Herceptin combined with Navelbine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Wound Debridement Other Serious 4/1/2005 48 Female 117 lb 1/10/2006 Physician France
Primary
Secondary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 1/18/2006 Physician Japan
Primary
Concomitant
Oropharyngeal Candidiasis Death Female 2/14/2006 Physician Spain
Primary
Secondary
Concomitant
Pulmonary Embolism Required Intervention 2/15/2006 Female 155 lb 2/16/2006 United States
Primary
Secondary
Vomiting Other Serious 6/27/2001 Female 2/24/2006 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Oedema Death 7/19/2005 75 Female 3/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious Female 3/6/2006 Physician United States
Primary
Concomitant
Tooth Extraction Other Serious 4/18/2003 42 Female 111 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Tooth Extraction Hospitalization 4/1/2005 25 Female 132 lb 5/5/2006 France
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 3/15/2005 25 Female 4/6/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/15/2006 Female 5/19/2006 Physician United States
Primary
Concomitant
Cardiac Failure Death 3/13/2006 62 Female 5/24/2006 Physician Japan
Primary
Concomitant
Pulmonary Oedema Death Female 5/30/2006 Physician Germany
Primary
Concomitant
Pulmonary Oedema Death 5/9/2006 43 Female 148 lb 6/13/2006 Physician Germany
Primary
Secondary
Concomitant
Oropharyngeal Candidiasis Death Female 6/14/2006 Physician Spain
Primary
Secondary
Concomitant
Myocardial Infarction Death 3/13/2006 62 6/19/2006 Physician Japan
Primary
Concomitant
Toothache 3/11/2006 46 Female 208 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 3/26/2004 64 Female 106 lb 6/21/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/15/2006 Female 6/28/2006 Physician United States
Primary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 8/4/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2006 60 Female 8/12/2006 Physician Japan
Primary
Concomitant
Surgery Hospitalization 9/1/2005 Female 117 lb 8/25/2006 Physician France
Primary
Concomitant
Chest Pain Hospitalization Female 8/24/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Female 6/6/2006 Consumer United States
Primary
Concomitant
Pleural Effusion Hospitalization 57 6/6/2006 Other Health Professional United States
Primary
Concomitant
Rash Macular Required Intervention 4/13/2005 61 Female 6/6/2006 Physician United States
Primary
Concomitant
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 9/11/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Pancytopenia Other Serious 11/1/2005 62 Female 9/9/2006 Japan
Primary
Secondary
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 9/15/2006 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 5/1/2006 62 Female 9/21/2006 Physician Japan
Primary
Concomitant
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Tachycardia Death 43 Female 10/6/2006 Germany
Primary
Concomitant
Pancytopenia Other Serious 3/1/2006 62 Female 10/25/2006 Consumer France
Primary
Secondary
Pulmonary Oedema Death 43 Female 10/24/2006 Germany
Primary
Concomitant
Pancytopenia Other Serious 11/1/2005 62 Female 10/31/2006 Japan
Primary
Secondary
Tooth Abscess Death 5/9/2006 43 Female 148 lb 11/6/2006 Physician Germany
Primary
Secondary
Concomitant
Pyrexia Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Periodontitis Disability 1/1/2004 50 Female 11/15/2006 Switzerland
Primary
Concomitant
Restlessness Death 5/9/2006 43 Female 148 lb 11/10/2006 Physician Germany
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 3/13/2006 56 Female 190 lb 11/18/2006 Other Health Professional Brazil
Primary
Concomitant
Wound Debridement Other Serious 11/1/2005 67 Female 134 lb 11/18/2006 Physician Brazil
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 11/20/2006 Lawyer United States
Primary
Secondary
Concomitant
Nerve Injury Other Serious Female 12/7/2006 Consumer Germany
Primary
Secondary
Pulmonary Oedema Life Threatening Female 152 lb 12/5/2006 Physician Germany
Primary
Secondary
Neuropathy Peripheral Life Threatening 9/1/2006 Female 11/20/2006 Japan
Primary
Concomitant
Oligohydramnios Other Serious 26 Female 12/4/2006 United States
Primary
Secondary
White Blood Cell Count Increased Life Threatening Female 152 lb 12/15/2006 Physician Germany
Primary
Secondary
Wound Debridement Other Serious 10/1/2002 58 Female 142 lb 12/28/2006 Physician United States
Primary
Secondary
Concomitant
Trismus Other Serious 3/1/2000 53 Female 1/8/2007 United States
Primary
Secondary
Concomitant
