Heparin combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Thrombophlebitis Death 10/18/2005 57 Male 12/27/2005 Pharmacist United States
Primary
Secondary
Thrombosis Other Serious 8/29/1999 46 Female 126 lb 3/3/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 54 Female 2/24/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Abnormal Other Serious 2/24/2006 Female 4/13/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2002 42 Female 201 lb 4/17/2006 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 1/2/2006 80 Female 153 lb Pharmacist United States
Primary
Secondary
Pneumonia Aspiration Disability 4/11/2006 61 Female 137 lb 5/16/2006 Pharmacist United States
Primary
Secondary
Staphylococcal Bacteraemia Death 43 Female 9/29/2006
Primary
Concomitant
Endocarditis Other Serious Female 155 lb 4/18/2008 Other Health Professional United States
Primary
Concomitant
Haemorrhage Hospitalization 82 Male 12/26/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Retroperitoneal Haematoma Life Threatening 57 Male 1/2/2009 Germany
Primary
Secondary
Concomitant
Hypotension Other Serious 49 Female 1/13/2009 United States
Primary
Concomitant
Skin Necrosis Other Serious 64 Female 1/30/2009 United States
Primary
Secondary
Arterial Haemorrhage Life Threatening 10/30/2007 Male 157 lb 2/6/2009 Physician Canada
Primary
Concomitant
Thrombosis Hospitalization 1/7/2009 69 Male 159 lb 2/9/2009 Physician Germany
Primary
Concomitant
Urticaria Hospitalization 3/29/2008 2/10/2009 Other Health Professional France
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 11/12/2008 Female 3/2/2009 Consumer United States
Primary
Secondary
Concomitant
Leg Amputation Required Intervention 12/2/2008 Female 134 lb 3/10/2009 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Other Serious 4/1/2009 India
Primary
Secondary
Orthostatic Hypotension Hospitalization 11/20/2007 68 Male 4/28/2009 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Qt Prolonged Other Serious 4/2/2009 75 Female 128 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/1/2009 77 5/26/2009 Japan
Primary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 5/1/2009 77 6/10/2009 Japan
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 12/1/2008 68 6/19/2009 Other Health Professional Japan
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/7/2009 89 Female 93 lb 6/19/2009 Physician Japan
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 12/15/2008 68 6/26/2009 Other Health Professional Japan
Primary
Concomitant
Rash Hospitalization 4/24/2009 48 Male 238 lb 5/6/2009 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 3/30/2009 66 Male 198 lb 5/4/2009 Pharmacist United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/7/2009 89 Female 93 lb 7/2/2009 Physician Japan
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Life Threatening 53 Male 7/7/2009 Hong Kong
Primary
Concomitant
Interacting
Pulmonary Embolism Hospitalization 11/12/2008 Female 8/7/2009 Consumer United States
Primary
Secondary
Concomitant
Increased Tendency To Bruise Other Serious Female 8/24/2009 Other Health Professional United Kingdom
Primary
Interacting
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Pelvic Infection Required Intervention 6/23/2009 25 Female 178 lb 7/6/2009 Pharmacist United States
Primary
Concomitant
Laboratory Test Abnormal Required Intervention 6/28/2009 66 Male 172 lb 7/9/2009 United States
Primary
Concomitant
Somnolence Required Intervention 6/29/2009 69 Male 270 lb 7/2/2009 United States
Primary
Concomitant
Vena Cava Thrombosis Other Serious 11 Female 150 lb 9/25/2009
Primary
Secondary
Refusal Of Treatment By Patient Hospitalization 6/2/2009 Female 198 lb 7/5/2009 Pharmacist United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 4/24/2009 Female 110 lb 10/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/17/2009 Male 185 lb 10/30/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 5/4/2009 58 Male 11/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Peritonitis Bacterial Hospitalization 75 Male 11/3/2009 Other Health Professional United States
Primary
Concomitant
Haemoglobin Decreased Required Intervention 10/26/2009 56 Male 130 lb 10/28/2009 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 4/17/2009 Male 185 lb 1/12/2010 Other Health Professional United States
Primary
Secondary
Haematuria Life Threatening 12/7/2009 Female 146 lb 1/19/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Haematuria Life Threatening 12/7/2009 Female 146 lb 1/26/2010 Physician Russian Federation
Primary
Secondary
Concomitant
Electrocardiogram Qrs Complex Prolonged Death 1/1/2010 81 Male 128 lb 5/11/2010 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Other Serious 27 5/13/2010 India
Primary
Secondary
Weight Decreased Hospitalization 79 Female 5/18/2010 Lawyer United States
