/8/2008 50 Female 128 lb 12/23/2008 Physician China
Primary
Secondary
Concomitant
Infusion Related Reaction Death 10/22/2002 Female 12/23/2008 Physician Denmark
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 10/30/2008 Female 12/23/2008 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/8/2008 50 Female 128 lb 12/30/2008 Physician China
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 11/25/2008 60 Female 12/30/2008 Consumer United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/5/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 1/16/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
T-cell Lymphoma Life Threatening 4/1/2008 Female 2/11/2009 Physician France
Primary
Secondary
Toothache Other Serious 1/18/2007 Female 132 lb 3/13/2009 Physician Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 2/3/2009 Female 3/13/2009 Physician United Kingdom
Primary
Secondary
Hepatic Enzyme Increased Other Serious 2/16/2009 Female 3/18/2009 Physician United Kingdom
Primary
Secondary
Pancytopenia Other Serious 1/1/2008 47 Female 3/26/2009 Consumer Japan
Primary
Concomitant
Skin Toxicity Other Serious 66 Female 3/6/2009 Other Health Professional Spain
Primary
Concomitant
Pancytopenia Other Serious 1/1/2008 47 Female 4/6/2009 Consumer Japan
Primary
Concomitant
Toothache Other Serious 1/18/2007 Female 132 lb 4/20/2009 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 1/26/2009 Female 4/23/2009 Consumer United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 1/26/2009 Female 5/13/2009 Consumer United Kingdom
Primary
Concomitant
Pulmonary Oedema Death Female 5/15/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Visual Impairment Other Serious 31 Female 5/12/2009 Consumer United Kingdom
Primary
Secondary
Concomitant

Drug Data