Treatment Related Secondary Malignancy Other Serious 3/1/2006 62 Female 1/9/2007 Consumer United States
Primary
Secondary
Neuropathy Life Threatening 9/1/2006 Female 12/13/2006 Japan
Primary
Concomitant
Peritoneal Lesion Life Threatening 12/4/2006 55 Female 1/8/2007 Physician Japan
Primary
Concomitant
Tooth Extraction Disability 2/1/2005 37 Female 1/27/2007 France
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2003 62 Female 1/26/2007 Physician Japan
Primary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/6/2007 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 66 Female 159 lb 2/14/2007 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2003 42 Female 111 lb 2/16/2007 Lawyer United States
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 2/23/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 3/8/2007 Japan
Primary
Concomitant
Tooth Extraction Other Serious 8/1/2003 63 Female 3/15/2007 Physician Japan
Primary
Concomitant
Condition Aggravated Other Serious 9/1/2006 Female 3/13/2007 Physician Japan
Primary
Concomitant
Chest Pain Hospitalization Female 3/10/2007 Other Health Professional United States
Primary
Concomitant
Deafness Other Serious 2/1/2007 58 Female 3/20/2007 Physician Japan
Primary
Secondary
Tremor Death 1/6/2007 69 Female 3/22/2007 Japan
Primary
Concomitant
Urinary Tract Infection Other Serious 75 Female 3/16/2007 Japan
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 2/13/2007 79 Female 4/4/2007 Physician Germany
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2005 Female 127 lb 4/11/2007 United States
Primary
Concomitant
Tooth Abscess Other Serious 2/1/2007 Female 4/13/2007 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 30 Female 5/15/2007 Pharmacist United States
Primary
Concomitant
Throat Irritation Other Serious 3/11/2006 46 Female 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/18/2003 5/30/2007 Lawyer United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 2/15/2007 79 Female 6/4/2007 Physician Germany
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/20/2007 50 Female 5/29/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 6/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 Female 6/19/2007 Physician United States
Primary
Secondary
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/6/2007 Japan
Primary
Concomitant
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 7/11/2007 Japan
Primary
Concomitant
Deafness Other Serious 2/11/2007 58 Female 7/18/2007 Physician United Kingdom
Primary
Secondary
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Wound Debridement Other Serious 1/1/2001 Female 167 lb 7/19/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 6/19/2007 Female 7/25/2007 Physician United Kingdom
Primary
Concomitant
Vomiting Other Serious 6/19/2007 Female 198 lb 8/9/2007 Physician United Kingdom
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Pain In Jaw Other Serious 6/19/2007 53 Female 8/22/2007 United States
Primary
Concomitant
Optic Nerve Disorder Other Serious Female 8/9/2007 Germany
Primary
Secondary
Pyrexia Other Serious 12/1/2005 75 Female 9/6/2007 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 6/15/2007 75 Female 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Bronchial Hyperreactivity Other Serious 12/11/2006 Female 106 lb 10/12/2007 Consumer United Kingdom
Primary
Concomitant
Tooth Extraction Other Serious 12/1/2003 46 Female 166 lb 10/29/2007 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 10/19/2007 Female 171 lb 10/25/2007 United States
Primary
Secondary
Wound Treatment Other Serious 6/1/2005 69 Female 128 lb 11/2/2007 Japan
Primary
Concomitant
Lethargy Other Serious 10/1/2007 Female 11/6/2007 Consumer United Kingdom
Primary
Concomitant
Pyrexia Hospitalization 10/19/2007 Female 171 lb 11/2/2007 United States
Primary
Secondary
Wound Treatment Hospitalization 6/1/2005 69 Female 128 lb 11/20/2007 Japan
Primary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 63 Female 12/12/2007 Physician United States
Primary
Secondary
Sequestrectomy Other Serious 2/1/2007 Female 12/19/2007 Physician Germany
Primary
Concomitant
Neutropenia Other Serious 1/1/2007 61 Female 12/27/2007 Physician United Kingdom
Primary
Concomitant
Sepsis Other Serious 6/1/2005 47 Female 12/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 47 Female 12/28/2007 Physician United Kingdom
Primary
Concomitant
Osteonecrosis Disability 52 Female 1/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Osteonecrosis Disability 4/20/2006 Female 2/14/2008 Physician United Kingdom
Primary
Secondary