Primary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 6/14/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 1/13/2010 38 Male 6/15/2010 Physician United Kingdom
Primary
Concomitant
Pneumonia Life Threatening 11/20/2009 81 Male 101 lb 6/18/2010 Physician Japan
Primary
Secondary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/21/2010 United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 10/7/2009 66 Male 241 lb 6/23/2010 Physician United Kingdom
Primary
Concomitant
Coagulation Time Prolonged 10/26/2008 43 Female 6/24/2010 Pharmacist United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 10/7/2009 66 Male 241 lb 6/29/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing Other Serious 7/2/2003 55 Male 187 lb 6/29/2010 United States
Primary
Secondary
Concomitant
Small Intestinal Perforation Other Serious 6/28/2010 Physician Japan
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 1/13/2010 38 Male 6/28/2010 Physician United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 79 Female 7/9/2010 United States
Primary
Concomitant
Subdural Haemorrhage Other Serious 2/12/2010 70 Male 7/28/2010 Other Health Professional Ireland
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 7/29/2010 United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 8/16/2010 Japan
Primary
Concomitant
Thrombocytopenia Other Serious 6 Male 8/20/2010
Primary
Secondary
Weight Decreased Other Serious 10/1/2003 42 Male 206 lb 9/10/2010 Other Health Professional United States
Primary
Concomitant
Wound Infection Staphylococcal Other Serious 9/1/2007 75 Male 225 lb 9/23/2010 Lawyer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 6/14/2010 78 Male 101 lb 9/23/2010 Pharmacist Japan
Primary
Concomitant
Drug Interaction Other Serious 70 Male 9/24/2010 Other Health Professional China
Primary
Concomitant
Interacting
Wheezing Other Serious 7/2/2003 55 Male 187 lb 9/24/2010 United States
Primary
Secondary
Concomitant
Porokeratosis Other Serious 63 Male 10/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/1/2010 79 Female 165 lb 10/19/2010 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 3/16/2008 82 Female 174 lb 11/2/2010 Lawyer United States
Primary
Secondary
Concomitant
Haematuria Hospitalization 10/16/2010 22 Female 132 lb 11/9/2010 Physician United States
Primary
Secondary
Thrombosis In Device Other Serious 46 Female 11/15/2010
Primary
Secondary
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 11/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/1/2005 56 Female 123 lb 12/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Cardiac Arrest Death 9/1/2009 Female 88 lb 12/31/2010 Physician Japan
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2009 40 Female 311 lb 1/3/2011 Physician United States
Primary
Secondary
Concomitant
Complications Of Transplanted Kidney Hospitalization 10/16/2010 22 Female 132 lb 1/12/2011 Physician United States
Primary
Secondary
Pleural Effusion Other Serious 11/1/2005 56 Female 123 lb 1/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 45 Male 1/18/2011 Pharmacist United States
Primary
Concomitant
Left Ventricular Dysfunction Hospitalization 45 Male 1/19/2011 Other Health Professional United States
Primary
Concomitant
Chorioamnionitis Death Female 4 lb 1/21/2011 Other Health Professional South Africa
Primary
Secondary
Maternal Drugs Affecting Foetus Other Serious Male 1/21/2011 Other Health Professional South Africa
Primary
Secondary
Drug Interaction Other Serious 70 Male 1/21/2011 Other Health Professional China
Primary
Concomitant
Interacting
Haemoglobin Decreased Hospitalization 74 Male 1/24/2011 Other Health Professional Turkey
Primary
Concomitant
Cardiac Arrest Death 9/1/2009 Female 88 lb 2/1/2011 Physician Japan
Primary
Concomitant
Ischaemic Cardiomyopathy Hospitalization 82 Male 1/27/2011 United States
Primary
Concomitant
Tricuspid Valve Incompetence Death 67 Male 1/26/2011 United States
Primary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/9/2011 Pharmacist United States
Primary
Concomitant
Hypotension Hospitalization 12/23/2010 70 Male 271 lb 3/14/2011 Physician United States
Primary
Secondary
Concomitant
Shock Haemorrhagic Life Threatening 5/24/2010 73 Male 115 lb 3/15/2011 Physician Japan
Primary
Concomitant
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 3/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Urticaria Other Serious 12/9/2010 50 Male 225 lb 3/15/2011 Pharmacist United States
Primary
Concomitant
Hypoaesthesia Other Serious 7/2/2003 55 Male 187 lb 3/17/2011 United States
Primary
Secondary
Concomitant
Circulatory Collapse Life Threatening 5/24/2010 73 Male 115 lb 3/18/2011 Physician Japan
Primary
Concomitant
Shock Haemorrhagic Life Threatening 5/24/2010 73 Male 115 lb 3/23/2011 Physician Japan
Primary
Concomitant
Unevaluable Event Hospitalization 3/14/2004 77 Male 200 lb 3/25/2011 Other Health Professional United States
Primary
Concomitant
Injury Hospitalization 3/14/2004 77 Male 200 lb 3/25/2011 Consumer United States
Primary
Concomitant
Anhedonia Hospitalization 12/15/2005 56 Male 146 lb 4/18/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 44 Male 190 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Stress Other Serious 7/6/2007 75 Male 145 lb 4/19/2011 Lawyer United States
Primary
Concomitant
Depression Death 63 Female 110 lb 4/21/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 84 Female 4/21/2011 Other Health Professional France
Primary
Secondary
Renal Failure Acute Death 63 Female 110 lb 4/25/2011 Physician United States
Primary
Concomitant
Retroperitoneal Haemorrhage Hospitalization 3/13/2011 65 Male 190 lb 4/11/2011 Pharmacist United States
Primary
Secondary
Cellulitis Hospitalization 3/7/2009 71 Male 112 lb 4/28/2011 Physician Japan
Primary
Secondary
Concomitant
Chills Death 3/6/2011 4/29/2011 Physician United States
Primary
Secondary
Concomitant
Pain Death 1/1/2007 73 Female 168 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Glomerulonephritis Membranous Other Serious 80 Male 5/4/2011 Other Health Professional Japan
Primary
Secondary
Interacting
Pain Hospitalization 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 42 Female 137 lb 5/6/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious 1/9/2006 44 Male 190 lb 5/5/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 12/2/2005 74 Male 159 lb 5/6/2011 Consumer United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Death 2/12/2010 70 Male 5/5/2011 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 2/12/2010 70 Male 5/5/2011 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Death 11/14/2004 64 Female 110 lb 5/9/2011 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 10/8/2005 68 Female 148 lb 5/9/2011 Physician United States
Primary
Concomitant
Gallbladder Disorder Hospitalization 1/1/2004 42 Female 150 lb 5/9/2011 Other Health Professional United States
Primary
Concomitant
Asthenia Other Serious 1/1/2005 54 Female 140 lb 5/10/2011 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/23/2006 51 Female 141 lb 5/10/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Hospitalization 8/1/2004 74 Female 114 lb 5/10/2011 Consumer Germany
Primary
Secondary
Concomitant
Injury Death 3/3/2000 84 Female 110 lb 5/12/2011 Other Health Professional United States
Primary
Concomitant
Muscular Weakness Other Serious 57 Male 173 lb 7/22/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 1/7/2011 82 Female 7/31/2011 Pharmacist United States
Primary
Concomitant
Sepsis Other Serious 4/28/2011 71 Male 8/1/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 7/6/2007 75 Male 146 lb 8/11/2011 Lawyer United States
Primary
Concomitant
Fear Hospitalization 1/31/2007 72 Male 205 lb 9/7/2011 Consumer United States
Primary
Concomitant
Fear Hospitalization 1/31/2007 72 Male 205 lb 9/7/2011 Other Health Professional United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 6/1/2011 63 Female 120 lb 10/28/2011 Consumer United States
Primary
Concomitant
Platelet Count Decreased Other Serious 9/30/2011 81 Female 11/14/2011 Pharmacist Japan
Primary
Concomitant
Nausea Hospitalization 6/1/2011 63 Female 120 lb 11/15/2011 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 6/1/2011 63 Female 120 lb 12/13/2011 Consumer United States
Primary
Concomitant
Hepatic Function Abnormal Other Serious 51 Male 2/20/2012 Physician Japan
Primary
Secondary
Cerebral Haemorrhage Death 5/26/2011 79 Male 2/21/2012 Physician Japan
Primary
Concomitant
Pain Hospitalization 7/21/2009 29 Female 262 lb 3/26/2012 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 7/16/2011 51 Male 139 lb 4/23/2012 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 5/16/2010 78 Male 132 lb 5/23/2012 Physician Japan
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/20/2011 40 Male 152 lb 5/31/2012 Physician Japan
Primary
Secondary
Concomitant
Emphysema Other Serious 65 Male 218 lb 6/11/2012 Consumer United States
Primary
Concomitant
Anaemia Other Serious 6/6/2009 77 Female 93 lb 6/12/2012 Physician Japan
Primary
Concomitant
Gliosis Other Serious 11/1/2002 51 Female 177 lb 8/3/2012 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 6/6/2012 73 Male 219 lb 10/11/2012 Other Health Professional Ca
Primary
Secondary
Concomitant
Vessel Puncture Site Haemorrhage Hospitalization 3/8/2010 85 Female 101 lb 10/15/2012 Physician Jp
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 11/14/2012 Pharmacist Gb
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 6/2/2012 79 Female 122 lb 8/30/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Large Intestine Polyp Hospitalization 3/9/2010 61 Male 168 lb 12/4/2012 Physician Jp
Primary
Concomitant

Drug Data