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 2/14/2008 United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 4/20/2006 Female 2/20/2008 Physician United Kingdom
Primary
Secondary
Tooth Extraction Other Serious 1/1/2003 46 Female 170 lb 2/29/2008 United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 3/3/2008 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 3/5/2008 47 Female 3/18/2008 Italy
Primary
Secondary
Rash Other Serious 1/1/2008 48 Female 3/26/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Osteonecrosis Disability 1/20/2006 55 Female 3/29/2008 Physician Japan
Primary
Secondary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 11/2/2007 62 Female 4/2/2008 Consumer United States
Primary
Secondary
Concomitant
Tumour Marker Increased Other Serious 1/1/2000 67 Female 167 lb 4/12/2008 United States
Primary
Secondary
Concomitant
Sequestrectomy Other Serious 9/1/2007 Female 4/16/2008 Physician Germany
Primary
Concomitant
Swelling Face Other Serious Female 4/14/2008 Netherlands
Primary
Secondary
Concomitant
Renal Function Test Abnormal Hospitalization 2/7/2008 Female 4/14/2008 Denmark
Primary
Secondary
Pyrexia Hospitalization 12/18/2007 67 Female 4/23/2008 Japan
Primary
Concomitant
Thrombocytopenia Hospitalization 3/6/2008 58 Female 4/22/2008 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/29/2005 Female 5/13/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 6/14/2007 63 Female 5/14/2008 Physician United States
Primary
Secondary
Vocal Cord Paralysis Other Serious 1/1/2000 Female 167 lb 6/2/2008 United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 9/25/2007 67 Female 6/3/2008 Japan
Primary
Secondary
Concomitant
Convulsion Other Serious Female 6/26/2008 Consumer United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/25/2007 Female 82 lb 7/2/2008 Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 7/11/2008 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 10/11/2004 Female 7/15/2008 Other Health Professional United Kingdom
Primary
Secondary
Vocal Cord Paralysis Other Serious 60 Female 7/21/2008 Physician United Kingdom
Primary
Concomitant
Metastases To Central Nervous System Other Serious 7/8/2008 Female 7/21/2008 Consumer Poland
Primary
Concomitant
Somnolence Other Serious 7/8/2008 Female 7/24/2008 Consumer Poland
Primary
Concomitant
White Blood Cell Count Increased Other Serious 8/29/2006 Female 8/8/2008 Physician United States
Primary
Secondary
Concomitant
Haemoglobin Decreased Other Serious 71 Female 8/6/2008 Other Health Professional United States
Primary
Concomitant
Vasculitis Hospitalization 7/22/2008 41 Female 8/13/2008 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Muscle Spasms Other Serious 6/6/2008 Female 8/14/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/22/2008 Female 8/18/2008 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Other Serious 6/27/2001 8/18/2008 Lawyer United States
Primary
Secondary
Concomitant
Carcinoembryonic Antigen Increased Other Serious Female 8/22/2008 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Hospitalization 7/22/2008 Female 8/25/2008 Consumer Taiwan, Province Of China
Primary
Secondary
Concomitant
Optic Neuritis Other Serious 65 Male 9/17/2008 Physician Portugal
Primary
Concomitant
Optic Neuritis Other Serious 65 Male 9/19/2008 Physician Portugal
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/4/2008 Male 10/9/2008 Physician Portugal
Primary
Concomitant
Visual Acuity Reduced Other Serious 8/4/2008 Male 10/9/2008 Physician Portugal
Primary
Concomitant
Vocal Cord Paralysis Hospitalization 46 Female 10/29/2008 Consumer United States
Primary
Concomitant
Vocal Cord Paralysis Hospitalization 46 Female 11/7/2008 Consumer United States
Primary
Concomitant
Trismus Other Serious 9/1/1999 11/22/2008 United States
Primary
Secondary
Concomitant
Vocal Cord Paralysis Hospitalization 46 Female 12/5/2008 Consumer United States
Primary
Concomitant
Large Intestine Perforation Life Threatening 12/4/2006 55 Female 103 lb 12/2/2008 Physician Japan
Primary
Concomitant
Lymphoedema Hospitalization 10/2/2006 Female 12/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Visual Acuity Reduced Other Serious 8/4/2008 Male 12/10/2008 Physician Portugal
Primary
Concomitant
Weight Increased Other Serious 46 Female 12/12/2008 Consumer United States
Primary
Concomitant
Trismus Hospitalization 3/5/2008 45 Female 12/12/2008 Physician Italy
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/19/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 9/25/2007 Female 82 lb 12/29/2008 Other Health Professional Japan
Primary
Secondary
Concomitant

Drug Data